Motif ID: Nr3c2

Z-value: 0.382


Transcription factors associated with Nr3c2:

Gene SymbolEntrez IDGene Name
Nr3c2 ENSMUSG00000031618.7 Nr3c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c2mm10_v2_chr8_+_76902277_76902476-0.163.3e-01Click!


Activity profile for motif Nr3c2.

activity profile for motif Nr3c2


Sorted Z-values histogram for motif Nr3c2

Sorted Z-values for motif Nr3c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr3c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_101448403 1.561 ENSMUST00000010502.6
 Ifi35
interferon-induced protein 35
chr9_+_123366921 1.384 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr14_-_8309770 1.102 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
 Fam107a


family with sequence similarity 107, member A


chr6_-_6882068 1.033 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr8_+_94179089 0.956 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr3_-_95904683 0.918 ENSMUST00000147962.1
ENSMUST00000036181.8
 Car14

carbonic anhydrase 14

chr10_+_26822560 0.849 ENSMUST00000135866.1
 Arhgap18
Rho GTPase activating protein 18
chr5_+_112288734 0.834 ENSMUST00000151947.1
 Tpst2
protein-tyrosine sulfotransferase 2
chr2_+_172472512 0.701 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr8_+_71406003 0.662 ENSMUST00000119976.1
ENSMUST00000120725.1
 Ankle1

ankyrin repeat and LEM domain containing 1

chr1_-_74935549 0.519 ENSMUST00000094844.3
 Ccdc108
coiled-coil domain containing 108
chr1_-_171240055 0.380 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr8_+_70697739 0.317 ENSMUST00000095267.4
 Jund
Jun proto-oncogene related gene d
chr15_-_97020322 0.279 ENSMUST00000166223.1
 Slc38a4
solute carrier family 38, member 4
chr10_-_117282262 0.268 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr3_-_88739692 0.268 ENSMUST00000090946.2
 Gm10253
predicted gene 10253
chr13_+_99100698 0.220 ENSMUST00000181742.1
 Gm807
predicted gene 807
chr14_+_70530819 0.195 ENSMUST00000047331.6
 Lgi3
leucine-rich repeat LGI family, member 3
chr6_-_69631933 0.151 ENSMUST00000177697.1
 Igkv4-54
immunoglobulin kappa chain variable 4-54
chr16_+_38346986 0.144 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
 Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr5_+_123142187 0.099 ENSMUST00000174836.1
ENSMUST00000163030.2
 Setd1b

SET domain containing 1B

chr4_-_149137536 0.097 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
 Apitd1



apoptosis-inducing, TAF9-like domain 1



chr16_-_96192222 0.089 ENSMUST00000113804.1
ENSMUST00000054855.7
 Lca5l

Leber congenital amaurosis 5-like

chr4_-_9643638 0.081 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr5_-_31697598 0.081 ENSMUST00000031018.7
 Rbks
ribokinase
chr10_-_14718191 0.073 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1
chr6_-_69400097 0.064 ENSMUST00000177795.1
 Igkv4-62
immunoglobulin kappa variable 4-62
chr11_+_69098937 0.043 ENSMUST00000021271.7
 Per1
period circadian clock 1
chr15_-_82047579 0.035 ENSMUST00000166578.1
ENSMUST00000080622.7
 Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chr15_+_102102926 0.022 ENSMUST00000169627.1
ENSMUST00000046144.9
 Tenc1

tensin like C1 domain-containing phosphatase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060166 olfactory pit development(GO:0060166)
0.3 0.8 GO:0060468 prevention of polyspermy(GO:0060468)
0.2 0.7 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 1.0 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.1 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling