Motif ID: Pax6

Z-value: 0.738


Transcription factors associated with Pax6:

Gene SymbolEntrez IDGene Name
Pax6 ENSMUSG00000027168.15 Pax6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax6mm10_v2_chr2_+_105682463_105682547-0.891.0e-13Click!


Activity profile for motif Pax6.

activity profile for motif Pax6


Sorted Z-values histogram for motif Pax6

Sorted Z-values for motif Pax6



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_57118981 6.122 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr19_-_57118897 5.258 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr11_-_95587691 3.095 ENSMUST00000000122.6
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chrX_+_103422010 3.043 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr3_+_65109343 3.005 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr4_+_85205417 2.397 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr1_-_38836090 2.200 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr8_-_57962564 1.980 ENSMUST00000098757.3
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr18_-_34373313 1.797 ENSMUST00000006027.5
Reep5
receptor accessory protein 5
chr15_-_101850778 1.681 ENSMUST00000023790.3
Krt1
keratin 1
chr6_-_60829826 1.645 ENSMUST00000163779.1
Snca
synuclein, alpha
chr2_-_162661075 1.620 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr7_-_12775658 1.452 ENSMUST00000046245.5
Zscan18
zinc finger and SCAN domain containing 18
chr3_-_89245005 1.322 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr3_-_89245159 1.298 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr15_+_84669565 1.277 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr13_-_110280103 1.271 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr10_+_80356459 1.211 ENSMUST00000039836.8
ENSMUST00000105351.1
Plk5

polo-like kinase 5

chr5_+_90903864 1.169 ENSMUST00000075433.6
Cxcl2
chemokine (C-X-C motif) ligand 2
chr13_+_64432479 1.116 ENSMUST00000021939.6
Cdk20
cyclin-dependent kinase 20
chr9_+_15239045 1.115 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr5_-_18360384 1.100 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr5_-_142906702 0.977 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr5_+_112255813 0.967 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
Crybb1


crystallin, beta B1


chr15_+_6299797 0.960 ENSMUST00000159046.1
ENSMUST00000161040.1
Dab2

disabled 2, mitogen-responsive phosphoprotein

chr18_+_37447641 0.877 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr15_+_6299781 0.869 ENSMUST00000078019.6
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr17_-_57059795 0.862 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_-_52452654 0.817 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr2_+_105904629 0.810 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_-_118780324 0.764 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr10_+_94550852 0.757 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr14_+_34170640 0.728 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr16_+_4968936 0.721 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr6_-_124741374 0.673 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr19_+_34290653 0.651 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr6_-_122856151 0.641 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr19_+_6400611 0.637 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr13_-_24937585 0.634 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr6_-_88045190 0.615 ENSMUST00000113596.1
ENSMUST00000113600.3
Rab7

RAB7, member RAS oncogene family

chr2_-_75981967 0.613 ENSMUST00000099994.3
Ttc30a1
tetratricopeptide repeat domain 30A1
chr8_+_95825353 0.561 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr17_+_43016536 0.542 ENSMUST00000024708.4
Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr5_+_149265035 0.522 ENSMUST00000130144.1
ENSMUST00000071130.3
Alox5ap

arachidonate 5-lipoxygenase activating protein

chr11_-_67965631 0.493 ENSMUST00000021287.5
ENSMUST00000126766.1
Wdr16

WD repeat domain 16

chr13_-_113618549 0.490 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr12_+_112976471 0.489 ENSMUST00000165079.1
ENSMUST00000002880.6
Btbd6

BTB (POZ) domain containing 6

chr9_+_50775347 0.489 ENSMUST00000159576.1
Alg9
asparagine-linked glycosylation 9 (alpha 1,2 mannosyltransferase)
chr9_-_10904697 0.474 ENSMUST00000162484.1
Cntn5
contactin 5
chr11_+_67966442 0.426 ENSMUST00000021286.4
ENSMUST00000108675.1
Stx8

syntaxin 8

chr4_-_3835595 0.396 ENSMUST00000138502.1
Rps20
ribosomal protein S20
chr4_-_139832920 0.390 ENSMUST00000174681.1
Pax7
paired box gene 7
chr5_+_123907175 0.389 ENSMUST00000023869.8
Denr
density-regulated protein
chr13_-_66905322 0.373 ENSMUST00000021993.4
Uqcrb
ubiquinol-cytochrome c reductase binding protein
chr6_+_123229843 0.368 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
Clec4n


C-type lectin domain family 4, member n


chr17_+_34604262 0.347 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr6_-_113377376 0.337 ENSMUST00000043333.2
Tada3
transcriptional adaptor 3
chr16_-_22857514 0.286 ENSMUST00000004576.6
Tbccd1
TBCC domain containing 1
chr11_-_6200411 0.273 ENSMUST00000066496.3
Nudcd3
NudC domain containing 3
chr4_+_155491353 0.263 ENSMUST00000165335.1
ENSMUST00000105616.3
ENSMUST00000030940.7
Gnb1


guanine nucleotide binding protein (G protein), beta 1


chr8_+_105860634 0.247 ENSMUST00000008594.7
Nutf2
nuclear transport factor 2
chr13_-_32781716 0.245 ENSMUST00000134352.1
ENSMUST00000057428.4
Mylk4

myosin light chain kinase family, member 4

chr15_-_35938186 0.241 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr13_-_97760588 0.228 ENSMUST00000074072.3
Gm10260
predicted gene 10260
chr3_+_98013503 0.227 ENSMUST00000079812.6
Notch2
notch 2
chr7_-_86775860 0.225 ENSMUST00000001824.5
Folh1
folate hydrolase 1
chr16_+_20498817 0.220 ENSMUST00000003320.6
Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr1_-_195131536 0.219 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr6_-_145048809 0.164 ENSMUST00000032402.5
Bcat1
branched chain aminotransferase 1, cytosolic
chr7_-_86775808 0.132 ENSMUST00000107271.3
Folh1
folate hydrolase 1
chr11_-_84870712 0.127 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr7_-_80901220 0.126 ENSMUST00000146402.1
ENSMUST00000026816.8
Wdr73

WD repeat domain 73

chr2_+_163602294 0.116 ENSMUST00000171696.1
ENSMUST00000109408.3
Ttpal

tocopherol (alpha) transfer protein-like

chr15_-_35938009 0.100 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr11_-_84870646 0.097 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr8_+_31150307 0.077 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr9_+_64179289 0.048 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr11_-_84870812 0.047 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr13_+_66905415 0.036 ENSMUST00000099412.2
Gm10767
predicted gene 10767
chr8_-_72475212 0.034 ENSMUST00000079510.4
Cherp
calcium homeostasis endoplasmic reticulum protein
chr15_+_103272893 0.034 ENSMUST00000100162.3
Copz1
coatomer protein complex, subunit zeta 1
chr3_-_36613285 0.008 ENSMUST00000108155.1
Bbs7
Bardet-Biedl syndrome 7 (human)
chr7_+_12897800 0.007 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
Zscan22



zinc finger and SCAN domain containing 22




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 1.6 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) regulation of peroxidase activity(GO:2000468)
0.3 2.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 0.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 1.8 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 0.9 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 2.6 GO:0099612 protein localization to axon(GO:0099612)
0.2 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.7 GO:0061744 motor behavior(GO:0061744)
0.2 0.6 GO:0006083 acetate metabolic process(GO:0006083)
0.2 3.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 0.8 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.2 0.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.5 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.2 0.6 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 11.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.2 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 1.2 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.5 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 1.2 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 2.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.4 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.0 1.0 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:1990769 proximal neuron projection(GO:1990769)
0.5 1.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 1.7 GO:0001533 cornified envelope(GO:0001533)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 3.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 3.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 12.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4 2.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 1.0 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 3.1 GO:0048406 neurotrophin TRKA receptor binding(GO:0005168) nerve growth factor binding(GO:0048406)
0.2 0.6 GO:0004875 complement receptor activity(GO:0004875)
0.2 3.0 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 0.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.3 GO:0031489 myosin V binding(GO:0031489)
0.1 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 11.4 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.7 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 2.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.3 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 3.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 1.8 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 2.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.1 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 3.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 2.0 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport