Motif ID: Mga

Z-value: 0.390


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.343.7e-02Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_65805832 1.799 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr16_-_45844303 1.346 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chrX_+_35888808 1.288 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr8_-_61902669 0.953 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr3_+_76075583 0.852 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr7_+_27486910 0.827 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr13_-_8870967 0.794 ENSMUST00000164183.2
Wdr37
WD repeat domain 37
chr5_+_137745730 0.737 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr2_-_170131156 0.676 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr11_+_113657375 0.655 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
Cog1


component of oligomeric golgi complex 1


chr5_-_124352233 0.608 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_-_3931960 0.591 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr11_+_49203465 0.580 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr11_+_49203285 0.562 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr1_+_171419027 0.540 ENSMUST00000171362.1
Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr7_-_3720382 0.533 ENSMUST00000078451.6
Pirb
paired Ig-like receptor B
chr11_+_77515104 0.471 ENSMUST00000094004.4
Abhd15
abhydrolase domain containing 15
chr13_-_74482943 0.466 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr5_-_86676346 0.462 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr7_+_13278778 0.454 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr6_-_41636389 0.452 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr2_+_144527718 0.452 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr13_-_8870999 0.448 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
Wdr37


WD repeat domain 37


chr5_-_115134907 0.430 ENSMUST00000060798.5
Unc119b
unc-119 homolog B (C. elegans)
chr17_+_35861318 0.390 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr4_+_62525369 0.361 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr17_+_26252903 0.358 ENSMUST00000025023.7
Luc7l
Luc7 homolog (S. cerevisiae)-like
chr5_-_138619702 0.343 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr5_-_138619751 0.340 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr15_+_51877429 0.332 ENSMUST00000137116.2
ENSMUST00000161651.1
ENSMUST00000059599.9
Utp23


UTP23, small subunit (SSU) processome component, homolog (yeast)


chr3_+_124321031 0.312 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr9_-_85749308 0.308 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr4_-_132732514 0.305 ENSMUST00000045550.4
Xkr8
X Kell blood group precursor related family member 8 homolog
chr5_+_149265035 0.303 ENSMUST00000130144.1
ENSMUST00000071130.3
Alox5ap

arachidonate 5-lipoxygenase activating protein

chr5_+_100196611 0.289 ENSMUST00000066813.1
Gm9932
predicted gene 9932
chr10_+_18055711 0.271 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
Reps1



RalBP1 associated Eps domain containing protein



chr8_+_3353415 0.251 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr7_+_48789003 0.250 ENSMUST00000118927.1
ENSMUST00000125280.1
Zdhhc13

zinc finger, DHHC domain containing 13

chr4_-_117125618 0.230 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr15_+_51877742 0.227 ENSMUST00000136129.1
Utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr6_+_3993776 0.217 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr5_-_138619653 0.211 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chrX_+_163909132 0.211 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr1_+_170214826 0.210 ENSMUST00000159201.1
ENSMUST00000055830.1
4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr4_-_41314877 0.210 ENSMUST00000030145.8
Dcaf12
DDB1 and CUL4 associated factor 12
chr7_-_30880263 0.204 ENSMUST00000108125.2
Cd22
CD22 antigen
chr15_-_43869993 0.198 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr9_-_96478660 0.193 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr2_+_55411790 0.193 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr12_+_84316830 0.185 ENSMUST00000045931.10
Zfp410
zinc finger protein 410
chr11_-_78751656 0.183 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr9_-_96478596 0.179 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr9_+_59291565 0.179 ENSMUST00000026266.7
Adpgk
ADP-dependent glucokinase
chr3_-_146521396 0.177 ENSMUST00000029838.6
Rpf1
ribosome production factor 1 homolog (S. cerevisiae)
chr9_-_117252450 0.168 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr16_-_59639124 0.161 ENSMUST00000149797.1
ENSMUST00000023405.9
Arl6

ADP-ribosylation factor-like 6

chr5_-_120777628 0.157 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr2_+_83644435 0.156 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr13_-_23313400 0.145 ENSMUST00000155432.1
4930557F10Rik
RIKEN cDNA 4930557F10 gene
chr14_+_64652524 0.137 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr19_-_40588374 0.131 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chrY_-_6681243 0.117 ENSMUST00000115940.1
Gm21719
predicted gene, 21719
chr8_+_3393018 0.109 ENSMUST00000004684.6
ENSMUST00000145394.1
Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chrX_+_20617503 0.089 ENSMUST00000115375.1
ENSMUST00000115374.1
ENSMUST00000084383.3
Rbm10


RNA binding motif protein 10


chr7_+_24081888 0.077 ENSMUST00000068975.3
Zfp180
zinc finger protein 180
chr1_+_190928822 0.071 ENSMUST00000135364.1
Angel2
angel homolog 2 (Drosophila)
chr17_+_34305883 0.069 ENSMUST00000074557.8
H2-Eb1
histocompatibility 2, class II antigen E beta
chr6_+_5390387 0.064 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr12_-_54695885 0.048 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr12_-_54695813 0.038 ENSMUST00000110713.3
Eapp
E2F-associated phosphoprotein
chr10_+_75212065 0.026 ENSMUST00000105421.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr3_+_89773562 0.023 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr18_+_20944607 0.014 ENSMUST00000050004.1
Rnf125
ring finger protein 125
chr6_-_149188648 0.012 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
Amn1


antagonist of mitotic exit network 1


chr10_+_115384951 0.011 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr8_-_13974715 0.001 ENSMUST00000119182.1
ENSMUST00000062613.4
Tdrp

testis development related protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.0 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.0 1.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.0 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.8 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.5 PID_BCR_5PATHWAY BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression