Motif ID: Neurod1

Z-value: 0.873


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.758.2e-08Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_78773452 5.395 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_28210022 5.194 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr1_+_6730051 5.051 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr2_-_84775388 4.652 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775420 4.596 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_+_56017489 4.410 ENSMUST00000052827.4
 Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr16_+_42907563 4.179 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr12_-_34528844 3.865 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr6_-_127151044 3.783 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr7_-_28302238 3.690 ENSMUST00000108315.3
 Dll3
delta-like 3 (Drosophila)
chr1_-_155232710 3.666 ENSMUST00000035914.3
 BC034090
cDNA sequence BC034090
chr5_+_3343893 3.632 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr1_+_6730135 3.413 ENSMUST00000155921.1
 St18
suppression of tumorigenicity 18
chr13_+_51846673 3.405 ENSMUST00000021903.2
 Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr15_+_25622525 3.310 ENSMUST00000110457.1
ENSMUST00000137601.1
 Myo10

myosin X

chr7_+_127211608 3.280 ENSMUST00000032910.6
 Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr13_-_97747373 3.099 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_-_37770757 3.044 ENSMUST00000176680.1
 Zfp536
zinc finger protein 536
chr10_-_92164666 3.017 ENSMUST00000183123.1
ENSMUST00000182033.1
 Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr13_-_97747399 2.971 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 9.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.6 7.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.6 5.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.6 4.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 4.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.4 4.5 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 4.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 4.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.4 4.0 GO:0030035 microspike assembly(GO:0030035)
0.3 3.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.7 3.7 GO:0007386 compartment pattern specification(GO:0007386)
0.6 3.6 GO:0003383 apical constriction(GO:0003383)
0.2 3.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 3.4 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.2 3.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 3.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 2.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.0 2.6 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.3 2.5 GO:0001842 neural fold formation(GO:0001842)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.0 GO:0032993 protein-DNA complex(GO:0032993)
0.1 8.6 GO:0072562 blood microparticle(GO:0072562)
0.1 6.5 GO:0016459 myosin complex(GO:0016459)
0.4 6.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 5.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.2 4.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 4.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 4.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 4.0 GO:0030175 filopodium(GO:0030175)
0.1 3.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 3.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 2.8 GO:0033269 internode region of axon(GO:0033269)
0.6 2.5 GO:0090537 CERF complex(GO:0090537)
0.2 2.2 GO:0097542 ciliary tip(GO:0097542)
0.1 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.8 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.2 GO:0001848 complement binding(GO:0001848)
0.0 7.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.8 5.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 5.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 5.3 GO:0001047 core promoter binding(GO:0001047)
0.1 5.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 4.5 GO:0051015 actin filament binding(GO:0051015)
0.6 4.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 3.7 GO:0005112 Notch binding(GO:0005112)
1.2 3.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 3.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 3.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 3.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 3.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.7 2.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 4.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 4.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 3.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 3.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 3.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 3.1 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 3.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.8 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 2.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 2.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.5 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 9.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 8.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.3 5.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 4.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 3.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 3.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.0 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.0 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.9 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides