Motif ID: Klf8

Z-value: 0.491


Transcription factors associated with Klf8:

Gene SymbolEntrez IDGene Name
Klf8 ENSMUSG00000041649.7 Klf8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf8mm10_v2_chrX_+_153237748_153237748-0.153.7e-01Click!


Activity profile for motif Klf8.

activity profile for motif Klf8


Sorted Z-values histogram for motif Klf8

Sorted Z-values for motif Klf8



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_142657466 1.015 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr6_+_114131229 0.882 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr2_-_36105271 0.812 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr19_+_5740885 0.808 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr11_-_32222233 0.774 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr12_+_84009481 0.756 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr7_-_31054815 0.728 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr6_+_5725639 0.708 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr11_-_116654245 0.689 ENSMUST00000021166.5
Cygb
cytoglobin
chr1_-_184883218 0.676 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr1_-_33907721 0.638 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr19_+_8664005 0.632 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr2_-_165473187 0.622 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr7_-_31055594 0.621 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr1_+_172499948 0.581 ENSMUST00000111230.1
Tagln2
transgelin 2
chr16_+_30599717 0.564 ENSMUST00000059078.3
Fam43a
family with sequence similarity 43, member A
chr5_-_123132651 0.556 ENSMUST00000031401.5
Rhof
ras homolog gene family, member f
chr2_-_168741898 0.545 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr18_-_78206408 0.538 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_-_103843685 0.532 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr13_+_49187485 0.525 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr7_-_57509995 0.519 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr1_+_75507077 0.505 ENSMUST00000037330.4
Inha
inhibin alpha
chr7_+_110627650 0.495 ENSMUST00000033054.8
Adm
adrenomedullin
chr15_-_75566811 0.491 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr15_+_78926720 0.483 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr17_+_34898931 0.477 ENSMUST00000097342.3
ENSMUST00000013931.5
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr3_+_90541146 0.471 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr11_+_69632927 0.465 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr12_-_25096080 0.462 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr10_-_127666598 0.454 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr15_-_75567176 0.449 ENSMUST00000156032.1
ENSMUST00000127095.1
Ly6h

lymphocyte antigen 6 complex, locus H

chr18_-_74961252 0.447 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr7_+_100495987 0.436 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_85832551 0.436 ENSMUST00000000095.6
Tbx2
T-box 2
chr4_+_148160613 0.436 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr14_-_30353468 0.429 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_-_31042078 0.429 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
Fxyd5






FXYD domain-containing ion transport regulator 5






chr7_+_19004047 0.426 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr5_+_139423151 0.426 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr13_-_60177357 0.425 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr6_+_115134899 0.419 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr7_+_4119525 0.402 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr15_+_80091320 0.397 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr7_+_4119556 0.393 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr7_-_127026479 0.386 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_+_54949388 0.377 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr4_+_141368116 0.375 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr15_+_78406695 0.361 ENSMUST00000167140.1
Mpst
mercaptopyruvate sulfurtransferase
chr16_+_93683184 0.343 ENSMUST00000039620.6
Cbr3
carbonyl reductase 3
chr13_-_55488038 0.341 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
Dbn1


drebrin 1


chr2_+_30416096 0.341 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr15_+_78406777 0.340 ENSMUST00000169133.1
Mpst
mercaptopyruvate sulfurtransferase
chr10_+_99263224 0.339 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr11_-_102296618 0.338 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr4_+_127169131 0.330 ENSMUST00000046659.7
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr17_-_27820445 0.330 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chr8_+_110721462 0.329 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr11_+_75655873 0.325 ENSMUST00000108431.2
Myo1c
myosin IC
chr7_-_93081027 0.325 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr8_+_114205590 0.325 ENSMUST00000049509.6
ENSMUST00000150963.1
Vat1l

vesicle amine transport protein 1 homolog-like (T. californica)

chr17_-_25868727 0.324 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr2_-_118703963 0.315 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chrX_+_56963325 0.315 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr11_+_114851814 0.313 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
Gprc5c


G protein-coupled receptor, family C, group 5, member C


chr11_+_70647258 0.311 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr2_+_30416031 0.309 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr7_-_27396542 0.307 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr15_-_97767644 0.306 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr10_-_84440591 0.305 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr1_+_36511867 0.304 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr19_+_47228804 0.299 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr11_-_102897146 0.294 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr7_+_82337218 0.293 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr1_-_20820213 0.293 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr2_+_27886416 0.291 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr17_+_34898463 0.282 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr6_-_122820606 0.281 ENSMUST00000181317.1
Gm26826
predicted gene, 26826
chr1_-_75506331 0.271 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr15_+_39006272 0.271 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr9_-_45936049 0.265 ENSMUST00000034590.2
Tagln
transgelin
chr10_+_116301374 0.263 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr17_-_27820534 0.261 ENSMUST00000075076.4
ENSMUST00000114863.2
D17Wsu92e

DNA segment, Chr 17, Wayne State University 92, expressed

chrX_-_73921917 0.260 ENSMUST00000114389.3
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr4_+_97777780 0.253 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr2_-_168742100 0.251 ENSMUST00000109177.1
Atp9a
ATPase, class II, type 9A
chrM_-_14060 0.251 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr8_-_69887687 0.251 ENSMUST00000057831.7
Cilp2
cartilage intermediate layer protein 2
chr2_-_27142429 0.246 ENSMUST00000151224.2
Fam163b
family with sequence similarity 163, member B
chr15_-_97767798 0.244 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr7_+_24884611 0.241 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr7_-_139582790 0.241 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr10_-_80798476 0.237 ENSMUST00000036805.5
Plekhj1
pleckstrin homology domain containing, family J member 1
chr11_-_35980473 0.236 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr5_-_140649018 0.232 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)
chr8_-_105264586 0.231 ENSMUST00000034359.3
Tradd
TNFRSF1A-associated via death domain
chr7_+_24884651 0.229 ENSMUST00000153451.2
ENSMUST00000108429.1
Rps19

ribosomal protein S19

chr11_-_62539257 0.226 ENSMUST00000018653.1
Cenpv
centromere protein V
chr17_-_57247632 0.226 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr15_-_97767244 0.225 ENSMUST00000146620.1
Rapgef3
Rap guanine nucleotide exchange factor (GEF) 3
chr15_-_89355655 0.225 ENSMUST00000023283.5
Lmf2
lipase maturation factor 2
chr15_+_103453782 0.222 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr15_+_78428564 0.222 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
Kctd17


potassium channel tetramerisation domain containing 17


chr2_-_3419066 0.216 ENSMUST00000115082.3
Meig1
meiosis expressed gene 1
chrX_-_73921930 0.215 ENSMUST00000033763.8
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr4_-_150914401 0.214 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chrX_-_73921828 0.214 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr10_-_80399478 0.213 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr13_-_43560174 0.212 ENSMUST00000021800.4
Mcur1
mitochondrial calcium uniporter regulator 1
chr1_+_191098414 0.211 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr7_+_45705518 0.211 ENSMUST00000107740.1
ENSMUST00000107741.1
Dbp

D site albumin promoter binding protein

chr10_-_58675631 0.208 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr2_+_28205648 0.207 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr11_+_32286946 0.205 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr8_+_93810832 0.200 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr7_-_43489967 0.198 ENSMUST00000107974.1
Iglon5
IgLON family member 5
chr14_-_31128924 0.197 ENSMUST00000064032.4
ENSMUST00000049732.5
ENSMUST00000090205.3
Smim4


small itegral membrane protein 4


chrX_-_73659724 0.196 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr17_-_45549655 0.195 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr16_-_94370450 0.193 ENSMUST00000138514.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr15_-_89373810 0.192 ENSMUST00000167643.2
Sco2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr7_-_27355944 0.190 ENSMUST00000003857.6
Shkbp1
Sh3kbp1 binding protein 1
chr5_-_31047998 0.189 ENSMUST00000114665.1
ENSMUST00000006817.4
Slc5a6

solute carrier family 5 (sodium-dependent vitamin transporter), member 6

chr11_+_49244191 0.188 ENSMUST00000167400.1
ENSMUST00000081794.6
Mgat1

mannoside acetylglucosaminyltransferase 1

chr6_-_72788952 0.185 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr17_-_7827289 0.185 ENSMUST00000167580.1
ENSMUST00000169126.1
Fndc1

fibronectin type III domain containing 1

chr5_+_24452177 0.179 ENSMUST00000024123.4
Agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr10_+_80798652 0.179 ENSMUST00000151928.1
Sf3a2
splicing factor 3a, subunit 2
chr9_-_8004585 0.177 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr2_-_3419019 0.175 ENSMUST00000115084.1
ENSMUST00000115083.1
Meig1

meiosis expressed gene 1

chr2_-_130642770 0.175 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr19_+_37550397 0.170 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr6_+_43265582 0.170 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr11_-_69801716 0.165 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr17_+_46646225 0.164 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr3_+_94377432 0.162 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr9_-_82975475 0.160 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr15_-_83149307 0.157 ENSMUST00000100375.4
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr11_-_109473220 0.156 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_63938862 0.156 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr11_-_67922136 0.156 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr10_-_116473418 0.156 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr7_+_141061274 0.155 ENSMUST00000048002.5
B4galnt4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr13_-_32802849 0.154 ENSMUST00000057911.1
D930007J09Rik
RIKEN cDNA D930007J09 gene
chr1_+_192190771 0.154 ENSMUST00000078470.5
ENSMUST00000110844.1
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr4_-_154160632 0.153 ENSMUST00000105639.3
ENSMUST00000030896.8
Tprgl

transformation related protein 63 regulated like

chr4_-_155345696 0.153 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr11_+_114851507 0.152 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr1_-_75505641 0.152 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chr6_+_124931378 0.151 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr7_-_80905060 0.151 ENSMUST00000119428.1
ENSMUST00000026817.4
Nmb

neuromedin B

chr13_+_73604002 0.151 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chrX_-_51205990 0.150 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr7_+_144838590 0.149 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr5_-_143269958 0.147 ENSMUST00000161448.1
Zfp316
zinc finger protein 316
chr9_+_66158206 0.147 ENSMUST00000034944.2
Dapk2
death-associated protein kinase 2
chr11_-_69948145 0.146 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr2_-_54085542 0.143 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_+_29619692 0.143 ENSMUST00000095087.4
ENSMUST00000091146.5
ENSMUST00000102872.4
Rapgef1


Rap guanine nucleotide exchange factor (GEF) 1


chr1_+_92831614 0.140 ENSMUST00000045970.6
Gpc1
glypican 1
chr8_-_84147858 0.139 ENSMUST00000117424.2
ENSMUST00000040383.8
Cc2d1a

coiled-coil and C2 domain containing 1A

chr11_-_86683761 0.139 ENSMUST00000018315.3
Vmp1
vacuole membrane protein 1
chr7_+_29238434 0.139 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_24076529 0.134 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr9_-_58202281 0.133 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr18_-_38250157 0.131 ENSMUST00000181871.1
1700086O06Rik
RIKEN cDNA 1700086O06 gene
chr15_+_89355730 0.131 ENSMUST00000074552.5
ENSMUST00000088717.6
Ncaph2

non-SMC condensin II complex, subunit H2

chr11_+_119942763 0.127 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr16_-_94370647 0.126 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_99535652 0.125 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr4_+_133039482 0.125 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr9_+_58134535 0.125 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr5_-_31048014 0.124 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr7_+_112427706 0.122 ENSMUST00000033030.7
Parva
parvin, alpha
chr19_+_42090422 0.121 ENSMUST00000066778.4
Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr3_+_87906321 0.120 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr15_-_75909543 0.120 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr2_-_32381909 0.119 ENSMUST00000048792.4
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr7_-_29125142 0.119 ENSMUST00000179893.1
ENSMUST00000032813.9
Ryr1

ryanodine receptor 1, skeletal muscle

chr12_+_81859964 0.118 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr15_+_81744848 0.117 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr1_-_153900198 0.117 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr15_+_89355716 0.117 ENSMUST00000036987.5
Ncaph2
non-SMC condensin II complex, subunit H2
chr11_-_75796048 0.113 ENSMUST00000021209.7
Doc2b
double C2, beta
chr17_+_24696234 0.112 ENSMUST00000019464.7
Noxo1
NADPH oxidase organizer 1
chr2_-_168590315 0.111 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr2_-_153225396 0.111 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr12_-_79172609 0.111 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr7_-_126200397 0.109 ENSMUST00000009344.9
Xpo6
exportin 6
chr7_+_25306085 0.109 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr10_-_13388753 0.109 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr11_+_114765363 0.108 ENSMUST00000138804.1
ENSMUST00000084368.5
Kif19a

kinesin family member 19A

chr5_-_101665195 0.107 ENSMUST00000044125.8
Nkx6-1
NK6 homeobox 1
chr6_-_115251839 0.107 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr8_+_84148025 0.106 ENSMUST00000143833.1
ENSMUST00000118856.1
4930432K21Rik

RIKEN cDNA 4930432K21 gene

chr2_-_175800961 0.104 ENSMUST00000123863.1
ENSMUST00000109020.2
Gm14288

predicted gene 14288

chr7_+_30565410 0.104 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr11_-_109472611 0.103 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_69695521 0.103 ENSMUST00000181261.1
Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
chr19_-_29361824 0.101 ENSMUST00000126800.1
ENSMUST00000152936.1
ENSMUST00000143467.1
ENSMUST00000016639.5
Plgrkt



plasminogen receptor, C-terminal lysine transmembrane protein




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 0.8 GO:0036166 phenotypic switching(GO:0036166)
0.2 1.3 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.2 0.8 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.2 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.2 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.4 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.1 0.5 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.7 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.4 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.5 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.1 0.3 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:2001016 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.4 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.0 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.2 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0 0.2 GO:0060242 contact inhibition(GO:0060242)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0046864 retinol transport(GO:0034633) nose morphogenesis(GO:0043585) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.5 GO:0060384 innervation(GO:0060384)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.0 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 0.7 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.2 0.8 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.2 0.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 2.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 0.7 GO:0004096 catalase activity(GO:0004096)
0.2 0.5 GO:0005118 sevenless binding(GO:0005118)
0.1 0.7 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.7 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 2.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 0.9 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.5 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation