Motif ID: Nfatc2

Z-value: 1.503


Transcription factors associated with Nfatc2:

Gene SymbolEntrez IDGene Name
Nfatc2 ENSMUSG00000027544.10 Nfatc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc2mm10_v2_chr2_-_168601620_1686016570.173.3e-01Click!


Activity profile for motif Nfatc2.

activity profile for motif Nfatc2


Sorted Z-values histogram for motif Nfatc2

Sorted Z-values for motif Nfatc2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3000922 14.157 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3027439 12.543 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3004457 12.201 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3023547 11.959 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3013140 11.588 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr9_+_3017408 11.505 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3037111 10.704 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr9_+_3005125 10.378 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3034599 10.288 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3036877 10.062 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chrX_-_61185558 9.831 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr9_+_3015654 9.778 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr9_+_3025417 9.600 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr2_-_98667264 9.553 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr2_+_98662227 9.507 ENSMUST00000099684.3
Gm10801
predicted gene 10801
chr14_-_19418930 8.254 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3018753 8.240 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chrX_+_103422010 5.846 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr19_-_5796924 3.816 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr19_-_5797410 2.475 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_+_43508118 2.420 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_116972609 2.419 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr16_+_43364145 2.073 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr9_+_67840386 2.049 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr13_+_16014457 2.017 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr16_+_43503607 1.936 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr1_+_15312452 1.907 ENSMUST00000171715.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chrX_-_143933089 1.872 ENSMUST00000087313.3
Dcx
doublecortin
chr18_+_34247685 1.797 ENSMUST00000066133.6
Apc
adenomatosis polyposis coli
chr15_-_12592556 1.787 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr6_-_59024340 1.704 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr17_-_91088726 1.670 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr1_+_15287259 1.617 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr1_-_63114516 1.614 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr5_+_66968961 1.575 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr4_-_82705735 1.559 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr9_-_75597643 1.553 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr17_+_6106464 1.519 ENSMUST00000142030.1
Tulp4
tubby like protein 4
chr4_-_82505707 1.507 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr17_+_35841668 1.481 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr12_-_75177325 1.471 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr1_-_133701881 1.457 ENSMUST00000167348.1
Gm17678
predicted gene, 17678
chr5_+_66968559 1.445 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr17_-_81649607 1.404 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr17_+_91088493 1.399 ENSMUST00000095183.1
Gm10308
predicted gene 10308
chr5_+_3928033 1.393 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr11_-_86257553 1.379 ENSMUST00000132024.1
ENSMUST00000139285.1
Ints2

integrator complex subunit 2

chr2_+_112265809 1.339 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr3_-_80802789 1.335 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr6_+_28215555 1.291 ENSMUST00000143099.1
ENSMUST00000143551.1
6530409C15Rik

RIKEN cDNA 6530409C15 gene

chr2_-_45110241 1.284 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_144209471 1.270 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr1_+_34005872 1.242 ENSMUST00000182296.1
Dst
dystonin
chr5_+_3343893 1.230 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr15_+_90224293 1.225 ENSMUST00000100309.1
Alg10b
asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
chr6_+_86849488 1.223 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr13_+_44731281 1.209 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr14_+_75955003 1.205 ENSMUST00000050120.2
Kctd4
potassium channel tetramerisation domain containing 4
chr4_+_54945038 1.202 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr11_+_31872100 1.202 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr15_-_98567630 1.200 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr7_+_49246812 1.194 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr11_-_62458508 1.189 ENSMUST00000141447.1
Ncor1
nuclear receptor co-repressor 1
chr1_+_60181495 1.187 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chr7_-_4778141 1.176 ENSMUST00000094892.5
Il11
interleukin 11
chr6_-_144209558 1.159 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr9_+_40686002 1.143 ENSMUST00000034522.7
Clmp
CXADR-like membrane protein
chr3_+_122729158 1.139 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr2_+_68861564 1.124 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr3_+_7612702 1.123 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr9_-_96719404 1.119 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr4_+_48049080 1.097 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr3_-_58885212 1.096 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
Clrn1


clarin 1


chr1_-_190170178 1.082 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr11_+_75468040 1.080 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr9_+_35423582 1.071 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr8_-_67818218 1.071 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr6_-_144209448 1.069 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr9_-_95750335 1.066 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr14_-_64949632 1.057 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr3_-_148989316 1.041 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr1_-_56969827 1.039 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr3_-_158562199 1.038 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr12_-_102878406 1.024 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr1_-_82291370 1.019 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr14_-_60086832 1.007 ENSMUST00000080368.5
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr18_+_37294840 1.002 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr14_+_60378242 0.998 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr17_+_88626569 0.995 ENSMUST00000150023.1
Ston1
stonin 1
chr1_-_56969864 0.994 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_28263563 0.982 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr5_-_62765618 0.979 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_127780461 0.971 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr5_+_89027959 0.968 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr2_-_140671440 0.966 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr7_+_24176152 0.951 ENSMUST00000086010.5
Zfp114
zinc finger protein 114
chr13_+_49653297 0.942 ENSMUST00000021824.7
Nol8
nucleolar protein 8
chr3_-_116807733 0.935 ENSMUST00000159670.1
Agl
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr1_-_64121389 0.921 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_-_44234014 0.917 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr10_+_79997463 0.915 ENSMUST00000171637.1
ENSMUST00000043866.7
Abca7

ATP-binding cassette, sub-family A (ABC1), member 7

chr4_-_82505749 0.910 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_3938354 0.908 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr3_+_88965812 0.896 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_-_60566708 0.893 ENSMUST00000027168.5
ENSMUST00000090293.4
ENSMUST00000140485.1
Raph1


Ras association (RalGDS/AF-6) and pleckstrin homology domains 1


chr18_+_69344503 0.889 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr1_+_81077274 0.888 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr5_-_70842617 0.885 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr10_+_89873497 0.884 ENSMUST00000183156.1
ENSMUST00000182936.1
ENSMUST00000099368.4
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr8_-_67818284 0.882 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_15049395 0.874 ENSMUST00000017562.6
Arl5b
ADP-ribosylation factor-like 5B
chr2_-_120539852 0.860 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr5_-_106696819 0.856 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr2_-_18048784 0.854 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr3_+_90341654 0.841 ENSMUST00000049382.4
Gatad2b
GATA zinc finger domain containing 2B
chr13_-_41847626 0.841 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr3_-_97868242 0.834 ENSMUST00000107038.3
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr7_+_83584910 0.831 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr10_+_29143996 0.830 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr18_+_36939178 0.824 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr18_+_69593361 0.821 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr3_-_51560816 0.820 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr6_+_38433913 0.820 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chr16_+_41532851 0.816 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr10_-_95415283 0.816 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr3_-_108402589 0.812 ENSMUST00000147565.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr11_+_77348272 0.806 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr1_-_186705980 0.800 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr1_+_187215501 0.798 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
Gpatch2



G patch domain containing 2



chr14_-_101609033 0.795 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr17_+_6270475 0.791 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr4_+_32657107 0.791 ENSMUST00000071642.4
ENSMUST00000178134.1
Mdn1

midasin homolog (yeast)

chr1_+_81077204 0.790 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr4_-_91371946 0.784 ENSMUST00000176362.1
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_-_19264959 0.779 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr1_-_162740350 0.778 ENSMUST00000182331.1
ENSMUST00000183011.1
ENSMUST00000182593.1
ENSMUST00000182149.1
Prrc2c



proline-rich coiled-coil 2C



chr3_+_38886940 0.776 ENSMUST00000061260.7
Fat4
FAT tumor suppressor homolog 4 (Drosophila)
chr9_+_53537021 0.774 ENSMUST00000035850.7
Npat
nuclear protein in the AT region
chr7_+_27692502 0.773 ENSMUST00000076421.6
C030039L03Rik
RIKEN cDNA C030039L03 gene
chr5_+_89028035 0.773 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr8_-_99416397 0.769 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
Cdh8




cadherin 8




chr1_-_45503282 0.768 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr16_+_94425083 0.767 ENSMUST00000141176.1
Ttc3
tetratricopeptide repeat domain 3
chr11_-_47379405 0.758 ENSMUST00000077221.5
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr9_-_53706211 0.756 ENSMUST00000068449.3
Rab39
RAB39, member RAS oncogene family
chr5_+_105731755 0.755 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr10_-_27616895 0.755 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr17_-_6621267 0.753 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr5_-_114273702 0.751 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr3_-_127225917 0.751 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr3_-_116968969 0.749 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr4_-_110286581 0.747 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_+_24943144 0.734 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr16_-_34263179 0.731 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr14_-_64949838 0.727 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
Hmbox1





homeobox containing 1





chr1_+_55237177 0.722 ENSMUST00000061334.8
Mars2
methionine-tRNA synthetase 2 (mitochondrial)
chr5_-_148995147 0.718 ENSMUST00000147473.1
Katnal1
katanin p60 subunit A-like 1
chr2_+_82053222 0.716 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr1_-_190170671 0.715 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr6_+_149408973 0.710 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr4_+_128846163 0.709 ENSMUST00000138291.1
Gm12968
predicted gene 12968
chr19_-_56822161 0.703 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr12_+_71048338 0.701 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr9_+_118478182 0.698 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr12_-_54999102 0.698 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr5_+_3571664 0.694 ENSMUST00000008451.5
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chr3_-_127225847 0.687 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr4_-_44168252 0.669 ENSMUST00000145760.1
ENSMUST00000128426.1
Rnf38

ring finger protein 38

chr11_-_70656467 0.661 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr11_+_86484647 0.659 ENSMUST00000020827.6
Rnft1
ring finger protein, transmembrane 1
chr17_+_35841491 0.656 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr3_-_116968827 0.654 ENSMUST00000119557.1
Palmd
palmdelphin
chr11_+_106789235 0.650 ENSMUST00000103068.3
ENSMUST00000018516.4
Cep95

centrosomal protein 95

chr1_-_162740540 0.650 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr1_+_170214826 0.649 ENSMUST00000159201.1
ENSMUST00000055830.1
4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr3_+_32397671 0.649 ENSMUST00000108243.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr12_+_29528382 0.644 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr10_-_17947997 0.642 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr1_-_132067956 0.642 ENSMUST00000144548.2
ENSMUST00000112370.2
ENSMUST00000112365.2
Mfsd4


major facilitator superfamily domain containing 4


chr10_+_58255465 0.637 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr10_-_105574435 0.637 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr2_+_180042496 0.631 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr16_-_50432340 0.629 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr1_+_180111339 0.628 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr11_-_86257518 0.623 ENSMUST00000136469.1
ENSMUST00000018212.6
Ints2

integrator complex subunit 2

chr6_-_59024470 0.621 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr7_-_14562171 0.617 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr5_+_15934762 0.615 ENSMUST00000115281.2
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr11_-_22001605 0.613 ENSMUST00000006071.7
Otx1
orthodenticle homolog 1 (Drosophila)
chr14_+_67716262 0.613 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr10_-_29144194 0.612 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr18_+_37333853 0.612 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr2_-_52558539 0.604 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr1_+_19103022 0.603 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr16_+_17451981 0.603 ENSMUST00000006293.3
Crkl
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr17_-_78985428 0.602 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr18_-_35215008 0.602 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr1_+_194619815 0.601 ENSMUST00000027952.5
Plxna2
plexin A2
chr16_-_91618986 0.601 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr3_-_84259812 0.601 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0035063 nuclear speck organization(GO:0035063)
1.0 4.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 1.8 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.6 0.6 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.4 1.8 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.4 1.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.4 1.7 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.4 2.0 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 3.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.4 1.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.4 1.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 1.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.3 1.0 GO:0072554 blood vessel lumenization(GO:0072554) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.3 0.9 GO:1901608 dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.3 1.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 0.6 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.3 1.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.3 1.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.3 2.0 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.3 1.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 0.8 GO:0003289 endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289) negative regulation of alkaline phosphatase activity(GO:0010693) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.3 1.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.2 0.7 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.2 0.5 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 0.6 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 0.4 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 0.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 1.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 1.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 0.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 0.8 GO:0009405 pathogenesis(GO:0009405)
0.2 0.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 1.3 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 0.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.9 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.2 1.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 0.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 7.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 1.4 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.2 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 0.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.9 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 0.6 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 2.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 1.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 1.1 GO:0046541 saliva secretion(GO:0046541)
0.1 1.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.4 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.8 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.1 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.6 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0034140 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.3 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.3 GO:0030046 meiotic chromosome movement towards spindle pole(GO:0016344) parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 2.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.5 GO:0035989 tendon development(GO:0035989)
0.1 2.1 GO:0002076 osteoblast development(GO:0002076)
0.1 0.8 GO:0060174 limb bud formation(GO:0060174)
0.1 0.3 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.3 GO:2000468 regulation of protein autoubiquitination(GO:1902498) regulation of peroxidase activity(GO:2000468)
0.1 0.9 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 2.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 0.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.4 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.0 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.3 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.4 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.1 0.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.8 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0017085 response to insecticide(GO:0017085)
0.1 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.2 GO:0006868 glutamine transport(GO:0006868)
0.1 0.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
0.1 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 1.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0097151 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 1.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0072172 heparin metabolic process(GO:0030202) ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.0 0.1 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.8 GO:0048536 spleen development(GO:0048536)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.4 GO:0031100 organ regeneration(GO:0031100)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.6 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 1.0 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.2 GO:0022410 circadian sleep/wake cycle process(GO:0022410) circadian sleep/wake cycle(GO:0042745) regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.0 GO:0071865 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) apoptotic process in bone marrow(GO:0071839) regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.4 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.7 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.0 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.4 GO:0044307 dendritic branch(GO:0044307)
0.3 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.2 GO:0031673 H zone(GO:0031673)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.7 GO:0008623 CHRAC(GO:0008623)
0.2 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 2.1 GO:0032039 integrator complex(GO:0032039)
0.1 1.2 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.1 3.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 1.1 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 3.5 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.0 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0033655 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 3.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 1.8 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:1990462 omegasome(GO:1990462)
0.0 3.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 1.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.3 0.9 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.7 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 3.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.2 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.8 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.6 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.4 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.8 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0030553 cGMP binding(GO:0030553)
0.1 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 4.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.5 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.1 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 3.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 0.6 PID_ALK2_PATHWAY ALK2 signaling events
0.0 2.0 PID_ATM_PATHWAY ATM pathway
0.0 1.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 1.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.4 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.6 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.0 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 4.2 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.4 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.6 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 2.1 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 1.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 4.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.2 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.3 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.0 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)