Motif ID: Nr1h4

Z-value: 0.662


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_94179089 2.755 ENSMUST00000034215.6
Mt1
metallothionein 1
chr9_+_50752758 2.751 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr7_-_99695809 2.153 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr7_+_19176416 2.058 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr4_+_117849361 2.051 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr10_+_13966268 2.010 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr4_+_117849193 2.000 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr19_+_6400523 1.972 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr4_+_42916647 1.964 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr5_-_147725988 1.926 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr10_-_33995054 1.813 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr4_+_53440388 1.792 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr19_+_5474681 1.792 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr15_+_80287234 1.771 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr4_+_42917234 1.753 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chrX_+_73064787 1.723 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr6_-_124769548 1.637 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr1_+_75507077 1.621 ENSMUST00000037330.4
Inha
inhibin alpha
chr7_-_105482197 1.611 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr7_-_44670820 1.528 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr14_-_26170283 1.349 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr2_-_152951547 1.257 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chr5_-_116422858 1.197 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr6_-_59426279 1.156 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr11_-_74590065 1.097 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr19_+_44992127 1.065 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_-_152951688 1.052 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr19_+_6400611 1.039 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr7_-_31055594 1.016 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr4_-_123116686 0.947 ENSMUST00000166337.1
Gm17244
predicted gene, 17244
chr9_-_20879718 0.927 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr9_-_42399709 0.913 ENSMUST00000160940.1
Tecta
tectorin alpha
chr4_-_15149755 0.893 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr11_+_97685794 0.881 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chrX_+_77511002 0.863 ENSMUST00000088217.5
Tbl1x
transducin (beta)-like 1 X-linked
chr11_-_74590186 0.853 ENSMUST00000102521.1
Rap1gap2
RAP1 GTPase activating protein 2
chr4_-_141664063 0.852 ENSMUST00000084203.4
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr2_+_32621750 0.831 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr11_+_75513540 0.820 ENSMUST00000042808.6
ENSMUST00000118243.1
Scarf1

scavenger receptor class F, member 1

chr1_+_172341197 0.773 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr7_+_16310412 0.763 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr9_-_32541589 0.754 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr10_-_89732253 0.718 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr7_-_127936097 0.717 ENSMUST00000150591.1
Prss36
protease, serine, 36
chr17_-_57087729 0.710 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr11_+_75655873 0.682 ENSMUST00000108431.2
Myo1c
myosin IC
chr10_-_78298162 0.665 ENSMUST00000105389.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr8_+_25720054 0.650 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr1_+_36511867 0.639 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr7_-_47133684 0.590 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_+_78037959 0.588 ENSMUST00000073660.6
Flot2
flotillin 2
chr9_+_44107268 0.565 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr6_+_4902913 0.563 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr4_-_108406676 0.554 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr2_-_130638094 0.551 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr4_+_133039482 0.545 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr5_-_36582381 0.532 ENSMUST00000141043.1
ENSMUST00000031094.8
Tbc1d14

TBC1 domain family, member 14

chr9_+_54538984 0.530 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr18_-_67449083 0.519 ENSMUST00000025408.8
Afg3l2
AFG3(ATPase family gene 3)-like 2 (yeast)
chr15_+_86214431 0.509 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a
chr4_-_42528175 0.500 ENSMUST00000180201.1
Gm13298
predicted gene 13298
chr9_+_44107286 0.498 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr14_-_70766598 0.497 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7

chr2_-_51934644 0.459 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr15_-_98567630 0.439 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr1_+_152954966 0.435 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr6_-_86793522 0.434 ENSMUST00000001187.8
Anxa4
annexin A4
chr6_+_4903298 0.429 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_+_97685903 0.424 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr10_+_116301374 0.415 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr4_-_124850652 0.415 ENSMUST00000125776.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr1_+_63176818 0.409 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr7_+_44442398 0.396 ENSMUST00000058667.8
Lrrc4b
leucine rich repeat containing 4B
chr2_+_176802233 0.389 ENSMUST00000132883.1
Gm14295
predicted gene 14295
chr9_-_63377835 0.381 ENSMUST00000034920.9
Map2k5
mitogen-activated protein kinase kinase 5
chr2_-_176149825 0.378 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr9_+_22003035 0.363 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr5_+_123076275 0.348 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr10_-_67548944 0.343 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr3_-_96293953 0.319 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr3_+_96181151 0.318 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr2_+_177004553 0.318 ENSMUST00000126358.1
Gm14419
predicted gene 14419
chr4_-_123904826 0.311 ENSMUST00000181292.1
Gm26606
predicted gene, 26606
chr8_+_3631109 0.306 ENSMUST00000004745.8
Stxbp2
syntaxin binding protein 2
chr13_-_38960498 0.305 ENSMUST00000167513.1
Slc35b3
solute carrier family 35, member B3
chr13_+_40859768 0.299 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_-_106656081 0.288 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr2_+_176711933 0.287 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chrM_+_8600 0.278 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrX_-_18461371 0.276 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr2_-_177202829 0.275 ENSMUST00000133301.1
Gm14410
predicted gene 14410
chr7_+_138846579 0.274 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr2_+_91650116 0.270 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr8_-_71043040 0.270 ENSMUST00000170101.1
Gm17576
predicted gene, 17576
chr8_-_70510552 0.258 ENSMUST00000125184.1
Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr2_-_175203061 0.251 ENSMUST00000165892.1
Gm14391
predicted gene 14391
chr8_-_70510322 0.238 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chr1_+_93215899 0.236 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr2_-_120353094 0.233 ENSMUST00000028752.7
ENSMUST00000102501.3
Vps39

vacuolar protein sorting 39 (yeast)

chrX_-_102644210 0.230 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr12_-_98577940 0.225 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr11_+_116198853 0.225 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr9_-_59353430 0.225 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr16_+_20535475 0.215 ENSMUST00000090023.6
ENSMUST00000007216.8
Ap2m1

adaptor-related protein complex 2, mu 1 subunit

chr7_-_105787544 0.211 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr14_+_34220028 0.203 ENSMUST00000119693.1
ENSMUST00000035351.5
Syt15

synaptotagmin XV

chr1_-_162859684 0.197 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr6_-_30390997 0.196 ENSMUST00000152391.2
ENSMUST00000115184.1
ENSMUST00000080812.7
ENSMUST00000102992.3
Zc3hc1



zinc finger, C3HC type 1



chr4_+_147507600 0.192 ENSMUST00000063704.7
Gm13152
predicted gene 13152
chr5_-_140649018 0.185 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)
chr4_-_42581621 0.184 ENSMUST00000178742.1
Gm10592
predicted gene 10592
chrX_+_101532734 0.180 ENSMUST00000118878.1
ENSMUST00000101341.2
ENSMUST00000149274.1
Taf1


TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor


chr10_+_89686365 0.179 ENSMUST00000181598.1
1500026H17Rik
RIKEN cDNA 1500026H17 gene
chr2_+_177762898 0.164 ENSMUST00000119838.2
Gm14322
predicted gene 14322
chr5_-_24445254 0.162 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr2_+_181497165 0.151 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr7_-_105787567 0.149 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr4_-_42084291 0.132 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr16_+_94370618 0.129 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr10_+_23894688 0.124 ENSMUST00000041416.7
Vnn1
vanin 1
chr17_-_35910032 0.121 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr4_+_146654927 0.109 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr13_+_74350313 0.106 ENSMUST00000160021.1
ENSMUST00000162672.1
ENSMUST00000162376.1
Ccdc127


coiled-coil domain containing 127


chr9_+_44107226 0.103 ENSMUST00000114816.1
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr9_+_108662098 0.084 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr2_+_181497223 0.082 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr3_+_137623672 0.075 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr17_-_35909626 0.070 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr17_+_24470393 0.064 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr11_+_5955693 0.060 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr17_+_25133385 0.047 ENSMUST00000040729.2
Clcn7
chloride channel 7
chr14_-_31206666 0.044 ENSMUST00000165981.1
ENSMUST00000171735.1
Nisch

nischarin

chr17_-_21933022 0.044 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chr16_-_94370647 0.037 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_+_4594312 0.031 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr9_+_56994932 0.016 ENSMUST00000034832.6
Ptpn9
protein tyrosine phosphatase, non-receptor type 9
chr4_-_137782182 0.013 ENSMUST00000153588.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr5_-_124531308 0.012 ENSMUST00000062153.7
Rilpl1
Rab interacting lysosomal protein-like 1
chr2_+_176230177 0.012 ENSMUST00000135430.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr16_-_4523056 0.010 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr4_-_133672601 0.009 ENSMUST00000062118.4
ENSMUST00000067902.6
Pigv

phosphatidylinositol glycan anchor biosynthesis, class V

chr8_+_104831572 0.001 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 2.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 2.8 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.4 1.8 GO:0015871 choline transport(GO:0015871)
0.3 1.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 1.9 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 2.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.6 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.2 0.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.6 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 2.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 0.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 1.0 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 0.8 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.6 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.5 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 1.8 GO:0030431 sleep(GO:0030431)
0.1 0.8 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.2 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 2.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 1.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0019401 alditol biosynthetic process(GO:0019401)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.2 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.0 2.3 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 2.0 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.5 2.8 GO:0097512 cardiac myofibril(GO:0097512)
0.3 1.5 GO:0097513 myosin II filament(GO:0097513)
0.2 0.7 GO:0045160 myosin I complex(GO:0045160)
0.2 1.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 2.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123) HOPS complex(GO:0030897)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 3.9 GO:0098793 presynapse(GO:0098793)
0.0 0.5 GO:0012505 endomembrane system(GO:0012505)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 1.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 4.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 2.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.1 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 3.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 2.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.4 4.0 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 2.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 1.8 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 1.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 5.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.5 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation