ISMARA results: Msx3

Motif ID: Msx3

Z-value: 0.425

Transcription factors associated with Msx3:

Gene Symbol	Entrez ID	Gene Name
Msx3	ENSMUSG00000025469.9	Msx3

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Msx3	mm10_v2_chr7_-_140049140_140049180	0.61	6.0e-05	Click!

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Showing 1 to 20 of 65 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_14621805	3.442	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr4_-_14621669	2.009	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr4_-_14621494	1.993	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr15_+_44787746	1.937	ENSMUST00000181839.1	2310069G16Rik	RIKEN cDNA 2310069G16 gene
chr4_+_102254739	1.695	ENSMUST00000106907.2	Pde4b	phosphodiesterase 4B, cAMP specific
chr10_+_81257277	1.522	ENSMUST00000117488.1 ENSMUST00000105328.3 ENSMUST00000121205.1	Matk	megakaryocyte-associated tyrosine kinase
chr9_-_53975246	1.186	ENSMUST00000048409.7	Elmod1	ELMO/CED-12 domain containing 1
chr2_-_45117349	1.159	ENSMUST00000176438.2	Zeb2	zinc finger E-box binding homeobox 2
chr2_-_33087169	1.138	ENSMUST00000102810.3	Garnl3	GTPase activating RANGAP domain-like 3
chr2_+_125136692	1.046	ENSMUST00000099452.2	Ctxn2	cortexin 2
chr2_-_33086366	1.027	ENSMUST00000049618.2	Garnl3	GTPase activating RANGAP domain-like 3
chr10_+_39612934	0.994	ENSMUST00000019987.6	Traf3ip2	TRAF3 interacting protein 2
chr3_-_116253467	0.889	ENSMUST00000090473.5	Gpr88	G-protein coupled receptor 88
chr10_+_88379217	0.840	ENSMUST00000130301.1 ENSMUST00000020251.8	Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr7_-_127895578	0.819	ENSMUST00000033074.6	Vkorc1	vitamin K epoxide reductase complex, subunit 1
chr15_+_82252397	0.794	ENSMUST00000136948.1	1500009C09Rik	RIKEN cDNA 1500009C09 gene
chr10_+_88379127	0.733	ENSMUST00000127615.1	Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr4_+_94739276	0.650	ENSMUST00000073939.6 ENSMUST00000102798.1	Tek	endothelial-specific receptor tyrosine kinase
chr17_-_24527830	0.534	ENSMUST00000176353.1 ENSMUST00000176237.1	Traf7	TNF receptor-associated factor 7
chr12_+_102128718	0.525	ENSMUST00000159329.1	Slc24a4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 24 entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	7.4	GO:0019532	oxalate transport(GO:0019532)
0.1	1.7	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5	1.6	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.0	1.5	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2	1.2	GO:1903056	positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0	1.2	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1	1.0	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	1.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.2	0.9	GO:0061743	motor learning(GO:0061743)
0.3	0.8	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2	0.6	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.5	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.5	GO:0097186	amelogenesis(GO:0097186)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.1	0.4	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.4	GO:0042701	progesterone secretion(GO:0042701)
0.0	0.4	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.4	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0	0.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.3	GO:0009838	abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)

Gene overrepresentation in cellular_component category:

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Showing 1 to 12 of 12 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.3	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	1.7	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	1.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	0.5	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.3	GO:0099569	presynaptic cytoskeleton(GO:0099569)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.3	GO:0090543	ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular_function category:

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Showing 1 to 13 of 13 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	7.4	GO:0019531	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1	1.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4	1.6	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	1.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	1.2	GO:0070412	R-SMAD binding(GO:0070412)
0.1	0.8	GO:0048038	quinone binding(GO:0048038)
0.1	0.5	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.4	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	0.4	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	0.3	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)

Gene overrepresentation in C2:CP category:

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Showing 1 to 3 of 3 entries

Total log-likelihood	Term	Description
1.5	PID_KIT_PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6	PID_SHP2_PATHWAY	SHP2 signaling
0.4	ST_GA12_PATHWAY	G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 10 of 10 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.0	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.7	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.0	1.5	REACTOME_SIGNALING_BY_ERBB2	Genes involved in Signaling by ERBB2
0.1	0.8	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.6	REACTOME_TIE2_SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME_GLUCOSE_TRANSPORT	Genes involved in Glucose transport
0.0	0.3	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES	Genes involved in The activation of arylsulfatases