Motif ID: Myf6

Z-value: 2.540


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_36197343 22.070 ENSMUST00000115713.1
ENSMUST00000115712.1
 Nrg2

neuregulin 2

chr9_-_112185939 21.242 ENSMUST00000070218.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr16_+_91269759 20.451 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr8_+_125995102 19.092 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr8_-_9771018 19.066 ENSMUST00000110969.3
 Fam155a
family with sequence similarity 155, member A
chr3_+_118433797 18.158 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr15_-_66812593 15.057 ENSMUST00000100572.3
 Sla
src-like adaptor
chr2_-_122611238 14.653 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_+_41532999 14.406 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr9_+_27790947 14.029 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr11_+_50602072 13.446 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr5_+_30588078 11.730 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr18_+_65873478 10.239 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr16_-_67620880 9.765 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr2_-_71546745 9.672 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr6_-_126740151 9.458 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr13_-_76385028 9.355 ENSMUST00000099365.1
 Gm10760
predicted gene 10760
chr16_+_41532851 9.242 ENSMUST00000078873.4
 Lsamp
limbic system-associated membrane protein
chr12_+_108334341 8.915 ENSMUST00000021684.4
 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr1_-_3671498 8.787 ENSMUST00000070533.4
 Xkr4
X Kell blood group precursor related family member 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 286 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 33.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
3.7 32.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.1 30.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.5 26.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3 25.8 GO:0030032 lamellipodium assembly(GO:0030032)
3.7 22.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.5 21.1 GO:0034605 cellular response to heat(GO:0034605)
1.7 20.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
2.9 20.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 18.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
4.9 14.7 GO:0006601 creatine biosynthetic process(GO:0006601)
1.8 14.2 GO:0030322 stabilization of membrane potential(GO:0030322)
4.6 13.8 GO:1900673 olefin metabolic process(GO:1900673)
0.8 13.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 12.5 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.5 12.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.7 11.9 GO:0030574 collagen catabolic process(GO:0030574)
2.4 11.8 GO:0032423 regulation of mismatch repair(GO:0032423)
2.3 11.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.6 11.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 40.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 35.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 33.9 GO:0097060 synaptic membrane(GO:0097060)
0.2 29.3 GO:0031225 anchored component of membrane(GO:0031225)
0.7 28.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 24.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
4.8 19.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
3.2 15.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 15.1 GO:0005903 brush border(GO:0005903)
0.2 14.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
3.5 13.8 GO:0044307 dendritic branch(GO:0044307)
0.9 13.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 13.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 12.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 9.6 GO:0051233 spindle midzone(GO:0051233)
0.4 9.5 GO:0000930 gamma-tubulin complex(GO:0000930)
1.9 9.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.6 9.0 GO:1990635 proximal dendrite(GO:1990635)
0.2 8.8 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 209 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 33.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
4.7 32.9 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 22.4 GO:0046875 ephrin receptor binding(GO:0046875)
7.4 22.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
6.7 20.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
5.8 17.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 17.3 GO:0016247 channel regulator activity(GO:0016247)
0.0 15.1 GO:0003779 actin binding(GO:0003779)
0.8 14.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.6 14.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.3 14.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 14.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
2.3 13.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 13.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 13.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 12.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 12.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.3 11.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 11.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
3.6 10.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 34.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.5 29.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.8 28.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.7 24.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
1.2 17.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.5 15.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.7 12.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 11.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 9.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.3 8.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
1.1 7.8 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.2 6.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 6.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 6.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 6.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.2 5.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.3 5.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.7 PID_BMP_PATHWAY BMP receptor signaling
0.2 4.3 PID_EPO_PATHWAY EPO signaling pathway
0.3 3.8 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 41.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
4.8 33.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.9 31.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.7 31.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
1.0 23.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.9 22.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
1.1 22.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 17.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.8 17.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8 17.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 15.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.9 13.9 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.8 13.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.3 11.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 11.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 10.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 10.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.3 8.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.2 8.5 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.6 8.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis