Motif ID: Nr0b1

Z-value: 0.856


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_861917820.086.4e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_45844228 4.768 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 4.706 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr9_+_80165079 3.858 ENSMUST00000184480.1
Myo6
myosin VI
chr11_+_102604370 3.729 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr9_+_80165013 3.466 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr7_+_79500081 3.443 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr7_+_79500018 3.398 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr5_+_64803513 3.162 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr1_-_9700209 2.839 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr18_+_35829798 2.558 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr17_-_70851189 2.339 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr10_-_81350389 2.200 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr4_-_132422484 2.132 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chrX_-_145505175 2.128 ENSMUST00000143610.1
Amot
angiomotin
chr13_-_29984219 2.042 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr1_+_42697146 2.006 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr4_+_116221633 1.989 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr4_-_132422394 1.984 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr14_+_11553523 1.938 ENSMUST00000022264.6
Ptprg
protein tyrosine phosphatase, receptor type, G
chr7_+_19094594 1.833 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr4_+_116221689 1.819 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr7_+_28180226 1.695 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_94328242 1.681 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr19_-_46039442 1.588 ENSMUST00000137771.1
Ldb1
LIM domain binding 1
chr11_+_94327984 1.532 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr7_+_28180272 1.445 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr4_+_116221590 1.407 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_+_77930800 1.389 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr2_-_54085542 1.340 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_123750236 1.284 ENSMUST00000102636.3
Akirin1
akirin 1
chr3_+_86224665 1.188 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr6_+_47454320 1.163 ENSMUST00000031697.8
Cul1
cullin 1
chr5_+_30913398 1.145 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr7_+_82867327 1.100 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr3_-_123690806 1.100 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_-_115436508 1.072 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr4_+_148130883 1.067 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr5_-_99037035 0.959 ENSMUST00000031277.6
Prkg2
protein kinase, cGMP-dependent, type II
chr7_-_65371210 0.881 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr5_-_99037342 0.876 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr15_-_38078842 0.843 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr13_-_94358818 0.791 ENSMUST00000059598.2
Gm9776
predicted gene 9776
chr14_+_75845296 0.759 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chr11_-_70687917 0.689 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr18_+_80046854 0.676 ENSMUST00000070219.7
Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr5_+_110230975 0.653 ENSMUST00000031474.7
ENSMUST00000086674.5
Ankle2

ankyrin repeat and LEM domain containing 2

chr4_-_138913915 0.636 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr2_+_71786923 0.610 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr16_+_44173239 0.609 ENSMUST00000119746.1
Gm608
predicted gene 608
chr13_+_94358943 0.579 ENSMUST00000022196.3
Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr17_-_80728026 0.547 ENSMUST00000112389.2
ENSMUST00000025089.7
Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr17_+_29490812 0.547 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr1_+_59764264 0.540 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr2_+_4718145 0.533 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr17_-_23745829 0.529 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2
chr1_+_140246216 0.522 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr11_-_74723829 0.503 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr13_-_64274879 0.446 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr11_+_105181793 0.435 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
Tlk2


tousled-like kinase 2 (Arabidopsis)


chr19_+_45015198 0.430 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr12_+_49385174 0.339 ENSMUST00000110746.1
3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr11_+_107547925 0.337 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr4_-_135971894 0.312 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr5_+_121711609 0.309 ENSMUST00000051950.7
Atxn2
ataxin 2
chr17_+_34898463 0.298 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr4_-_148130678 0.292 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr8_-_95434869 0.252 ENSMUST00000034249.6
Gtl3
gene trap locus 3
chr11_+_50237002 0.250 ENSMUST00000180443.1
Gm26542
predicted gene, 26542
chr11_+_23306884 0.239 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr15_+_80711292 0.228 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr15_+_35371498 0.186 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr5_+_31193227 0.178 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
Snx17


sorting nexin 17


chr11_+_105181527 0.165 ENSMUST00000106941.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr11_+_23306910 0.145 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr8_-_105707933 0.122 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr13_-_55488038 0.107 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
Dbn1


drebrin 1


chr4_-_129696817 0.106 ENSMUST00000102588.3
Tmem39b
transmembrane protein 39b
chr3_-_86920830 0.092 ENSMUST00000029719.8
Dclk2
doublecortin-like kinase 2
chr2_+_129198757 0.088 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr19_-_6077183 0.079 ENSMUST00000025711.5
ENSMUST00000160590.1
Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr2_+_30066419 0.052 ENSMUST00000067996.6
Set
SET nuclear oncogene
chr8_-_85080652 0.020 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr8_-_85080679 0.016 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr9_-_45984816 0.004 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.0 4.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.7 3.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
0.6 7.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.5 2.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 2.0 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.4 1.6 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 2.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 0.8 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.8 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.2 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.6 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 0.8 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 1.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.5 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.2 0.5 GO:0043622 cortical microtubule organization(GO:0043622)
0.1 0.3 GO:0036166 phenotypic switching(GO:0036166)
0.1 2.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.8 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 5.2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.6 GO:0035878 nail development(GO:0035878)
0.1 3.1 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 1.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 1.8 GO:1901998 toxin transport(GO:1901998)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.5 GO:0045180 basal cortex(GO:0045180)
0.5 2.2 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 1.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 7.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 5.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0000235 astral microtubule(GO:0000235)
0.1 1.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.8 GO:0045298 tubulin complex(GO:0045298)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 3.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 2.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.1 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 5.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 1.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 2.1 GO:0043532 angiostatin binding(GO:0043532)
0.4 2.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 1.1 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.2 1.6 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.9 GO:0071253 connexin binding(GO:0071253)
0.1 2.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 2.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 7.3 GO:0003774 motor activity(GO:0003774)
0.1 3.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.8 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 5.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 6.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 2.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.9 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_TNF_PATHWAY TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.4 7.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 2.0 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.8 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 2.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 3.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production