Motif ID: Obox1

Z-value: 0.683


Transcription factors associated with Obox1:

Gene SymbolEntrez IDGene Name
Obox1 ENSMUSG00000054310.10 Obox1



Activity profile for motif Obox1.

activity profile for motif Obox1


Sorted Z-values histogram for motif Obox1

Sorted Z-values for motif Obox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_37717122 3.635 ENSMUST00000094836.4
Stk32b
serine/threonine kinase 32B
chr4_+_141368116 3.363 ENSMUST00000006380.4
Fam131c
family with sequence similarity 131, member C
chr9_-_53975246 2.907 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr2_-_104257400 2.772 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr8_-_109251698 2.726 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chrX_-_165327376 2.689 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr4_+_74013442 2.540 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr15_-_84065329 2.496 ENSMUST00000156187.1
Efcab6
EF-hand calcium binding domain 6
chr6_+_58833689 2.238 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr18_-_43393346 2.071 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr10_-_125308809 2.067 ENSMUST00000105257.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr4_-_14621494 2.045 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr12_+_12262139 2.026 ENSMUST00000069066.6
ENSMUST00000069005.8
Fam49a

family with sequence similarity 49, member A

chr11_+_70017199 1.889 ENSMUST00000133140.1
Dlg4
discs, large homolog 4 (Drosophila)
chr12_+_81631369 1.823 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr7_-_134938264 1.823 ENSMUST00000171394.1
Fam196a
family with sequence similarity 196, member A
chr10_-_86732409 1.764 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr9_+_109051090 1.709 ENSMUST00000059097.8
Shisa5
shisa homolog 5 (Xenopus laevis)
chr16_+_17208135 1.688 ENSMUST00000169803.1
Rimbp3
RIMS binding protein 3
chr2_-_24049389 1.667 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 3.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.4 2.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 2.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 2.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5 2.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 2.1 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 2.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.1 1.8 GO:0097186 amelogenesis(GO:0097186)
0.0 1.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.4 1.7 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.1 1.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.4 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.3 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.2 GO:0015747 urate transport(GO:0015747)
0.2 1.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 2.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.2 GO:0002177 manchette(GO:0002177)
0.1 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0014704 intercalated disc(GO:0014704)
0.3 1.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.2 GO:0034709 methylosome(GO:0034709)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.1 1.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 3.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.9 2.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.5 2.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 2.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.0 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.7 GO:0050699 WW domain binding(GO:0050699)
0.2 1.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.5 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.4 GO:0043394 proteoglycan binding(GO:0043394)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.4 1.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 1.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)

Gene overrepresentation in C2:CP category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 3.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 3.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.1 PID_IL27_PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 3.8 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 3.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.8 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 2.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.1 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.2 1.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 1.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.7 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis