Motif ID: Mnt

Z-value: 0.621


Transcription factors associated with Mnt:

Gene SymbolEntrez IDGene Name
Mnt ENSMUSG00000000282.6 Mnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mntmm10_v2_chr11_+_74830920_74831005-0.315.8e-02Click!


Activity profile for motif Mnt.

activity profile for motif Mnt


Sorted Z-values histogram for motif Mnt

Sorted Z-values for motif Mnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Mnt

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_25570678 2.931 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr6_+_17463749 2.453 ENSMUST00000115443.1
 Met
met proto-oncogene
chr2_+_4300462 2.402 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr11_-_101785252 2.365 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chrX_-_51681703 2.360 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr16_-_43979050 2.329 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr12_+_70825492 2.283 ENSMUST00000057859.7
 Frmd6
FERM domain containing 6
chr9_-_121495678 2.241 ENSMUST00000035120.4
 Cck
cholecystokinin
chr6_+_17463927 2.198 ENSMUST00000115442.1
 Met
met proto-oncogene
chr15_+_81811414 2.149 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr3_-_89773221 2.131 ENSMUST00000038450.1
 4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr1_-_186705980 2.031 ENSMUST00000045288.8
 Tgfb2
transforming growth factor, beta 2
chr13_-_92131494 1.861 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr6_+_108660616 1.812 ENSMUST00000032194.4
 Bhlhe40
basic helix-loop-helix family, member e40
chr12_+_24651346 1.718 ENSMUST00000020982.5
 Klf11
Kruppel-like factor 11
chr8_+_84990585 1.697 ENSMUST00000064495.6
 Hook2
hook homolog 2 (Drosophila)
chr17_-_66077022 1.693 ENSMUST00000150766.1
ENSMUST00000038116.5
 Ankrd12

ankyrin repeat domain 12

chr6_+_17463826 1.666 ENSMUST00000140070.1
 Met
met proto-oncogene
chr12_-_90738438 1.602 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr17_-_26201363 1.576 ENSMUST00000121959.1
 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 246 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 6.8 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 3.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 3.4 GO:0008643 carbohydrate transport(GO:0008643)
1.0 2.9 GO:0072034 renal vesicle induction(GO:0072034)
0.8 2.4 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.4 2.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.4 2.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 2.3 GO:0003383 apical constriction(GO:0003383)
0.2 2.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 2.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.7 2.1 GO:0043379 memory T cell differentiation(GO:0043379)
0.2 2.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.1 GO:0018345 protein palmitoylation(GO:0018345)
0.5 2.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 2.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.6 1.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 1.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.4 1.7 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.3 1.7 GO:0055091 phospholipid homeostasis(GO:0055091)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.9 GO:0030686 90S preribosome(GO:0030686)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 2.2 GO:0043203 axon hillock(GO:0043203)
0.1 2.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.4 1.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 1.9 GO:0030426 growth cone(GO:0030426)
0.6 1.7 GO:0000802 transverse filament(GO:0000802)
0.2 1.7 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0014704 intercalated disc(GO:0014704)
0.4 1.5 GO:0043511 inhibin complex(GO:0043511)
0.1 1.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.3 1.4 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.3 1.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)
0.1 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 153 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 6.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 4.0 GO:0015485 cholesterol binding(GO:0015485)
0.2 3.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 3.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 2.9 GO:0043426 MRF binding(GO:0043426)
0.4 2.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 2.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 2.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 1.5 GO:0034711 inhibin binding(GO:0034711)
0.1 1.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.2 PID_ARF6_PATHWAY Arf6 signaling events
0.2 3.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.8 PID_FOXO_PATHWAY FoxO family signaling
0.2 3.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 3.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.7 PID_LKB1_PATHWAY LKB1 signaling events
0.1 2.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 2.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.1 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 0.8 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.6 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 3.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 2.7 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 2.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.9 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.6 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.4 1.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 1.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.2 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 1.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.1 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)