• All motifs sorted by activity significance
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• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: Meox1

Z-value: 0.894

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_14621805	7.056	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr15_-_8710734	7.043	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_36811361	6.404	ENSMUST00000101534.1	Ptn	pleiotrophin
chr15_-_8710409	5.621	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_134747241	5.101	ENSMUST00000015138.9	Eln	elastin
chr7_-_140154712	4.487	ENSMUST00000059241.7	Sprn	shadow of prion protein
chr15_-_37458523	4.072	ENSMUST00000116445.2	Ncald	neurocalcin delta
chr5_+_107403496	4.008	ENSMUST00000049146.5	Ephx4	epoxide hydrolase 4
chr15_-_37459327	3.914	ENSMUST00000119730.1 ENSMUST00000120746.1	Ncald	neurocalcin delta
chr3_-_59220150	3.878	ENSMUST00000170388.1	P2ry12	purinergic receptor P2Y, G-protein coupled 12
chr15_+_92597104	3.769	ENSMUST00000035399.8	Pdzrn4	PDZ domain containing RING finger 4
chr4_-_14621494	3.764	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr8_+_66386292	3.709	ENSMUST00000039540.5 ENSMUST00000110253.2	March1	membrane-associated ring finger (C3HC4) 1
chr4_-_14621669	3.508	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr3_-_121263314	2.771	ENSMUST00000029777.7	Tmem56	transmembrane protein 56
chr14_-_103843685	2.719	ENSMUST00000172237.1	Ednrb	endothelin receptor type B
chr3_-_113577743	2.569	ENSMUST00000067980.5	Amy1	amylase 1, salivary
chr2_+_125136692	2.340	ENSMUST00000099452.2	Ctxn2	cortexin 2
chr9_-_95750335	2.332	ENSMUST00000053785.3	Trpc1	transient receptor potential cation channel, subfamily C, member 1
chr3_+_13946368	2.246	ENSMUST00000171075.1 ENSMUST00000108372.2	Ralyl	RALY RNA binding protein-like
chr9_+_34904913	2.106	ENSMUST00000045091.6	Kirrel3	kin of IRRE like 3 (Drosophila)
chr4_-_129440800	1.919	ENSMUST00000053042.5 ENSMUST00000106046.1	Zbtb8b	zinc finger and BTB domain containing 8b
chr14_+_27238018	1.868	ENSMUST00000049206.5	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3
chr18_+_12741324	1.802	ENSMUST00000115857.2 ENSMUST00000121018.1 ENSMUST00000119108.1	Cabyr	calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr11_-_82890541	1.767	ENSMUST00000092844.6 ENSMUST00000021033.9 ENSMUST00000018985.8	Rad51d	RAD51 homolog D
chr13_+_4233730	1.736	ENSMUST00000081326.6	Akr1c19	aldo-keto reductase family 1, member C19
chr4_+_152199805	1.733	ENSMUST00000105652.2	Acot7	acyl-CoA thioesterase 7
chr18_+_37300799	1.700	ENSMUST00000051754.1	Pcdhb3	protocadherin beta 3
chr18_+_37355271	1.601	ENSMUST00000051163.1	Pcdhb8	protocadherin beta 8
chr1_-_134955908	1.462	ENSMUST00000045665.6 ENSMUST00000086444.4 ENSMUST00000112163.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr5_+_19907502	1.449	ENSMUST00000101558.3	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_113829069	1.389	ENSMUST00000024005.7	Scg5	secretogranin V
chr7_+_30231884	1.384	ENSMUST00000019882.9	Polr2i	polymerase (RNA) II (DNA directed) polypeptide I
chr1_-_134955847	1.369	ENSMUST00000168381.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr18_-_3281036	1.361	ENSMUST00000049942.6 ENSMUST00000139537.1 ENSMUST00000124747.1	Crem	cAMP responsive element modulator
chr17_-_45659312	1.334	ENSMUST00000120717.1	Capn11	calpain 11
chr15_+_18818895	1.256	ENSMUST00000166873.2	Cdh10	cadherin 10
chrX_+_150547375	1.247	ENSMUST00000066337.6 ENSMUST00000112715.1	Alas2	aminolevulinic acid synthase 2, erythroid
chr3_-_116253467	1.230	ENSMUST00000090473.5	Gpr88	G-protein coupled receptor 88
chrX_+_153139941	1.223	ENSMUST00000039720.4 ENSMUST00000144175.2	Rragb	Ras-related GTP binding B
chr18_-_67245818	1.215	ENSMUST00000073054.3	Mppe1	metallophosphoesterase 1
chr10_+_116018213	1.208	ENSMUST00000063470.4	Ptprr	protein tyrosine phosphatase, receptor type, R
chr11_-_98053415	1.191	ENSMUST00000017544.2	Stac2	SH3 and cysteine rich domain 2
chr2_-_110362985	1.186	ENSMUST00000099626.3	Fibin	fin bud initiation factor homolog (zebrafish)
chr9_+_94669876	1.160	ENSMUST00000033463.9	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr4_+_59035088	1.143	ENSMUST00000041160.6	Gng10	guanine nucleotide binding protein (G protein), gamma 10
chr17_-_47833169	1.120	ENSMUST00000131971.1 ENSMUST00000129360.1 ENSMUST00000113280.1 ENSMUST00000132125.1	Mdfi	MyoD family inhibitor
chr8_-_86580664	1.107	ENSMUST00000131423.1 ENSMUST00000152438.1	Abcc12	ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr16_-_92400067	1.097	ENSMUST00000023672.8	Rcan1	regulator of calcineurin 1
chr2_-_45117349	1.097	ENSMUST00000176438.2	Zeb2	zinc finger E-box binding homeobox 2
chr8_-_78821136	1.083	ENSMUST00000130325.1 ENSMUST00000051867.6	Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_54724474	1.078	ENSMUST00000175915.1	Wdr17	WD repeat domain 17
chr11_+_84129649	1.055	ENSMUST00000133811.1	Acaca	acetyl-Coenzyme A carboxylase alpha
chr9_-_55919605	1.043	ENSMUST00000037408.8	Scaper	S phase cyclin A-associated protein in the ER
chr17_-_47833256	1.028	ENSMUST00000152455.1 ENSMUST00000035375.7	Mdfi	MyoD family inhibitor
chr6_-_34317442	1.028	ENSMUST00000154655.1 ENSMUST00000102980.4	Akr1b3	aldo-keto reductase family 1, member B3 (aldose reductase)
chr5_+_144100387	0.994	ENSMUST00000041804.7	Lmtk2	lemur tyrosine kinase 2
chr7_+_79273201	0.956	ENSMUST00000037315.6	Abhd2	abhydrolase domain containing 2
chr5_+_19907774	0.953	ENSMUST00000115267.2	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_64947177	0.951	ENSMUST00000079896.7 ENSMUST00000026595.5	Tmem192	transmembrane protein 192
chr7_-_30232186	0.896	ENSMUST00000006254.5	Tbcb	tubulin folding cofactor B
chr7_+_30232032	0.869	ENSMUST00000149654.1	Polr2i	polymerase (RNA) II (DNA directed) polypeptide I
chr2_-_45112890	0.794	ENSMUST00000076836.6	Zeb2	zinc finger E-box binding homeobox 2
chr9_-_90255927	0.768	ENSMUST00000144646.1	Tbc1d2b	TBC1 domain family, member 2B
chr9_-_86880647	0.746	ENSMUST00000167014.1	Snap91	synaptosomal-associated protein 91
chr1_-_126738167	0.732	ENSMUST00000160693.1	Nckap5	NCK-associated protein 5
chr2_+_91650169	0.707	ENSMUST00000090614.4	Arhgap1	Rho GTPase activating protein 1
chr7_+_126950837	0.701	ENSMUST00000106332.1	Sez6l2	seizure related 6 homolog like 2
chr2_+_116067213	0.701	ENSMUST00000152412.1	G630016G05Rik	RIKEN cDNA G630016G05 gene
chr2_-_84425258	0.687	ENSMUST00000074262.2	Calcrl	calcitonin receptor-like
chr19_-_56548122	0.646	ENSMUST00000026063.5 ENSMUST00000182276.1	Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr2_-_120154600	0.640	ENSMUST00000028755.7	Ehd4	EH-domain containing 4
chr1_+_66468364	0.616	ENSMUST00000061620.9	Unc80	unc-80 homolog (C. elegans)
chr8_-_106573461	0.605	ENSMUST00000073722.5	Gm10073	predicted pseudogene 10073
chr11_+_121237216	0.590	ENSMUST00000103015.3	Narf	nuclear prelamin A recognition factor
chr2_+_91650116	0.576	ENSMUST00000111331.2	Arhgap1	Rho GTPase activating protein 1
chr8_+_105701142	0.570	ENSMUST00000098444.2	Pard6a	par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr5_-_122989260	0.550	ENSMUST00000118027.1	Kdm2b	lysine (K)-specific demethylase 2B
chr7_+_30232310	0.541	ENSMUST00000108193.1 ENSMUST00000108192.1	Polr2i	polymerase (RNA) II (DNA directed) polypeptide I
chr7_+_126776939	0.525	ENSMUST00000038614.5 ENSMUST00000170882.1 ENSMUST00000106359.1 ENSMUST00000106357.1 ENSMUST00000145762.1 ENSMUST00000132643.1 ENSMUST00000106356.1	Ypel3	yippee-like 3 (Drosophila)
chr5_-_62765618	0.522	ENSMUST00000159470.1	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_130730375	0.510	ENSMUST00000079085.6	Rpl34	ribosomal protein L34
chr17_-_24886304	0.508	ENSMUST00000044252.5	Nubp2	nucleotide binding protein 2
chr2_+_155751117	0.508	ENSMUST00000029140.5 ENSMUST00000132608.1	Procr	protein C receptor, endothelial
chr8_+_23411490	0.499	ENSMUST00000033952.7	Sfrp1	secreted frizzled-related protein 1
chr5_+_136987019	0.475	ENSMUST00000004968.4	Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr10_-_62527438	0.474	ENSMUST00000160987.1	Srgn	serglycin
chr11_-_59809774	0.463	ENSMUST00000047706.2 ENSMUST00000102697.3	Flcn	folliculin
chr8_+_85432686	0.442	ENSMUST00000180883.1	1700051O22Rik	RIKEN cDNA 1700051O22 Gene
chr10_+_90071095	0.435	ENSMUST00000183109.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_101378183	0.419	ENSMUST00000084895.5	Arap1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_+_116843278	0.417	ENSMUST00000106370.3	Mettl23	methyltransferase like 23
chr3_-_130730310	0.405	ENSMUST00000062601.7	Rpl34	ribosomal protein L34
chrX_+_136822671	0.400	ENSMUST00000033800.6	Plp1	proteolipid protein (myelin) 1
chr6_-_124779686	0.397	ENSMUST00000147669.1 ENSMUST00000128697.1 ENSMUST00000032218.3 ENSMUST00000112475.2	Lrrc23	leucine rich repeat containing 23
chrM_+_8600	0.395	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr1_+_153899937	0.393	ENSMUST00000086199.5	Glul	glutamate-ammonia ligase (glutamine synthetase)
chr5_-_138272786	0.369	ENSMUST00000161279.1 ENSMUST00000161647.1	Gal3st4	galactose-3-O-sulfotransferase 4
chr14_-_108914237	0.362	ENSMUST00000100322.2	Slitrk1	SLIT and NTRK-like family, member 1
chr15_+_98571004	0.351	ENSMUST00000023728.6	4930415O20Rik	RIKEN cDNA 4930415O20 gene
chr7_+_19368498	0.336	ENSMUST00000132655.1	Ppp1r13l	protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr19_-_3575708	0.315	ENSMUST00000113997.2 ENSMUST00000025846.8 ENSMUST00000172362.1	Ppp6r3	protein phosphatase 6, regulatory subunit 3
chr8_+_83566671	0.285	ENSMUST00000036996.5	Ndufb7	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr18_+_56432116	0.266	ENSMUST00000070166.5	Gramd3	GRAM domain containing 3
chrX_+_136822781	0.260	ENSMUST00000113085.1	Plp1	proteolipid protein (myelin) 1
chr4_-_117682233	0.251	ENSMUST00000102687.3	Dmap1	DNA methyltransferase 1-associated protein 1
chrM_+_7759	0.244	ENSMUST00000082407.1 ENSMUST00000082408.1	mt-Atp8 mt-Atp6	mitochondrially encoded ATP synthase 8 mitochondrially encoded ATP synthase 6
chr6_+_3498382	0.240	ENSMUST00000001412.10 ENSMUST00000170873.3 ENSMUST00000184752.1 ENSMUST00000164052.3	Ccdc132	coiled-coil domain containing 132
chrX_-_101086020	0.236	ENSMUST00000113710.1	Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr8_-_105701077	0.226	ENSMUST00000042608.6	Acd	adrenocortical dysplasia
chrX_+_73757069	0.216	ENSMUST00000002079.6	Plxnb3	plexin B3
chr6_+_29853746	0.189	ENSMUST00000064872.6 ENSMUST00000152581.1 ENSMUST00000176265.1 ENSMUST00000154079.1	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2
chr19_+_53140430	0.168	ENSMUST00000111741.2	Add3	adducin 3 (gamma)
chr15_-_100424208	0.166	ENSMUST00000154331.1	Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_-_111271568	0.141	ENSMUST00000035079.3	Mlh1	mutL homolog 1 (E. coli)
chr17_-_15566421	0.134	ENSMUST00000178455.1	Gm6686	predicted pseudogene 6686
chr15_-_63997969	0.134	ENSMUST00000164532.1	Fam49b	family with sequence similarity 49, member B
chr2_+_180078623	0.131	ENSMUST00000087563.6	Mtg2	mitochondrial ribosome associated GTPase 2
chr12_-_79296266	0.124	ENSMUST00000021547.6	Zfyve26	zinc finger, FYVE domain containing 26
chr19_-_56822161	0.113	ENSMUST00000118592.1	A630007B06Rik	RIKEN cDNA A630007B06 gene
chr7_+_103550368	0.110	ENSMUST00000106888.1	Olfr613	olfactory receptor 613
chr19_-_56548013	0.106	ENSMUST00000182059.1	Dclre1a	DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chrX_-_143933089	0.104	ENSMUST00000087313.3	Dcx	doublecortin
chrX_-_99470672	0.101	ENSMUST00000113797.3 ENSMUST00000113790.1 ENSMUST00000036354.6 ENSMUST00000167246.1	Pja1	praja1, RING-H2 motif containing
chr13_-_53473074	0.094	ENSMUST00000021922.8	Msx2	msh homeobox 2
chr2_+_3114220	0.087	ENSMUST00000072955.5	Fam171a1	family with sequence similarity 171, member A1
chr10_-_86011833	0.058	ENSMUST00000105304.1 ENSMUST00000061699.5	Bpifc	BPI fold containing family C
chr18_-_36744518	0.057	ENSMUST00000014438.4	Ndufa2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr13_-_67332525	0.052	ENSMUST00000168892.1 ENSMUST00000109735.2	Zfp595	zinc finger protein 595
chr16_+_33251415	0.049	ENSMUST00000023502.4	Snx4	sorting nexin 4
chr8_+_123477859	0.048	ENSMUST00000001520.7	Afg3l1	AFG3(ATPase family gene 3)-like 1 (yeast)
chr2_-_29787622	0.043	ENSMUST00000177467.1 ENSMUST00000113807.3	Trub2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	12.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
2.1	6.4	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
2.0	14.3	GO:0019532	oxalate transport(GO:0019532)
1.3	3.9	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.9	2.8	GO:0001193	maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.9	2.7	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.4	1.7	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4	2.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.3	1.0	GO:0006059	hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.3	1.9	GO:1903056	positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3	1.2	GO:0061743	motor learning(GO:0061743)
0.3	1.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.3	2.4	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3	1.8	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.3	1.1	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
0.3	1.3	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2	0.5	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2	2.3	GO:0046541	saliva secretion(GO:0046541)
0.2	3.7	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2	0.7	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2	2.8	GO:0048240	sperm capacitation(GO:0048240)
0.2	0.5	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	0.5	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.1	0.4	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	1.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	1.2	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	2.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	0.5	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1	1.2	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	0.6	GO:0021993	initiation of neural tube closure(GO:0021993)
0.1	0.7	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1	0.5	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.1	8.0	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.1	1.4	GO:0016486	peptide hormone processing(GO:0016486)
0.1	1.0	GO:0033572	transferrin transport(GO:0033572)
0.1	0.7	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.1	1.2	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.1	0.6	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.1	1.1	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.2	GO:0015819	lysine transport(GO:0015819) ornithine transport(GO:0015822)
0.0	0.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.0	5.4	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.2	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.0	0.4	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.0	0.7	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.0	0.6	GO:0006907	pinocytosis(GO:0006907)
0.0	1.2	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	1.4	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	3.7	GO:0007416	synapse assembly(GO:0007416)
0.0	0.4	GO:0009060	aerobic respiration(GO:0009060)
0.0	1.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	2.6	GO:0016052	carbohydrate catabolic process(GO:0016052)
0.0	0.5	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	4.7	GO:1902593	protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.1	GO:0071953	elastic fiber(GO:0071953)
0.4	1.8	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3	2.4	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	1.0	GO:0097454	Schwann cell microvillus(GO:0097454)
0.2	0.7	GO:0098835	presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2	1.2	GO:1990131	Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2	1.3	GO:0097443	sorting endosome(GO:0097443)
0.1	2.8	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	1.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	1.8	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	33.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	3.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	1.1	GO:0005688	U6 snRNP(GO:0005688)
0.1	0.6	GO:0005638	lamin filament(GO:0005638)
0.1	6.4	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.5	GO:0042629	mast cell granule(GO:0042629)
0.1	2.8	GO:0031672	A band(GO:0031672)
0.0	4.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.4	GO:0097386	glial cell projection(GO:0097386)
0.0	1.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	2.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.6	GO:0044295	axonal growth cone(GO:0044295)
0.0	1.8	GO:0001650	fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.4	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
2.1	12.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
1.3	14.3	GO:0019531	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.9	2.7	GO:0004962	endothelin receptor activity(GO:0004962)
0.9	2.6	GO:0016160	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.6	3.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4	1.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.4	2.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.4	1.1	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.3	1.8	GO:0000150	recombinase activity(GO:0000150)
0.2	8.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.2	1.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2	2.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	1.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	1.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	1.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.4	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.1	0.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	4.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	2.7	GO:0042287	MHC protein binding(GO:0042287)
0.1	0.7	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	0.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	1.0	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	2.8	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	0.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.4	GO:0050694	galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	1.9	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.6	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.6	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	1.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.6	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	2.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	1.4	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	2.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	1.1	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.4	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.1	2.5	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	2.7	PID_ARF6_TRAFFICKING_PATHWAY	Arf6 trafficking events
0.0	1.3	PID_CDC42_REG_PATHWAY	Regulation of CDC42 activity
0.0	5.1	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.3	PID_RHOA_REG_PATHWAY	Regulation of RhoA activity
0.0	0.5	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.6	PID_MAPK_TRK_PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.6	PID_NEPHRIN_NEPH1_PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	1.2	PID_MTOR_4PATHWAY	mTOR signaling pathway
0.0	0.5	ST_WNT_BETA_CATENIN_PATHWAY	Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	8.0	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.4	3.9	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.3	27.7	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	2.8	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.2	4.5	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.1	REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.2	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	0.9	REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	2.7	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.1	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.6	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.9	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)

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