Motif ID: Meox2

Z-value: 0.738


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.173.2e-01Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 154 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_42907563 5.529 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_25980039 4.887 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119811 4.774 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26259109 3.589 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr13_+_104229366 3.104 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr17_+_75005523 2.628 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr5_-_62766153 2.288 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_+_59458372 2.224 ENSMUST00000062216.3
 Emx2
empty spiracles homeobox 2
chr3_+_66219909 1.988 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chrM_+_10167 1.901 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr15_-_99651580 1.857 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
 Racgap1




Rac GTPase-activating protein 1




chr10_-_116972609 1.855 ENSMUST00000092165.4
 Gm10271
predicted gene 10271
chr8_+_12395287 1.846 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr15_-_74752963 1.753 ENSMUST00000023259.8
 Lynx1
Ly6/neurotoxin 1
chr8_-_4779513 1.709 ENSMUST00000022945.7
 Shcbp1
Shc SH2-domain binding protein 1
chr9_-_36726374 1.690 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
 Chek1


checkpoint kinase 1


chr6_+_34598500 1.674 ENSMUST00000079391.3
ENSMUST00000142512.1
 Cald1

caldesmon 1

chr14_+_25979401 1.668 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr3_+_127553462 1.528 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chrM_-_14060 1.521 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 5.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 2.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.6 2.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 2.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 2.0 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.6 1.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 1.7 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 1.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 1.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 1.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 1.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 1.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 GO:0070469 respiratory chain(GO:0070469)
0.9 2.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 2.6 GO:0000776 kinetochore(GO:0000776)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.4 1.9 GO:0097149 centralspindlin complex(GO:0097149)
0.2 1.7 GO:0030478 actin cap(GO:0030478)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.1 1.0 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 4.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7 2.6 GO:0050436 microfibril binding(GO:0050436)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.6 1.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.9 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.1 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 2.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.0 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 1.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 1.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation