Motif ID: Myod1

Z-value: 0.541


Transcription factors associated with Myod1:

Gene SymbolEntrez IDGene Name
Myod1 ENSMUSG00000009471.3 Myod1



Activity profile for motif Myod1.

activity profile for motif Myod1


Sorted Z-values histogram for motif Myod1

Sorted Z-values for motif Myod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Myod1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_78773452 3.462 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_34528844 3.422 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr10_-_8518801 2.421 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr11_-_114795888 2.288 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr13_-_97747373 2.068 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr5_+_64812336 1.873 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr1_-_97977233 1.837 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr7_+_96210107 1.818 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr3_+_90537242 1.810 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 1.750 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr17_-_35703971 1.712 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr13_-_97747399 1.708 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_-_107915041 1.689 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr1_-_119053339 1.561 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr17_-_35700520 1.547 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr2_-_84775420 1.538 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr17_-_35704000 1.527 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr15_+_25622525 1.515 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr2_-_84775388 1.513 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr18_-_82406777 1.387 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr4_-_82705735 1.334 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr16_-_46010212 1.314 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_+_45639964 1.301 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr5_-_99252839 1.296 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr16_+_43510267 1.246 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr3_-_84305385 1.187 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr8_+_94977101 1.186 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chrX_-_142306170 1.147 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr17_-_35702297 1.137 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr15_-_99875382 1.124 ENSMUST00000073691.3
Lima1
LIM domain and actin binding 1
chr5_-_28210022 1.106 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr19_-_45560508 1.098 ENSMUST00000026239.6
Poll
polymerase (DNA directed), lambda
chr2_-_118762607 1.074 ENSMUST00000059997.8
A430105I19Rik
RIKEN cDNA A430105I19 gene
chr5_+_105415738 1.068 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr6_+_112273758 1.059 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr7_+_122289297 1.031 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr17_-_72603709 1.029 ENSMUST00000086639.4
Alk
anaplastic lymphoma kinase
chr9_-_42124276 1.022 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr5_+_134986191 1.020 ENSMUST00000094245.2
Cldn3
claudin 3
chr11_-_48826655 1.017 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr17_+_80944611 1.012 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr1_-_118982551 1.000 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr7_+_45216671 0.997 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr2_-_62483637 0.971 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr4_+_46039202 0.962 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chr12_+_81026800 0.958 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr7_+_27607997 0.946 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr4_-_133967235 0.929 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_99864476 0.927 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr5_+_123015010 0.911 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr4_+_11156411 0.889 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr3_-_116807733 0.885 ENSMUST00000159670.1
Agl
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr2_-_127521358 0.868 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chr7_+_27607748 0.842 ENSMUST00000136962.1
Akt2
thymoma viral proto-oncogene 2
chr2_+_156840966 0.829 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr11_-_48826500 0.779 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr8_+_95352258 0.760 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr14_-_70207637 0.757 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr6_-_125494754 0.743 ENSMUST00000032492.8
Cd9
CD9 antigen
chr4_-_133967296 0.743 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_115163333 0.740 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr4_-_108031938 0.732 ENSMUST00000106708.1
Podn
podocan
chr7_+_121707189 0.728 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr10_+_128909866 0.724 ENSMUST00000026407.7
Cd63
CD63 antigen
chr6_-_54566484 0.723 ENSMUST00000019268.4
Scrn1
secernin 1
chr15_+_99717515 0.722 ENSMUST00000023760.6
ENSMUST00000162194.1
Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr7_+_130936172 0.716 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr17_+_88440711 0.709 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr15_+_99601372 0.681 ENSMUST00000023754.5
Aqp6
aquaporin 6
chr5_-_28210168 0.673 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr3_+_95588990 0.665 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chrX_-_23266751 0.658 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr4_+_133176336 0.657 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr8_-_69184177 0.657 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr6_-_93913678 0.655 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_4510472 0.653 ENSMUST00000068004.6
Pcx
pyruvate carboxylase
chr5_+_91517615 0.644 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr11_-_69605829 0.640 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_53511695 0.638 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr3_-_108210438 0.638 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr2_-_116065047 0.628 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chr13_+_51846673 0.628 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr6_+_56017489 0.614 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr4_-_135494499 0.602 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr14_+_62292475 0.600 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr7_+_127211608 0.596 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_42168603 0.595 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr7_-_131410325 0.590 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr5_-_73191848 0.588 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr8_-_4217133 0.581 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr18_-_23041641 0.566 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr6_-_134632388 0.564 ENSMUST00000047443.3
Mansc1
MANSC domain containing 1
chr11_+_43528759 0.563 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr7_-_123369870 0.561 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17


Rho GTPase activating protein 17


chr4_-_135494615 0.544 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr12_-_98737405 0.537 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr9_+_120929216 0.537 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr3_+_95588960 0.530 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr2_+_156840077 0.530 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr9_+_57072024 0.518 ENSMUST00000169879.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chr18_+_57142782 0.508 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr11_-_118909487 0.505 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr6_-_37299950 0.497 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chrX_-_12128350 0.491 ENSMUST00000123004.1
Bcor
BCL6 interacting corepressor
chr1_+_171250416 0.491 ENSMUST00000111315.1
ENSMUST00000006570.5
Adamts4

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4

chr7_+_27591705 0.491 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr15_+_78926720 0.485 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr8_-_61902669 0.484 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr9_+_46998931 0.484 ENSMUST00000178065.1
Gm4791
predicted gene 4791
chr6_+_125494419 0.480 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr3_+_95588928 0.477 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chrX_+_140956892 0.476 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr8_+_127064107 0.468 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr11_+_98358368 0.465 ENSMUST00000018311.4
Stard3
START domain containing 3
chr3_+_89436699 0.464 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr2_+_31759993 0.459 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chrX_-_16911774 0.458 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr5_-_21701332 0.456 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr9_+_57560934 0.454 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr7_+_67952817 0.451 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr2_-_114052804 0.439 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr3_+_146404844 0.431 ENSMUST00000106149.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr5_+_34989473 0.431 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr6_-_34910563 0.431 ENSMUST00000152488.1
ENSMUST00000149448.1
ENSMUST00000133336.1
Wdr91


WD repeat domain 91


chr7_+_142472080 0.428 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr11_-_90687572 0.424 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
Tom1l1



target of myb1-like 1 (chicken)



chr14_+_31019183 0.418 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr9_-_52679429 0.417 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr3_+_86224665 0.417 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr9_-_54501496 0.413 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr8_+_45885479 0.412 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr1_-_120121030 0.412 ENSMUST00000027634.6
Dbi
diazepam binding inhibitor
chr1_-_120120937 0.411 ENSMUST00000151708.1
Dbi
diazepam binding inhibitor
chr2_+_20519776 0.408 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr1_+_156558759 0.406 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr14_+_30879257 0.406 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr13_-_98890974 0.405 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr11_+_71749914 0.403 ENSMUST00000150531.1
Wscd1
WSC domain containing 1
chr2_-_120539852 0.402 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr6_-_99666762 0.401 ENSMUST00000032151.2
Eif4e3
eukaryotic translation initiation factor 4E member 3
chr3_-_19264959 0.398 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr7_-_25390098 0.397 ENSMUST00000054301.7
Lipe
lipase, hormone sensitive
chr14_+_31019159 0.392 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chrX_+_36328353 0.392 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr4_+_122995944 0.380 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr3_-_32365608 0.380 ENSMUST00000168566.1
Zmat3
zinc finger matrin type 3
chr7_-_97332017 0.379 ENSMUST00000139582.2
Usp35
ubiquitin specific peptidase 35
chr10_+_127063599 0.379 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr2_-_30415509 0.378 ENSMUST00000134120.1
ENSMUST00000102854.3
Crat

carnitine acetyltransferase

chr4_-_43523388 0.373 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chr11_-_95076797 0.373 ENSMUST00000145671.1
ENSMUST00000120375.1
Itga3

integrin alpha 3

chr3_-_32365643 0.369 ENSMUST00000029199.5
Zmat3
zinc finger matrin type 3
chr9_+_35421541 0.369 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr2_-_30415389 0.368 ENSMUST00000142096.1
Crat
carnitine acetyltransferase
chr10_+_127420334 0.367 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr7_-_80403315 0.366 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr1_+_63273261 0.365 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr2_-_52335134 0.364 ENSMUST00000075301.3
Neb
nebulin
chr3_+_146404631 0.361 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
Ssx2ip



synovial sarcoma, X breakpoint 2 interacting protein



chr1_+_55406163 0.358 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr7_+_142471838 0.354 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr4_+_98923908 0.350 ENSMUST00000169053.1
Usp1
ubiquitin specific peptidase 1
chr9_+_109095427 0.350 ENSMUST00000072093.6
Plxnb1
plexin B1
chr7_-_98145472 0.350 ENSMUST00000098281.2
Omp
olfactory marker protein
chr18_+_36559972 0.348 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr8_-_122699066 0.347 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr14_+_64652524 0.345 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr3_+_146404978 0.345 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr11_-_100770926 0.343 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr4_-_43523746 0.340 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chr9_-_67760208 0.339 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr1_-_133424377 0.336 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr11_+_68692070 0.332 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr9_-_24503127 0.331 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr11_+_83964419 0.331 ENSMUST00000049714.8
ENSMUST00000092834.5
ENSMUST00000183714.1
ENSMUST00000183456.1
Synrg



synergin, gamma



chr3_+_88616133 0.329 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr6_+_54681687 0.328 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr11_+_32205483 0.327 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr5_+_115011111 0.326 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr4_+_147940859 0.326 ENSMUST00000103232.1
2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr9_-_50693799 0.322 ENSMUST00000120622.1
Dixdc1
DIX domain containing 1
chr11_-_54962903 0.318 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr2_-_10048580 0.318 ENSMUST00000026888.4
Taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_47289394 0.317 ENSMUST00000079195.5
Stox2
storkhead box 2
chrX_-_74023745 0.317 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1

interleukin-1 receptor-associated kinase 1

chr3_+_89436736 0.314 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr4_+_43669610 0.313 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr9_+_44981779 0.313 ENSMUST00000034602.7
Cd3d
CD3 antigen, delta polypeptide
chr12_+_4917376 0.312 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr1_+_87327044 0.310 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr6_-_134566913 0.301 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr1_-_156036473 0.298 ENSMUST00000097527.3
ENSMUST00000027738.7
Tor1aip1

torsin A interacting protein 1

chr14_+_31019125 0.294 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr3_+_95434386 0.293 ENSMUST00000102749.4
ENSMUST00000090804.5
ENSMUST00000107161.1
ENSMUST00000107160.1
ENSMUST00000015666.10
Arnt




aryl hydrocarbon receptor nuclear translocator




chr17_+_47737030 0.293 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr7_+_101394361 0.293 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chrX_-_12128386 0.289 ENSMUST00000145872.1
Bcor
BCL6 interacting corepressor
chrX_+_161717055 0.288 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr5_-_135251209 0.287 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr6_-_148831395 0.287 ENSMUST00000145960.1
Ipo8
importin 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.6 2.6 GO:0060032 notochord regression(GO:0060032)
0.5 5.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 1.4 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.5 1.8 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 2.3 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 1.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 3.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.3 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 3.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 0.9 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.3 0.8 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324)
0.3 1.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 0.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 1.0 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.2 0.7 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.2 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.2 0.5 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.2 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 0.6 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 1.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.2 1.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 1.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.6 GO:0010288 response to lead ion(GO:0010288)
0.2 1.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 0.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.2 0.5 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.7 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 1.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.1 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.3 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.3 GO:1990523 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) bone regeneration(GO:1990523)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.4 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.1 0.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.4 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 1.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.6 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 1.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 1.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 1.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.5 GO:0046959 habituation(GO:0046959)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.1 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.6 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.4 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.3 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:1902065 response to L-glutamate(GO:1902065)
0.0 0.2 GO:0061009 common bile duct development(GO:0061009)
0.0 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.0 0.1 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.6 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0042534 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0 1.4 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 2.6 GO:0097542 ciliary tip(GO:0097542)
0.2 0.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:0097513 myosin II filament(GO:0097513)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 3.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0043219 lateral loop(GO:0043219)
0.1 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 2.3 GO:0016459 myosin complex(GO:0016459)
0.0 4.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 5.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 5.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 1.4 GO:0004966 galanin receptor activity(GO:0004966)
0.3 0.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 1.0 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.2 0.7 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 1.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 3.6 GO:0001848 complement binding(GO:0001848)
0.2 1.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 3.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0009374 biotin binding(GO:0009374)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 1.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.2 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 1.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 3.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248) cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 2.8 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.1 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 4.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.1 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 3.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 0.9 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 0.5 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 3.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.7 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.4 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.9 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors