Motif ID: Neurog2

Z-value: 0.292


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_127633140-0.086.5e-01Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_54156039 0.573 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr1_-_111864869 0.495 ENSMUST00000035462.5
 Dsel
dermatan sulfate epimerase-like
chr16_+_43235856 0.431 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_-_25200110 0.400 ENSMUST00000100012.2
 Akap7
A kinase (PRKA) anchor protein 7
chr19_+_20601958 0.373 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr8_+_33428709 0.373 ENSMUST00000059351.7
 5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr1_+_42697146 0.371 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr3_+_118430299 0.341 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr5_+_129096740 0.330 ENSMUST00000056617.7
ENSMUST00000156437.1
 Gpr133

G protein-coupled receptor 133

chr13_-_97747399 0.292 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_-_84259812 0.287 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr3_+_138065052 0.251 ENSMUST00000163080.2
 1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr11_+_53433299 0.250 ENSMUST00000018382.6
 Gdf9
growth differentiation factor 9
chr3_-_107333289 0.249 ENSMUST00000061772.9
 Rbm15
RNA binding motif protein 15
chr17_-_25792284 0.241 ENSMUST00000072735.7
 Fam173a
family with sequence similarity 173, member A
chr2_-_79456750 0.238 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr11_-_69602741 0.230 ENSMUST00000138694.1
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr13_+_37345338 0.225 ENSMUST00000021860.5
 Ly86
lymphocyte antigen 86
chrX_+_141475385 0.202 ENSMUST00000112931.1
ENSMUST00000112930.1
 Col4a5

collagen, type IV, alpha 5

chr10_-_70655934 0.201 ENSMUST00000162144.1
ENSMUST00000162793.1
 Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.0 0.2 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:2000483 detection of bacterium(GO:0016045) response to bacterial lipoprotein(GO:0032493) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation