Motif ID: Nr2f1_Nr4a1
Z-value: 0.627
Transcription factors associated with Nr2f1_Nr4a1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2f1 | ENSMUSG00000069171.7 | Nr2f1 |
Nr4a1 | ENSMUSG00000023034.6 | Nr4a1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2f1 | mm10_v2_chr13_-_78196373_78196440 | -0.23 | 1.7e-01 | Click! |
Nr4a1 | mm10_v2_chr15_+_101266839_101266859 | -0.15 | 3.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
0.7 | 0.7 | GO:0097491 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) |
0.6 | 2.4 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
0.6 | 1.8 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
0.4 | 1.2 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.4 | 1.2 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
0.3 | 0.7 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
0.3 | 0.9 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.3 | 0.9 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
0.3 | 1.4 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
0.3 | 1.4 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.3 | 0.8 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.3 | 1.1 | GO:0032275 | luteinizing hormone secretion(GO:0032275) |
0.3 | 0.8 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.3 | 2.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.3 | 0.8 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.3 | 0.8 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
0.2 | 1.3 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.2 | 0.9 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
0.2 | 0.8 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.2 | 0.6 | GO:1904347 | intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770) |
0.2 | 1.0 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.2 | 0.5 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.2 | 1.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.2 | 1.4 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.2 | 0.8 | GO:1903275 | positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) |
0.2 | 1.0 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.2 | 0.6 | GO:0014831 | gastro-intestinal system smooth muscle contraction(GO:0014831) |
0.2 | 2.2 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.2 | 0.5 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.2 | 0.6 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
0.1 | 0.4 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.1 | 0.4 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.4 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.1 | 0.4 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.1 | 0.7 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.1 | 0.4 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.1 | 0.7 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 1.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.1 | 0.4 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
0.1 | 3.3 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.1 | 2.8 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 1.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.4 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308) |
0.1 | 0.7 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.1 | 0.4 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.1 | 0.3 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.1 | 0.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.1 | 0.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 2.1 | GO:0001553 | luteinization(GO:0001553) |
0.1 | 0.6 | GO:0032493 | response to bacterial lipoprotein(GO:0032493) |
0.1 | 0.3 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.1 | 0.3 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
0.1 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.1 | 0.5 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.1 | 0.8 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
0.1 | 0.2 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.1 | 0.3 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
0.1 | 0.3 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.1 | 0.3 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
0.1 | 0.3 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) |
0.1 | 0.3 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
0.1 | 0.4 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.1 | 0.2 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
0.1 | 0.3 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.1 | 0.2 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
0.1 | 0.2 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.1 | 0.6 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.1 | 0.2 | GO:0046078 | dUMP metabolic process(GO:0046078) |
0.1 | 0.3 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
0.1 | 0.5 | GO:0090234 | cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234) |
0.1 | 0.2 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.1 | 0.2 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
0.1 | 0.7 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.1 | 0.3 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.1 | 0.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 0.3 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 3.2 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.1 | 0.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.1 | 0.2 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.1 | 0.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.1 | 0.2 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.1 | 0.7 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.1 | 1.7 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
0.1 | 1.1 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.1 | 0.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.1 | 0.4 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.1 | 1.0 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.5 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
0.1 | 0.3 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
0.1 | 0.2 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
0.1 | 1.1 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 1.8 | GO:0014047 | glutamate secretion(GO:0014047) |
0.1 | 0.1 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 0.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.2 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
0.1 | 0.6 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 0.4 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.1 | 0.8 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.1 | 0.8 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
0.1 | 0.4 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
0.1 | 0.7 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.1 | 0.3 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
0.1 | 0.1 | GO:0032847 | regulation of cellular pH reduction(GO:0032847) |
0.1 | 0.2 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.1 | 0.1 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
0.1 | 0.2 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
0.1 | 0.4 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 0.3 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.1 | 0.3 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.5 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.0 | 0.1 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.0 | 0.5 | GO:0046512 | sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 1.1 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 2.6 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.6 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
0.0 | 0.1 | GO:0097112 | gamma-aminobutyric acid receptor clustering(GO:0097112) |
0.0 | 0.1 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.0 | 0.3 | GO:0051665 | membrane raft localization(GO:0051665) |
0.0 | 0.1 | GO:0050787 | glycolate metabolic process(GO:0009441) enzyme active site formation(GO:0018307) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.0 | 0.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.0 | 0.3 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.0 | 0.6 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
0.0 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.0 | 0.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
0.0 | 0.2 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.0 | 0.2 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.0 | 0.6 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.1 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.0 | 0.1 | GO:0003360 | brainstem development(GO:0003360) |
0.0 | 0.1 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.0 | 0.1 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
0.0 | 0.5 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
0.0 | 0.7 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
0.0 | 0.3 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 0.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
0.0 | 0.2 | GO:0046135 | pyrimidine nucleoside catabolic process(GO:0046135) |
0.0 | 1.0 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 0.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.3 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
0.0 | 0.4 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.6 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.1 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.0 | 0.5 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.1 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
0.0 | 1.0 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.0 | 0.2 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.0 | 0.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.0 | 0.1 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.0 | 0.2 | GO:0019695 | choline metabolic process(GO:0019695) |
0.0 | 0.5 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.1 | GO:0021586 | pons maturation(GO:0021586) |
0.0 | 0.6 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.0 | 0.4 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
0.0 | 0.2 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 0.1 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.0 | 0.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.0 | 0.1 | GO:0050904 | diapedesis(GO:0050904) |
0.0 | 0.3 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.5 | GO:0018195 | peptidyl-arginine modification(GO:0018195) |
0.0 | 0.5 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.2 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 1.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.5 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.1 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.0 | 0.5 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
0.0 | 0.4 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.1 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
0.0 | 0.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.1 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.0 | 0.5 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.4 | GO:0060080 | inhibitory postsynaptic potential(GO:0060080) |
0.0 | 0.2 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
0.0 | 0.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.0 | 0.2 | GO:0031000 | response to caffeine(GO:0031000) |
0.0 | 0.1 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.4 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.0 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.2 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.0 | 0.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.0 | 1.1 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 0.3 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.0 | 0.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.0 | 1.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 0.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.1 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.1 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 1.1 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.0 | 0.2 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.1 | GO:1902969 | mitotic DNA replication(GO:1902969) |
0.0 | 0.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.1 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
0.0 | 0.6 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.0 | 0.0 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
0.0 | 0.7 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.1 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
0.0 | 0.1 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
0.0 | 1.0 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
0.0 | 0.1 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.0 | 0.8 | GO:0046785 | microtubule polymerization(GO:0046785) |
0.0 | 0.1 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
0.0 | 0.0 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.0 | 0.8 | GO:0050807 | regulation of synapse organization(GO:0050807) |
0.0 | 0.1 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
0.0 | 0.5 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.2 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
0.0 | 0.1 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.0 | 2.0 | GO:0006457 | protein folding(GO:0006457) |
0.0 | 0.0 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.0 | 0.2 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.0 | 0.4 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.1 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 0.4 | GO:2000279 | negative regulation of DNA biosynthetic process(GO:2000279) |
0.0 | 0.1 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.0 | 0.3 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
0.0 | 0.4 | GO:0045471 | response to ethanol(GO:0045471) |
0.0 | 0.0 | GO:0060003 | copper ion export(GO:0060003) cellular response to manganese ion(GO:0071287) |
0.0 | 0.2 | GO:0015858 | nucleoside transport(GO:0015858) |
0.0 | 0.1 | GO:0071456 | cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456) |
0.0 | 0.2 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
0.0 | 0.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.4 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.5 | 1.4 | GO:0098855 | HCN channel complex(GO:0098855) |
0.3 | 1.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.3 | 1.5 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.3 | 1.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.2 | 2.1 | GO:0097427 | microtubule bundle(GO:0097427) |
0.2 | 3.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.2 | 0.8 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.2 | 0.6 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
0.2 | 0.7 | GO:0090537 | CERF complex(GO:0090537) |
0.1 | 0.4 | GO:0098803 | respiratory chain complex(GO:0098803) |
0.1 | 1.0 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.7 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 1.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 1.1 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 1.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 1.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.8 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.1 | 0.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.1 | 1.2 | GO:0009986 | cell surface(GO:0009986) |
0.1 | 0.8 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.1 | 0.2 | GO:1990812 | growth cone filopodium(GO:1990812) |
0.1 | 0.3 | GO:0032280 | symmetric synapse(GO:0032280) |
0.1 | 1.1 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 0.3 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.1 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 1.8 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.1 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.4 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.1 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.7 | GO:0043679 | axon terminus(GO:0043679) |
0.1 | 0.2 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.1 | 0.3 | GO:0097444 | spine apparatus(GO:0097444) |
0.1 | 0.2 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
0.1 | 0.2 | GO:0031983 | vesicle lumen(GO:0031983) |
0.1 | 0.5 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 0.2 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.1 | GO:0072534 | perineuronal net(GO:0072534) |
0.0 | 1.3 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.0 | 0.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.2 | GO:0070069 | cytochrome complex(GO:0070069) |
0.0 | 0.2 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.0 | 0.1 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.0 | 0.6 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.3 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.1 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.9 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.0 | 1.4 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.2 | GO:0032009 | early phagosome(GO:0032009) |
0.0 | 0.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.0 | 0.1 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.3 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 0.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.0 | 0.1 | GO:1902710 | GABA receptor complex(GO:1902710) |
0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 1.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.2 | GO:0097452 | GAIT complex(GO:0097452) |
0.0 | 1.1 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 0.4 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.1 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 2.0 | GO:0005930 | axoneme(GO:0005930) |
0.0 | 0.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 2.2 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 2.5 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.1 | GO:0005745 | m-AAA complex(GO:0005745) |
0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.0 | 1.2 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.1 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.0 | 1.7 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 3.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 1.6 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.2 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 0.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.1 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.1 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.3 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.3 | GO:0032590 | dendrite membrane(GO:0032590) |
0.0 | 0.8 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 1.0 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.1 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 1.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.2 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0031403 | lithium ion binding(GO:0031403) |
0.5 | 2.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.5 | 1.5 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.5 | 2.5 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
0.5 | 1.5 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.5 | 1.9 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.4 | 1.3 | GO:0030172 | troponin C binding(GO:0030172) |
0.4 | 1.7 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
0.4 | 1.4 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.3 | 2.0 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.3 | 0.9 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.3 | 1.1 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.3 | 0.8 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.3 | 1.0 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.3 | 2.6 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.2 | 0.7 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
0.2 | 1.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.2 | 1.4 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.2 | 1.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.2 | 1.1 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.1 | 2.4 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.4 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.1 | 1.1 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.4 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.1 | 0.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.1 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.7 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.1 | 0.5 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.1 | 0.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.1 | 2.6 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 0.3 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
0.1 | 0.5 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.3 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.1 | 0.3 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.1 | 0.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.1 | 2.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 0.4 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.1 | 0.4 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.1 | 0.9 | GO:0015266 | protein channel activity(GO:0015266) |
0.1 | 0.5 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.1 | 0.4 | GO:0004359 | glutaminase activity(GO:0004359) |
0.1 | 0.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.1 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 0.5 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 0.5 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 0.4 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.1 | 0.2 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.1 | 2.9 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 0.5 | GO:0016936 | galactoside binding(GO:0016936) |
0.1 | 0.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.1 | 1.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 0.8 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.1 | 1.6 | GO:0022839 | ion gated channel activity(GO:0022839) |
0.1 | 0.3 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 0.6 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.1 | 0.3 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.1 | 0.2 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
0.1 | 0.3 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.1 | 0.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.1 | 0.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.4 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.1 | 0.3 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.1 | 0.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 0.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 0.2 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.1 | 0.1 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 1.1 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 1.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.1 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.0 | 1.3 | GO:0017046 | peptide hormone binding(GO:0017046) |
0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.9 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
0.0 | 0.7 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.0 | 0.7 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
0.0 | 0.6 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 1.8 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.0 | 0.1 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.0 | 0.1 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.0 | 0.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.3 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.0 | 0.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.0 | 0.5 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.0 | 0.1 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.0 | 0.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.4 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.9 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.3 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 1.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.1 | GO:0004064 | arylesterase activity(GO:0004064) |
0.0 | 0.3 | GO:0008227 | G-protein coupled amine receptor activity(GO:0008227) |
0.0 | 3.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.5 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 0.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.1 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.9 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.1 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.0 | 0.4 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 3.4 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
0.0 | 0.7 | GO:0015301 | anion:anion antiporter activity(GO:0015301) |
0.0 | 0.1 | GO:0016917 | GABA receptor activity(GO:0016917) |
0.0 | 0.4 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.0 | 1.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 1.1 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.7 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.0 | 0.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.0 | 0.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 0.2 | GO:0048156 | tau protein binding(GO:0048156) |
0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.0 | 0.8 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.0 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.0 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.0 | 0.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.0 | 0.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 0.0 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.0 | 0.6 | GO:0035591 | signaling adaptor activity(GO:0035591) |
0.0 | 0.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.1 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.0 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 4.3 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.5 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 2.7 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 2.5 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 1.0 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.4 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.0 | 1.3 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 2.5 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.8 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 1.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.3 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.3 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.0 | 2.7 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.6 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 1.3 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 0.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.3 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.1 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 0.7 | PID_P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.1 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.2 | 3.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.2 | 2.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.2 | 6.7 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.2 | 1.5 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.2 | 2.0 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.1 | 1.1 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.1 | 0.6 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.1 | 1.8 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 1.0 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 1.0 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.1 | 2.0 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 2.2 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.1 | 0.7 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.1 | 0.4 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
0.1 | 1.1 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.1 | 0.4 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 0.3 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.0 | 0.9 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.6 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 1.1 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 3.1 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.8 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.0 | 1.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.3 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 0.3 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.0 | 2.5 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.6 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
0.0 | 1.7 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.0 | 2.3 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 0.4 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 0.1 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.0 | 1.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.4 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 1.1 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.3 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 0.9 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.2 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
0.0 | 0.5 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.3 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.0 | 0.4 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
0.0 | 0.0 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.0 | 0.1 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 0.8 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 1.6 | REACTOME_SIGNALING_BY_NOTCH1 | Genes involved in Signaling by NOTCH1 |
0.0 | 0.1 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.2 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
0.0 | 0.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.1 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.0 | 0.1 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 0.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.1 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 0.3 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 0.1 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 0.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
0.0 | 0.5 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
0.0 | 0.2 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |