Motif ID: Myf6

Z-value: 2.540


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_36197343 22.070 ENSMUST00000115713.1
ENSMUST00000115712.1
Nrg2

neuregulin 2

chr9_-_112185939 21.242 ENSMUST00000070218.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr16_+_91269759 20.451 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr8_+_125995102 19.092 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr8_-_9771018 19.066 ENSMUST00000110969.3
Fam155a
family with sequence similarity 155, member A
chr3_+_118433797 18.158 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr15_-_66812593 15.057 ENSMUST00000100572.3
Sla
src-like adaptor
chr2_-_122611238 14.653 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_+_41532999 14.406 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chr9_+_27790947 14.029 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr11_+_50602072 13.446 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr5_+_30588078 11.730 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr18_+_65873478 10.239 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr16_-_67620880 9.765 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr2_-_71546745 9.672 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr6_-_126740151 9.458 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr13_-_76385028 9.355 ENSMUST00000099365.1
Gm10760
predicted gene 10760
chr16_+_41532851 9.242 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr12_+_108334341 8.915 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr1_-_3671498 8.787 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr11_+_104231573 8.703 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr2_-_104409992 8.650 ENSMUST00000149466.1
ENSMUST00000139015.1
D430041D05Rik

RIKEN cDNA D430041D05 gene

chr7_-_138397704 8.627 ENSMUST00000160436.1
Tcerg1l
transcription elongation regulator 1-like
chr9_-_98032983 8.473 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr11_-_6065538 8.440 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chrX_+_73503074 8.266 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr11_+_104231390 8.170 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr9_+_45370185 8.133 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr2_-_104410334 8.107 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr11_+_104231465 8.042 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr4_-_64046925 8.036 ENSMUST00000107377.3
Tnc
tenascin C
chr12_-_119238794 8.011 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr11_+_104231515 7.989 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr8_-_11312731 7.892 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr8_+_11312805 7.889 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr4_+_103619580 7.678 ENSMUST00000106827.1
Dab1
disabled 1
chr2_-_25319095 7.672 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr11_+_121702393 7.584 ENSMUST00000036742.7
Metrnl
meteorin, glial cell differentiation regulator-like
chr19_+_26605106 7.383 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr16_-_46496955 7.323 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3

poliovirus receptor-related 3

chr13_-_117025505 7.256 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr4_+_119814495 7.252 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr16_-_46496772 7.173 ENSMUST00000149901.1
ENSMUST00000096052.2
Pvrl3

poliovirus receptor-related 3

chr7_-_73740917 7.093 ENSMUST00000169090.1
A830073O21Rik
RIKEN cDNA A830073O21 gene
chr6_+_118066356 7.026 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr1_-_136260873 7.000 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr9_+_44043384 6.893 ENSMUST00000114840.1
Thy1
thymus cell antigen 1, theta
chr1_-_21961581 6.754 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr16_+_7069825 6.650 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_-_57197435 6.518 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197556 6.500 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr7_-_127021205 6.475 ENSMUST00000159916.1
Prrt2
proline-rich transmembrane protein 2
chr3_-_68870266 6.405 ENSMUST00000166328.1
Gm17641
predicted gene, 17641
chr7_+_3303643 6.391 ENSMUST00000172109.1
Prkcg
protein kinase C, gamma
chr19_-_57197377 6.386 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr3_+_68494208 6.384 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr14_+_33923582 6.363 ENSMUST00000168727.1
Gdf10
growth differentiation factor 10
chr5_-_137600650 6.301 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr7_+_122671378 6.196 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr6_-_121473630 6.186 ENSMUST00000046373.5
Iqsec3
IQ motif and Sec7 domain 3
chr2_-_25319187 6.156 ENSMUST00000114312.1
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr11_+_24076529 6.120 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr15_-_37459327 6.107 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr9_+_75625707 6.065 ENSMUST00000034702.4
Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_+_180598219 6.017 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr7_+_122289297 6.011 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr6_+_21215472 5.967 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr1_-_71653162 5.912 ENSMUST00000055226.6
Fn1
fibronectin 1
chr13_+_29014399 5.897 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr8_+_124793013 5.863 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr19_-_57197496 5.833 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr14_+_70555900 5.719 ENSMUST00000163060.1
Hr
hairless
chr8_-_84773381 5.697 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_+_68869563 5.692 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr7_+_73740277 5.654 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr11_-_108343917 5.622 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr13_-_51567084 5.585 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr14_-_102982630 5.563 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr8_+_124793061 5.521 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr2_-_131042682 5.513 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr4_-_15149051 5.389 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chr7_+_3303503 5.388 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr8_-_17535251 5.382 ENSMUST00000082104.6
Csmd1
CUB and Sushi multiple domains 1
chr17_+_35236556 5.327 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr10_+_24595623 5.279 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr17_-_46752170 5.266 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr3_+_65109343 5.231 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr2_-_131043088 5.179 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr18_+_60803838 5.094 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
Cd74


CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)


chr10_-_43174521 5.093 ENSMUST00000040275.7
Sobp
sine oculis-binding protein homolog (Drosophila)
chr3_-_141931523 5.090 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr14_+_65968483 5.085 ENSMUST00000022616.6
Clu
clusterin
chrX_+_99975570 5.056 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_+_16309577 5.013 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr10_-_75560330 4.930 ENSMUST00000051129.9
Fam211b
family with sequence similarity 211, member B
chr4_+_129984833 4.922 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr13_+_13437602 4.879 ENSMUST00000005532.7
Nid1
nidogen 1
chr16_-_67620805 4.785 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr11_+_101246960 4.767 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr14_+_19751257 4.761 ENSMUST00000022340.3
Nid2
nidogen 2
chr17_+_79051906 4.732 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr2_+_158666690 4.697 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr3_-_116253467 4.690 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr6_-_53068562 4.661 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr11_+_101246405 4.614 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr6_-_12749193 4.582 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr4_+_130913120 4.579 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr5_-_71095765 4.566 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr4_+_155694311 4.551 ENSMUST00000099265.2
B930041F14Rik
RIKEN cDNA B930041F14 gene
chr1_+_71652837 4.532 ENSMUST00000097699.2
Apol7d
apolipoprotein L 7d
chr10_+_116301374 4.496 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr12_+_51593315 4.449 ENSMUST00000164782.2
ENSMUST00000085412.5
Coch

coagulation factor C homolog (Limulus polyphemus)

chr1_-_22805994 4.442 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr4_+_102254993 4.420 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_102254739 4.411 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_+_7056731 4.313 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr8_-_73353477 4.264 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr17_-_83631892 4.257 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr10_-_116473418 4.249 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr10_+_90576708 4.232 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr6_+_125552948 4.220 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr8_+_27085520 4.201 ENSMUST00000178514.1
ENSMUST00000033876.7
Gpr124

G protein-coupled receptor 124

chr4_+_129985098 4.127 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr4_+_130913264 4.109 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr19_-_45816007 4.105 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2


Kv channel-interacting protein 2


chr12_+_69197200 4.086 ENSMUST00000181850.1
9330151L19Rik
RIKEN cDNA 9330151L19 gene
chr8_-_70487314 4.079 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr11_-_54028090 4.047 ENSMUST00000020586.6
Slc22a4
solute carrier family 22 (organic cation transporter), member 4
chr15_-_95528702 3.987 ENSMUST00000166170.1
Nell2
NEL-like 2
chr4_-_47057296 3.981 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr2_-_36104060 3.954 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr6_-_37299950 3.873 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr5_+_117413977 3.867 ENSMUST00000180430.1
Ksr2
kinase suppressor of ras 2
chr10_-_126901315 3.852 ENSMUST00000026504.5
ENSMUST00000168520.1
Xrcc6bp1

XRCC6 binding protein 1

chr16_-_74411292 3.837 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr13_+_93771656 3.823 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr2_+_158667119 3.807 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr7_+_88278085 3.787 ENSMUST00000032779.5
ENSMUST00000128791.1
Ctsc

cathepsin C

chr7_+_130936172 3.749 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chrX_+_114474312 3.710 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr1_+_42697146 3.703 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr15_-_78120011 3.683 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr4_-_106464167 3.669 ENSMUST00000049507.5
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr10_+_90576252 3.666 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chrX_+_73787062 3.657 ENSMUST00000002090.2
Ssr4
signal sequence receptor, delta
chr2_+_125136692 3.571 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr2_+_32095518 3.570 ENSMUST00000057423.5
Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr6_-_138422898 3.515 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr19_-_17837620 3.510 ENSMUST00000025618.8
ENSMUST00000050715.8
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr9_-_59036387 3.497 ENSMUST00000068664.5
Neo1
neogenin
chr10_+_90576777 3.486 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr2_-_151632471 3.464 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr2_-_148443543 3.433 ENSMUST00000099269.3
Cd93
CD93 antigen
chr10_+_90576570 3.413 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr11_+_78322965 3.412 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr6_+_107529717 3.366 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chr18_-_61536522 3.308 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chrX_+_152144240 3.295 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr9_-_89705017 3.275 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr18_-_35722330 3.270 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr13_-_23710714 3.249 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr2_+_107290590 3.247 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr16_-_52452654 3.232 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr8_-_85067982 3.231 ENSMUST00000177563.1
Gm5741
predicted gene 5741
chr7_+_107370728 3.211 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr9_-_22468294 3.203 ENSMUST00000034763.8
Rp9
retinitis pigmentosa 9 (human)
chr16_-_17576631 3.198 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr19_-_36919606 3.196 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr10_+_90576872 3.189 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr6_-_35308110 3.175 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr14_+_65971164 3.125 ENSMUST00000144619.1
Clu
clusterin
chr7_+_57591147 3.122 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_+_18672384 3.116 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3

COMM domain containing 3

chr3_-_8964037 3.105 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr9_-_40531362 3.102 ENSMUST00000119373.1
Gramd1b
GRAM domain containing 1B
chr9_+_66713686 3.101 ENSMUST00000071889.6
Car12
carbonic anyhydrase 12
chr9_+_66713719 3.066 ENSMUST00000085420.5
Car12
carbonic anyhydrase 12
chr6_+_6863769 3.062 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr16_-_4559720 3.030 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr15_+_78926720 3.027 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr16_+_17276337 3.017 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr8_-_84176552 3.016 ENSMUST00000070102.5
Nanos3
nanos homolog 3 (Drosophila)
chr9_+_30942541 3.014 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr5_+_71699918 3.003 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr3_-_89773221 2.984 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr4_-_124850473 2.983 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr9_+_40269273 2.968 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr3_+_138065052 2.952 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr3_+_123446913 2.948 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr1_-_134955908 2.945 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr9_+_40269430 2.919 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr10_+_11343387 2.918 ENSMUST00000069106.4
Epm2a
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr13_+_12702362 2.900 ENSMUST00000104944.2
Gm2399
predicted gene 2399
chr3_-_144202300 2.896 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr3_-_90389884 2.883 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr17_-_45595842 2.878 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr1_-_25228814 2.861 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr6_+_125145235 2.852 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr2_-_90580578 2.830 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr1_-_180195981 2.821 ENSMUST00000027766.6
ENSMUST00000161814.1
Adck3

aarF domain containing kinase 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.7 GO:0006601 creatine biosynthetic process(GO:0006601)
4.6 13.8 GO:1900673 olefin metabolic process(GO:1900673)
3.7 22.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
3.7 3.7 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
3.7 32.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
3.5 10.4 GO:1990034 calcium ion export from cell(GO:1990034)
3.4 10.2 GO:0061744 motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.2 9.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
2.9 20.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
2.8 8.4 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
2.4 11.8 GO:0032423 regulation of mismatch repair(GO:0032423)
2.3 11.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
2.0 6.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.9 7.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477)
1.9 7.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.8 14.2 GO:0030322 stabilization of membrane potential(GO:0030322)
1.7 20.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.7 8.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.7 5.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.6 4.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.6 9.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.5 4.5 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.5 4.4 GO:0072720 response to dithiothreitol(GO:0072720)
1.4 6.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.4 8.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 8.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.3 5.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.3 10.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.3 5.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.3 5.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.2 4.7 GO:0061743 motor learning(GO:0061743)
1.1 30.5 GO:0035641 locomotory exploration behavior(GO:0035641)
1.1 4.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
1.1 11.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.1 3.2 GO:0002725 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of T cell cytokine production(GO:0002725)
1.1 4.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.1 8.6 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.9 6.5 GO:0015879 carnitine transport(GO:0015879)
0.9 3.7 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.9 1.8 GO:0072284 metanephric S-shaped body morphogenesis(GO:0072284)
0.9 2.7 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.9 2.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.9 6.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.8 0.8 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.8 13.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.8 7.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.8 5.6 GO:0003096 renal sodium ion transport(GO:0003096)
0.8 2.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.8 2.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.8 5.5 GO:0015862 uridine transport(GO:0015862)
0.8 2.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.8 3.1 GO:0015871 choline transport(GO:0015871)
0.8 2.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.7 11.9 GO:0030574 collagen catabolic process(GO:0030574)
0.7 3.7 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.7 2.9 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.7 2.9 GO:1905167 astrocyte activation involved in immune response(GO:0002265) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.7 2.8 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.7 2.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.7 7.0 GO:0046959 habituation(GO:0046959)
0.7 5.5 GO:0005513 detection of calcium ion(GO:0005513)
0.7 6.1 GO:0071420 cellular response to histamine(GO:0071420)
0.7 8.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.7 2.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.7 0.7 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.7 4.0 GO:0032796 uropod organization(GO:0032796)
0.7 4.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.7 1.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.7 2.0 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.6 4.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.6 2.6 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.6 1.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 3.7 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.6 3.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.6 2.5 GO:0072014 proximal tubule development(GO:0072014)
0.6 2.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.6 1.2 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.6 1.7 GO:1990523 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) bone regeneration(GO:1990523)
0.6 11.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.6 1.7 GO:0016095 polyprenol catabolic process(GO:0016095)
0.6 1.7 GO:0015886 heme transport(GO:0015886)
0.5 4.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.5 0.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.5 2.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.5 3.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5 1.1 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.5 1.6 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.5 5.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 1.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 21.1 GO:0034605 cellular response to heat(GO:0034605)
0.5 3.5 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.5 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 26.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.5 1.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.5 1.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.5 8.5 GO:0001553 luteinization(GO:0001553)
0.5 1.4 GO:1900365 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.5 8.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 12.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.5 2.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.5 4.1 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.4 8.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 9.0 GO:0045475 locomotor rhythm(GO:0045475)
0.4 1.2 GO:0060066 oviduct development(GO:0060066)
0.4 1.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 0.8 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.4 1.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.4 2.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 2.7 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 1.5 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.4 5.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.4 1.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.4 6.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 2.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.3 3.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.3 1.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.3 0.9 GO:0006667 sphinganine metabolic process(GO:0006667)
0.3 1.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 3.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.3 1.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 2.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.3 25.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 4.4 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.3 0.3 GO:1901678 iron coordination entity transport(GO:1901678)
0.3 3.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 1.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 9.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.3 4.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 2.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 2.8 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 5.4 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.3 1.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 33.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.3 1.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.3 2.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 1.0 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.3 1.0 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.2 2.7 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.2 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.9 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 2.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 0.7 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.2 3.2 GO:0008272 sulfate transport(GO:0008272)
0.2 1.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.9 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 4.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.4 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 3.6 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 2.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2 0.6 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.2 2.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 1.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.8 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.2 18.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.2 2.0 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 2.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 3.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.2 0.5 GO:1902745 positive regulation of lamellipodium organization(GO:1902745)
0.2 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 3.2 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 0.3 GO:0030578 PML body organization(GO:0030578)
0.2 2.8 GO:0000338 protein deneddylation(GO:0000338)
0.2 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.6 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.5 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 7.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.2 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 1.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.6 GO:0032060 bleb assembly(GO:0032060)
0.1 1.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 1.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.8 GO:0033572 transferrin transport(GO:0033572)
0.1 3.8 GO:0009268 response to pH(GO:0009268)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.4 GO:0097104 postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.8 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 2.2 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 4.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 9.0 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 12.5 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 3.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.5 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.5 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.6 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.1 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.6 GO:0051453 regulation of intracellular pH(GO:0051453)
0.1 2.1 GO:0060074 synapse maturation(GO:0060074)
0.1 0.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 8.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 7.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 1.3 GO:0042182 ketone catabolic process(GO:0042182)
0.1 1.5 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 2.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0051604 protein maturation(GO:0051604)
0.1 0.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 2.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.5 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 2.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.5 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 1.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.7 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 4.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 2.2 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.2 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.9 GO:0044803 multi-organism membrane organization(GO:0044803)
0.1 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.1 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 6.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 2.4 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.1 GO:0050818 regulation of coagulation(GO:0050818)
0.0 1.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 2.6 GO:0015992 proton transport(GO:0015992)
0.0 0.4 GO:0071578 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0043144 snoRNA processing(GO:0043144)
0.0 3.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 2.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.5 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 2.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.3 GO:0030168 platelet activation(GO:0030168)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.8 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 1.2 GO:0031638 zymogen activation(GO:0031638)
0.0 1.0 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.2 GO:0032612 interleukin-1 beta production(GO:0032611) interleukin-1 production(GO:0032612)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.6 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0010038 response to metal ion(GO:0010038)
0.0 0.2 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 19.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
3.5 13.8 GO:0044307 dendritic branch(GO:0044307)
3.4 40.7 GO:0097418 neurofibrillary tangle(GO:0097418)
3.2 15.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
2.0 6.1 GO:0005577 fibrinogen complex(GO:0005577)
1.9 9.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.2 5.0 GO:0005594 collagen type IX trimer(GO:0005594)
1.2 3.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.0 2.9 GO:0043083 synaptic cleft(GO:0043083)
1.0 3.8 GO:0032280 symmetric synapse(GO:0032280)
0.9 3.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.9 0.9 GO:0019034 viral replication complex(GO:0019034)
0.9 13.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.9 4.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.8 4.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.7 3.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7 5.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 28.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.6 3.2 GO:1990357 terminal web(GO:1990357)
0.6 3.8 GO:0016011 dystroglycan complex(GO:0016011)
0.6 1.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.6 8.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 9.0 GO:1990635 proximal dendrite(GO:1990635)
0.6 6.1 GO:0032426 stereocilium tip(GO:0032426)
0.5 3.1 GO:0005859 muscle myosin complex(GO:0005859)
0.5 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.5 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 8.0 GO:0005614 interstitial matrix(GO:0005614)
0.5 2.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.5 1.4 GO:0044194 cytolytic granule(GO:0044194)
0.4 35.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 3.7 GO:0005883 neurofilament(GO:0005883)
0.4 2.4 GO:0005955 calcineurin complex(GO:0005955)
0.4 1.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.4 1.9 GO:0005827 polar microtubule(GO:0005827)
0.4 1.5 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.4 12.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 5.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.4 9.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 1.3 GO:0070820 tertiary granule(GO:0070820)
0.3 1.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 9.6 GO:0051233 spindle midzone(GO:0051233)
0.3 1.4 GO:0032437 cuticular plate(GO:0032437)
0.3 3.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 3.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 4.2 GO:0042101 T cell receptor complex(GO:0042101)
0.3 3.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 5.1 GO:0005581 collagen trimer(GO:0005581)
0.2 4.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.2 3.2 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 29.3 GO:0031225 anchored component of membrane(GO:0031225)
0.2 3.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 6.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 24.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 4.1 GO:0071564 npBAF complex(GO:0071564)
0.2 4.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 14.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.8 GO:0070852 cell body fiber(GO:0070852)
0.2 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.7 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.2 GO:0043219 lateral loop(GO:0043219)
0.2 1.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 0.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 8.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 5.2 GO:0031672 A band(GO:0031672)
0.1 2.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 6.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 15.1 GO:0005903 brush border(GO:0005903)
0.1 6.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 33.9 GO:0097060 synaptic membrane(GO:0097060)
0.1 1.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 7.0 GO:0043204 perikaryon(GO:0043204)
0.1 3.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 4.3 GO:0043235 receptor complex(GO:0043235)
0.1 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.5 GO:0014704 intercalated disc(GO:0014704)
0.1 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 4.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.7 GO:0016235 aggresome(GO:0016235)
0.1 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.1 13.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0045178 basal part of cell(GO:0045178)
0.0 1.9 GO:0009986 cell surface(GO:0009986)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 2.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 3.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.1 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
6.7 20.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
5.8 17.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
4.7 32.9 GO:0099609 microtubule lateral binding(GO:0099609)
3.6 10.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
3.1 33.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.7 10.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
2.3 11.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
2.3 13.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.9 9.4 GO:0097643 amylin receptor activity(GO:0097643)
1.6 6.5 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.4 6.9 GO:0034235 GPI anchor binding(GO:0034235)
1.3 8.0 GO:0045545 syndecan binding(GO:0045545)
1.2 8.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.2 3.7 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
1.1 7.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.0 5.1 GO:0042289 MHC class II protein binding(GO:0042289)
1.0 5.9 GO:0045340 mercury ion binding(GO:0045340)
1.0 2.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.0 8.6 GO:0039706 co-receptor binding(GO:0039706)
0.9 2.8 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.9 2.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 7.8 GO:0043237 laminin-1 binding(GO:0043237)
0.8 14.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.8 2.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.8 3.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.8 2.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.8 4.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.8 12.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.7 5.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.7 2.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.7 2.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.7 2.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.7 13.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 3.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 5.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.6 3.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 14.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.6 2.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.6 3.0 GO:0005534 galactose binding(GO:0005534)
0.6 2.9 GO:2001070 starch binding(GO:2001070)
0.6 4.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.6 2.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.6 3.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 5.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 1.7 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.6 1.7 GO:0015232 heme transporter activity(GO:0015232)
0.6 3.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 6.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 8.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.5 6.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.5 1.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5 1.4 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.4 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 2.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 4.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 22.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 8.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.4 1.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.4 12.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 4.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 2.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 3.8 GO:0031404 chloride ion binding(GO:0031404)
0.4 4.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 4.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.4 2.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 4.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 4.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 8.4 GO:0043274 phospholipase binding(GO:0043274)
0.3 11.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 7.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 2.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 14.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.3 9.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 6.0 GO:0004697 protein kinase C activity(GO:0004697)
0.3 0.9 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.3 1.2 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.3 6.7 GO:0001968 fibronectin binding(GO:0001968)
0.3 3.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 3.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 2.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 2.9 GO:0070097 delta-catenin binding(GO:0070097)
0.3 10.3 GO:0030552 cAMP binding(GO:0030552)
0.3 8.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 2.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 1.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 2.5 GO:0015250 water channel activity(GO:0015250)
0.2 3.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 2.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 3.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.9 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 0.7 GO:2001069 glycogen binding(GO:2001069)
0.2 1.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.2 4.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 2.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 1.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 6.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 3.6 GO:0030506 ankyrin binding(GO:0030506)
0.2 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 5.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 14.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 4.1 GO:0030507 spectrin binding(GO:0030507)
0.2 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 4.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 17.3 GO:0016247 channel regulator activity(GO:0016247)
0.2 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) neuroligin family protein binding(GO:0097109)
0.2 13.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.5 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 2.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 5.1 GO:0071837 HMG box domain binding(GO:0071837)
0.2 4.7 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.6 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 2.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 4.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 5.0 GO:0005179 hormone activity(GO:0005179)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 2.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.3 GO:0071074 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.4 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 2.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.9 GO:0070628 proteasome binding(GO:0070628)
0.1 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 6.0 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.1 2.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 2.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 5.2 GO:0051117 ATPase binding(GO:0051117)
0.1 9.3 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 1.8 GO:0017022 myosin binding(GO:0017022)
0.0 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 6.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 15.1 GO:0003779 actin binding(GO:0003779)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 5.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 1.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.9 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 2.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.1 GO:0008083 growth factor activity(GO:0008083)
0.0 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 3.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.0 GO:0017171 serine hydrolase activity(GO:0017171)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 29.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
1.2 17.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
1.1 7.8 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.8 28.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.7 24.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.7 12.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 11.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.5 15.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.3 8.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.3 5.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 1.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.3 2.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.3 3.8 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 34.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 2.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 1.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 2.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 6.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.2 1.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 1.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 4.3 PID_EPO_PATHWAY EPO signaling pathway
0.2 1.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 5.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.7 PID_BMP_PATHWAY BMP receptor signaling
0.1 3.4 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.0 ST_ADRENERGIC Adrenergic Pathway
0.1 1.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 0.7 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 2.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 6.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 6.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 0.7 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 2.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 9.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 6.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 1.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 1.7 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.0 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 2.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 2.0 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 2.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 3.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 33.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
2.8 5.6 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
1.3 8.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.1 22.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.1 6.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.0 41.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
1.0 23.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 22.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.9 13.9 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.9 31.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.8 13.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.8 17.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.8 17.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 31.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.6 8.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.6 10.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.6 7.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.6 5.3 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 7.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 4.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 1.7 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 17.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 10.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.3 11.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.3 2.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 2.0 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 6.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 2.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 4.5 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 7.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.2 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 5.0 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 4.2 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.2 3.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 8.5 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.2 1.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 3.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 1.5 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 11.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 4.0 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 4.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.0 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 4.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.1 3.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 15.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 6.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.9 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 0.6 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 5.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.6 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.5 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism