Motif ID: Nkx6-3_Dbx2_Barx2

Z-value: 0.559

Transcription factors associated with Nkx6-3_Dbx2_Barx2:

Gene SymbolEntrez IDGene Name
Barx2 ENSMUSG00000032033.10 Barx2
Dbx2 ENSMUSG00000045608.6 Dbx2
Nkx6-3 ENSMUSG00000063672.6 Nkx6-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbx2mm10_v2_chr15_-_95655960_956559600.382.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-3_Dbx2_Barx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_14621805 6.146 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr4_+_136143497 3.556 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr4_-_14621494 3.264 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621669 3.154 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr13_+_94083490 2.455 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr14_+_80000292 2.165 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr8_-_21906412 2.018 ENSMUST00000051965.4
Defb11
defensin beta 11
chr4_+_102589687 1.869 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr14_+_69347587 1.565 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr11_+_109543694 1.448 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr15_-_8710734 1.402 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_70842617 1.367 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_-_118244861 1.356 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr17_-_81649607 1.302 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr5_+_144100387 1.258 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr15_-_8710409 1.180 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_109917639 1.127 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr2_+_125136692 1.078 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr13_+_83732438 1.014 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr7_+_57387304 1.006 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr15_-_33687840 1.005 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr19_-_57239310 0.980 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr10_-_110000219 0.927 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr7_-_45103747 0.911 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr9_+_53771499 0.857 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr13_-_105054895 0.836 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr16_+_11406618 0.821 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr17_-_45659312 0.764 ENSMUST00000120717.1
Capn11
calpain 11
chrX_+_170009892 0.762 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr13_+_109926832 0.721 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr5_+_29195983 0.658 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr8_+_94172618 0.623 ENSMUST00000034214.6
Mt2
metallothionein 2
chr8_-_70212268 0.622 ENSMUST00000110127.1
Slc25a42
solute carrier family 25, member 42
chr15_+_82252397 0.595 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_-_70212251 0.592 ENSMUST00000063788.7
Slc25a42
solute carrier family 25, member 42
chr2_+_32606946 0.577 ENSMUST00000113290.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr10_+_116143881 0.569 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr18_+_23753708 0.565 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_-_43981757 0.561 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr19_+_5474681 0.557 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr3_-_116712644 0.556 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr6_-_137169710 0.553 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr10_+_116018213 0.548 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chr2_+_36230426 0.545 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_+_32606979 0.542 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr8_+_15011025 0.532 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr6_-_136941887 0.514 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_+_16778101 0.503 ENSMUST00000026432.6
Cdh9
cadherin 9
chr7_+_79273201 0.500 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chrX_+_169685191 0.491 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr13_-_105271039 0.488 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr2_-_113829069 0.467 ENSMUST00000024005.7
Scg5
secretogranin V
chrY_+_90785442 0.453 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr7_-_57387172 0.450 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr19_-_32196393 0.420 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr8_+_121116163 0.395 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr8_-_105568298 0.389 ENSMUST00000005849.5
Agrp
agouti related protein
chr4_-_149126688 0.370 ENSMUST00000030815.2
Cort
cortistatin
chr18_+_24603952 0.356 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr6_-_136941694 0.352 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr4_+_118961578 0.348 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr3_-_116253467 0.347 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr4_-_108301045 0.345 ENSMUST00000043616.6
Zyg11b
zyg-ll family member B, cell cycle regulator
chr6_-_136941494 0.336 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_5895319 0.329 ENSMUST00000026926.4
ENSMUST00000102981.3
Sec61a2

Sec61, alpha subunit 2 (S. cerevisiae)

chr6_+_145934113 0.325 ENSMUST00000032383.7
Sspn
sarcospan
chr7_-_100583072 0.307 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr12_+_102128718 0.306 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_69712461 0.305 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr11_+_78037959 0.300 ENSMUST00000073660.6
Flot2
flotillin 2
chr14_+_4198185 0.299 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr11_+_78037931 0.298 ENSMUST00000072289.5
ENSMUST00000100784.2
Flot2

flotillin 2

chr4_-_40722307 0.290 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr4_-_129378116 0.271 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chrX_-_157415286 0.267 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr1_-_72284248 0.245 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr17_+_26715644 0.236 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr2_-_45112890 0.228 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr18_+_55057557 0.219 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr5_-_34660068 0.219 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr17_-_36032682 0.214 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr18_+_59062462 0.213 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr8_+_40354303 0.212 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr7_-_38019505 0.206 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr4_-_134245579 0.200 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr17_-_50094277 0.189 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr11_-_82908360 0.188 ENSMUST00000103213.3
Nle1
notchless homolog 1 (Drosophila)
chr1_-_168432270 0.188 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr12_-_20900867 0.188 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr1_+_133309778 0.184 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr18_+_59062282 0.184 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr8_-_106573461 0.177 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_-_84715160 0.177 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr8_+_107031218 0.173 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr9_+_113812547 0.163 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr9_-_15301555 0.157 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr2_+_151494182 0.150 ENSMUST00000089140.6
Nsfl1c
NSFL1 (p97) cofactor (p47)
chr10_-_63927434 0.149 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr18_-_24603464 0.136 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr18_+_57468478 0.136 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr4_+_13743424 0.133 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_-_80405425 0.131 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr4_-_147809788 0.128 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr2_+_55437100 0.126 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr11_+_97840780 0.119 ENSMUST00000054783.4
B230217C12Rik
RIKEN cDNA B230217C12 gene
chr6_+_113442569 0.119 ENSMUST00000101070.4
Jagn1
jagunal homolog 1 (Drosophila)
chr8_+_34054622 0.117 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr18_-_43477764 0.115 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr13_-_21468474 0.114 ENSMUST00000068235.4
Nkapl
NFKB activating protein-like
chr12_+_10390756 0.101 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr18_-_24603791 0.098 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr13_-_102906046 0.096 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr11_+_116843278 0.093 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr3_+_94837533 0.093 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr10_-_86011833 0.089 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr5_+_24393640 0.086 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr12_+_72536342 0.076 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr8_+_72219726 0.074 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr11_-_4095344 0.072 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr1_+_72284367 0.061 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_-_33718789 0.061 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr2_-_84650676 0.058 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr3_-_62506970 0.057 ENSMUST00000029336.4
Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr1_-_127840290 0.056 ENSMUST00000061512.2
Map3k19
mitogen-activated protein kinase kinase kinase 19
chr4_+_145585166 0.047 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr7_+_19119853 0.044 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr8_-_66486494 0.043 ENSMUST00000026681.5
Tma16
translation machinery associated 16 homolog (S. cerevisiae)
chr2_-_177267036 0.043 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr2_-_84650490 0.041 ENSMUST00000066177.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr4_+_147492417 0.040 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr7_-_133702515 0.037 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr3_+_94837702 0.030 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr7_+_103550368 0.028 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr13_-_102905740 0.023 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr7_-_46672537 0.022 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr15_-_75905349 0.020 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr10_+_23894688 0.017 ENSMUST00000041416.7
Vnn1
vanin 1
chr2_-_80128834 0.017 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr11_+_51261719 0.014 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr18_+_37655891 0.012 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr18_+_3382979 0.010 ENSMUST00000025073.5
Cul2
cullin 2
chr11_+_102285161 0.010 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chrX_-_143933089 0.009 ENSMUST00000087313.3
Dcx
doublecortin
chr5_+_96210115 0.007 ENSMUST00000036437.6
ENSMUST00000121477.1
Mrpl1

mitochondrial ribosomal protein L1

chr1_-_34439672 0.003 ENSMUST00000042493.8
Ccdc115
coiled-coil domain containing 115
chr4_+_145510759 0.003 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.6 GO:0019532 oxalate transport(GO:0019532)
0.6 2.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 1.2 GO:0015866 ADP transport(GO:0015866)
0.4 1.1 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 1.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.3 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2 1.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.6 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 2.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.4 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 3.6 GO:0030903 notochord development(GO:0030903)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 1.3 GO:0033572 transferrin transport(GO:0033572)
0.1 0.6 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.2 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 2.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.0 0.5 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 1.7 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 2.2 GO:0042581 specific granule(GO:0042581)
0.1 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 13.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0030689 Noc complex(GO:0030689)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.4 2.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.3 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 1.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 16.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis