Motif ID: Mga

Z-value: 0.390


Transcription factors associated with Mga:

Gene SymbolEntrez IDGene Name
Mga ENSMUSG00000033943.9 Mga

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_1198973050.343.7e-02Click!


Activity profile for motif Mga.

activity profile for motif Mga


Sorted Z-values histogram for motif Mga

Sorted Z-values for motif Mga



Network of associatons between targets according to the STRING database.



First level regulatory network of Mga

PNG image of the network

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Top targets:


Showing 1 to 20 of 76 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65805832 1.799 ENSMUST00000022612.3
 Pbk
PDZ binding kinase
chr16_-_45844303 1.346 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chrX_+_35888808 1.288 ENSMUST00000033419.6
 Dock11
dedicator of cytokinesis 11
chr8_-_61902669 0.953 ENSMUST00000121785.1
ENSMUST00000034057.7
 Palld

palladin, cytoskeletal associated protein

chr3_+_76075583 0.852 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr7_+_27486910 0.827 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chr13_-_8870967 0.794 ENSMUST00000164183.2
 Wdr37
WD repeat domain 37
chr5_+_137745730 0.737 ENSMUST00000100540.3
 Tsc22d4
TSC22 domain family, member 4
chr2_-_170131156 0.676 ENSMUST00000063710.6
 Zfp217
zinc finger protein 217
chr11_+_113657375 0.655 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
 Cog1


component of oligomeric golgi complex 1


chr5_-_124352233 0.608 ENSMUST00000111472.1
 Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_-_3931960 0.591 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
 Tcn2




transcobalamin 2




chr11_+_49203465 0.580 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr11_+_49203285 0.562 ENSMUST00000109198.1
ENSMUST00000137061.2
 Zfp62

zinc finger protein 62

chr1_+_171419027 0.540 ENSMUST00000171362.1
 Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr7_-_3720382 0.533 ENSMUST00000078451.6
 Pirb
paired Ig-like receptor B
chr11_+_77515104 0.471 ENSMUST00000094004.4
 Abhd15
abhydrolase domain containing 15
chr13_-_74482943 0.466 ENSMUST00000074369.6
 Zfp825
zinc finger protein 825
chr5_-_86676346 0.462 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr7_+_13278778 0.454 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
 Lig1


ligase I, DNA, ATP-dependent



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 1.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.0 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.6 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.5 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression