Motif ID: Pgr_Nr3c1

Z-value: 0.480

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39487096_394872450.438.5e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_20665250 8.722 ENSMUST00000075312.3
Ttr
transthyretin
chr13_-_84064772 4.151 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr10_+_97565436 1.891 ENSMUST00000038160.4
Lum
lumican
chr14_+_99298652 1.654 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr5_+_24364804 1.619 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr4_-_136898803 1.509 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr9_-_79718631 1.455 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr9_-_79718518 1.287 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr5_-_104114088 1.200 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr9_-_79718720 1.173 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr14_+_70555900 1.006 ENSMUST00000163060.1
Hr
hairless
chr11_+_111066154 0.959 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_-_152193803 0.878 ENSMUST00000050073.6
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_123140135 0.846 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr7_-_127824469 0.831 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr13_+_29016267 0.824 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr2_-_122611238 0.811 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_65620829 0.786 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr11_-_110168073 0.724 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_-_116473418 0.710 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr13_+_91461050 0.700 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr2_-_162661075 0.692 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr17_-_68004075 0.633 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr16_-_5222257 0.625 ENSMUST00000050160.4
AU021092
expressed sequence AU021092
chr10_+_100015817 0.594 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr5_+_125441546 0.585 ENSMUST00000049040.9
Bri3bp
Bri3 binding protein
chr6_+_17491216 0.581 ENSMUST00000080469.5
Met
met proto-oncogene
chr9_-_49798729 0.524 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr9_-_49798905 0.515 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr18_+_9707639 0.492 ENSMUST00000040069.8
Colec12
collectin sub-family member 12
chr14_-_16575456 0.484 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr14_+_123659971 0.466 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr5_+_65131184 0.454 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr7_-_78577771 0.449 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_142576492 0.419 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr14_-_124677089 0.415 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr2_-_154613425 0.413 ENSMUST00000181369.1
4930519P11Rik
RIKEN cDNA 4930519P11 gene
chr16_+_90831113 0.402 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr3_-_97868242 0.383 ENSMUST00000107038.3
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr13_+_75967704 0.382 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr11_-_83649349 0.367 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr17_-_25081138 0.360 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr2_-_63184253 0.357 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr7_-_109616548 0.343 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr16_+_43363855 0.322 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_+_93235836 0.304 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr4_-_53159885 0.298 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_-_12592556 0.294 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr19_+_55316313 0.286 ENSMUST00000095950.2
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chr12_+_103532435 0.286 ENSMUST00000021631.5
Ppp4r4
protein phosphatase 4, regulatory subunit 4
chr8_-_70234401 0.280 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr2_+_91256144 0.280 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr2_-_77170592 0.278 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr18_+_23415400 0.277 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr8_-_70042685 0.277 ENSMUST00000168013.2
ENSMUST00000050561.6
Mau2

MAU2 chromatid cohesion factor homolog (C. elegans)

chr15_+_82016420 0.255 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
Xrcc6


X-ray repair complementing defective repair in Chinese hamster cells 6


chr7_-_127725616 0.236 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr1_-_71653162 0.232 ENSMUST00000055226.6
Fn1
fibronectin 1
chr17_-_46031813 0.230 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr8_+_123373778 0.228 ENSMUST00000057934.3
ENSMUST00000108840.2
Tcf25

transcription factor 25 (basic helix-loop-helix)

chr4_+_136284708 0.225 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr4_+_136284658 0.221 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr3_+_106034661 0.219 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr11_+_105126425 0.214 ENSMUST00000021030.7
Mettl2
methyltransferase like 2
chr19_-_6084679 0.211 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr4_-_119422355 0.192 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr7_+_144838590 0.190 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr14_-_69732510 0.187 ENSMUST00000036381.8
Chmp7
charged multivesicular body protein 7
chr9_+_49102720 0.185 ENSMUST00000070390.5
ENSMUST00000167095.1
Tmprss5

transmembrane protease, serine 5 (spinesin)

chr17_+_8165501 0.182 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op

Fgfr1 oncogene partner

chr2_-_63184170 0.176 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr10_-_109010955 0.170 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr8_-_71043040 0.170 ENSMUST00000170101.1
Gm17576
predicted gene, 17576
chr2_+_163994960 0.168 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr8_+_70042768 0.159 ENSMUST00000011450.6
Sugp1
SURP and G patch domain containing 1
chr19_-_6084873 0.156 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr7_+_30712209 0.153 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr19_+_8741669 0.151 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
Stx5a


syntaxin 5A


chr7_+_49778334 0.147 ENSMUST00000140656.1
ENSMUST00000032715.6
Prmt3

protein arginine N-methyltransferase 3

chr4_-_120815703 0.140 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr10_+_14523062 0.138 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr13_-_106847267 0.136 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr15_-_89477400 0.136 ENSMUST00000165199.1
Arsa
arylsulfatase A
chr2_-_76673039 0.125 ENSMUST00000002809.7
Fkbp7
FK506 binding protein 7
chr11_+_87664274 0.121 ENSMUST00000092800.5
Rnf43
ring finger protein 43
chr7_+_30553263 0.111 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr17_-_6961156 0.111 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr11_-_48816936 0.105 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr12_-_4477138 0.105 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr10_+_102158858 0.104 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr8_-_105484350 0.099 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr16_-_91044473 0.098 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr12_-_86988676 0.092 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr2_-_65567465 0.090 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_+_39008076 0.090 ENSMUST00000112862.1
ENSMUST00000090993.5
Arpc5l

actin related protein 2/3 complex, subunit 5-like

chr2_-_65567505 0.088 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_30814571 0.086 ENSMUST00000031058.8
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr17_+_34644805 0.085 ENSMUST00000174796.1
Fkbpl
FK506 binding protein-like
chr2_+_91255954 0.082 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr3_-_120886691 0.080 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr5_+_30814722 0.078 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chrX_+_101383726 0.073 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr6_-_59024470 0.061 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr11_-_48817332 0.058 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr18_-_15063560 0.056 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr7_-_102477902 0.056 ENSMUST00000061482.5
Olfr543
olfactory receptor 543
chr12_-_24493656 0.055 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr9_+_46273064 0.055 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
Zfp259


zinc finger protein 259


chr10_-_83648631 0.053 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr6_-_59024340 0.051 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr15_+_81400132 0.049 ENSMUST00000163754.1
ENSMUST00000041609.4
Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr2_-_167043494 0.048 ENSMUST00000067584.6
Znfx1
zinc finger, NFX1-type containing 1
chr13_+_63015167 0.044 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr12_-_73047179 0.042 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr4_-_143299463 0.039 ENSMUST00000119654.1
Pdpn
podoplanin
chr11_+_31872100 0.031 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr8_+_46739745 0.010 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr5_-_24601961 0.010 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_+_76837408 0.003 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr3_+_121531603 0.003 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.6 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.5 1.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 1.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 0.8 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 1.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.8 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.6 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 1.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.6 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.4 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 0.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 1.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0001945 lymph vessel development(GO:0001945)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.2 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 1.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.8 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_FGF_PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 8.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 1.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.2 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade