Motif ID: Nr5a2

Z-value: 0.778


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_77347816 3.425 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr8_+_124793013 2.916 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr8_+_124793061 2.859 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr9_-_77347787 2.682 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr15_-_79804717 2.514 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr3_-_54915867 2.337 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr2_+_121357714 2.202 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr19_+_6400523 2.111 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr10_+_79716588 2.091 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr9_-_77347889 2.085 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr19_-_57314896 1.982 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr11_+_67586520 1.949 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr2_+_121358591 1.825 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr17_-_83631892 1.800 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr11_+_67586675 1.800 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr10_-_125328957 1.791 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_-_134235420 1.741 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr13_-_56296551 1.682 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr19_-_46327121 1.671 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr11_+_98741805 1.661 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr9_-_107710475 1.659 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr16_+_18776839 1.525 ENSMUST00000043577.1
Cldn5
claudin 5
chr4_+_42917234 1.503 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr4_+_42916647 1.466 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr4_+_13751297 1.464 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_37955544 1.427 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr18_+_37955685 1.403 ENSMUST00000169498.2
Rell2
RELT-like 2
chr15_+_3270767 1.389 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr11_+_42419729 1.389 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr11_-_3504766 1.348 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr11_-_4704334 1.331 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_+_6399746 1.327 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr19_+_6399857 1.317 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chrX_-_72656135 1.312 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr6_-_113501818 1.311 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr11_-_109298066 1.260 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr1_+_131970589 1.233 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr13_-_102958084 1.223 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr4_-_116017854 1.211 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr8_+_46490968 1.192 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr7_+_46847128 1.184 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr7_-_110862944 1.158 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_109298121 1.151 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr15_+_84669565 1.113 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr2_+_140170641 1.102 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr2_-_64975762 1.093 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr3_-_107517321 1.083 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr9_-_70141484 1.072 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr15_-_79285502 1.056 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr7_-_4522427 1.050 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr2_-_166155624 1.012 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr10_-_78464969 1.001 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_+_6415443 0.996 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr6_-_135168162 0.980 ENSMUST00000045855.7
Hebp1
heme binding protein 1
chr1_+_45981548 0.949 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr11_+_69088490 0.947 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr3_+_14886426 0.921 ENSMUST00000029078.7
Car2
carbonic anhydrase 2
chr1_-_167393826 0.914 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr16_-_91931643 0.914 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr4_-_139131058 0.898 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr14_-_21848924 0.896 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr6_-_91473361 0.883 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr15_+_85510812 0.881 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr10_-_78464853 0.879 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr15_-_64382908 0.846 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr12_-_86988676 0.845 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr7_-_105482197 0.829 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr19_+_6400611 0.824 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr12_-_67221221 0.816 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr10_-_89257578 0.812 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chr4_+_138250403 0.809 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr6_-_113531575 0.808 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr19_-_7217549 0.802 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr14_+_34170640 0.798 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr10_+_14523062 0.790 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr7_-_100547620 0.779 ENSMUST00000064334.2
D630004N19Rik
RIKEN cDNA D630004N19 gene
chr15_+_85116829 0.778 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr2_+_19658055 0.778 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chr7_-_46179929 0.777 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr11_+_120484613 0.773 ENSMUST00000043627.7
Mrpl12
mitochondrial ribosomal protein L12
chr14_-_77252327 0.769 ENSMUST00000099431.4
Gm10132
predicted gene 10132
chr2_+_32628390 0.737 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr13_-_21501418 0.737 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr11_+_58948890 0.733 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chrX_+_142825698 0.732 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chr7_+_100493795 0.731 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_100494044 0.728 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_-_5085483 0.723 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chrM_+_8600 0.710 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr4_+_138250462 0.700 ENSMUST00000105823.1
Sh2d5
SH2 domain containing 5
chr11_-_59839745 0.696 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr14_+_32321987 0.695 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr7_-_19665005 0.693 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr1_-_171222508 0.692 ENSMUST00000005817.2
Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr9_-_106685653 0.680 ENSMUST00000163441.1
Tex264
testis expressed gene 264
chr6_+_30541582 0.678 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr11_-_59839828 0.675 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr11_-_69560186 0.672 ENSMUST00000004036.5
Efnb3
ephrin B3
chr19_+_8591254 0.662 ENSMUST00000010251.3
ENSMUST00000170817.1
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr2_-_73911323 0.650 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr1_-_52091066 0.643 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr5_+_117363513 0.641 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr1_+_75546258 0.637 ENSMUST00000124341.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr6_+_90550789 0.636 ENSMUST00000130418.1
ENSMUST00000032175.8
Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr9_+_107296843 0.625 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr7_-_141429351 0.621 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr6_-_59426279 0.620 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr9_-_107668967 0.604 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr19_+_57611020 0.598 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr1_+_36691487 0.598 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr19_-_47090610 0.592 ENSMUST00000096014.3
Usmg5
upregulated during skeletal muscle growth 5
chr6_+_91157373 0.577 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chrX_-_141874870 0.575 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr12_+_105032638 0.563 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr7_-_142576492 0.559 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr10_-_11082287 0.555 ENSMUST00000105561.2
ENSMUST00000044306.6
Grm1

glutamate receptor, metabotropic 1

chr17_+_24470393 0.553 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr1_-_120074023 0.547 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr1_-_171222435 0.545 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
Tomm40l


translocase of outer mitochondrial membrane 40 homolog-like (yeast)


chr4_-_45108038 0.542 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr17_-_25868727 0.541 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr19_-_5366626 0.535 ENSMUST00000025762.8
Banf1
barrier to autointegration factor 1
chr19_-_5366285 0.535 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr17_-_35916323 0.532 ENSMUST00000172642.1
ENSMUST00000174807.1
ENSMUST00000174349.1
ENSMUST00000025305.9
ENSMUST00000113782.3
Mrps18b




mitochondrial ribosomal protein S18B




chr14_-_103844173 0.531 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr19_-_3912711 0.530 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr15_-_35938009 0.528 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr13_-_52929458 0.527 ENSMUST00000123599.1
Auh
AU RNA binding protein/enoyl-coenzyme A hydratase
chr8_-_13494479 0.518 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr18_+_6332587 0.517 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr8_+_120668222 0.516 ENSMUST00000034276.6
ENSMUST00000181586.1
Cox4i1

cytochrome c oxidase subunit IV isoform 1

chr8_+_71464910 0.514 ENSMUST00000048914.6
Mrpl34
mitochondrial ribosomal protein L34
chr4_-_119538769 0.511 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr9_-_53975246 0.506 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr11_+_74619594 0.506 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr19_-_60874526 0.499 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr7_-_141429433 0.498 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr4_-_36136463 0.497 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr11_-_53430779 0.496 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr2_-_157566319 0.496 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr1_-_51941261 0.490 ENSMUST00000097103.3
Gm8420
predicted gene 8420
chr6_+_91156772 0.488 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr1_+_75546449 0.486 ENSMUST00000150142.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr14_+_58072686 0.483 ENSMUST00000022545.7
Fgf9
fibroblast growth factor 9
chr2_-_84678051 0.483 ENSMUST00000053664.8
ENSMUST00000111664.1
Tmx2

thioredoxin-related transmembrane protein 2

chr15_+_74563738 0.483 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr6_+_91156665 0.480 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr2_+_30416096 0.472 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr2_+_129593528 0.468 ENSMUST00000049262.7
ENSMUST00000163034.1
ENSMUST00000160276.1
Sirpa


signal-regulatory protein alpha


chr13_-_21787218 0.466 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr9_+_45117813 0.461 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr1_+_135146782 0.457 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr7_+_78783119 0.456 ENSMUST00000032840.4
Mrps11
mitochondrial ribosomal protein S11
chr8_+_120668308 0.453 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chrX_-_71492592 0.449 ENSMUST00000080035.4
Cd99l2
CD99 antigen-like 2
chr8_-_105295934 0.449 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr2_+_178141920 0.447 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr4_+_63558748 0.446 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr11_-_54860564 0.442 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr15_-_77928925 0.434 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
Txn2



thioredoxin 2



chr4_+_140961203 0.433 ENSMUST00000010007.8
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr1_+_75546522 0.429 ENSMUST00000138814.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr2_-_26021679 0.425 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chr2_-_26021532 0.423 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr9_+_54586450 0.422 ENSMUST00000167866.1
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr13_+_119690462 0.412 ENSMUST00000179869.1
Hmgcs1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr8_+_94152607 0.410 ENSMUST00000034211.8
Mt3
metallothionein 3
chr13_+_21787461 0.407 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr1_+_75435930 0.403 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
Gmppa






GDP-mannose pyrophosphorylase A






chr12_-_71136611 0.402 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr2_+_30416031 0.399 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr5_+_24364804 0.398 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr9_+_123150941 0.393 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr4_+_123233556 0.391 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr10_+_80855275 0.389 ENSMUST00000035597.8
Sppl2b
signal peptide peptidase like 2B
chr12_+_12911986 0.386 ENSMUST00000085720.1
Rpl36-ps3
ribosomal protein L36, pseudogene 3
chr9_-_50603792 0.383 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr8_-_70523085 0.381 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
Kxd1



KxDL motif containing 1



chr12_-_34291092 0.380 ENSMUST00000166546.2
Gm18025
predicted gene, 18025
chr15_-_35938186 0.378 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr5_+_34336289 0.377 ENSMUST00000182709.1
ENSMUST00000030992.6
Rnf4

ring finger protein 4

chr10_-_80855187 0.372 ENSMUST00000035775.8
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_63176818 0.367 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr4_-_134535382 0.366 ENSMUST00000116279.3
ENSMUST00000146808.1
Mtfr1l

mitochondrial fission regulator 1-like

chr7_-_100583072 0.366 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr8_-_120668121 0.363 ENSMUST00000034277.7
Emc8
ER membrane protein complex subunit 8
chr4_-_134535047 0.358 ENSMUST00000154769.1
Mtfr1l
mitochondrial fission regulator 1-like
chr8_+_105701624 0.358 ENSMUST00000093195.6
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr8_-_120668058 0.354 ENSMUST00000181950.1
ENSMUST00000181333.1
Emc8
Gm27021
ER membrane protein complex subunit 8
predicted gene, 27021
chr9_-_106891870 0.349 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr9_-_44920698 0.342 ENSMUST00000043675.7
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr7_-_105574324 0.341 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr1_+_181352618 0.339 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr11_+_76407143 0.337 ENSMUST00000021203.6
ENSMUST00000152183.1
Timm22

translocase of inner mitochondrial membrane 22

chr5_-_137611372 0.337 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr2_+_121295437 0.334 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr14_+_25694170 0.332 ENSMUST00000022419.6
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr10_-_62507737 0.330 ENSMUST00000020271.6
Srgn
serglycin
chrX_-_71492799 0.326 ENSMUST00000037391.5
ENSMUST00000114586.2
ENSMUST00000114587.2
Cd99l2


CD99 antigen-like 2


chr12_-_111672290 0.322 ENSMUST00000001304.7
Ckb
creatine kinase, brain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.6 1.7 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.6 1.7 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.6 1.7 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 1.8 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.4 2.1 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.4 1.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 1.1 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.4 1.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4 1.1 GO:0019043 establishment of viral latency(GO:0019043)
0.3 0.7 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 1.9 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 0.9 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.3 0.9 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.3 0.9 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 0.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.3 2.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.3 1.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.7 GO:0019401 alditol biosynthetic process(GO:0019401)
0.2 1.2 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 1.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 5.8 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2 1.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.6 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 8.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 0.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.2 0.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 1.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.3 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.2 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.4 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.1 0.4 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:0046103 inosine biosynthetic process(GO:0046103)
0.1 0.6 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.1 1.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.3 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1 0.3 GO:1902445 negative regulation of oxidative phosphorylation(GO:0090324) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 1.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.6 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 1.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 1.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.1 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 3.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.2 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.7 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.6 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:2000646 negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.4 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.2 GO:0098912 smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 2.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.7 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.6 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 2.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 3.7 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.6 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.7 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0036296 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.0 0.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0098855 HCN channel complex(GO:0098855)
0.3 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 0.8 GO:1990075 periciliary membrane compartment(GO:1990075)
0.2 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.2 2.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 2.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.2 2.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 2.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 1.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.8 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 0.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 7.8 GO:0016605 PML body(GO:0016605)
0.1 0.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 2.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.6 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 3.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 4.0 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 1.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0004111 creatine kinase activity(GO:0004111)
0.6 2.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 1.9 GO:0031403 lithium ion binding(GO:0031403)
0.6 1.7 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.5 2.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 1.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 1.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 1.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.4 1.2 GO:0030172 troponin C binding(GO:0030172)
0.4 1.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 1.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.2 1.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.6 GO:0015288 porin activity(GO:0015288)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.6 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.2 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 4.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.6 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 2.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.6 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0008009 chemokine activity(GO:0008009)
0.1 0.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296) receptor agonist activity(GO:0048018)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 4.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 5.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 1.2 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0004407 histone deacetylase activity(GO:0004407)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 4.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 0.6 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 1.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 2.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.7 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 1.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.9 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 1.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 2.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.7 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 6.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.0 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.4 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 3.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle