Motif ID: Nfil3_Tef

Z-value: 1.622

Transcription factors associated with Nfil3_Tef:

Gene SymbolEntrez IDGene Name
Nfil3 ENSMUSG00000056749.7 Nfil3
Tef ENSMUSG00000022389.8 Tef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfil3mm10_v2_chr13_-_52981027_529810830.437.2e-03Click!
Tefmm10_v2_chr15_+_81811414_818114910.344.2e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nfil3_Tef

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_22439570 15.937 ENSMUST00000170393.1
Etv5
ets variant gene 5
chrX_-_51681703 11.032 ENSMUST00000088172.5
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chrX_-_51681856 11.011 ENSMUST00000114871.1
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr13_+_76579670 9.563 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr11_-_101785252 9.336 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr14_+_65971049 8.796 ENSMUST00000128539.1
Clu
clusterin
chr14_+_65970804 8.679 ENSMUST00000138191.1
Clu
clusterin
chr12_+_74288735 8.622 ENSMUST00000095617.1
1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr2_-_25469742 8.478 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr9_-_40346290 8.382 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr2_-_25470031 7.911 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr5_+_117841839 7.724 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr14_+_65970610 7.579 ENSMUST00000127387.1
Clu
clusterin
chr1_-_91459254 7.036 ENSMUST00000069620.8
Per2
period circadian clock 2
chr3_+_141465564 6.590 ENSMUST00000106236.2
ENSMUST00000075282.3
Unc5c

unc-5 homolog C (C. elegans)

chr9_-_21037775 6.482 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr15_-_8710734 6.387 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_65971164 6.029 ENSMUST00000144619.1
Clu
clusterin
chr17_+_69156791 5.893 ENSMUST00000112680.1
ENSMUST00000080208.5
Epb4.1l3

erythrocyte protein band 4.1-like 3

chr13_+_16011851 5.859 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr5_+_66968961 5.378 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr3_+_84952146 5.362 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr15_-_8710409 5.327 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr16_-_76373827 5.033 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr7_+_92062392 4.957 ENSMUST00000098308.2
Dlg2
discs, large homolog 2 (Drosophila)
chr4_+_85205417 4.933 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr14_+_48120841 4.885 ENSMUST00000073150.4
Peli2
pellino 2
chr18_+_23803962 4.862 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr4_+_47208005 4.853 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr10_-_125308809 4.816 ENSMUST00000105257.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr4_+_101419696 4.801 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr6_-_55681257 4.800 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr7_-_103827922 4.792 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chrX_-_162565514 4.225 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr6_-_99044414 4.195 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr2_+_131909928 4.180 ENSMUST00000091288.6
Prnp
prion protein
chr3_+_51559973 4.057 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr2_+_131909951 4.020 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr7_-_110862944 4.018 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_144175513 3.953 ENSMUST00000105900.1
Shank2
SH3/ankyrin domain gene 2
chr13_-_41079628 3.838 ENSMUST00000165087.1
ENSMUST00000070193.6
Mak

male germ cell-associated kinase

chr18_+_37320374 3.790 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr8_-_60954726 3.551 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr4_+_85205120 3.531 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr15_-_33687840 3.508 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr2_-_131042682 3.443 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr3_-_113574758 3.403 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr13_+_42866247 3.383 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr15_-_37007382 3.340 ENSMUST00000078976.7
Zfp706
zinc finger protein 706
chr6_+_17463749 3.307 ENSMUST00000115443.1
Met
met proto-oncogene
chr4_+_101507947 3.251 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr16_+_45093611 2.823 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr4_+_101507855 2.818 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_45592569 2.806 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr14_-_18893376 2.789 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr6_-_99028874 2.769 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr10_-_64090241 2.738 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_+_19004047 2.730 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr10_-_126901315 2.726 ENSMUST00000026504.5
ENSMUST00000168520.1
Xrcc6bp1

XRCC6 binding protein 1

chr9_+_109931774 2.714 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr15_+_38933142 2.703 ENSMUST00000163313.1
Baalc
brain and acute leukemia, cytoplasmic
chr17_-_24073479 2.685 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr7_+_96211656 2.640 ENSMUST00000107165.1
Tenm4
teneurin transmembrane protein 4
chr4_-_119538769 2.620 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr19_+_23141183 2.596 ENSMUST00000036884.1
Klf9
Kruppel-like factor 9
chr1_-_140183404 2.567 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr1_-_58586191 2.506 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr16_+_78930940 2.450 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr10_-_78464853 2.434 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr12_+_85599047 2.434 ENSMUST00000177587.1
Jdp2
Jun dimerization protein 2
chr10_-_78464969 2.367 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr8_+_46490968 2.356 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr17_-_45592485 2.354 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr3_+_51559757 2.345 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr14_-_18239053 2.201 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr7_-_29125142 2.152 ENSMUST00000179893.1
ENSMUST00000032813.9
Ryr1

ryanodine receptor 1, skeletal muscle

chr1_-_134955908 2.089 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr4_-_121017201 2.075 ENSMUST00000043200.7
Smap2
small ArfGAP 2
chr10_-_77418230 2.055 ENSMUST00000020496.7
ENSMUST00000098374.2
ENSMUST00000105406.1
Adarb1


adenosine deaminase, RNA-specific, B1


chr9_+_40269273 2.018 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr5_+_135009152 2.017 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr4_-_134853294 2.013 ENSMUST00000030628.8
Tmem57
transmembrane protein 57
chrX_-_103483205 2.007 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr9_+_109931458 2.005 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr16_+_3884629 1.966 ENSMUST00000176233.1
Gm20695
predicted gene 20695
chr12_+_85599388 1.949 ENSMUST00000050687.6
Jdp2
Jun dimerization protein 2
chr19_-_8723356 1.912 ENSMUST00000170157.1
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr9_+_40269202 1.832 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr11_-_106216318 1.824 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr13_+_63014934 1.812 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr15_+_7129557 1.756 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr16_+_92292380 1.727 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr1_-_140183283 1.714 ENSMUST00000111977.1
Cfh
complement component factor h
chr2_-_132111440 1.593 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr10_-_31445921 1.563 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr9_+_109931863 1.562 ENSMUST00000165876.1
Map4
microtubule-associated protein 4
chr5_-_122988533 1.551 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr3_-_146770218 1.525 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_-_150003130 1.514 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr11_-_79530569 1.496 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr4_+_41941572 1.444 ENSMUST00000108028.2
ENSMUST00000153997.1
Gm20878

predicted gene, 20878

chr13_-_52981027 1.430 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr2_-_60284292 1.406 ENSMUST00000028356.8
ENSMUST00000074606.4
Cd302

CD302 antigen

chr9_+_21936986 1.373 ENSMUST00000046371.6
BC018242
cDNA sequence BC018242
chr17_-_80290476 1.333 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr3_-_146770603 1.320 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_49504774 1.294 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_+_101419277 1.260 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr15_-_38519227 1.251 ENSMUST00000110328.1
ENSMUST00000110329.1
ENSMUST00000065308.5
Azin1


antizyme inhibitor 1


chr7_+_28825202 1.247 ENSMUST00000066264.6
Ech1
enoyl coenzyme A hydratase 1, peroxisomal
chr10_+_81176631 1.229 ENSMUST00000047864.9
Eef2
eukaryotic translation elongation factor 2
chr13_-_67451585 1.208 ENSMUST00000057241.8
ENSMUST00000075255.5
Zfp874a

zinc finger protein 874a

chr14_+_75136326 1.185 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr17_+_8283762 1.173 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
Mpc1


mitochondrial pyruvate carrier 1


chr9_+_110344185 1.140 ENSMUST00000142100.1
Scap
SREBF chaperone
chr9_-_110624361 1.129 ENSMUST00000035069.9
Nradd
neurotrophin receptor associated death domain
chr4_+_41942037 1.114 ENSMUST00000181518.1
Gm20878
predicted gene, 20878
chr4_+_43493345 1.108 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr7_-_127393604 1.101 ENSMUST00000165495.1
ENSMUST00000106303.2
ENSMUST00000074249.6
E430018J23Rik


RIKEN cDNA E430018J23 gene


chr14_-_55635602 1.100 ENSMUST00000047131.9
Ipo4
importin 4
chr9_+_94669876 1.096 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_+_96181151 1.088 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr18_-_36726730 1.067 ENSMUST00000061829.6
Cd14
CD14 antigen
chr4_-_41774097 1.066 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
Ccl27a



chemokine (C-C motif) ligand 27A



chr3_+_90341654 1.042 ENSMUST00000049382.4
Gatad2b
GATA zinc finger domain containing 2B
chr6_+_121183667 1.037 ENSMUST00000118234.1
ENSMUST00000088561.3
ENSMUST00000137432.1
ENSMUST00000120066.1
Pex26



peroxisomal biogenesis factor 26



chr18_+_37742088 1.030 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr10_+_127421208 1.029 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr8_+_22060712 1.017 ENSMUST00000072572.6
ENSMUST00000110737.2
ENSMUST00000131624.1
Alg11


asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)


chr1_-_9299238 0.992 ENSMUST00000140295.1
Sntg1
syntrophin, gamma 1
chr10_+_90071095 0.985 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr8_-_109251698 0.982 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chrX_-_74428871 0.974 ENSMUST00000143521.1
G6pdx
glucose-6-phosphate dehydrogenase X-linked
chr5_+_24364804 0.973 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr4_+_152039315 0.961 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr1_-_38129618 0.947 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr5_-_36695969 0.939 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr17_+_26715644 0.921 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr7_+_29238434 0.916 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_-_38898084 0.881 ENSMUST00000027249.6
Chst10
carbohydrate sulfotransferase 10
chr5_-_92328068 0.878 ENSMUST00000113093.3
Cxcl9
chemokine (C-X-C motif) ligand 9
chr9_+_121366958 0.865 ENSMUST00000045903.6
Trak1
trafficking protein, kinesin binding 1
chr3_+_88965812 0.836 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr10_-_64090265 0.825 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_-_133277730 0.805 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr1_+_171840607 0.798 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr10_+_77978524 0.791 ENSMUST00000105397.3
ENSMUST00000105398.1
1810043G02Rik

RIKEN cDNA 1810043G02 gene

chr10_-_78185102 0.779 ENSMUST00000042556.9
Pwp2
PWP2 periodic tryptophan protein homolog (yeast)
chr2_+_129065934 0.768 ENSMUST00000035812.7
Ttl
tubulin tyrosine ligase
chr3_+_138443085 0.757 ENSMUST00000005964.2
Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
chr2_-_114201416 0.757 ENSMUST00000050668.3
Zfp770
zinc finger protein 770
chr6_-_119467210 0.753 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr8_-_91134027 0.729 ENSMUST00000125257.1
Aktip
thymoma viral proto-oncogene 1 interacting protein
chr1_+_21218575 0.718 ENSMUST00000027065.5
ENSMUST00000027064.7
Tmem14a

transmembrane protein 14A

chr6_-_87809757 0.712 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr9_-_78443204 0.711 ENSMUST00000070742.7
ENSMUST00000034898.7
Mb21d1

Mab-21 domain containing 1

chr10_+_127421124 0.710 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr7_+_29238323 0.697 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yif1b


Yip1 interacting factor homolog B (S. cerevisiae)


chr16_-_89818338 0.668 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr7_+_27447978 0.666 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr11_-_71004387 0.664 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr3_+_88579602 0.654 ENSMUST00000035785.7
Ssr2
signal sequence receptor, beta
chr12_-_87200200 0.644 ENSMUST00000037418.5
Tmed8
transmembrane emp24 domain containing 8
chr11_-_116086929 0.623 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr2_+_155751117 0.605 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr4_+_42735545 0.587 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr11_-_6200411 0.585 ENSMUST00000066496.3
Nudcd3
NudC domain containing 3
chr1_-_161034794 0.583 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37


zinc finger and BTB domain containing 37


chr14_-_45388772 0.566 ENSMUST00000046191.7
Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr5_+_66676098 0.565 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr7_+_100607410 0.561 ENSMUST00000107048.1
ENSMUST00000032946.3
Rab6a

RAB6A, member RAS oncogene family

chr2_+_129800451 0.534 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35

serine/threonine kinase 35

chr4_+_19575139 0.523 ENSMUST00000108253.1
ENSMUST00000029888.3
Rmdn1

regulator of microtubule dynamics 1

chr2_-_66410064 0.505 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr15_+_37233036 0.504 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2


grainyhead-like 2 (Drosophila)


chr19_-_59943000 0.499 ENSMUST00000170819.1
Rab11fip2
RAB11 family interacting protein 2 (class I)
chr6_+_72347301 0.494 ENSMUST00000077783.3
0610030E20Rik
RIKEN cDNA 0610030E20 gene
chr2_-_79908428 0.482 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr10_+_62980233 0.477 ENSMUST00000131718.1
ENSMUST00000119567.1
ENSMUST00000122231.1
Rufy2


RUN and FYVE domain-containing 2


chr10_+_53337686 0.468 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr2_-_177324307 0.456 ENSMUST00000108959.2
Gm14412
predicted gene 14412
chr2_-_131328982 0.455 ENSMUST00000110194.1
Rnf24
ring finger protein 24
chr15_+_68928414 0.423 ENSMUST00000022954.6
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr13_-_96471160 0.420 ENSMUST00000055607.5
ENSMUST00000181613.2
Ankdd1b

ankyrin repeat and death domain containing 1B

chr2_-_168206875 0.409 ENSMUST00000057793.4
Adnp
activity-dependent neuroprotective protein
chr13_+_63015167 0.397 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr14_-_103099499 0.363 ENSMUST00000022720.8
Fbxl3
F-box and leucine-rich repeat protein 3
chr10_+_75212065 0.346 ENSMUST00000105421.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr18_+_32837225 0.332 ENSMUST00000166214.1
ENSMUST00000053663.9
Wdr36

WD repeat domain 36

chr5_-_147894804 0.331 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chrX_-_94212638 0.330 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr11_+_6415443 0.312 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr13_-_25270076 0.312 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr9_-_71163224 0.309 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr3_-_88762244 0.308 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr9_+_53850243 0.306 ENSMUST00000048485.5
Sln
sarcolipin
chr10_+_67185730 0.256 ENSMUST00000173689.1
Jmjd1c
jumonji domain containing 1C
chr7_-_42578588 0.247 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr19_-_42431778 0.236 ENSMUST00000048630.6
Crtac1
cartilage acidic protein 1
chr13_-_21479441 0.229 ENSMUST00000076238.3
Gm10065
predicted gene 10065

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 31.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
3.7 22.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
3.6 25.3 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
3.3 16.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
2.9 11.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.6 7.7 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
2.3 7.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
1.7 5.0 GO:0001543 ovarian follicle rupture(GO:0001543)
1.6 4.8 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.5 6.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.4 10.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.4 4.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.2 8.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.2 3.6 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.2 5.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
1.1 5.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.0 6.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.8 6.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.7 5.2 GO:0015862 uridine transport(GO:0015862)
0.7 4.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 7.0 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.7 2.1 GO:0061744 motor behavior(GO:0061744)
0.7 2.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.7 3.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.7 2.6 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.6 1.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 2.8 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.5 1.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.5 1.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.5 1.0 GO:0002034 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.5 1.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.5 3.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.4 4.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.4 2.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 3.9 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.4 4.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.4 3.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 1.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 1.1 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.4 5.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 2.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 6.1 GO:0046033 AMP metabolic process(GO:0046033)
0.3 1.7 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.3 0.8 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.3 2.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 0.8 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.2 0.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 0.7 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.7 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 4.8 GO:0021542 dentate gyrus development(GO:0021542)
0.2 2.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.9 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 1.8 GO:0006983 ER overload response(GO:0006983)
0.2 1.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 4.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.2 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.2 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 4.0 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.8 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 0.6 GO:0006048 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 2.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.3 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 1.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 3.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.7 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.9 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 2.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.7 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 0.5 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 0.2 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 1.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 1.1 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 8.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.0 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 2.9 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 4.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) negative regulation of prostatic bud formation(GO:0060686)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.9 GO:0007616 long-term memory(GO:0007616)
0.0 3.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.1 GO:0071472 cellular response to salt stress(GO:0071472)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 2.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0032402 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0 0.0 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.5 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 1.4 GO:0006909 phagocytosis(GO:0006909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 31.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
2.0 5.9 GO:0043512 inhibin A complex(GO:0043512)
1.3 5.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.2 4.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 7.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5 2.2 GO:0014802 terminal cisterna(GO:0014802)
0.4 4.0 GO:0005883 neurofilament(GO:0005883)
0.4 3.6 GO:0042581 specific granule(GO:0042581)
0.3 3.8 GO:0097542 ciliary tip(GO:0097542)
0.3 4.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 5.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.0 GO:0000805 X chromosome(GO:0000805)
0.2 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 13.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.1 2.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 21.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.9 GO:0005581 collagen trimer(GO:0005581)
0.1 6.3 GO:0005930 axoneme(GO:0005930)
0.1 5.4 GO:0016234 inclusion body(GO:0016234)
0.1 4.4 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 5.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.1 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 8.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 35.8 GO:0070062 extracellular exosome(GO:0070062)
0.0 8.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 10.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 5.2 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 22.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
4.1 16.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.9 8.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
2.0 6.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.6 4.8 GO:0031403 lithium ion binding(GO:0031403)
1.5 9.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.5 6.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.3 31.1 GO:0051787 misfolded protein binding(GO:0051787)
1.2 4.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
1.1 3.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.1 3.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
1.1 6.6 GO:0005042 netrin receptor activity(GO:0005042)
1.1 5.4 GO:0050816 phosphothreonine binding(GO:0050816)
1.1 4.3 GO:0001851 complement component C3b binding(GO:0001851)
1.0 4.2 GO:1903135 cupric ion binding(GO:1903135)
1.0 5.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.9 3.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.8 3.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.8 2.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.7 2.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.6 2.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.6 1.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.6 3.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5 1.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.5 2.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5 2.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.4 7.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.3 GO:0070052 collagen V binding(GO:0070052)
0.4 2.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 6.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 1.1 GO:0071723 lipopeptide binding(GO:0071723)
0.3 1.7 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3 1.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.3 2.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.3 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.3 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 1.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 5.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 5.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 0.7 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 5.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 1.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 4.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 3.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 17.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 6.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 3.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 6.4 GO:0008017 microtubule binding(GO:0008017)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 10.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 1.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 6.2 GO:0008289 lipid binding(GO:0008289)
0.0 2.5 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.4 31.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.4 7.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 5.4 PID_MYC_PATHWAY C-MYC pathway
0.2 4.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 8.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.2 5.9 PID_ALK1_PATHWAY ALK1 signaling events
0.2 6.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 8.5 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 9.3 PID_LKB1_PATHWAY LKB1 signaling events
0.1 5.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 2.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 1.0 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.1 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 3.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.9 4.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.6 22.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 4.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 8.5 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 4.0 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 31.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 8.7 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 4.0 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 1.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 6.1 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 11.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 7.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 7.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 5.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 6.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 4.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 3.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.6 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 2.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins