Motif ID: Nkx2-2

Z-value: 1.594


Transcription factors associated with Nkx2-2:

Gene SymbolEntrez IDGene Name
Nkx2-2 ENSMUSG00000027434.10 Nkx2-2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-2mm10_v2_chr2_-_147186389_147186413-0.038.4e-01Click!


Activity profile for motif Nkx2-2.

activity profile for motif Nkx2-2


Sorted Z-values histogram for motif Nkx2-2

Sorted Z-values for motif Nkx2-2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_5218516 8.441 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr1_-_135688094 7.191 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr14_-_19418930 6.481 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_72438534 6.325 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr9_+_3018753 6.047 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_72438519 6.037 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr4_+_46039202 5.944 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chr9_+_3017408 5.752 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3034599 5.630 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3015654 5.600 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr11_+_78301529 5.530 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr2_-_140170528 5.489 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_+_3005125 5.479 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3025417 5.453 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr2_-_84775388 4.995 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775420 4.963 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_114013619 4.933 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr4_+_59626189 4.917 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr2_+_62664279 4.873 ENSMUST00000028257.2
Gca
grancalcin
chr1_-_166002613 4.540 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr5_-_69592274 4.271 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chrX_+_106027259 4.253 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chrX_+_106027300 3.660 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr7_-_123369870 3.616 ENSMUST00000106442.2
ENSMUST00000098060.3
ENSMUST00000167309.1
Arhgap17


Rho GTPase activating protein 17


chr9_-_96719549 3.613 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr3_+_5218546 3.512 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr1_+_82339049 3.477 ENSMUST00000140020.1
Rhbdd1
rhomboid domain containing 1
chr3_-_49757257 3.397 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr17_+_43568641 3.349 ENSMUST00000169694.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_+_102706356 3.311 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr19_-_5796924 3.307 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_16527364 3.303 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr13_-_41487306 3.293 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr3_-_84304762 3.265 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr6_+_137754529 3.233 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chrX_+_9885622 3.139 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr10_+_88091070 3.054 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr13_+_51645232 3.040 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr6_+_14901344 3.028 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr15_-_10470490 3.019 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr13_+_33964659 2.984 ENSMUST00000021843.5
ENSMUST00000058978.7
Nqo2

NAD(P)H dehydrogenase, quinone 2

chr8_+_69300776 2.878 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr9_-_96719404 2.806 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr6_-_56369625 2.761 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c


phosphodiesterase 1C


chr15_+_75704280 2.636 ENSMUST00000121137.1
ENSMUST00000023244.5
Rhpn1

rhophilin, Rho GTPase binding protein 1

chr5_+_110839973 2.586 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr2_+_23069210 2.569 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr12_+_59129720 2.480 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr3_+_76075583 2.474 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_+_52072823 2.449 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr17_+_43568475 2.399 ENSMUST00000167418.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr13_-_85127514 2.308 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr6_-_108185552 2.304 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr3_+_14533817 2.223 ENSMUST00000169079.1
ENSMUST00000091325.3
Lrrcc1

leucine rich repeat and coiled-coil domain containing 1

chr3_+_81932601 2.189 ENSMUST00000029649.2
Ctso
cathepsin O
chr2_+_174076296 2.186 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
Stx16


syntaxin 16


chr8_+_41239718 2.162 ENSMUST00000045218.7
Pcm1
pericentriolar material 1
chr13_-_103764502 2.134 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr13_+_51846673 2.126 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr18_+_32163073 2.060 ENSMUST00000096575.3
Map3k2
mitogen-activated protein kinase kinase kinase 2
chr14_-_72602945 2.018 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chrM_+_11734 1.991 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr3_+_138143429 1.954 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr3_+_138143846 1.945 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr14_+_47663756 1.937 ENSMUST00000022391.7
Ktn1
kinectin 1
chr19_-_29753600 1.848 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr4_-_45530330 1.821 ENSMUST00000061986.5
Shb
src homology 2 domain-containing transforming protein B
chr2_+_32535724 1.814 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr5_-_30073554 1.769 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr3_+_52268337 1.746 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr13_+_23756937 1.727 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr12_-_100899436 1.726 ENSMUST00000053668.3
Gpr68
G protein-coupled receptor 68
chr3_+_76593550 1.716 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr1_-_152386589 1.697 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr1_-_139377094 1.696 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr2_-_26237368 1.655 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr6_-_120357440 1.594 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chrX_+_75382384 1.567 ENSMUST00000033541.4
Fundc2
FUN14 domain containing 2
chr7_-_6011010 1.551 ENSMUST00000086338.1
Vmn1r65
vomeronasal 1 receptor 65
chr8_+_40354303 1.541 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr2_-_77946331 1.523 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr2_-_77946375 1.519 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr6_-_120357422 1.512 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr9_+_74976096 1.396 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr9_-_105395237 1.389 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr3_+_138143483 1.386 ENSMUST00000162864.1
Trmt10a
tRNA methyltransferase 10A
chr1_-_152386675 1.384 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr3_+_138143799 1.372 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chr12_+_32953874 1.344 ENSMUST00000076698.5
Sypl
synaptophysin-like protein
chr9_-_8004585 1.337 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr1_-_88008520 1.312 ENSMUST00000040783.4
Usp40
ubiquitin specific peptidase 40
chr2_+_3704787 1.299 ENSMUST00000115054.2
Fam107b
family with sequence similarity 107, member B
chr17_-_15564322 1.293 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chrX_+_68821093 1.266 ENSMUST00000096420.2
Gm14698
predicted gene 14698
chr3_+_138143888 1.251 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr2_+_83644435 1.242 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr14_-_59395381 1.231 ENSMUST00000166912.2
Phf11c
PHD finger protein 11C
chr4_-_45532470 1.226 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr9_+_35559460 1.208 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr12_+_105784694 1.202 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chr6_-_120357342 1.194 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr3_+_30792876 1.178 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chrX_+_101274023 1.165 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr10_+_19951055 1.161 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr4_+_116558056 1.159 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr6_-_70792155 1.145 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr4_+_115563649 1.144 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
Cyp4a31



cytochrome P450, family 4, subfamily a, polypeptide 31



chr2_-_127444524 1.122 ENSMUST00000028848.3
Fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chrX_+_164269371 1.082 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr18_-_6241486 1.081 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr11_-_57518596 1.065 ENSMUST00000108850.1
ENSMUST00000020831.6
Fam114a2

family with sequence similarity 114, member A2

chr10_-_12861735 1.040 ENSMUST00000076817.4
Utrn
utrophin
chr18_-_6241470 1.033 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr19_-_40402267 1.029 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr11_+_57518657 1.028 ENSMUST00000108849.1
ENSMUST00000020830.7
Mfap3

microfibrillar-associated protein 3

chr2_+_69897255 1.013 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr14_-_54686060 0.973 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr1_-_176807124 0.972 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr13_-_29855630 0.969 ENSMUST00000091674.5
ENSMUST00000006353.7
Cdkal1

CDK5 regulatory subunit associated protein 1-like 1

chr12_+_111039334 0.963 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr5_-_123140135 0.961 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr18_-_84951477 0.944 ENSMUST00000025547.2
Timm21
tranlocase of inner mitochondrial membrane 21
chr15_-_58034289 0.924 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr1_+_179960472 0.918 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_43058939 0.910 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chr6_+_8520008 0.891 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr1_-_139377041 0.880 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr9_-_106891401 0.847 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr17_-_32822200 0.845 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr10_+_126978690 0.839 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_+_3596066 0.811 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr7_+_29768552 0.801 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr17_-_23771543 0.795 ENSMUST00000086325.5
Flywch1
FLYWCH-type zinc finger 1
chr13_+_38036989 0.779 ENSMUST00000021866.8
Riok1
RIO kinase 1 (yeast)
chr14_+_24490678 0.763 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr6_+_3993776 0.733 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr11_-_69900949 0.732 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr3_+_62419668 0.729 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr4_-_129640959 0.727 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
Txlna


taxilin alpha


chrX_+_73673150 0.720 ENSMUST00000033752.7
ENSMUST00000114467.2
Slc6a8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr10_+_106470281 0.710 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr6_-_3494587 0.702 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr7_-_80403315 0.694 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr11_-_69900886 0.682 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr11_-_69900930 0.644 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr13_-_71963713 0.640 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr12_+_73901370 0.637 ENSMUST00000110461.1
Hif1a
hypoxia inducible factor 1, alpha subunit
chr18_+_12972225 0.622 ENSMUST00000025290.5
Impact
imprinted and ancient
chr4_-_138913915 0.615 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr1_+_179961110 0.614 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr5_+_149439706 0.578 ENSMUST00000031667.4
Tex26
testis expressed 26
chr13_-_64274962 0.558 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr9_-_119322421 0.555 ENSMUST00000040853.4
Oxsr1
oxidative-stress responsive 1
chr1_-_9748376 0.536 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr10_+_93897156 0.510 ENSMUST00000180815.1
4930471D02Rik
RIKEN cDNA 4930471D02 gene
chr5_+_138187485 0.488 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr1_-_16093286 0.472 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr3_+_65528404 0.461 ENSMUST00000047906.3
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr6_-_38046994 0.455 ENSMUST00000096040.4
Svopl
SV2 related protein homolog (rat)-like
chr7_+_19345135 0.422 ENSMUST00000160369.1
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
chr3_+_65528457 0.417 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr17_-_34627365 0.416 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
Ppt2




palmitoyl-protein thioesterase 2




chr13_-_38037069 0.415 ENSMUST00000089840.4
Cage1
cancer antigen 1
chr11_+_119913423 0.414 ENSMUST00000132197.1
Chmp6
charged multivesicular body protein 6
chr5_-_123141067 0.410 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr2_-_73453918 0.406 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr17_-_65884902 0.388 ENSMUST00000024905.9
Ralbp1
ralA binding protein 1
chr8_+_8689666 0.371 ENSMUST00000179702.1
B930078G14Rik
RIKEN cDNA B930078G14 gene
chrM_+_9452 0.370 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr2_+_140152043 0.356 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chr5_+_105876532 0.322 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr10_-_93891141 0.287 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chrX_+_6415736 0.252 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr13_-_64274879 0.234 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr7_+_44836286 0.234 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr18_-_73754457 0.229 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr3_-_57651667 0.221 ENSMUST00000160959.1
Commd2
COMM domain containing 2
chr1_-_39577340 0.213 ENSMUST00000062525.5
Rnf149
ring finger protein 149
chr15_-_73184840 0.204 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chr7_-_43533171 0.203 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33

CD33 antigen

chr17_-_34628005 0.187 ENSMUST00000166040.2
Ppt2
palmitoyl-protein thioesterase 2
chr2_+_165655237 0.185 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr11_+_119913802 0.177 ENSMUST00000026434.6
ENSMUST00000124199.1
Chmp6

charged multivesicular body protein 6

chr4_+_3940747 0.166 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr1_+_86064619 0.158 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr14_+_51884982 0.149 ENSMUST00000167984.1
Mettl17
methyltransferase like 17
chr9_-_21127346 0.145 ENSMUST00000001036.10
Tyk2
tyrosine kinase 2
chr17_+_28691419 0.128 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr5_-_3596071 0.124 ENSMUST00000121877.1
Rbm48
RNA binding motif protein 48
chr16_+_14580221 0.123 ENSMUST00000147024.1
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr13_+_104178797 0.095 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr17_+_29614800 0.088 ENSMUST00000162588.1
Rnf8
ring finger protein 8
chr14_-_104522615 0.081 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr19_+_6047081 0.077 ENSMUST00000025723.8
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr16_+_14705832 0.074 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr3_-_104864420 0.071 ENSMUST00000094028.5
Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr19_+_44562841 0.070 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr13_-_18382041 0.065 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr6_+_14901440 0.048 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr4_+_126024506 0.048 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.6 7.9 GO:1904959 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
1.4 5.5 GO:0090235 regulation of metaphase plate congression(GO:0090235)
1.2 5.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.2 3.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.1 5.7 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
1.0 3.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.8 3.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.8 12.4 GO:0070986 left/right axis specification(GO:0070986)
0.7 3.3 GO:0035063 nuclear speck organization(GO:0035063)
0.6 4.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.6 2.6 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.6 1.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.5 2.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.4 1.8 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 1.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 2.1 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 2.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 3.3 GO:0030035 microspike assembly(GO:0030035)
0.4 2.6 GO:0030242 pexophagy(GO:0030242)
0.3 1.0 GO:0007525 somatic muscle development(GO:0007525)
0.3 3.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 2.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3 1.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 0.8 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.3 7.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 1.3 GO:0060242 contact inhibition(GO:0060242)
0.3 3.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 1.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 3.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 4.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2 4.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.2 2.1 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.2 0.6 GO:0051541 elastin metabolic process(GO:0051541)
0.2 0.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.7 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 1.7 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.2 2.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.1 1.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 2.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 3.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.8 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.1 3.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.0 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 7.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 4.9 GO:0007601 visual perception(GO:0007601)
0.1 3.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 3.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 2.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.6 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 1.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.9 GO:0008209 androgen metabolic process(GO:0008209)
0.0 1.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 2.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 5.7 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0072337 modified amino acid transport(GO:0072337)
0.0 3.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 1.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 3.1 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.4 1.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 5.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.4 4.9 GO:0005922 connexon complex(GO:0005922)
0.3 2.4 GO:0001940 male pronucleus(GO:0001940)
0.3 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.3 5.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 8.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 3.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 5.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 7.2 GO:0043194 axon initial segment(GO:0043194)
0.2 12.4 GO:0005882 intermediate filament(GO:0005882)
0.2 16.4 GO:0072562 blood microparticle(GO:0072562)
0.2 2.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.9 GO:0044305 calyx of Held(GO:0044305)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.0 GO:0061574 ASAP complex(GO:0061574)
0.1 2.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.2 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.3 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.0 GO:0070938 contractile ring(GO:0070938)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 4.2 GO:0000922 spindle pole(GO:0000922)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 5.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.6 GO:0005902 microvillus(GO:0005902)
0.0 3.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.0 GO:0030175 filopodium(GO:0030175)
0.0 1.0 GO:1990391 DNA repair complex(GO:1990391)
0.0 2.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 5.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.3 GO:0030141 secretory granule(GO:0030141)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
1.0 7.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.9 4.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.8 3.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 5.9 GO:0005523 tropomyosin binding(GO:0005523)
0.6 5.7 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.5 3.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.5 10.0 GO:0001848 complement binding(GO:0001848)
0.5 3.0 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.5 2.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 2.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 0.9 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.3 2.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 6.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 4.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 4.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 3.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 4.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 2.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 3.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.0 GO:0017166 vinculin binding(GO:0017166)
0.1 1.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.3 GO:0017022 myosin binding(GO:0017022)
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 1.9 GO:0019894 kinesin binding(GO:0019894)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 10.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 3.0 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 10.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 2.5 PID_ATM_PATHWAY ATM pathway
0.1 2.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 2.1 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 2.1 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.6 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.8 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.0 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.4 4.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.3 5.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 2.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 2.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 5.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 7.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.7 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.0 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.8 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.7 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 3.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 3.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 2.2 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.7 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 1.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling