Motif ID: Pax2

Z-value: 1.040


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_135212557 5.299 ENSMUST00000062893.7
Cenpe
centromere protein E
chr1_-_82291370 4.448 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr5_-_106458440 4.324 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr4_+_148039035 4.071 ENSMUST00000097788.4
Mthfr
5,10-methylenetetrahydrofolate reductase
chr3_+_159495408 3.722 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chr4_+_148039097 3.511 ENSMUST00000141283.1
Mthfr
5,10-methylenetetrahydrofolate reductase
chr9_-_91365778 3.229 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr12_-_101028983 3.187 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr7_-_37773555 3.181 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr10_+_41519493 3.140 ENSMUST00000019962.8
Cd164
CD164 antigen
chr9_-_91365756 3.129 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr6_+_113531675 2.964 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr12_-_102878406 2.637 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr1_+_106171752 2.594 ENSMUST00000061047.6
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr5_+_64803513 2.536 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr2_+_84839395 2.204 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr6_-_6217023 2.139 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr19_-_7105729 2.103 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr11_-_101171302 2.052 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr11_+_70000578 2.039 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr10_+_127063599 2.034 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr9_-_42124276 1.963 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr16_+_77014069 1.890 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr12_-_4233958 1.881 ENSMUST00000111169.3
ENSMUST00000020981.5
Cenpo

centromere protein O

chr17_+_80944611 1.797 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr17_-_70851710 1.788 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr2_-_169405435 1.781 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr17_+_26715644 1.780 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chrX_+_36328353 1.771 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr3_-_133544390 1.769 ENSMUST00000098603.3
Tet2
tet methylcytosine dioxygenase 2
chr15_+_39198244 1.756 ENSMUST00000082054.5
ENSMUST00000042917.9
Rims2

regulating synaptic membrane exocytosis 2

chr2_+_119897212 1.734 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr13_-_64153194 1.701 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr10_+_127063527 1.689 ENSMUST00000006911.5
Cdk4
cyclin-dependent kinase 4
chr6_+_7555053 1.643 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr5_-_124425572 1.623 ENSMUST00000168651.1
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr14_+_34673888 1.619 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr14_+_34673948 1.604 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr10_+_88091070 1.580 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr11_-_48826500 1.568 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr14_+_31019183 1.561 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr11_-_101170327 1.551 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_-_60581013 1.538 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr2_+_48949495 1.511 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr2_+_126707319 1.510 ENSMUST00000028841.7
ENSMUST00000110416.2
Usp8

ubiquitin specific peptidase 8

chr7_+_134670667 1.506 ENSMUST00000084488.4
Dock1
dedicator of cytokinesis 1
chr14_-_72602945 1.503 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chrX_-_73930751 1.502 ENSMUST00000155597.1
ENSMUST00000114379.1
Renbp

renin binding protein

chr14_-_73325773 1.496 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr19_+_46304709 1.430 ENSMUST00000073116.5
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr14_+_34674122 1.421 ENSMUST00000169910.1
Wapal
wings apart-like homolog (Drosophila)
chrX_-_94123359 1.418 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
Zfx


zinc finger protein X-linked


chr14_+_31019125 1.398 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr11_+_35769462 1.366 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr16_+_5050012 1.357 ENSMUST00000052449.5
Ubn1
ubinuclein 1
chr14_-_18239053 1.345 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr14_+_31019159 1.344 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr2_-_28916412 1.313 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr9_+_46012822 1.296 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr5_-_100500592 1.268 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr13_-_55513427 1.242 ENSMUST00000069929.6
ENSMUST00000069968.6
ENSMUST00000131306.1
ENSMUST00000046246.6
Pdlim7



PDZ and LIM domain 7



chr9_+_46012810 1.240 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr14_+_21500879 1.236 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr10_+_111164794 1.196 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr2_-_26237368 1.194 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chrX_-_73930834 1.168 ENSMUST00000116578.1
Renbp
renin binding protein
chr16_+_94370786 1.129 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr5_+_15934762 1.120 ENSMUST00000115281.2
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr18_+_34861200 1.071 ENSMUST00000165033.1
Egr1
early growth response 1
chr11_-_120630516 1.059 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr6_-_108185552 1.046 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr6_-_39725193 1.016 ENSMUST00000101497.3
Braf
Braf transforming gene
chr2_+_75659253 1.015 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr5_+_15934685 1.014 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr5_-_124425907 1.007 ENSMUST00000065263.5
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr1_-_10232670 1.000 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr2_-_37422869 0.986 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr9_+_70679016 0.961 ENSMUST00000144537.1
Adam10
a disintegrin and metallopeptidase domain 10
chr4_+_128654686 0.960 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr2_-_37703845 0.932 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr11_+_53350783 0.929 ENSMUST00000060945.5
Aff4
AF4/FMR2 family, member 4
chr11_-_120630126 0.923 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr7_-_46795661 0.916 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr10_-_62792243 0.914 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr18_+_36281069 0.908 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chrX_+_50841434 0.893 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr7_+_90130227 0.886 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr17_-_67354459 0.884 ENSMUST00000037974.8
Ptprm
protein tyrosine phosphatase, receptor type, M
chrX_-_94123087 0.875 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr11_-_99230998 0.863 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr5_-_65697856 0.862 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr17_+_56040350 0.834 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr12_+_72441852 0.821 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr19_-_10203880 0.819 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr2_+_71786923 0.810 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr2_+_144368961 0.808 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr16_+_58727910 0.801 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr12_+_72441933 0.791 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr9_-_53667429 0.777 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr16_+_8830093 0.753 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr10_-_62486772 0.745 ENSMUST00000105447.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr7_+_28179469 0.738 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr6_-_39725448 0.724 ENSMUST00000002487.8
Braf
Braf transforming gene
chr19_-_4615453 0.698 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr19_-_4615647 0.691 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr10_-_62486575 0.686 ENSMUST00000092473.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr2_-_28916668 0.679 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr1_+_128244122 0.675 ENSMUST00000027592.3
Ubxn4
UBX domain protein 4
chr9_+_70678950 0.660 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr7_-_126799163 0.658 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr13_+_13590402 0.651 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr9_-_95511897 0.647 ENSMUST00000079659.5
ENSMUST00000078374.6
U2surp

U2 snRNP-associated SURP domain containing

chr4_-_108833608 0.646 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr3_+_116562965 0.645 ENSMUST00000029573.5
Lrrc39
leucine rich repeat containing 39
chr17_+_93199348 0.643 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr11_-_102230127 0.642 ENSMUST00000107150.1
ENSMUST00000156337.1
ENSMUST00000107151.2
ENSMUST00000107152.2
Hdac5



histone deacetylase 5



chr11_-_102230091 0.624 ENSMUST00000008999.5
Hdac5
histone deacetylase 5
chr13_-_64274879 0.617 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr3_+_95318782 0.605 ENSMUST00000139866.1
Cers2
ceramide synthase 2
chr19_-_57008187 0.604 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr16_+_94370618 0.598 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr17_-_33685386 0.586 ENSMUST00000139302.1
ENSMUST00000087582.5
ENSMUST00000114385.2
Hnrnpm


heterogeneous nuclear ribonucleoprotein M


chr1_+_92831614 0.586 ENSMUST00000045970.6
Gpc1
glypican 1
chr7_-_46795881 0.585 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr2_+_119594288 0.568 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr5_-_114773488 0.566 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chrX_+_166344692 0.555 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr10_-_45470201 0.554 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr5_-_114773372 0.554 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr14_+_55560010 0.552 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr19_+_21653302 0.524 ENSMUST00000052556.3
Abhd17b
abhydrolase domain containing 17B
chr10_+_39133981 0.516 ENSMUST00000019991.7
Tube1
epsilon-tubulin 1
chr12_+_4234023 0.513 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr14_-_13961202 0.508 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr3_+_137864573 0.506 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr10_-_63339023 0.506 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
Sirt1


sirtuin 1


chr7_+_127841752 0.503 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr7_-_126799134 0.498 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr2_+_121295437 0.495 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr4_+_127077374 0.494 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr19_-_42779936 0.489 ENSMUST00000069298.6
ENSMUST00000160455.1
ENSMUST00000162004.1
Hps1


Hermansky-Pudlak syndrome 1 homolog (human)


chr2_+_110597298 0.479 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr13_-_64274962 0.474 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr12_-_85374696 0.464 ENSMUST00000040766.7
Tmed10
transmembrane emp24-like trafficking protein 10 (yeast)
chr16_-_96127604 0.463 ENSMUST00000133885.1
ENSMUST00000050884.7
Hmgn1

high mobility group nucleosomal binding domain 1

chr7_+_125707945 0.442 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr4_-_137048695 0.432 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr18_-_31609893 0.424 ENSMUST00000060396.6
Slc25a46
solute carrier family 25, member 46
chr2_+_30286406 0.418 ENSMUST00000138666.1
ENSMUST00000113634.2
Nup188

nucleoporin 188

chr2_+_30286383 0.414 ENSMUST00000064447.5
Nup188
nucleoporin 188
chr15_+_59648644 0.413 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr3_+_90052814 0.406 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik



RIKEN cDNA 4933434E20 gene



chr7_-_16286744 0.395 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr2_+_155381808 0.387 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr9_+_35267857 0.381 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr8_+_92674289 0.378 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr14_-_57746044 0.377 ENSMUST00000173990.1
ENSMUST00000022531.7
Lats2

large tumor suppressor 2

chr15_+_59648350 0.366 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr4_+_48585276 0.363 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_-_133661318 0.343 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr1_-_125912160 0.339 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr1_+_87327044 0.335 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr9_+_44067072 0.333 ENSMUST00000177054.1
Usp2
ubiquitin specific peptidase 2
chr10_-_127211528 0.330 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr9_+_44066993 0.329 ENSMUST00000034508.7
Usp2
ubiquitin specific peptidase 2
chr19_-_7241216 0.328 ENSMUST00000025675.9
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr10_-_29362012 0.321 ENSMUST00000161508.1
Rnf146
ring finger protein 146
chr3_+_137864487 0.301 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr2_-_167492826 0.291 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr4_-_108833544 0.291 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr5_+_24428208 0.284 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr4_+_109000770 0.281 ENSMUST00000106644.2
Nrd1
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr3_-_95882232 0.272 ENSMUST00000161866.1
Gm129
predicted gene 129
chrX_+_106187100 0.269 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr5_+_28165690 0.268 ENSMUST00000036177.7
En2
engrailed 2
chr2_-_121271315 0.268 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chrX_+_68678712 0.266 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1



fragile X mental retardation syndrome 1



chr4_+_109000606 0.263 ENSMUST00000065977.4
ENSMUST00000102736.2
Nrd1

nardilysin, N-arginine dibasic convertase, NRD convertase 1

chr8_+_92674826 0.255 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr3_-_95882193 0.253 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr15_+_66577536 0.252 ENSMUST00000048188.8
Phf20l1
PHD finger protein 20-like 1
chr11_-_52000432 0.244 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr2_-_121271403 0.237 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr17_+_29032664 0.235 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr15_-_79834261 0.231 ENSMUST00000148358.1
Cbx6
chromobox 6
chr10_-_29362032 0.230 ENSMUST00000160372.1
Rnf146
ring finger protein 146
chr7_+_125707893 0.227 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr4_-_126202583 0.224 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr2_+_155382186 0.218 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr4_-_126202757 0.212 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr7_+_19131686 0.209 ENSMUST00000165913.1
Fbxo46
F-box protein 46
chr4_-_58911902 0.208 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
AI314180


expressed sequence AI314180


chr1_+_120602405 0.201 ENSMUST00000079721.7
En1
engrailed 1
chr1_+_87327008 0.200 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr15_-_81399594 0.192 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr2_-_121271341 0.185 ENSMUST00000110647.1
Trp53bp1
transformation related protein 53 binding protein 1
chr11_-_52000748 0.172 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr17_+_83350925 0.169 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
Eml4


echinoderm microtubule associated protein like 4


chr2_+_164833781 0.166 ENSMUST00000143780.1
Ctsa
cathepsin A
chr9_-_35267746 0.163 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0070829 heterochromatin maintenance(GO:0070829)
1.4 4.3 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.0 5.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.9 3.7 GO:0010288 response to lead ion(GO:0010288)
0.9 5.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.6 1.8 GO:0019858 cytosine metabolic process(GO:0019858)
0.6 2.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.5 1.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5 2.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 2.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.5 1.6 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.5 2.6 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
0.5 1.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.5 1.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 3.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 1.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.4 2.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.4 1.1 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.4 1.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 2.0 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.3 1.6 GO:0042117 monocyte activation(GO:0042117)
0.3 1.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 5.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 0.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 1.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of fibroblast migration(GO:0010764)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 0.5 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.2 0.8 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 2.3 GO:0060746 parental behavior(GO:0060746)
0.1 1.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.9 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.4 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 1.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.9 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 4.3 GO:0001709 cell fate determination(GO:0001709)
0.1 1.4 GO:0002467 germinal center formation(GO:0002467)
0.1 6.3 GO:0007628 adult walking behavior(GO:0007628)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.1 GO:0048266 behavioral response to pain(GO:0048266)
0.1 3.2 GO:0031648 protein destabilization(GO:0031648)
0.1 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 2.5 GO:0060351 endochondral ossification(GO:0001958) replacement ossification(GO:0036075) cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 2.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.9 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 2.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 2.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.9 GO:0031290 retina layer formation(GO:0010842) retinal ganglion cell axon guidance(GO:0031290)
0.0 0.4 GO:0090148 membrane fission(GO:0090148)
0.0 0.2 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 2.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.6 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 2.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.0 GO:1904395 synaptic growth at neuromuscular junction(GO:0051124) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.1 GO:0043473 pigmentation(GO:0043473)
0.0 0.4 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0005899 insulin receptor complex(GO:0005899)
0.9 3.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.4 5.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.4 1.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 1.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 1.5 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 0.8 GO:0033186 CAF-1 complex(GO:0033186)
0.2 2.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 5.2 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.8 GO:0001740 Barr body(GO:0001740)
0.1 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0000322 storage vacuole(GO:0000322)
0.1 1.5 GO:0010369 chromocenter(GO:0010369)
0.1 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.0 GO:0016235 aggresome(GO:0016235)
0.0 3.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.5 GO:0031082 BLOC complex(GO:0031082)
0.0 2.8 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.2 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.1 5.3 GO:0043515 kinetochore binding(GO:0043515)
0.5 2.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 4.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 1.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 2.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 3.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.6 GO:0070052 collagen V binding(GO:0070052)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 2.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 0.5 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 1.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 0.8 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 2.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 4.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.6 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 2.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 2.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 12.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 4.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 5.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 1.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 6.4 PID_PLK1_PATHWAY PLK1 signaling events
0.1 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.0 PID_BARD1_PATHWAY BARD1 signaling events
0.1 0.9 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.1 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.5 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 2.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 1.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.3 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.8 PID_CMYB_PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.3 3.0 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 1.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 4.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 2.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 8.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 3.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 3.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 0.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 1.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 3.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 2.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G