Motif ID: Klf13

Z-value: 0.397


Transcription factors associated with Klf13:

Gene SymbolEntrez IDGene Name
Klf13 ENSMUSG00000052040.9 Klf13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf13mm10_v2_chr7_-_63938862_639389330.029.2e-01Click!


Activity profile for motif Klf13.

activity profile for motif Klf13


Sorted Z-values histogram for motif Klf13

Sorted Z-values for motif Klf13



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf13

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_56722372 1.426 ENSMUST00000038949.4
 Adrb1
adrenergic receptor, beta 1
chr17_+_87282880 1.056 ENSMUST00000041110.5
ENSMUST00000125875.1
 Ttc7

tetratricopeptide repeat domain 7

chr17_-_87282771 0.923 ENSMUST00000161759.1
 4833418N02Rik
RIKEN cDNA 4833418N02 gene
chr15_-_64922290 0.768 ENSMUST00000023007.5
 Adcy8
adenylate cyclase 8
chr4_+_136143497 0.717 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr17_-_87282793 0.697 ENSMUST00000146560.2
 4833418N02Rik
RIKEN cDNA 4833418N02 gene
chr18_+_37955544 0.623 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
 Rell2




RELT-like 2




chr11_+_70026815 0.605 ENSMUST00000135916.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr18_+_37955126 0.585 ENSMUST00000176902.1
ENSMUST00000176104.1
 Rell2

RELT-like 2

chr5_+_35757875 0.490 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
 Ablim2



actin-binding LIM protein 2



chr12_-_14152038 0.470 ENSMUST00000020926.6
 Fam84a
family with sequence similarity 84, member A
chr14_+_54426902 0.462 ENSMUST00000010550.7
 Mrpl52
mitochondrial ribosomal protein L52
chr19_-_42129043 0.407 ENSMUST00000018965.3
 Avpi1
arginine vasopressin-induced 1
chr7_+_19181159 0.404 ENSMUST00000120595.1
ENSMUST00000048502.8
 Eml2

echinoderm microtubule associated protein like 2

chr8_+_3631109 0.403 ENSMUST00000004745.8
 Stxbp2
syntaxin binding protein 2
chr15_+_85037062 0.376 ENSMUST00000023069.7
 Fam118a
family with sequence similarity 118, member A
chr10_-_62340514 0.365 ENSMUST00000099691.4
 Hk1
hexokinase 1
chr12_-_79172609 0.365 ENSMUST00000055262.6
 Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr8_+_83608175 0.333 ENSMUST00000005620.8
 Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_-_82652856 0.325 ENSMUST00000160281.1
ENSMUST00000095786.5
 Pole4

polymerase (DNA-directed), epsilon 4 (p12 subunit)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.4 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.0 1.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.7 GO:0030903 notochord development(GO:0030903)
0.0 0.6 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.3 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0089701 U2AF(GO:0089701)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.4 GO:0051379 epinephrine binding(GO:0051379)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.7 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.8 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols