Motif ID: Nr2f1_Nr4a1

Z-value: 0.627

Transcription factors associated with Nr2f1_Nr4a1:

Gene SymbolEntrez IDGene Name
Nr2f1 ENSMUSG00000069171.7 Nr2f1
Nr4a1 ENSMUSG00000023034.6 Nr4a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f1mm10_v2_chr13_-_78196373_78196440-0.231.7e-01Click!
Nr4a1mm10_v2_chr15_+_101266839_101266859-0.153.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f1_Nr4a1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_106656081 2.519 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr2_+_71981184 2.390 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr12_+_61523889 2.226 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr11_+_7063423 2.196 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr15_-_79804717 1.885 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr5_+_63649335 1.851 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr8_+_124793013 1.750 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr1_-_164458345 1.716 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_+_124793061 1.568 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr11_-_3504766 1.520 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr2_-_113217051 1.498 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr2_-_13011747 1.446 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr10_+_79716588 1.430 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr11_-_76577701 1.412 ENSMUST00000176179.1
Abr
active BCR-related gene
chr6_+_91157373 1.319 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr9_-_70141484 1.315 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr17_+_29360923 1.306 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr2_-_59160644 1.294 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr10_-_78464853 1.205 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_-_78464969 1.180 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_+_78574492 1.159 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr5_+_111581422 1.155 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr2_+_126556128 1.152 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr4_+_123183722 1.134 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr2_+_59160838 1.122 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr13_-_92131494 1.122 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr3_-_54915867 1.108 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr15_-_79285502 1.083 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr13_+_94875600 1.063 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr2_+_121357714 1.043 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr15_-_64382908 1.032 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chrX_-_72656135 1.002 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr15_-_44788016 0.985 ENSMUST00000090057.4
ENSMUST00000110269.1
Sybu

syntabulin (syntaxin-interacting)

chr2_-_166155624 0.945 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr11_+_98741805 0.941 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr11_+_42419729 0.941 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr4_+_155734800 0.936 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr19_+_6400523 0.933 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr11_-_81968415 0.926 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr9_+_53771499 0.914 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr6_+_91156665 0.913 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr14_+_64589802 0.887 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr15_-_43170809 0.882 ENSMUST00000063492.6
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr15_-_79505241 0.866 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr8_-_105471481 0.853 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr6_-_137571007 0.838 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr14_-_21848924 0.833 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr4_+_123183456 0.832 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr3_-_109027600 0.831 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr1_-_84696182 0.829 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr6_+_91156772 0.827 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr2_+_170731807 0.826 ENSMUST00000029075.4
Dok5
docking protein 5
chr9_-_22002599 0.824 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr17_+_5492558 0.824 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr14_-_70630149 0.821 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr4_+_138250462 0.820 ENSMUST00000105823.1
Sh2d5
SH2 domain containing 5
chr4_-_36136463 0.820 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr3_+_68572245 0.814 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr10_+_110920170 0.803 ENSMUST00000020403.5
Csrp2
cysteine and glycine-rich protein 2
chr14_-_23803304 0.802 ENSMUST00000179836.1
ENSMUST00000172099.2
ENSMUST00000065788.8
ENSMUST00000179097.1
ENSMUST00000177634.1
ENSMUST00000074983.6
ENSMUST00000163322.2
ENSMUST00000100831.4
Kcnma1







potassium large conductance calcium-activated channel, subfamily M, alpha member 1







chr10_+_21992216 0.797 ENSMUST00000150089.1
ENSMUST00000100036.3
Sgk1

serum/glucocorticoid regulated kinase 1

chr7_+_30712209 0.776 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr8_-_84937347 0.775 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr13_+_98354234 0.770 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr1_+_57845534 0.767 ENSMUST00000169772.1
Spats2l
spermatogenesis associated, serine-rich 2-like
chr7_-_100547620 0.762 ENSMUST00000064334.2
D630004N19Rik
RIKEN cDNA D630004N19 gene
chr11_+_104132841 0.761 ENSMUST00000093925.4
Crhr1
corticotropin releasing hormone receptor 1
chr17_-_35910032 0.760 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr2_-_60963192 0.756 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_+_45896941 0.744 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr4_+_99929414 0.742 ENSMUST00000058351.9
Pgm2
phosphoglucomutase 2
chrX_-_162565514 0.738 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr6_+_96115249 0.733 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr9_-_112187766 0.728 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr7_+_45897429 0.727 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr19_-_57118981 0.726 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr2_-_129699833 0.720 ENSMUST00000028883.5
Pdyn
prodynorphin
chr8_+_36457548 0.717 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr1_+_75382114 0.710 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr6_+_71707561 0.709 ENSMUST00000121469.1
Reep1
receptor accessory protein 1
chr12_+_109743787 0.709 ENSMUST00000183068.1
Mirg
miRNA containing gene
chr2_-_112480817 0.703 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr9_-_110742577 0.689 ENSMUST00000006005.7
Pth1r
parathyroid hormone 1 receptor
chr4_+_42916647 0.687 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr7_-_98162318 0.687 ENSMUST00000107112.1
Capn5
calpain 5
chr3_+_68468162 0.683 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr7_-_74554474 0.682 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr19_+_6401675 0.676 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr7_-_4522427 0.675 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr9_-_107710475 0.668 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_13494479 0.659 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr7_-_4522794 0.658 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr1_+_75375271 0.651 ENSMUST00000087122.5
Speg
SPEG complex locus
chr14_+_4023941 0.650 ENSMUST00000096184.4
Gm5796
predicted gene 5796
chr7_-_109616548 0.647 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr6_-_119544282 0.641 ENSMUST00000119369.1
ENSMUST00000178696.1
Wnt5b

wingless-related MMTV integration site 5B

chr3_+_118433797 0.635 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr5_-_103100054 0.627 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr3_+_68584154 0.626 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr15_+_84669565 0.621 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr12_+_108334341 0.620 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr4_+_99955715 0.619 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr7_-_31126945 0.616 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr10_-_81600857 0.615 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr8_-_46294592 0.615 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr1_-_136260873 0.610 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chrX_-_136203637 0.597 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr19_-_46327121 0.594 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr11_-_42000284 0.591 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr9_-_112187898 0.590 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_+_166254095 0.586 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr19_+_53529100 0.585 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr4_+_138250403 0.578 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr3_-_59210881 0.574 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr9_+_109931774 0.574 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr12_-_111672290 0.564 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr1_-_140183404 0.562 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr15_+_85510812 0.559 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr5_-_5265224 0.557 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr16_+_41532999 0.557 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chr19_+_6399746 0.554 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr11_-_74590065 0.549 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr11_-_74590186 0.549 ENSMUST00000102521.1
Rap1gap2
RAP1 GTPase activating protein 2
chr12_-_67221221 0.538 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr1_+_75400070 0.537 ENSMUST00000113589.1
Speg
SPEG complex locus
chr4_-_45108038 0.536 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr13_-_102958084 0.529 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr7_+_4925802 0.518 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr4_+_116075269 0.514 ENSMUST00000030471.8
Lrrc41
leucine rich repeat containing 41
chr7_-_19715395 0.514 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr19_+_6399857 0.512 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr7_-_100514800 0.508 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr19_-_47090610 0.506 ENSMUST00000096014.3
Usmg5
upregulated during skeletal muscle growth 5
chr2_+_144599897 0.505 ENSMUST00000028917.6
Dtd1
D-tyrosyl-tRNA deacylase 1
chr11_-_42000532 0.501 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_+_91082362 0.498 ENSMUST00000169852.1
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr17_-_83631892 0.495 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr7_-_98309471 0.494 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr19_-_5085483 0.488 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr4_+_102254739 0.485 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr3_-_95142346 0.481 ENSMUST00000013851.3
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
chr17_-_35909626 0.480 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr1_-_120074023 0.479 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr1_-_87573825 0.478 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr2_+_121358591 0.478 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr18_+_62548911 0.477 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr1_+_36691487 0.476 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr17_-_87446854 0.473 ENSMUST00000040440.6
Calm2
calmodulin 2
chr10_-_20725023 0.473 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr10_+_21993890 0.472 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr2_+_140170641 0.471 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr1_+_137966529 0.469 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr10_-_42478488 0.467 ENSMUST00000041024.8
Lace1
lactation elevated 1
chr4_+_47288287 0.466 ENSMUST00000146967.1
Col15a1
collagen, type XV, alpha 1
chr8_+_108714644 0.465 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr11_-_69822144 0.465 ENSMUST00000045771.6
Spem1
sperm maturation 1
chr14_-_20794009 0.464 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr7_+_28833975 0.462 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr8_+_34327910 0.459 ENSMUST00000075321.6
Gm4889
predicted gene 4889
chr6_-_89595647 0.458 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr17_+_27655572 0.452 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr11_+_121702591 0.444 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr1_-_124045247 0.440 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr1_-_86359455 0.440 ENSMUST00000027438.6
Ncl
nucleolin
chr2_-_26021679 0.436 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chr19_-_4989964 0.432 ENSMUST00000056129.7
Npas4
neuronal PAS domain protein 4
chr14_+_58070547 0.431 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr11_-_4704334 0.430 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr6_-_138422898 0.429 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr13_-_73328442 0.428 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr6_-_91473361 0.427 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr19_-_57197435 0.426 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_57314896 0.426 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr4_-_139131058 0.426 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr6_-_59426279 0.425 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr7_-_31055594 0.425 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr10_-_89257578 0.425 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chr2_+_92375306 0.424 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chr6_+_90550789 0.422 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr3_-_36690118 0.422 ENSMUST00000029271.4
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr4_-_35845204 0.422 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr11_-_109472611 0.422 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr6_-_119467210 0.422 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr4_-_119538769 0.421 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr4_-_130174691 0.420 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr12_-_111966954 0.418 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr5_-_103211251 0.416 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr2_-_180042401 0.414 ENSMUST00000029082.8
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr1_-_140183283 0.413 ENSMUST00000111977.1
Cfh
complement component factor h
chr17_+_55445375 0.411 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr7_-_74554726 0.408 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr12_-_54656496 0.407 ENSMUST00000056228.6
Sptssa
serine palmitoyltransferase, small subunit A
chr7_-_141429433 0.407 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr17_-_46032366 0.403 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr7_-_31054815 0.399 ENSMUST00000071697.4
ENSMUST00000108110.3
Fxyd1

FXYD domain-containing ion transport regulator 1

chr19_-_57197377 0.399 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr1_+_63176818 0.392 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr9_+_87015537 0.391 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr16_-_44139196 0.385 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr1_-_134235420 0.384 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.7 0.7 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.6 2.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.6 1.8 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.4 1.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 0.7 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.3 0.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.3 0.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 1.4 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.3 1.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.3 0.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.3 1.1 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.3 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.3 2.4 GO:0071420 cellular response to histamine(GO:0071420)
0.3 0.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.3 0.8 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.2 1.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 0.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.6 GO:1904347 intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
0.2 1.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.5 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.4 GO:0019388 galactose catabolic process(GO:0019388)
0.2 0.8 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.2 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.6 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.2 2.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.6 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.4 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 3.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 2.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.1 0.7 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.4 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.1 0.3 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 2.1 GO:0001553 luteinization(GO:0001553)
0.1 0.6 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.3 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.3 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.1 0.3 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.1 0.3 GO:2000331 regulation of terminal button organization(GO:2000331)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.5 GO:0090234 cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 3.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.7 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.5 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 0.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.1 1.1 GO:0010107 potassium ion import(GO:0010107)
0.1 1.8 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.4 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.3 GO:0046103 inosine biosynthetic process(GO:0046103)
0.1 0.1 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.5 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 1.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 2.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation(GO:0018307) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.6 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.0 0.5 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0021586 pons maturation(GO:0021586)
0.0 0.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.4 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 1.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.0 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 1.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.8 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.1 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 2.0 GO:0006457 protein folding(GO:0006457)
0.0 0.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.0 GO:0060003 copper ion export(GO:0060003) cellular response to manganese ion(GO:0071287)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.5 1.4 GO:0098855 HCN channel complex(GO:0098855)
0.3 1.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 1.5 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.1 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 0.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.2 0.7 GO:0090537 CERF complex(GO:0090537)
0.1 0.4 GO:0098803 respiratory chain complex(GO:0098803)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0001651 dense fibrillar component(GO:0001651)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 1.2 GO:0009986 cell surface(GO:0009986)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.7 GO:0043679 axon terminus(GO:0043679)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.2 GO:0005902 microvillus(GO:0005902)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:1902710 GABA receptor complex(GO:1902710)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.0 GO:0005930 axoneme(GO:0005930)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 3.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0031403 lithium ion binding(GO:0031403)
0.5 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.5 1.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.5 2.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 1.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5 1.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 1.3 GO:0030172 troponin C binding(GO:0030172)
0.4 1.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 1.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 2.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 0.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.3 1.1 GO:0001851 complement component C3b binding(GO:0001851)
0.3 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 2.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 0.7 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.2 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 2.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.4 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 2.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.9 GO:0015266 protein channel activity(GO:0015266)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 2.9 GO:0030552 cAMP binding(GO:0030552)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.6 GO:0022839 ion gated channel activity(GO:0022839)
0.1 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 1.3 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.7 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 3.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.1 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.0 2.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 2.5 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.0 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 3.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 2.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 6.7 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 1.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.0 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 0.6 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.0 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 0.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.1 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.4 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 3.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 2.3 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.1 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.6 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.1 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.1 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.5 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds