Motif ID: Lef1

Z-value: 1.717


Transcription factors associated with Lef1:

Gene SymbolEntrez IDGene Name
Lef1 ENSMUSG00000027985.8 Lef1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lef1mm10_v2_chr3_+_131110350_1311104710.581.6e-04Click!


Activity profile for motif Lef1.

activity profile for motif Lef1


Sorted Z-values histogram for motif Lef1

Sorted Z-values for motif Lef1



Network of associatons between targets according to the STRING database.



First level regulatory network of Lef1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_98169542 11.455 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr2_+_70474923 11.437 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr10_-_92165159 10.211 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr7_-_37772868 10.064 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr7_-_115824699 9.262 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr18_-_62756275 8.800 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr19_+_55742242 7.868 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr7_-_37773555 7.287 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr3_+_102010138 6.778 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr2_+_116067213 6.573 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr4_+_8691303 6.335 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr5_-_28210022 6.264 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr4_-_91376490 6.122 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_116067391 6.091 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr4_-_91376433 6.062 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr1_-_165934900 5.978 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr7_-_116038734 5.809 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr1_-_186705980 5.716 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr4_-_24430838 5.504 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr7_-_37769624 5.374 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr1_-_138842429 5.266 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr17_-_70851189 5.192 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr4_-_34882919 5.168 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr4_-_63403330 5.091 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr7_+_45216671 5.016 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr12_+_76072016 4.819 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr18_-_84086379 4.737 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr10_-_92164666 4.554 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr3_-_116968827 4.507 ENSMUST00000119557.1
Palmd
palmdelphin
chr1_+_165788681 4.501 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr5_+_17574726 4.486 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_-_82705735 4.450 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr3_-_116424007 4.408 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chrX_+_129749740 4.236 ENSMUST00000167619.2
ENSMUST00000037854.8
Diap2

diaphanous homolog 2 (Drosophila)

chr3_-_116423930 4.233 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr9_-_71896047 4.195 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr2_+_152081529 4.158 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr13_+_104287855 4.105 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr3_-_116968969 3.960 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr3_-_75956888 3.939 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr1_+_165788746 3.925 ENSMUST00000161559.2
Cd247
CD247 antigen
chr2_+_124610573 3.916 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr6_-_148944750 3.910 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr8_+_45507768 3.870 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr3_-_57575760 3.857 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr11_+_88068242 3.824 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr11_-_98053415 3.780 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr3_+_131110350 3.764 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr4_+_97777780 3.754 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr6_+_15185456 3.750 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr2_-_60125651 3.656 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr4_-_97778042 3.623 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_+_55406163 3.542 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr16_+_43508118 3.535 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_5218546 3.535 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr2_-_18048784 3.518 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr3_-_57575907 3.477 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr2_-_18048347 3.463 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr19_+_55741810 3.431 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr16_+_20097554 3.410 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr19_+_55741884 3.391 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr2_-_116065047 3.354 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chr3_+_5218516 3.347 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr6_+_83137089 3.342 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chrX_+_129749830 3.342 ENSMUST00000113320.2
Diap2
diaphanous homolog 2 (Drosophila)
chr18_+_82914632 3.331 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr2_+_181767283 3.329 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chrX_+_109095359 3.323 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr17_-_51810866 3.285 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr16_+_96200666 3.257 ENSMUST00000123728.3
ENSMUST00000171181.2
ENSMUST00000166952.1
ENSMUST00000132424.2
Sh3bgr



SH3-binding domain glutamic acid-rich protein



chr2_+_181767040 3.221 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr1_-_163725123 3.218 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr4_-_97584612 3.177 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_70366735 3.158 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_+_35076902 3.069 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr11_+_108920800 3.004 ENSMUST00000140821.1
Axin2
axin2
chr4_-_97584605 3.003 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_102925086 3.003 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr10_-_18743691 2.999 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr17_+_35077080 2.996 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr12_+_52516077 2.987 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr1_+_136131382 2.949 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr4_+_108479081 2.947 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr9_+_91368970 2.925 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr3_-_108226598 2.885 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr6_+_29735667 2.883 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr7_-_73541738 2.864 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr9_+_91368811 2.814 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr18_-_23038656 2.783 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr1_+_6734827 2.770 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr12_-_73113407 2.764 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr19_+_55895508 2.763 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_153031852 2.750 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr12_+_29938036 2.741 ENSMUST00000122328.1
ENSMUST00000118321.1
Pxdn

peroxidasin homolog (Drosophila)

chr5_+_47984793 2.732 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2



slit homolog 2 (Drosophila)



chr12_-_54986363 2.708 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr15_-_84855093 2.696 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr18_+_82910863 2.667 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr9_+_74976096 2.637 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr12_-_54986328 2.634 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr18_+_11633276 2.611 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr3_+_5218589 2.580 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr19_+_55742056 2.567 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_+_96259246 2.537 ENSMUST00000179065.1
ENSMUST00000165768.2
Tfdp2

transcription factor Dp 2

chr4_-_20778527 2.529 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr10_-_5805412 2.513 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr2_+_146221921 2.501 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr1_+_74391479 2.474 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr11_+_108921648 2.468 ENSMUST00000144511.1
Axin2
axin2
chr9_+_22454290 2.467 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr12_-_98737405 2.423 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr12_+_119945957 2.423 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr2_-_26092149 2.413 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr5_+_47984571 2.402 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr5_-_112228633 2.401 ENSMUST00000182699.1
ENSMUST00000182258.1
ENSMUST00000183036.1
Miat


myocardial infarction associated transcript (non-protein coding)


chr15_-_72034202 2.386 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr6_+_53573364 2.353 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr11_+_108920342 2.328 ENSMUST00000052915.7
Axin2
axin2
chr11_-_88718078 2.293 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr14_+_55824795 2.285 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr7_+_82867327 2.239 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr10_+_94036001 2.149 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr4_+_116557658 2.144 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr10_-_95324072 2.104 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr15_-_50889691 2.081 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr14_+_54259227 2.079 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr3_-_108210438 2.062 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr5_-_28210168 2.045 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr17_+_53566971 2.032 ENSMUST00000000724.8
Kat2b
K(lysine) acetyltransferase 2B
chr15_-_58214882 2.012 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr19_-_30549516 1.995 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr11_+_117332335 1.985 ENSMUST00000106349.1
Sept9
septin 9
chr19_-_4334001 1.928 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr13_-_113046357 1.923 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr12_+_76370266 1.887 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr6_+_65042575 1.887 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_+_58134535 1.885 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr16_-_64786321 1.841 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr4_+_43875524 1.834 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr12_+_71048338 1.823 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chrX_+_18162575 1.818 ENSMUST00000044484.6
ENSMUST00000052368.8
Kdm6a

lysine (K)-specific demethylase 6A

chr4_-_126468580 1.818 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr9_+_119402444 1.801 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr14_-_55106547 1.791 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr19_-_37330613 1.786 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr5_-_138155694 1.777 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr3_-_51560816 1.769 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr2_+_15055274 1.765 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr14_+_12189943 1.755 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr1_+_59482133 1.753 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr13_+_14063776 1.713 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr12_+_111039334 1.712 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr9_+_54863742 1.699 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr2_-_172370506 1.695 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr17_+_47630690 1.680 ENSMUST00000024779.8
Usp49
ubiquitin specific peptidase 49
chr18_-_15403680 1.663 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr1_-_163313661 1.656 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr13_-_29984219 1.643 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr12_-_119238794 1.630 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr14_+_69029289 1.630 ENSMUST00000014957.8
Stc1
stanniocalcin 1
chr4_+_116558056 1.623 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr13_-_75943812 1.596 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr5_+_57718021 1.577 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr2_+_92185438 1.548 ENSMUST00000128781.2
Phf21a
PHD finger protein 21A
chr16_-_91044473 1.536 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr9_-_96752822 1.521 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr11_-_49712674 1.504 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6

CCR4-NOT transcription complex, subunit 6

chr2_+_92185467 1.497 ENSMUST00000111291.2
Phf21a
PHD finger protein 21A
chr4_-_20778852 1.497 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr1_-_155972887 1.481 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr14_+_46760526 1.476 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr17_-_47924400 1.471 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr15_+_34238026 1.467 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr17_-_47924460 1.428 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr18_+_69593361 1.409 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr5_+_108065742 1.392 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr7_+_44896125 1.370 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr12_-_51829525 1.368 ENSMUST00000179265.1
ENSMUST00000042052.8
Hectd1

HECT domain containing 1

chr14_+_47663756 1.368 ENSMUST00000022391.7
Ktn1
kinectin 1
chr2_-_173276526 1.350 ENSMUST00000036248.6
Pmepa1
prostate transmembrane protein, androgen induced 1
chr1_-_181183739 1.340 ENSMUST00000159290.1
Wdr26
WD repeat domain 26
chr19_+_60889749 1.340 ENSMUST00000003313.8
Grk5
G protein-coupled receptor kinase 5
chr6_-_97459279 1.325 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr8_+_79028317 1.291 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr8_+_31111816 1.268 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr2_+_18055203 1.265 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr9_+_31030621 1.238 ENSMUST00000115222.2
Zbtb44
zinc finger and BTB domain containing 44
chr9_-_122903102 1.231 ENSMUST00000180877.1
ENSMUST00000180486.1
A530083I20Rik

RIKEN cDNA A530083I20 gene

chr3_+_20057802 1.231 ENSMUST00000002502.5
Hltf
helicase-like transcription factor
chr5_+_92137896 1.222 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr2_-_65567505 1.217 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_-_86733218 1.202 ENSMUST00000113679.1
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr7_-_78578308 1.192 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_78577771 1.165 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr17_-_88065028 1.157 ENSMUST00000130379.1
Fbxo11
F-box protein 11
chr5_+_108065696 1.131 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr17_-_88065291 1.127 ENSMUST00000005504.8
Fbxo11
F-box protein 11
chr2_-_180889660 1.113 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr13_-_98926374 1.109 ENSMUST00000109401.1
Tnpo1
transportin 1
chr13_+_80883403 1.107 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
2.6 7.8 GO:0061181 regulation of chondrocyte development(GO:0061181)
2.6 20.7 GO:0048625 myoblast fate commitment(GO:0048625)
2.1 6.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.9 5.7 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
1.8 28.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.7 5.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
1.6 4.7 GO:0060023 soft palate development(GO:0060023)
1.4 2.9 GO:0060242 contact inhibition(GO:0060242)
1.4 15.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.3 2.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.3 3.8 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.3 2.5 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
1.1 3.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
1.1 4.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.1 5.3 GO:0035262 gonad morphogenesis(GO:0035262)
1.1 4.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.0 7.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.0 5.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.0 6.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.9 8.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.8 2.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.8 2.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.8 2.3 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.7 4.5 GO:0003350 pulmonary myocardium development(GO:0003350)
0.7 3.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.7 0.7 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.7 7.6 GO:0060539 diaphragm development(GO:0060539)
0.7 2.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.7 2.0 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.6 3.2 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.6 3.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.6 1.8 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.6 1.7 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.5 2.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 12.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.5 2.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.5 2.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.5 1.9 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 1.7 GO:0070295 renal water absorption(GO:0070295)
0.4 2.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.4 1.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.4 1.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.4 0.4 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.3 1.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.3 6.8 GO:0030903 notochord development(GO:0030903)
0.3 1.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 4.4 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.3 1.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 1.0 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.3 5.5 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.3 2.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.3 3.8 GO:0072189 ureter development(GO:0072189)
0.3 1.5 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.3 3.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 8.4 GO:0070207 protein homotrimerization(GO:0070207)
0.3 0.9 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.3 1.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 3.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 0.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 1.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.3 1.8 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 1.7 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 6.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 1.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 1.7 GO:0048664 neuron fate determination(GO:0048664)
0.2 6.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 1.8 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.2 2.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 1.0 GO:0046684 response to pyrethroid(GO:0046684)
0.2 3.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 1.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 2.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.9 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.2 3.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 1.5 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.2 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.8 GO:0070141 response to UV-A(GO:0070141)
0.2 2.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 5.1 GO:0009409 response to cold(GO:0009409)
0.1 1.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 2.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 3.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 2.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 4.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 1.0 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 4.1 GO:0035904 aorta development(GO:0035904)
0.1 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 2.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.8 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 9.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 2.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.2 GO:0006301 postreplication repair(GO:0006301)
0.1 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 1.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 3.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 4.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0072337 modified amino acid transport(GO:0072337)
0.0 1.8 GO:1901998 toxin transport(GO:1901998)
0.0 2.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.5 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.9 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.6 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 1.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.6 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 4.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.5 GO:0048864 stem cell development(GO:0048864)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 20.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
2.1 8.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.9 3.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.7 5.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.3 5.3 GO:0008623 CHRAC(GO:0008623)
0.6 5.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 3.0 GO:0000235 astral microtubule(GO:0000235)
0.3 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 3.4 GO:0030057 desmosome(GO:0030057)
0.2 2.9 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 4.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.8 GO:0070578 RISC-loading complex(GO:0070578)
0.2 3.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 3.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 2.0 GO:0031105 septin complex(GO:0031105)
0.1 2.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 4.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.0 GO:0032009 early phagosome(GO:0032009)
0.1 8.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 34.5 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.8 GO:0005871 kinesin complex(GO:0005871)
0.1 1.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 2.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.1 GO:0005844 polysome(GO:0005844)
0.0 7.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0030118 clathrin coat(GO:0030118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.4 11.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.4 5.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.4 21.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.2 25.3 GO:0045295 gamma-catenin binding(GO:0045295)
1.1 8.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.7 6.0 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.7 2.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.6 2.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.6 2.9 GO:0005113 patched binding(GO:0005113)
0.6 1.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.5 3.2 GO:0001972 retinoic acid binding(GO:0001972)
0.5 2.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 8.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 7.5 GO:0070411 I-SMAD binding(GO:0070411)
0.4 2.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.4 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 2.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 1.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 5.2 GO:0070410 co-SMAD binding(GO:0070410)
0.3 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 5.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.3 2.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 3.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 1.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 1.0 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2 1.7 GO:0015288 porin activity(GO:0015288)
0.2 1.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 4.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 10.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.7 GO:0043559 insulin binding(GO:0043559)
0.2 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 7.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 1.8 GO:0048185 activin binding(GO:0048185)
0.2 5.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 28.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 6.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 2.1 GO:0070513 death domain binding(GO:0070513)
0.2 3.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 5.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 2.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 4.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 6.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 39.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 4.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 1.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 2.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 5.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.9 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 2.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 45.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 17.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.3 7.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.3 2.0 PID_FOXO_PATHWAY FoxO family signaling
0.2 7.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 4.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 8.8 PID_E2F_PATHWAY E2F transcription factor network
0.1 2.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 2.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 5.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 4.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 4.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 2.1 PID_SHP2_PATHWAY SHP2 signaling
0.1 2.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.2 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 4.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 1.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.4 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 14.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 7.0 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4 5.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 6.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 10.4 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.2 1.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 3.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 4.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 5.1 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE Genes involved in Signaling by FGFR in disease
0.1 2.6 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 2.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.7 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 1.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.9 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis