Motif ID: Nkx2-9

Z-value: 0.367


Transcription factors associated with Nkx2-9:

Gene SymbolEntrez IDGene Name
Nkx2-9 ENSMUSG00000058669.7 Nkx2-9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-9mm10_v2_chr12_-_56613270_56613291-0.124.7e-01Click!


Activity profile for motif Nkx2-9.

activity profile for motif Nkx2-9


Sorted Z-values histogram for motif Nkx2-9

Sorted Z-values for motif Nkx2-9



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_117849223 1.670 ENSMUST00000081387.4
 Birc5
baculoviral IAP repeat-containing 5
chr11_+_117849286 1.068 ENSMUST00000093906.4
 Birc5
baculoviral IAP repeat-containing 5
chr10_+_88091070 1.056 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr14_+_75455957 1.047 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr2_+_173022360 0.988 ENSMUST00000173997.1
 Rbm38
RNA binding motif protein 38
chr4_+_8690399 0.841 ENSMUST00000127476.1
 Chd7
chromodomain helicase DNA binding protein 7
chr5_+_30105161 0.822 ENSMUST00000058045.4
 Gareml
GRB2 associated, regulator of MAPK1-like
chr8_+_95633500 0.816 ENSMUST00000034094.9
 Gins3
GINS complex subunit 3 (Psf3 homolog)
chr11_-_84068766 0.807 ENSMUST00000018792.5
 Dusp14
dual specificity phosphatase 14
chr2_+_181767040 0.800 ENSMUST00000108756.1
 Myt1
myelin transcription factor 1
chr16_-_33380717 0.735 ENSMUST00000180923.1
 1700007L15Rik
RIKEN cDNA 1700007L15 gene
chr13_-_71963713 0.633 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chrX_-_165004829 0.607 ENSMUST00000114890.2
 Gm17604
predicted gene, 17604
chr18_+_77185815 0.556 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr4_-_72852622 0.555 ENSMUST00000179234.1
ENSMUST00000078617.4
 Aldoart1

aldolase 1 A, retrogene 1

chr7_-_101921186 0.533 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr11_+_88718442 0.515 ENSMUST00000138007.1
 C030037D09Rik
RIKEN cDNA C030037D09 gene
chr16_-_59555752 0.505 ENSMUST00000179383.1
ENSMUST00000044604.8
 Crybg3

beta-gamma crystallin domain containing 3

chr2_-_129699833 0.492 ENSMUST00000028883.5
 Pdyn
prodynorphin
chr1_-_181842334 0.478 ENSMUST00000005003.6
 Lbr
lamin B receptor
chr1_-_131097535 0.452 ENSMUST00000016672.4
 Mapkapk2
MAP kinase-activated protein kinase 2
chr11_-_100759740 0.449 ENSMUST00000107361.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr2_+_20737306 0.436 ENSMUST00000114606.1
ENSMUST00000114608.1
 Etl4

enhancer trap locus 4

chr6_-_6217023 0.429 ENSMUST00000015256.8
 Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr4_+_44981389 0.411 ENSMUST00000045078.6
ENSMUST00000128973.1
ENSMUST00000151148.1
 Grhpr


glyoxylate reductase/hydroxypyruvate reductase


chr8_-_70700070 0.404 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr4_-_21685782 0.404 ENSMUST00000076206.4
 Prdm13
PR domain containing 13
chr3_-_37125943 0.396 ENSMUST00000029275.5
 Il2
interleukin 2
chr7_-_101921175 0.395 ENSMUST00000098236.2
 Lrrc51
leucine rich repeat containing 51
chrX_-_95658392 0.389 ENSMUST00000120620.1
 Zc4h2
zinc finger, C4H2 domain containing
chr7_+_4925802 0.387 ENSMUST00000057612.7
 Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr10_+_94198955 0.386 ENSMUST00000020209.9
ENSMUST00000179990.1
 Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr6_-_142507805 0.378 ENSMUST00000134191.1
ENSMUST00000032373.5
 Ldhb

lactate dehydrogenase B

chrX_-_95658379 0.375 ENSMUST00000119640.1
 Zc4h2
zinc finger, C4H2 domain containing
chr17_+_46496753 0.375 ENSMUST00000046497.6
 Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chrX_-_95658416 0.315 ENSMUST00000044382.6
 Zc4h2
zinc finger, C4H2 domain containing
chr2_+_103969528 0.311 ENSMUST00000123437.1
ENSMUST00000163256.1
 Lmo2

LIM domain only 2

chrX_-_102189371 0.305 ENSMUST00000033683.7
 Rps4x
ribosomal protein S4, X-linked
chr19_+_43752996 0.301 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
 Cutc


cutC copper transporter homolog (E.coli)


chr16_-_76403673 0.301 ENSMUST00000052867.7
 Gm9843
predicted gene 9843
chr9_+_75775355 0.287 ENSMUST00000012281.7
 Bmp5
bone morphogenetic protein 5
chr16_+_70313949 0.268 ENSMUST00000163832.1
 Gbe1
glucan (1,4-alpha-), branching enzyme 1
chrX_+_135993820 0.254 ENSMUST00000058119.7
 Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr17_+_34644764 0.250 ENSMUST00000036720.8
 Fkbpl
FK506 binding protein-like
chr7_+_30280094 0.247 ENSMUST00000108187.1
ENSMUST00000014072.5
 Thap8

THAP domain containing 8

chr9_-_60522017 0.242 ENSMUST00000140824.1
 Thsd4
thrombospondin, type I, domain containing 4
chr2_-_152398046 0.231 ENSMUST00000063332.8
ENSMUST00000182625.1
 Sox12

SRY-box containing gene 12

chr3_-_95411176 0.228 ENSMUST00000177599.1
 Gm5070
predicted gene 5070
chr10_+_63061582 0.227 ENSMUST00000020266.8
ENSMUST00000178684.1
 Pbld1

phenazine biosynthesis-like protein domain containing 1

chr9_-_106887000 0.223 ENSMUST00000055843.7
 Rbm15b
RNA binding motif protein 15B
chr7_-_142576492 0.211 ENSMUST00000140716.1
 H19
H19 fetal liver mRNA
chr11_+_72607221 0.211 ENSMUST00000021148.6
ENSMUST00000138247.1
 Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr8_-_79399513 0.195 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
 Smad1


SMAD family member 1


chr7_+_75610038 0.195 ENSMUST00000125771.1
 Akap13
A kinase (PRKA) anchor protein 13
chr16_-_46155077 0.193 ENSMUST00000059524.5
 Gm4737
predicted gene 4737
chr15_+_79690869 0.190 ENSMUST00000046463.8
 Gtpbp1
GTP binding protein 1
chr15_-_98918131 0.186 ENSMUST00000023736.8
 Lmbr1l
limb region 1 like
chr19_-_43752924 0.183 ENSMUST00000045562.5
 Cox15
cytochrome c oxidase assembly protein 15
chr1_-_74600564 0.177 ENSMUST00000127938.1
ENSMUST00000154874.1
 Rnf25

ring finger protein 25

chr1_+_59256906 0.172 ENSMUST00000160662.1
ENSMUST00000114248.2
 Cdk15

cyclin-dependent kinase 15

chr9_+_74861888 0.172 ENSMUST00000056006.9
 Onecut1
one cut domain, family member 1
chr13_+_72632597 0.171 ENSMUST00000172353.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr10_+_14523062 0.169 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr8_-_80880479 0.168 ENSMUST00000034150.8
 Gab1
growth factor receptor bound protein 2-associated protein 1
chr17_-_36058371 0.160 ENSMUST00000113742.2
 Gm11127
predicted gene 11127
chrX_+_7899350 0.160 ENSMUST00000033498.3
 Timm17b
translocase of inner mitochondrial membrane 17b
chrX_-_49788204 0.152 ENSMUST00000114893.1
 Igsf1
immunoglobulin superfamily, member 1
chr7_+_44848991 0.151 ENSMUST00000107885.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr4_-_41275091 0.149 ENSMUST00000030143.6
ENSMUST00000108068.1
 Ubap2

ubiquitin-associated protein 2

chr11_-_22982090 0.141 ENSMUST00000093270.5
ENSMUST00000071068.8
ENSMUST00000159081.1
ENSMUST00000160826.1
 Commd1


RP23-242C19.7
COMM domain containing 1


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (B3gnt2), transcript variant 2, mRNA
chr8_+_95320440 0.140 ENSMUST00000162294.1
 Tepp
testis, prostate and placenta expressed
chr18_-_35662180 0.138 ENSMUST00000025209.4
ENSMUST00000096573.2
 Spata24

spermatogenesis associated 24

chrX_+_42149534 0.138 ENSMUST00000127618.1
 Stag2
stromal antigen 2
chr3_-_34351685 0.137 ENSMUST00000174114.1
 Gm20514
predicted gene 20514
chrX_+_42149288 0.134 ENSMUST00000115073.2
ENSMUST00000115072.1
 Stag2

stromal antigen 2

chr13_+_75839868 0.132 ENSMUST00000022082.7
 Glrx
glutaredoxin
chr4_+_36952930 0.129 ENSMUST00000144029.1
 Gm12371
predicted gene 12371
chr7_-_126475082 0.128 ENSMUST00000032978.6
 Sh2b1
SH2B adaptor protein 1
chr1_-_135688094 0.127 ENSMUST00000112103.1
 Nav1
neuron navigator 1
chr7_-_102018139 0.127 ENSMUST00000094134.3
 Il18bp
interleukin 18 binding protein
chr2_-_165283599 0.122 ENSMUST00000155289.1
 Slc35c2
solute carrier family 35, member C2
chr15_+_58933774 0.115 ENSMUST00000022980.3
 Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr8_+_123212857 0.114 ENSMUST00000060133.6
 Spata33
spermatogenesis associated 33
chr10_+_68723723 0.111 ENSMUST00000080995.6
 Tmem26
transmembrane protein 26
chr11_+_114668524 0.111 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
 Rpl38



ribosomal protein L38



chr4_-_141664063 0.111 ENSMUST00000084203.4
 Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr12_-_56536895 0.110 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr6_+_66896480 0.105 ENSMUST00000114222.1
 Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr5_+_67260696 0.097 ENSMUST00000161233.1
ENSMUST00000160352.1
 Tmem33

transmembrane protein 33

chrX_+_152001845 0.091 ENSMUST00000026289.3
ENSMUST00000112617.3
 Hsd17b10

hydroxysteroid (17-beta) dehydrogenase 10

chr16_+_30065333 0.090 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr14_+_53665912 0.087 ENSMUST00000181768.1
 Trav3-3
T cell receptor alpha variable 3-3
chrX_+_56779437 0.086 ENSMUST00000114773.3
 Fhl1
four and a half LIM domains 1
chr2_+_80638798 0.086 ENSMUST00000028382.6
ENSMUST00000124377.1
 Nup35

nucleoporin 35

chrM_+_7759 0.081 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_-_25575224 0.078 ENSMUST00000039156.6
 Phpt1
phosphohistidine phosphatase 1
chr9_-_56161051 0.077 ENSMUST00000034876.8
 Tspan3
tetraspanin 3
chr10_+_127420867 0.073 ENSMUST00000064793.6
 R3hdm2
R3H domain containing 2
chr5_-_24445254 0.068 ENSMUST00000030800.6
 Fastk
Fas-activated serine/threonine kinase
chr10_+_82378593 0.068 ENSMUST00000165906.1
 Gm4924
predicted gene 4924
chr2_+_140152043 0.065 ENSMUST00000104994.2
 Gm17374
predicted gene, 17374
chr1_+_9545397 0.061 ENSMUST00000072079.7
 Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr6_+_66896397 0.060 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
 Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr16_-_92466081 0.058 ENSMUST00000060005.8
 Rcan1
regulator of calcineurin 1
chr12_-_24493656 0.042 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr16_+_32271468 0.042 ENSMUST00000093183.3
 Smco1
single-pass membrane protein with coiled-coil domains 1
chr1_+_87264345 0.035 ENSMUST00000118687.1
ENSMUST00000027472.6
 Efhd1

EF hand domain containing 1

chr6_+_122707489 0.035 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
 Nanog


Nanog homeobox


chr10_+_19934472 0.035 ENSMUST00000095806.3
ENSMUST00000120259.1
 Map3k5

mitogen-activated protein kinase kinase kinase 5

chr5_+_67260565 0.031 ENSMUST00000037918.5
ENSMUST00000162543.1
 Tmem33

transmembrane protein 33

chr5_+_147430407 0.019 ENSMUST00000176600.1
 Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr17_-_25861456 0.019 ENSMUST00000079461.8
ENSMUST00000176923.1
 Wdr90

WD repeat domain 90

chr9_-_54647199 0.017 ENSMUST00000128163.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_+_57504012 0.017 ENSMUST00000080514.7
 Rpp25
ribonuclease P/MRP 25 subunit
chr3_+_138277489 0.016 ENSMUST00000004232.9
 Adh1
alcohol dehydrogenase 1 (class I)
chr17_-_51833278 0.014 ENSMUST00000133574.1
 Satb1
special AT-rich sequence binding protein 1
chr11_-_109363654 0.013 ENSMUST00000070956.3
 Gm11696
predicted gene 11696
chr15_+_100469034 0.012 ENSMUST00000037001.8
 Letmd1
LETM1 domain containing 1
chr7_-_19665005 0.012 ENSMUST00000055242.9
 Clptm1
cleft lip and palate associated transmembrane protein 1
chr3_-_153912966 0.012 ENSMUST00000089950.4
 Rabggtb
RAB geranylgeranyl transferase, b subunit
chr6_-_101377342 0.011 ENSMUST00000151175.1
 Pdzrn3
PDZ domain containing RING finger 3
chr12_+_71136848 0.009 ENSMUST00000149564.1
ENSMUST00000045907.8
 2700049A03Rik

RIKEN cDNA 2700049A03 gene

chrX_-_7899220 0.001 ENSMUST00000033497.2
 Pqbp1
polyglutamine binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.4 1.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.3 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 0.8 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.8 GO:0060539 diaphragm development(GO:0060539)
0.1 0.3 GO:0021502 neural fold elevation formation(GO:0021502)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0032133 interphase microtubule organizing center(GO:0031021) chromosome passenger complex(GO:0032133)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.3 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 2.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.8 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis