Motif ID: Mnx1_Lhx6_Lmx1a

Z-value: 0.881

Transcription factors associated with Mnx1_Lhx6_Lmx1a:

Gene SymbolEntrez IDGene Name
Lhx6 ENSMUSG00000026890.13 Lhx6
Lmx1a ENSMUSG00000026686.8 Lmx1a
Mnx1 ENSMUSG00000001566.8 Mnx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lmx1amm10_v2_chr1_+_167689108_1676892390.724.6e-07Click!
Lhx6mm10_v2_chr2_-_36105271_36105434-0.529.8e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Mnx1_Lhx6_Lmx1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_61902669 10.871 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr5_+_139543889 9.496 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr5_-_62766153 8.957 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_55782500 6.637 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr15_+_25773985 5.992 ENSMUST00000125667.1
Myo10
myosin X
chr9_+_118478182 5.513 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_65890237 5.398 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr9_+_118478344 5.328 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_+_25372315 4.900 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr2_+_20737306 4.725 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr4_-_97778042 3.933 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_-_172027269 3.878 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr8_+_45658666 3.798 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr13_-_97747373 3.766 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr8_+_45658731 3.658 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_-_72986716 3.613 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr3_-_88410295 3.517 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr7_-_49636847 3.510 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr11_-_3931960 3.498 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr5_+_92809372 3.472 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr9_+_96258697 3.447 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr13_-_97747399 3.310 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_+_8948608 3.093 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr11_-_3931789 2.961 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr7_-_37773555 2.954 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr14_-_118052235 2.917 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr7_-_116031047 2.824 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr2_-_116067391 2.818 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr19_+_59458372 2.715 ENSMUST00000062216.3
Emx2
empty spiracles homeobox 2
chr16_+_33684538 2.628 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr18_+_57468478 2.540 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr4_-_45532470 2.394 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr6_-_147264124 2.378 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr7_-_37769624 2.351 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr1_-_172027251 2.324 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr2_+_116067213 2.297 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr8_-_84662841 2.296 ENSMUST00000060427.4
Ier2
immediate early response 2
chr2_-_18048784 2.290 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr4_+_97777780 2.212 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr16_+_43503607 2.201 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr6_+_15196949 2.195 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr7_-_37772868 2.123 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chrM_+_2743 2.027 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr6_+_138140521 2.019 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chrX_-_60893430 1.965 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_110292719 1.961 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_+_26772477 1.950 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr7_-_101837776 1.947 ENSMUST00000165052.1
Inppl1
inositol polyphosphate phosphatase-like 1
chr14_-_48665098 1.942 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_92683625 1.926 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr3_-_86548268 1.919 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr1_-_55226768 1.901 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr1_+_82233112 1.777 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr2_+_181767283 1.755 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr6_+_138140298 1.751 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr12_+_38780284 1.736 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_181767040 1.736 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr6_+_34746368 1.704 ENSMUST00000142716.1
Cald1
caldesmon 1
chr6_+_7555053 1.663 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chrX_+_134308084 1.645 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr9_+_89199319 1.642 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr4_-_110287479 1.568 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr5_+_64812336 1.554 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_+_109983737 1.532 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr7_+_29071597 1.516 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr15_+_55307743 1.499 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr11_+_60537978 1.498 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr2_+_119047129 1.482 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr4_-_155056784 1.446 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr17_+_36958571 1.444 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr17_+_36958623 1.424 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr3_+_94372794 1.406 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr17_-_70853482 1.403 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr9_+_119063429 1.388 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr7_-_73541738 1.388 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr3_-_66296807 1.366 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr2_-_168767136 1.356 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr3_+_125404072 1.344 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr2_-_28916412 1.310 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr5_+_138187485 1.288 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr10_+_88091070 1.280 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr19_+_44493472 1.267 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr10_+_37139558 1.252 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chrM_+_10167 1.232 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr9_-_52168111 1.229 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr14_+_79515618 1.218 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr3_+_40800778 1.216 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr12_+_38783503 1.216 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr17_-_48432723 1.212 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_+_23069210 1.199 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chrM_+_7005 1.193 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr8_-_31918203 1.166 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr12_+_38780817 1.149 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr11_+_101582236 1.137 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A



chrM_+_9870 1.109 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr17_+_34592248 1.083 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr3_-_157925056 1.053 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr8_-_26119125 1.031 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr3_+_125404292 0.993 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr10_-_6980376 0.985 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chrX_-_102157065 0.958 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr3_+_76593550 0.950 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr12_-_54986328 0.946 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chrX_+_9885622 0.942 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr13_-_89742244 0.931 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr12_-_54986363 0.926 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chrM_+_9452 0.925 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr3_-_87174657 0.920 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr16_-_63864114 0.896 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr3_+_32436151 0.872 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_+_156035392 0.865 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr17_+_45734506 0.838 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chrX_-_155216338 0.838 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr7_-_5014645 0.827 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr1_+_110099295 0.820 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr11_-_87108656 0.816 ENSMUST00000051395.8
Prr11
proline rich 11
chrM_-_14060 0.800 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr14_-_48662740 0.786 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr14_+_25980039 0.784 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr6_-_57535422 0.773 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr2_-_168767029 0.757 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr16_-_45724600 0.752 ENSMUST00000096057.4
Tagln3
transgelin 3
chr10_-_8886033 0.743 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr19_+_55895508 0.740 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_-_90716489 0.736 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1
chrX_+_169685191 0.731 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr16_+_42907563 0.719 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr15_-_50889691 0.703 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr2_-_28916668 0.696 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chrM_+_11734 0.684 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr12_-_111813834 0.678 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chrX_-_74246534 0.667 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr1_-_163725123 0.664 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr1_-_24612700 0.647 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr12_+_55598917 0.647 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr5_+_9100681 0.647 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr12_+_38781093 0.645 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr1_-_156034800 0.642 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr2_+_22622183 0.631 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr13_+_23575753 0.621 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chrX_+_103356464 0.616 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr7_-_46667375 0.609 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr6_+_11926758 0.597 ENSMUST00000133776.1
Phf14
PHD finger protein 14
chr18_-_54990124 0.591 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr12_+_3954943 0.586 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr13_-_78196373 0.585 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr2_+_125068118 0.576 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr15_-_9140374 0.575 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chrX_+_166344692 0.564 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr12_+_51348370 0.557 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr4_+_140701466 0.555 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2

regulator of chromosome condensation 2

chr12_+_51348019 0.554 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr2_-_60963192 0.549 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr9_+_72806874 0.547 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr12_+_51348265 0.538 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr19_-_50678642 0.510 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr12_+_52699297 0.500 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_132247747 0.499 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr16_+_43235856 0.498 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr7_+_25681158 0.491 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr3_+_32436376 0.489 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_+_37208291 0.487 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr5_+_13398688 0.468 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_+_43364145 0.456 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr5_+_135994796 0.450 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr10_-_37138863 0.446 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr18_-_44662251 0.442 ENSMUST00000164666.1
Mcc
mutated in colorectal cancers
chr3_+_159839729 0.439 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr13_-_83729544 0.431 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr1_-_156034826 0.425 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1

torsin A interacting protein 1

chrM_+_14138 0.424 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr1_-_75046639 0.415 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr4_-_132075250 0.415 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr17_+_73107982 0.412 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr1_+_10993452 0.409 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr3_-_116712644 0.400 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr3_+_134236483 0.400 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chrX_-_74246364 0.397 ENSMUST00000130007.1
Flna
filamin, alpha
chr16_+_43363855 0.396 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_-_150589844 0.394 ENSMUST00000112725.1
ENSMUST00000112720.1
Apex2

apurinic/apyrimidinic endonuclease 2

chr5_+_135106881 0.390 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr2_-_170194033 0.383 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr5_-_31526693 0.382 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr8_-_67818284 0.355 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_69897220 0.352 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr3_+_90062781 0.352 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr5_-_84417359 0.350 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr19_+_24875679 0.346 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr1_+_153665627 0.341 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr3_-_33082004 0.332 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr9_-_50728067 0.328 ENSMUST00000117646.1
Dixdc1
DIX domain containing 1
chr1_-_183147461 0.321 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr5_+_121749196 0.318 ENSMUST00000161064.1
Atxn2
ataxin 2
chr14_+_54894573 0.316 ENSMUST00000141446.1
ENSMUST00000139985.1
ENSMUST00000172557.1
Pabpn1


poly(A) binding protein, nuclear 1


chr12_+_72441933 0.315 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr16_+_19760232 0.313 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr18_-_75697639 0.312 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr8_+_23669653 0.308 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr6_+_40471352 0.303 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1




single-stranded DNA binding protein 1




chr2_-_129699833 0.300 ENSMUST00000028883.5
Pdyn
prodynorphin

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.1 6.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.6 6.5 GO:0015889 cobalamin transport(GO:0015889)
1.2 9.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.9 3.8 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.9 2.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.7 2.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.7 2.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.6 10.9 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.6 8.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 2.9 GO:0006570 tyrosine metabolic process(GO:0006570)
0.5 1.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 4.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 1.3 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.4 1.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 2.4 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.4 1.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.4 1.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 1.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 3.8 GO:0060539 diaphragm development(GO:0060539)
0.3 2.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 0.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 0.8 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.9 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.3 2.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 2.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 1.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.6 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 9.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 3.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 1.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.2 1.2 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.2 0.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.2 GO:0030242 pexophagy(GO:0030242)
0.2 1.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 2.2 GO:0072189 ureter development(GO:0072189)
0.2 0.5 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.6 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 1.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 2.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 4.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 2.0 GO:0007530 sex determination(GO:0007530)
0.1 0.6 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.4 GO:0033762 response to glucagon(GO:0033762)
0.1 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 4.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 1.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 2.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.1 0.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) dopamine catabolic process(GO:0042420) catecholamine catabolic process(GO:0042424)
0.1 0.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 3.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.3 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 1.4 GO:0051693 actin filament capping(GO:0051693)
0.1 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.6 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 1.7 GO:0030901 midbrain development(GO:0030901)
0.0 3.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 2.3 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.9 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.9 GO:0007588 excretion(GO:0007588)
0.0 1.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.6 GO:0001824 blastocyst development(GO:0001824)
0.0 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.5 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0060948 zygotic specification of dorsal/ventral axis(GO:0007352) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 1.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0060187 cell pole(GO:0060187)
0.6 3.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 1.9 GO:0008623 CHRAC(GO:0008623)
0.5 1.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 10.9 GO:0002102 podosome(GO:0002102)
0.2 3.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.7 GO:0030478 actin cap(GO:0030478)
0.2 1.1 GO:0031523 Myb complex(GO:0031523)
0.2 1.2 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 6.0 GO:0016459 myosin complex(GO:0016459)
0.1 8.3 GO:0070469 respiratory chain(GO:0070469)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 3.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 4.9 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.2 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0043679 axon terminus(GO:0043679)
0.0 1.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.5 GO:0031419 cobalamin binding(GO:0031419)
0.5 8.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.4 1.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.4 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 3.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 0.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 1.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 6.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 2.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 10.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.6 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 0.6 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 2.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 10.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 3.8 GO:1900750 glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.4 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 3.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.6 GO:0005542 folic acid binding(GO:0005542)
0.1 0.7 GO:0000150 recombinase activity(GO:0000150)
0.1 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 6.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.1 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.1 9.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 6.1 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 2.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 6.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 13.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 8.5 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.2 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.5 PID_ARF6_PATHWAY Arf6 signaling events
0.2 10.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 4.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 0.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID_MYC_PATHWAY C-MYC pathway
0.0 4.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.6 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 6.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 8.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.2 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 8.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 1.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 1.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels