Motif ID: Obox3

Z-value: 0.311


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.096.0e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103843154 0.960 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr7_-_4752972 0.551 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
 Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr14_-_69805524 0.537 ENSMUST00000022665.2
 Rhobtb2
Rho-related BTB domain containing 2
chr14_-_19977040 0.537 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977151 0.507 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr4_+_115000174 0.486 ENSMUST00000129957.1
 Stil
Scl/Tal1 interrupting locus
chr18_-_43393346 0.441 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr7_+_35802593 0.433 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr1_-_133701881 0.401 ENSMUST00000167348.1
 Gm17678
predicted gene, 17678
chr2_+_136892168 0.395 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr4_+_115000156 0.383 ENSMUST00000030490.6
 Stil
Scl/Tal1 interrupting locus
chr9_+_62342059 0.375 ENSMUST00000135395.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_62342449 0.352 ENSMUST00000156461.1
 Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_+_74013442 0.349 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr1_+_178187721 0.345 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr6_+_4902913 0.336 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr1_+_118389058 0.334 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
 Clasp1



CLIP associating protein 1



chr14_+_61138445 0.312 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr3_+_55116174 0.289 ENSMUST00000146109.1
 Spg20
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chr14_-_19977249 0.281 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_17727034 0.263 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
 Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr1_-_119836999 0.254 ENSMUST00000163621.1
ENSMUST00000168303.1
 Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chrX_+_74424632 0.245 ENSMUST00000114129.2
ENSMUST00000132749.1
 Ikbkg

inhibitor of kappaB kinase gamma

chr19_+_3767397 0.243 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
 Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chrX_+_52791179 0.230 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr6_-_91807318 0.218 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr4_+_74242468 0.206 ENSMUST00000077851.3
 Kdm4c
lysine (K)-specific demethylase 4C
chr9_+_57825918 0.201 ENSMUST00000165858.1
 Gm17231
predicted gene 17231
chr1_-_52232296 0.198 ENSMUST00000114512.1
 Gls
glutaminase
chr19_+_3768112 0.194 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
 Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr9_-_21312255 0.189 ENSMUST00000115433.3
ENSMUST00000003397.7
 Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr6_-_91807424 0.182 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr13_-_23369156 0.178 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
 Zfp322a


zinc finger protein 322A


chr11_+_70459940 0.173 ENSMUST00000147289.1
ENSMUST00000126105.1
 Zmynd15

zinc finger, MYND-type containing 15

chr9_-_50617228 0.173 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
 AU019823


expressed sequence AU019823


chrX_+_74424534 0.168 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
 Ikbkg



inhibitor of kappaB kinase gamma



chr1_+_140246216 0.166 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr7_+_48789003 0.123 ENSMUST00000118927.1
ENSMUST00000125280.1
 Zdhhc13

zinc finger, DHHC domain containing 13

chr9_+_109051090 0.122 ENSMUST00000059097.8
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr15_+_81663889 0.092 ENSMUST00000023029.8
ENSMUST00000174229.1
ENSMUST00000172748.1
 L3mbtl2


l(3)mbt-like 2 (Drosophila)


chr3_-_63964768 0.085 ENSMUST00000029402.8
 Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr11_+_109649376 0.084 ENSMUST00000106677.1
 Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr9_+_50617516 0.077 ENSMUST00000141366.1
 Pih1d2
PIH1 domain containing 2
chr19_+_3767953 0.075 ENSMUST00000113970.1
 Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr9_+_38719024 0.070 ENSMUST00000129598.1
 Vwa5a
von Willebrand factor A domain containing 5A
chr9_-_50617428 0.065 ENSMUST00000131351.1
ENSMUST00000171462.1
 AU019823

expressed sequence AU019823

chr10_+_111972664 0.063 ENSMUST00000163048.1
ENSMUST00000174653.1
 Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr11_-_70459957 0.053 ENSMUST00000019064.2
 Cxcl16
chemokine (C-X-C motif) ligand 16
chr4_-_15945359 0.039 ENSMUST00000029877.8
 Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr14_-_31640878 0.030 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
 Hacl1


2-hydroxyacyl-CoA lyase 1


chr2_+_152962485 0.025 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr13_+_41001002 0.024 ENSMUST00000046951.9
 Pak1ip1
PAK1 interacting protein 1
chr4_+_62663620 0.024 ENSMUST00000126338.1
 Rgs3
regulator of G-protein signaling 3
chr7_-_44986313 0.023 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
 Prmt1




protein arginine N-methyltransferase 1




chr18_-_60848911 0.005 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
 Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr15_+_76343504 0.002 ENSMUST00000023210.6
 Cyc1
cytochrome c-1
chr2_+_144594054 0.001 ENSMUST00000136628.1
 Gm561
predicted gene 561

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.9 GO:0033504 floor plate development(GO:0033504)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression