Motif ID: Mybl1
Z-value: 0.908
Transcription factors associated with Mybl1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mybl1 | ENSMUSG00000025912.10 | Mybl1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mybl1 | mm10_v2_chr1_-_9700209_9700329 | 0.04 | 7.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.5 | GO:0003360 | brainstem development(GO:0003360) |
0.8 | 4.8 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.4 | 6.6 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.4 | 1.1 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.4 | 1.1 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.3 | 1.6 | GO:0015671 | oxygen transport(GO:0015671) |
0.3 | 2.2 | GO:0000279 | M phase(GO:0000279) |
0.3 | 2.9 | GO:0071493 | cellular response to UV-B(GO:0071493) |
0.3 | 1.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.3 | 1.2 | GO:0061055 | myotome development(GO:0061055) |
0.3 | 3.3 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.3 | 1.3 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.3 | 1.8 | GO:0035701 | hematopoietic stem cell migration(GO:0035701) |
0.2 | 0.7 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.2 | 1.2 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
0.2 | 1.8 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
0.2 | 5.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.2 | 0.9 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
0.2 | 1.0 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
0.2 | 0.6 | GO:0006097 | glyoxylate cycle(GO:0006097) |
0.2 | 0.6 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.2 | 0.6 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.2 | 0.9 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
0.2 | 0.5 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
0.2 | 0.9 | GO:0019659 | fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.2 | 1.4 | GO:0070474 | positive regulation of uterine smooth muscle contraction(GO:0070474) |
0.2 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.2 | 0.5 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313) |
0.2 | 0.5 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.2 | 0.5 | GO:1902174 | striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.2 | 0.7 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.2 | 0.5 | GO:0046671 | negative regulation of retinal cell programmed cell death(GO:0046671) |
0.2 | 0.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.1 | 0.9 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 0.7 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
0.1 | 0.7 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.1 | 0.7 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
0.1 | 0.7 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 0.8 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.1 | 0.4 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.1 | 0.4 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 0.6 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.1 | 0.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.1 | 0.4 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
0.1 | 0.4 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.1 | 1.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.1 | 0.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.1 | 0.7 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
0.1 | 0.5 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
0.1 | 0.6 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
0.1 | 0.4 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 0.6 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
0.1 | 1.0 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.1 | 0.4 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 0.6 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
0.1 | 1.6 | GO:0051451 | myoblast migration(GO:0051451) |
0.1 | 0.3 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
0.1 | 0.3 | GO:0071609 | chemokine (C-C motif) ligand 5 production(GO:0071609) |
0.1 | 1.6 | GO:0043248 | proteasome assembly(GO:0043248) |
0.1 | 0.2 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
0.1 | 0.4 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
0.1 | 0.3 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.1 | 0.3 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.1 | 0.5 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.1 | 0.5 | GO:1901526 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
0.1 | 0.9 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.1 | 0.5 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.4 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
0.1 | 0.3 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.1 | 0.3 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
0.1 | 2.9 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.1 | 1.5 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
0.1 | 0.3 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.1 | 0.2 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.1 | 0.2 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.1 | 0.5 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 0.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.1 | 0.3 | GO:0030091 | protein repair(GO:0030091) |
0.1 | 0.4 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
0.1 | 0.5 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.1 | 0.3 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
0.1 | 2.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 0.6 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.1 | 0.6 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.1 | 1.0 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.1 | 0.3 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
0.1 | 0.8 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.1 | 0.3 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.1 | 0.3 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 0.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.5 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.1 | 0.4 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 0.2 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
0.1 | 0.3 | GO:0018201 | peptidyl-glycine modification(GO:0018201) |
0.1 | 0.2 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.1 | 0.7 | GO:0060347 | heart trabecula formation(GO:0060347) amyloid fibril formation(GO:1990000) |
0.1 | 0.7 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 0.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 1.4 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.1 | 0.4 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.1 | 0.3 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
0.1 | 0.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.1 | 0.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.1 | 3.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.1 | 0.4 | GO:0042126 | nitrate metabolic process(GO:0042126) |
0.1 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.1 | 0.1 | GO:0032714 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) negative regulation of interleukin-5 production(GO:0032714) |
0.1 | 0.4 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.3 | GO:0002155 | regulation of thyroid hormone mediated signaling pathway(GO:0002155) |
0.1 | 1.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.1 | 0.3 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
0.1 | 0.2 | GO:0046037 | GMP metabolic process(GO:0046037) |
0.1 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 0.7 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
0.1 | 0.7 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.1 | 2.9 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.1 | 0.2 | GO:0035937 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
0.1 | 0.3 | GO:0086028 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
0.0 | 0.2 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
0.0 | 0.5 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.4 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 0.3 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.0 | 0.2 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
0.0 | 1.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.6 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.7 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
0.0 | 0.2 | GO:0015870 | acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374) |
0.0 | 0.1 | GO:0006272 | leading strand elongation(GO:0006272) DNA replication proofreading(GO:0045004) |
0.0 | 0.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.2 | GO:1902036 | hematopoietic stem cell differentiation(GO:0060218) regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.0 | 1.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.2 | GO:0046967 | cytosol to ER transport(GO:0046967) |
0.0 | 0.4 | GO:1901070 | GTP biosynthetic process(GO:0006183) guanosine-containing compound biosynthetic process(GO:1901070) |
0.0 | 0.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.2 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.0 | 0.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 0.2 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.0 | 0.8 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.3 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
0.0 | 0.1 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.0 | 0.3 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
0.0 | 0.1 | GO:0019405 | hexitol metabolic process(GO:0006059) alditol catabolic process(GO:0019405) fructose biosynthetic process(GO:0046370) |
0.0 | 0.4 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.2 | GO:0019346 | homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) |
0.0 | 0.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
0.0 | 0.1 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
0.0 | 0.3 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
0.0 | 0.3 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.0 | 0.5 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.2 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
0.0 | 0.1 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
0.0 | 0.2 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 1.1 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.3 | GO:0070842 | aggresome assembly(GO:0070842) |
0.0 | 0.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.0 | 1.2 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.0 | 0.4 | GO:0032366 | intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367) |
0.0 | 1.4 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.0 | 0.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.3 | GO:0070836 | caveola assembly(GO:0070836) |
0.0 | 0.3 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.0 | 0.1 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.0 | 0.5 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.0 | 0.3 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 1.5 | GO:0033108 | mitochondrial respiratory chain complex assembly(GO:0033108) |
0.0 | 0.2 | GO:0002689 | negative regulation of leukocyte chemotaxis(GO:0002689) |
0.0 | 0.3 | GO:0008637 | apoptotic mitochondrial changes(GO:0008637) |
0.0 | 0.4 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
0.0 | 0.2 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.0 | 0.4 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.0 | 0.3 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.0 | 0.1 | GO:0006868 | glutamine transport(GO:0006868) |
0.0 | 2.0 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.4 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.3 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.0 | 0.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.1 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.0 | 0.2 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.0 | 0.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.1 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
0.0 | 0.1 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.0 | 0.1 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
0.0 | 0.5 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.2 | GO:0046929 | negative regulation of neurotransmitter secretion(GO:0046929) |
0.0 | 0.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 1.2 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
0.0 | 0.3 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
0.0 | 0.2 | GO:0006465 | signal peptide processing(GO:0006465) |
0.0 | 0.3 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.5 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.0 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
0.0 | 0.7 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 0.2 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
0.0 | 0.6 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 0.0 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.0 | 0.1 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 0.3 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.2 | GO:0021924 | cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) |
0.0 | 0.4 | GO:0010470 | regulation of gastrulation(GO:0010470) |
0.0 | 0.1 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.0 | 0.3 | GO:0051352 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) |
0.0 | 0.1 | GO:0034227 | tRNA thio-modification(GO:0034227) |
0.0 | 0.2 | GO:0017144 | drug metabolic process(GO:0017144) |
0.0 | 0.2 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.0 | 0.1 | GO:0006534 | cysteine metabolic process(GO:0006534) |
0.0 | 0.1 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
0.0 | 1.5 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 0.1 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
0.0 | 0.7 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 0.0 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045) |
0.0 | 0.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
0.0 | 0.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.0 | 0.1 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
0.0 | 0.1 | GO:1901911 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.3 | GO:0061512 | protein localization to cilium(GO:0061512) |
0.0 | 0.2 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
0.0 | 0.0 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
1.0 | 3.0 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.4 | 4.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.4 | 1.1 | GO:1990423 | RZZ complex(GO:1990423) |
0.3 | 0.9 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
0.2 | 0.7 | GO:1990047 | spindle matrix(GO:1990047) |
0.2 | 8.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.2 | 1.1 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.2 | 0.7 | GO:1990032 | parallel fiber(GO:1990032) |
0.2 | 1.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.2 | 0.8 | GO:0031523 | Myb complex(GO:0031523) |
0.2 | 1.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 0.6 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.1 | 0.8 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.1 | 3.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 0.4 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
0.1 | 0.5 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 0.8 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.1 | 0.5 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.1 | 0.5 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.1 | 1.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 0.3 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.1 | 0.3 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.1 | 0.3 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.1 | 0.6 | GO:0097255 | R2TP complex(GO:0097255) |
0.1 | 0.3 | GO:0035061 | interchromatin granule(GO:0035061) |
0.1 | 0.5 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.1 | 2.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 0.3 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.1 | 1.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.1 | 0.7 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.6 | GO:0097413 | Lewy body(GO:0097413) |
0.1 | 0.3 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.1 | 0.3 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 1.6 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 3.8 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 0.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.1 | 1.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 0.2 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
0.1 | 0.6 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 0.3 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
0.1 | 4.5 | GO:0005643 | nuclear pore(GO:0005643) |
0.1 | 0.5 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.6 | GO:0031931 | TORC1 complex(GO:0031931) |
0.1 | 1.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.7 | GO:0000974 | Prp19 complex(GO:0000974) |
0.1 | 0.6 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 2.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 1.0 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.5 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 0.5 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.0 | 0.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.5 | GO:0071437 | invadopodium(GO:0071437) |
0.0 | 0.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 1.0 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.0 | 1.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.6 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.0 | 0.3 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.0 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.0 | 0.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.3 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 2.6 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.4 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.4 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 2.7 | GO:0016234 | inclusion body(GO:0016234) |
0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
0.0 | 0.2 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 0.4 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 1.3 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 2.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.1 | GO:0032437 | cuticular plate(GO:0032437) |
0.0 | 0.2 | GO:0042825 | TAP complex(GO:0042825) |
0.0 | 1.0 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 1.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.1 | GO:0000125 | PCAF complex(GO:0000125) |
0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.1 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.1 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.5 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.0 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.2 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.2 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.1 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 1.0 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 1.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.6 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 1.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 1.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.0 | 0.3 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.1 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 2.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 0.4 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 3.6 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.2 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.6 | 3.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.4 | 2.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.3 | 1.0 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.3 | 1.6 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.3 | 1.2 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.3 | 4.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.3 | 1.4 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.2 | 0.2 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
0.2 | 1.2 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.2 | 1.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.2 | 0.6 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.2 | 0.6 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.2 | 1.2 | GO:0008494 | translation activator activity(GO:0008494) |
0.2 | 0.5 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
0.2 | 5.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.2 | 2.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.2 | 0.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 0.5 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 1.5 | GO:1903136 | cuprous ion binding(GO:1903136) |
0.1 | 0.4 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 1.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 0.4 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
0.1 | 0.7 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.5 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
0.1 | 0.9 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.1 | 0.6 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 0.4 | GO:1990254 | keratin filament binding(GO:1990254) |
0.1 | 0.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 0.4 | GO:0043546 | molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546) |
0.1 | 0.5 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 0.5 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.6 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.1 | 0.9 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.1 | 1.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 0.3 | GO:0003979 | UDP-glucose 6-dehydrogenase activity(GO:0003979) |
0.1 | 0.3 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.1 | 0.8 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.1 | 0.6 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.5 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.1 | 0.3 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
0.1 | 0.2 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.1 | 0.5 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 1.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.5 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 0.4 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
0.1 | 1.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.1 | 0.9 | GO:0031996 | thioesterase binding(GO:0031996) |
0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.8 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.1 | 1.6 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.1 | 2.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.1 | 0.2 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.1 | 0.8 | GO:0031386 | protein tag(GO:0031386) |
0.1 | 0.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.4 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
0.1 | 0.4 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 1.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.1 | 0.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 0.4 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.5 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.1 | 0.4 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
0.1 | 0.2 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.1 | 0.8 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.1 | 2.1 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.1 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.1 | 0.2 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
0.0 | 0.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.0 | 1.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 3.6 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.6 | GO:0048038 | quinone binding(GO:0048038) |
0.0 | 0.3 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.0 | 0.7 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.0 | 0.5 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.2 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980) |
0.0 | 0.2 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.0 | 0.2 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.0 | 1.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.3 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.0 | 0.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 2.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.2 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) siRNA binding(GO:0035197) |
0.0 | 0.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 1.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.2 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.0 | 0.2 | GO:0030275 | LRR domain binding(GO:0030275) |
0.0 | 0.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.0 | 0.6 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.0 | 1.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 1.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 2.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 1.1 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.2 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 0.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.1 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
0.0 | 0.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.1 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
0.0 | 1.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 3.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.1 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
0.0 | 0.0 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.0 | 0.4 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.1 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
0.0 | 0.2 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 0.1 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
0.0 | 0.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.0 | 0.4 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.2 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.0 | 0.5 | GO:0016417 | S-acyltransferase activity(GO:0016417) |
0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.5 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 0.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.3 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.1 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
0.0 | 0.1 | GO:0019825 | oxygen binding(GO:0019825) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.0 | 0.1 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.0 | 0.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 0.3 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.1 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.0 | 0.2 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.0 | 0.1 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.1 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.0 | 0.0 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.0 | 0.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.0 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.2 | 4.5 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.1 | 0.7 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 4.1 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.1 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.1 | 0.3 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.1 | 2.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.6 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
0.0 | 1.6 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 1.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 2.1 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.4 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.9 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.3 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.4 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 0.2 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 1.4 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 0.6 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 1.1 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.4 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
0.0 | 0.3 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 0.9 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 0.3 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.3 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 0.7 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.4 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.6 | REACTOME_KINESINS | Genes involved in Kinesins |
0.2 | 1.2 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.2 | 4.8 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 2.3 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.1 | 3.3 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 2.2 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
0.1 | 1.8 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.1 | 1.2 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 0.9 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.1 | 1.7 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 5.1 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.1 | 0.2 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 1.2 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.1 | 5.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 1.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.6 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.7 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.0 | 1.4 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.0 | 0.8 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 2.3 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 1.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 2.1 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
0.0 | 0.9 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.5 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.0 | 0.2 | REACTOME_REGULATION_OF_IFNA_SIGNALING | Genes involved in Regulation of IFNA signaling |
0.0 | 0.8 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.5 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 1.2 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 2.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.3 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 0.5 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.3 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.2 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK |
0.0 | 0.7 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.0 | 0.4 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.3 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 1.2 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 1.4 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.3 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.2 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 0.5 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.5 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.5 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.3 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 0.6 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 1.9 | REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
0.0 | 0.3 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.3 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.4 | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
0.0 | 0.6 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 1.7 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.0 | 0.8 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.0 | 2.8 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 1.6 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.0 | 0.1 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.2 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.3 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 0.1 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.0 | 0.3 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.1 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |