Motif ID: Nr2c1

Z-value: 0.725


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_94148023-0.421.0e-02Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_29411736 4.514 ENSMUST00000115236.1
Ntm
neurotrimin
chr9_-_29412204 4.136 ENSMUST00000115237.1
Ntm
neurotrimin
chr15_+_80091320 3.997 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr15_+_3270767 3.730 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr9_-_21037775 3.682 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr6_+_22875496 3.575 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr10_+_58813359 3.472 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr4_-_46991842 3.317 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_+_68572245 3.099 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr11_-_76577701 3.005 ENSMUST00000176179.1
Abr
active BCR-related gene
chr7_+_45896941 2.509 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr10_-_86498836 2.445 ENSMUST00000120638.1
Syn3
synapsin III
chr12_+_61523889 2.432 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr11_+_75193783 2.378 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr7_+_45897429 1.708 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr12_-_83487708 1.625 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr1_+_195017399 1.619 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr11_-_26210553 1.535 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr15_-_79505241 1.511 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr10_-_86498872 1.355 ENSMUST00000121789.1
Syn3
synapsin III
chr1_+_133309778 1.270 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr2_+_92375306 1.220 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chr13_+_31558157 1.208 ENSMUST00000042118.8
Foxq1
forkhead box Q1
chr4_-_129440800 1.170 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr1_-_155417283 1.160 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_-_29253001 1.112 ENSMUST00000071201.4
Ntng2
netrin G2
chr2_+_130406478 1.083 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr14_+_75136326 1.081 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr11_-_3504766 1.053 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr1_+_58973521 1.025 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr19_-_45998479 1.023 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr6_-_83054415 1.019 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr7_+_30232032 0.968 ENSMUST00000149654.1
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr17_-_46032366 0.967 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chrX_-_59567348 0.965 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr16_-_4523056 0.954 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr11_-_62281342 0.942 ENSMUST00000072916.4
Zswim7
zinc finger SWIM-type containing 7
chr6_-_142964404 0.933 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr4_+_127172866 0.899 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr16_-_44139630 0.898 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr17_-_35910032 0.895 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr15_-_79141197 0.876 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr12_+_4082574 0.866 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_+_110768169 0.857 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr1_+_58586381 0.843 ENSMUST00000027193.8
Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chr8_+_119394866 0.835 ENSMUST00000098367.4
Mlycd
malonyl-CoA decarboxylase
chr4_-_130174691 0.823 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr17_-_35909626 0.820 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr5_+_117120120 0.814 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr6_+_125145235 0.753 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chrX_+_10485121 0.743 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr15_-_98093245 0.722 ENSMUST00000180657.1
Senp1
SUMO1/sentrin specific peptidase 1
chr14_+_54360826 0.673 ENSMUST00000000985.5
Oxa1l
oxidase assembly 1-like
chr7_-_45921418 0.661 ENSMUST00000038876.5
Emp3
epithelial membrane protein 3
chr10_-_67548944 0.658 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr7_+_46397648 0.658 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr12_+_83987854 0.652 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr6_+_124663027 0.609 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr6_+_83054653 0.573 ENSMUST00000092618.6
Aup1
ancient ubiquitous protein 1
chr7_+_30232310 0.566 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr4_+_133039482 0.561 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr11_+_4986824 0.544 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr7_-_45920830 0.543 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr5_-_137741601 0.537 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr16_-_44139196 0.531 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr19_-_3912711 0.488 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr14_+_57798156 0.472 ENSMUST00000128764.1
Sap18
Sin3-associated polypeptide 18
chr17_-_35235755 0.469 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr13_-_9878998 0.465 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr17_-_12992188 0.436 ENSMUST00000159986.1
Wtap
Wilms' tumour 1-associating protein
chr2_+_29869484 0.429 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr1_+_12718496 0.428 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr3_+_96830069 0.426 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr11_+_62281457 0.409 ENSMUST00000101075.4
ENSMUST00000050646.6
Ttc19

tetratricopeptide repeat domain 19

chr1_+_74284930 0.400 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr15_+_89429560 0.386 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr7_+_30712209 0.377 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr4_-_11076160 0.365 ENSMUST00000058183.8
Ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr19_+_4962306 0.363 ENSMUST00000025836.4
Mrpl11
mitochondrial ribosomal protein L11
chr1_-_58586191 0.356 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr2_+_153345809 0.332 ENSMUST00000109790.1
Asxl1
additional sex combs like 1
chr7_-_79842287 0.324 ENSMUST00000049004.6
Anpep
alanyl (membrane) aminopeptidase
chr5_-_137072254 0.317 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr11_-_50325599 0.307 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr13_-_73328442 0.303 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr4_+_156215920 0.285 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr3_-_115888086 0.282 ENSMUST00000067500.5
A930005H10Rik
RIKEN cDNA A930005H10 gene
chr4_+_117252010 0.279 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr10_+_93589413 0.268 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr15_+_81811414 0.266 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr11_-_107337556 0.247 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_107631322 0.230 ENSMUST00000106703.1
Gm10961
predicted gene 10961
chr10_+_59395632 0.211 ENSMUST00000092511.4
Gm10273
predicted pseudogene 10273
chr1_-_74284636 0.199 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr11_+_3488275 0.181 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr11_-_97766508 0.178 ENSMUST00000107579.1
ENSMUST00000018685.2
Cwc25

CWC25 spliceosome-associated protein homolog (S. cerevisiae)

chr3_+_58525821 0.167 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr11_+_116853752 0.166 ENSMUST00000021173.7
Mfsd11
major facilitator superfamily domain containing 11
chr2_+_106695594 0.157 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chrX_+_100729917 0.156 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr14_+_57798637 0.150 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr2_-_164804876 0.137 ENSMUST00000103094.4
ENSMUST00000017451.6
Acot8

acyl-CoA thioesterase 8

chr1_-_167285110 0.135 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr15_+_86214431 0.132 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a
chr8_+_95825353 0.132 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr15_-_89429093 0.116 ENSMUST00000170460.1
Chkb
choline kinase beta
chr1_+_74506044 0.102 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr7_+_82648595 0.096 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
Eftud1


elongation factor Tu GTP binding domain containing 1


chr14_+_57798182 0.085 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr4_+_129461581 0.082 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr19_-_5688149 0.070 ENSMUST00000068169.5
Pcnxl3
pecanex-like 3 (Drosophila)
chr3_+_58526303 0.065 ENSMUST00000138848.1
Eif2a
eukaryotic translation initiation factor 2A
chr10_+_13008442 0.054 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr14_+_20674311 0.042 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr15_-_89425795 0.035 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr14_+_57798620 0.017 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr17_-_34028044 0.007 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-Ke6

H2-K region expressed gene 6

chr4_+_117251951 0.006 ENSMUST00000062824.5
Tmem53
transmembrane protein 53
chr2_+_22895583 0.002 ENSMUST00000152170.1
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.6 3.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.6 1.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 1.5 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 1.0 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.3 1.3 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.3 0.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 0.8 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.2 0.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 1.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 3.1 GO:0001553 luteinization(GO:0001553)
0.2 1.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 1.0 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 0.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.0 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 3.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:2000097 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.4 GO:0015879 carnitine transport(GO:0015879)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.5 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 9.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 1.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0043173 nucleotide salvage(GO:0043173)
0.0 1.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 1.0 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 3.8 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.3 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 3.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0072534 perineuronal net(GO:0072534)
0.7 3.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 3.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 7.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 8.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.7 GO:0061574 ASAP complex(GO:0061574)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.6 GO:0071565 nBAF complex(GO:0071565)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.0 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 1.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 1.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.7 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 3.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.6 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 3.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.0 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 3.8 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.0 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 1.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.0 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 3.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol