Motif ID: Onecut2_Onecut3

Z-value: 0.717

Transcription factors associated with Onecut2_Onecut3:

Gene SymbolEntrez IDGene Name
Onecut2 ENSMUSG00000045991.12 Onecut2
Onecut3 ENSMUSG00000045518.8 Onecut3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Onecut3mm10_v2_chr10_+_80494835_804948730.482.9e-03Click!
Onecut2mm10_v2_chr18_+_64340225_64340364-0.241.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Onecut2_Onecut3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 9.829 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_49636847 7.130 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_109545390 3.830 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr12_+_109544498 3.177 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr4_+_109343029 2.815 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr6_+_5390387 2.669 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chrY_+_897782 2.353 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr9_-_86695897 2.083 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_+_102010138 2.065 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr11_+_46235460 1.774 ENSMUST00000060185.2
Fndc9
fibronectin type III domain containing 9
chr10_-_45470201 1.698 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr4_+_145510759 1.528 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr18_+_50030977 1.400 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr17_+_79051906 1.321 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr13_-_41273977 1.256 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr1_-_64121456 1.196 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr13_-_56895737 1.153 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chrX_+_142825698 1.087 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chr12_+_74297474 1.049 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr1_-_170215380 1.031 ENSMUST00000027979.7
ENSMUST00000123399.1
Uhmk1

U2AF homology motif (UHM) kinase 1

chr7_+_73391160 1.013 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr4_+_43384332 1.003 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr16_-_8672145 0.981 ENSMUST00000008537.8
Carhsp1
calcium regulated heat stable protein 1
chr7_-_34655500 0.968 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr1_+_167598450 0.949 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr12_-_46818749 0.903 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr10_+_69533761 0.888 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr3_+_135212557 0.820 ENSMUST00000062893.7
Cenpe
centromere protein E
chr16_-_28929658 0.791 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr3_-_88455735 0.777 ENSMUST00000029700.5
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_-_97584605 0.738 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr13_-_22041352 0.720 ENSMUST00000102977.2
Hist1h4i
histone cluster 1, H4i
chr2_-_174346712 0.718 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr4_-_97584612 0.711 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_+_10993452 0.711 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr13_-_102906046 0.685 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_136670076 0.684 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr12_+_74288735 0.666 ENSMUST00000095617.1
1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr14_-_20181773 0.657 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr15_+_39076885 0.634 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr9_+_53771499 0.588 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr17_+_21566988 0.586 ENSMUST00000088787.5
Zfp948
zinc finger protein 948
chr16_+_91269759 0.585 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr16_-_23890805 0.579 ENSMUST00000004480.3
Sst
somatostatin
chr10_+_128015157 0.573 ENSMUST00000178041.1
ENSMUST00000026461.7
Prim1

DNA primase, p49 subunit

chr2_+_55411790 0.566 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr6_-_85902528 0.530 ENSMUST00000159755.1
1700019G17Rik
RIKEN cDNA 1700019G17 gene
chr17_+_12119274 0.513 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr3_+_138143888 0.498 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr5_-_52566264 0.493 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr1_-_158958367 0.493 ENSMUST00000159861.2
Pappa2
pappalysin 2
chr9_+_65890237 0.481 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr1_+_167598384 0.458 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr12_+_88083697 0.457 ENSMUST00000177720.1
Gm16368
predicted pseudogene 16368
chr10_+_128790903 0.456 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr4_+_43383449 0.432 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr17_-_90088343 0.431 ENSMUST00000173917.1
Nrxn1
neurexin I
chr7_-_116084635 0.429 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr3_+_138143846 0.428 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr3_+_76075583 0.427 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_+_38339258 0.397 ENSMUST00000143783.2
Lhx2
LIM homeobox protein 2
chr9_-_64253617 0.385 ENSMUST00000005066.8
Map2k1
mitogen-activated protein kinase kinase 1
chr14_+_13454010 0.384 ENSMUST00000112656.2
Synpr
synaptoporin
chrX_+_119927196 0.376 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chrX_-_43274786 0.370 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr17_-_90455872 0.366 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr18_+_35771488 0.352 ENSMUST00000170693.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chrX_-_111536325 0.339 ENSMUST00000156639.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr2_-_65567505 0.338 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chrX_+_106015699 0.329 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr3_+_5218516 0.328 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr1_-_9944103 0.327 ENSMUST00000182498.1
ENSMUST00000182742.1
ENSMUST00000182580.1
Snhg6


small nucleolar RNA host gene (non-protein coding) 6


chr1_-_64121389 0.325 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr15_-_79328201 0.311 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr3_+_106034661 0.309 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr11_-_103017167 0.307 ENSMUST00000021313.2
Dcakd
dephospho-CoA kinase domain containing
chr18_+_35771574 0.296 ENSMUST00000167406.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chr10_+_37139558 0.288 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr11_+_108587077 0.279 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chr13_+_14613242 0.266 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr2_+_144599897 0.263 ENSMUST00000028917.6
Dtd1
D-tyrosyl-tRNA deacylase 1
chr9_-_14782964 0.260 ENSMUST00000034406.3
Ankrd49
ankyrin repeat domain 49
chr15_-_79328154 0.258 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr14_+_47472547 0.257 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr13_-_14613017 0.256 ENSMUST00000015816.3
Mrpl32
mitochondrial ribosomal protein L32
chr3_+_136670679 0.255 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr6_-_122856151 0.253 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chrX_-_95658392 0.251 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr14_+_47472628 0.246 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr1_+_49244616 0.246 ENSMUST00000056879.8
C230029F24Rik
RIKEN cDNA C230029F24 gene
chr15_-_42676967 0.240 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr2_-_25224653 0.234 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr17_+_21657582 0.233 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr5_-_17849783 0.232 ENSMUST00000170051.1
ENSMUST00000165232.1
Cd36

CD36 antigen

chr6_-_115037824 0.230 ENSMUST00000174848.1
ENSMUST00000032461.5
Tamm41

TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)

chr8_-_109251698 0.229 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr12_+_108605757 0.221 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr10_-_53647080 0.219 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr3_-_63851251 0.214 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr15_+_92597104 0.211 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr11_-_101785252 0.211 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr9_+_55326913 0.208 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr17_-_71459300 0.207 ENSMUST00000183937.1
Gm4707
predicted gene 4707
chr12_+_59131473 0.202 ENSMUST00000177162.1
Ctage5
CTAGE family, member 5
chr2_+_36049453 0.201 ENSMUST00000028256.4
Morn5
MORN repeat containing 5
chr5_-_147894804 0.191 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chrX_-_113185485 0.189 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chrX_-_95658379 0.189 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr6_-_42324640 0.180 ENSMUST00000031891.8
ENSMUST00000143278.1
Fam131b

family with sequence similarity 131, member B

chr7_-_89941084 0.171 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr6_-_42324554 0.168 ENSMUST00000095974.3
Fam131b
family with sequence similarity 131, member B
chr18_-_10030017 0.162 ENSMUST00000116669.1
ENSMUST00000092096.6
Usp14

ubiquitin specific peptidase 14

chr15_+_55112317 0.162 ENSMUST00000096433.3
Deptor
DEP domain containing MTOR-interacting protein
chr4_+_11558914 0.159 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr12_+_59131286 0.158 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr18_+_56707725 0.157 ENSMUST00000025486.8
Lmnb1
lamin B1
chr6_-_51469869 0.155 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr9_-_108428484 0.154 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chrX_-_95658416 0.152 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr7_+_119760918 0.146 ENSMUST00000106527.1
ENSMUST00000106528.1
ENSMUST00000063770.3
ENSMUST00000106529.1
Acsm3



acyl-CoA synthetase medium-chain family member 3



chr7_-_89941196 0.146 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr7_-_90475971 0.145 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr15_-_103215285 0.139 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr6_-_92481343 0.137 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr16_-_56712825 0.131 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr2_+_104069819 0.129 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr4_+_155831272 0.120 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr11_+_97315716 0.118 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr1_+_88103229 0.109 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chrX_+_42151002 0.107 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr8_+_93810832 0.101 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr17_+_34564268 0.100 ENSMUST00000015612.7
Notch4
notch 4
chr4_+_147492417 0.096 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr12_+_76765527 0.095 ENSMUST00000137826.1
ENSMUST00000041262.7
ENSMUST00000126408.1
ENSMUST00000110399.2
Fntb
Churc1


farnesyltransferase, CAAX box, beta
churchill domain containing 1


chr13_-_18031616 0.094 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr16_-_4679703 0.091 ENSMUST00000038552.6
ENSMUST00000090480.4
Coro7

coronin 7

chr14_+_113314602 0.085 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr18_-_53744509 0.085 ENSMUST00000049811.6
Cep120
centrosomal protein 120
chr7_+_35802593 0.077 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr9_-_44113470 0.077 ENSMUST00000056328.5
Rnf26
ring finger protein 26
chr6_-_51469836 0.077 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr6_+_127233756 0.075 ENSMUST00000071458.3
Gm4968
predicted gene 4968
chr3_+_5218589 0.075 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr13_+_90923122 0.075 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr15_+_102459028 0.073 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr19_-_4906598 0.072 ENSMUST00000053506.6
Bbs1
Bardet-Biedl syndrome 1 (human)
chr3_-_19265007 0.072 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr9_-_20728219 0.069 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr15_+_102459193 0.068 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr7_+_4792874 0.066 ENSMUST00000032597.5
ENSMUST00000078432.4
Rpl28

ribosomal protein L28

chr5_+_29735688 0.063 ENSMUST00000008733.8
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr19_+_44992127 0.063 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr13_+_49544443 0.063 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr7_+_19119853 0.061 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr14_+_11227511 0.060 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr5_+_32458974 0.060 ENSMUST00000015100.8
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isoform
chr1_-_144177259 0.060 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr5_+_109940426 0.057 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr2_-_128943985 0.053 ENSMUST00000028866.8
Zc3h8
zinc finger CCCH type containing 8
chr5_+_15516489 0.051 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr13_+_66904914 0.050 ENSMUST00000168767.2
Gm10767
predicted gene 10767
chr5_-_129623655 0.045 ENSMUST00000076842.5
Gm6139
predicted gene 6139
chr6_+_48684570 0.044 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr12_-_84698769 0.037 ENSMUST00000095550.2
Syndig1l
synapse differentiation inducing 1 like
chr14_-_122451109 0.037 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr10_-_42018363 0.036 ENSMUST00000162405.1
ENSMUST00000095729.4
ENSMUST00000161081.1
ENSMUST00000160262.2
Armc2



armadillo repeat containing 2



chr6_+_48684544 0.035 ENSMUST00000118802.1
Gimap4
GTPase, IMAP family member 4
chr12_-_34291092 0.035 ENSMUST00000166546.2
Gm18025
predicted gene, 18025
chr9_-_69451035 0.031 ENSMUST00000071565.5
Gm4978
predicted gene 4978
chr4_-_109156610 0.029 ENSMUST00000161363.1
Osbpl9
oxysterol binding protein-like 9
chr8_+_122376676 0.028 ENSMUST00000176629.1
Zc3h18
zinc finger CCCH-type containing 18
chr6_+_29853746 0.026 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr6_+_29694204 0.026 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr1_-_63114516 0.024 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr8_+_4625840 0.022 ENSMUST00000073201.5
Zfp958
zinc finger protein 958
chr2_-_51149100 0.021 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr7_+_19291070 0.012 ENSMUST00000108468.3
Rtn2
reticulon 2 (Z-band associated protein)
chr19_+_44562841 0.012 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr18_-_61259987 0.003 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr2_-_10130638 0.002 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr11_+_120232921 0.002 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr9_+_75051977 0.001 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr11_-_17953861 0.001 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 2.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.4 2.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 7.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3 0.9 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.3 2.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 7.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 2.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 0.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 1.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.6 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 1.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.2 GO:0070543 response to linoleic acid(GO:0070543)
0.1 2.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.2 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.4 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 1.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 1.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.8 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 1.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.0 GO:0089701 U2AF(GO:0089701)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 2.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 8.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069) mRNA CDS binding(GO:1990715)
0.0 2.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 2.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.1 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.4 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 2.2 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 2.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation