Motif ID: Pou1f1
Z-value: 0.930
Transcription factors associated with Pou1f1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pou1f1 | ENSMUSG00000004842.12 | Pou1f1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou1f1 | mm10_v2_chr16_+_65520503_65520548 | -0.18 | 2.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.9 | 2.7 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 0.9 | 2.7 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
| 0.7 | 2.0 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.5 | 2.0 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.5 | 1.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
| 0.4 | 2.3 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 0.4 | 1.1 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 3.0 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.3 | 0.9 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
| 0.3 | 0.9 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.3 | 0.9 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.3 | 0.8 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.3 | 0.8 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 0.3 | 2.0 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
| 0.2 | 0.9 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.2 | 0.9 | GO:0032229 | negative regulation of synaptic transmission, GABAergic(GO:0032229) |
| 0.2 | 0.6 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.2 | 0.6 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.2 | 1.0 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
| 0.2 | 1.4 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.2 | 1.1 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.2 | 0.7 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
| 0.2 | 0.5 | GO:1904959 | regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
| 0.2 | 1.3 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.2 | 0.5 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.2 | 0.5 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.2 | 1.5 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.2 | 0.5 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 0.2 | 0.8 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.2 | 2.6 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.2 | 0.5 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.1 | 0.7 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 0.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 1.4 | GO:1902913 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 0.1 | 0.7 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.1 | 0.7 | GO:0031392 | regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) |
| 0.1 | 0.8 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 1.0 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 0.4 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
| 0.1 | 1.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.4 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 0.1 | 1.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.1 | 0.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.3 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
| 0.1 | 0.4 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
| 0.1 | 0.5 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.1 | 0.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 0.3 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 0.1 | 0.6 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 1.7 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.5 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.1 | 7.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 1.2 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.1 | 0.8 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.1 | 1.0 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.1 | 0.5 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.1 | 0.4 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.1 | 1.0 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.1 | 1.0 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 0.1 | 0.2 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.1 | 0.2 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
| 0.1 | 0.5 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.3 | GO:0001692 | histamine metabolic process(GO:0001692) positive regulation of gamma-aminobutyric acid secretion(GO:0014054) |
| 0.1 | 0.3 | GO:0072362 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.1 | 0.7 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.7 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.1 | 0.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 0.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 0.4 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
| 0.1 | 0.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.1 | 2.9 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.1 | 0.2 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.1 | 0.4 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.1 | 0.3 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.1 | 0.1 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.1 | 0.2 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.1 | 0.3 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.1 | 1.7 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 0.2 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.1 | 0.3 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 0.3 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.1 | 0.5 | GO:0006983 | ER overload response(GO:0006983) |
| 0.1 | 0.5 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.1 | 4.0 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
| 0.1 | 0.8 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.1 | 0.4 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 0.9 | GO:0000054 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) |
| 0.1 | 0.3 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
| 0.1 | 0.2 | GO:0021972 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.1 | 0.5 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
| 0.1 | 0.2 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) |
| 0.1 | 0.2 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
| 0.1 | 0.2 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 0.1 | 0.9 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.1 | 0.2 | GO:1904468 | negative regulation of tumor necrosis factor secretion(GO:1904468) |
| 0.1 | 1.1 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.1 | 0.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.1 | 0.8 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 0.4 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 0.8 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 0.2 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.1 | 0.3 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.1 | 0.6 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.6 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.0 | 0.6 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.0 | 0.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.0 | 1.8 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.3 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.4 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
| 0.0 | 0.3 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.1 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.0 | 0.5 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.5 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.0 | 1.5 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.0 | 0.3 | GO:0034351 | negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.2 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
| 0.0 | 0.4 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.0 | 1.0 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 0.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 5.8 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.0 | 0.6 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 1.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.0 | 0.7 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.0 | 0.2 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.0 | 0.7 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.0 | 0.2 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.0 | 0.1 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.0 | 0.3 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.7 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.1 | GO:0070859 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
| 0.0 | 1.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.4 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.0 | 0.3 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.0 | 0.3 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.0 | 0.3 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.2 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.0 | 0.2 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.0 | 0.2 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.0 | 0.1 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 0.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.0 | 0.1 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.0 | 0.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.0 | 0.3 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 1.0 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.4 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 0.2 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 0.0 | 0.0 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.0 | 0.3 | GO:0042711 | maternal behavior(GO:0042711) |
| 0.0 | 0.2 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.0 | 0.4 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 1.1 | GO:0061245 | establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245) |
| 0.0 | 0.1 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.0 | 0.4 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.4 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.0 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 0.0 | 0.5 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 0.3 | GO:0017144 | drug metabolic process(GO:0017144) |
| 0.0 | 0.0 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.8 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
| 0.0 | 1.2 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 1.3 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
| 0.0 | 0.1 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.0 | 0.3 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 0.5 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 0.1 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.0 | 0.2 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 0.2 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
| 0.0 | 0.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.1 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.0 | 0.1 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.0 | 0.1 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.0 | 0.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.0 | 0.1 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.0 | 0.8 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.3 | GO:0006366 | transcription from RNA polymerase II promoter(GO:0006366) |
| 0.0 | 0.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 0.9 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.4 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 1.5 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 0.0 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.0 | 0.0 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 1.0 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.0 | 0.2 | GO:0033194 | response to hydroperoxide(GO:0033194) |
| 0.0 | 0.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 1.8 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.4 | GO:0060021 | palate development(GO:0060021) |
| 0.0 | 0.4 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.0 | 0.2 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 0.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 1.3 | GO:0007051 | spindle organization(GO:0007051) |
| 0.0 | 0.7 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
| 0.0 | 0.1 | GO:0061525 | hindgut development(GO:0061525) |
| 0.0 | 0.1 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.0 | 0.1 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.0 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.0 | 0.1 | GO:0090043 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.3 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.2 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.1 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.0 | 0.1 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 0.2 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.0 | 0.1 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
| 0.0 | 0.1 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.0 | 0.6 | GO:0045454 | cell redox homeostasis(GO:0045454) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | GO:0071914 | prominosome(GO:0071914) |
| 0.8 | 6.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.5 | 2.6 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.4 | 1.1 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.3 | 2.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.3 | 1.4 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.2 | 0.7 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.2 | 2.3 | GO:0032009 | early phagosome(GO:0032009) |
| 0.2 | 1.1 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 1.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 0.6 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 0.9 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
| 0.1 | 1.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.4 | GO:1990047 | spindle matrix(GO:1990047) |
| 0.1 | 0.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.1 | 0.3 | GO:0031088 | platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.1 | 0.3 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.1 | 0.4 | GO:0030891 | VCB complex(GO:0030891) |
| 0.1 | 0.5 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.1 | 1.0 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 0.4 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.1 | 1.3 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 1.0 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 0.7 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.1 | 0.3 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 0.8 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 0.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 0.5 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 0.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 0.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 0.3 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.1 | 0.2 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.1 | 1.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 0.8 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 0.5 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 0.5 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.0 | 0.3 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.0 | 1.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.4 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.4 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.4 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 1.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 0.5 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 1.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 2.9 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 1.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.4 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.1 | GO:0000811 | GINS complex(GO:0000811) |
| 0.0 | 1.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.7 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.2 | GO:0044615 | nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 0.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.3 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.3 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.1 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 1.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.0 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.8 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.1 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 1.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 0.3 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.0 | 0.3 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 0.8 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.0 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 0.1 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.0 | 0.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.3 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.3 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 1.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 1.0 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 1.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.9 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 1.3 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.2 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 1.7 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.8 | 2.3 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
| 0.7 | 2.0 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.4 | 1.5 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
| 0.4 | 1.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.4 | 2.9 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.3 | 1.0 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
| 0.3 | 1.7 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.3 | 1.0 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.3 | 1.3 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.3 | 0.8 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.3 | 1.1 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.3 | 1.9 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.3 | 0.8 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.2 | 2.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.2 | 1.4 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.2 | 0.9 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.2 | 1.1 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 1.5 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.2 | 0.6 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.2 | 1.1 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.2 | 0.7 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
| 0.2 | 1.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 1.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.2 | 0.5 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 0.2 | 0.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.2 | 1.3 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.2 | 0.5 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 0.5 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.2 | 0.5 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
| 0.2 | 0.9 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 0.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 1.5 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.1 | 0.6 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 6.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.8 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.1 | 0.6 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.1 | 0.4 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 0.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.1 | 0.5 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.1 | 0.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.3 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.1 | 0.5 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 2.0 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.5 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.1 | 0.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.3 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.1 | 0.6 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 0.3 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.1 | 0.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.1 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.1 | 0.5 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 0.5 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 1.6 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.1 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 0.4 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 0.8 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.1 | 0.2 | GO:0001729 | ceramide kinase activity(GO:0001729) |
| 0.1 | 0.3 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 0.5 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 2.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 0.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 2.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.2 | GO:1990269 | RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269) |
| 0.1 | 1.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.6 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 0.2 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
| 0.1 | 0.3 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.0 | 0.1 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 0.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 1.1 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.0 | 0.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.0 | 2.3 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
| 0.0 | 0.4 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 0.4 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
| 0.0 | 0.4 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.0 | 0.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.0 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 0.0 | 0.2 | GO:0016508 | long-chain-enoyl-CoA hydratase activity(GO:0016508) |
| 0.0 | 0.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.0 | 0.1 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 0.2 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 1.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 1.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 1.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.2 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 0.7 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.0 | 0.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 0.1 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.0 | 1.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.2 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.2 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.0 | 0.5 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.0 | 0.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.2 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.0 | 0.1 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
| 0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.0 | 0.1 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.0 | 0.2 | GO:0048495 | GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495) |
| 0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 2.4 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.1 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.0 | 0.1 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.0 | 0.1 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 0.1 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.0 | 0.4 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 1.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.5 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.0 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.2 | GO:0070513 | death domain binding(GO:0070513) |
| 0.0 | 0.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.0 | 0.0 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 0.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.6 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.1 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.0 | 0.2 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 0.2 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.1 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.0 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.0 | 1.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.1 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.0 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.0 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.0 | 0.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 4.7 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 3.6 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 0.3 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 0.8 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 8.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.6 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 1.7 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 1.1 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.5 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 0.8 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 2.6 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 1.3 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 0.5 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.0 | 0.6 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.7 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.3 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.3 | PID_IL23_PATHWAY | IL23-mediated signaling events |
| 0.0 | 0.6 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.1 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.0 | 0.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 1.5 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 1.5 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 1.0 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.1 | 2.6 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 3.3 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 0.9 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.3 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 1.5 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 1.5 | REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Early Phase of HIV Life Cycle |
| 0.1 | 0.9 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 1.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 4.0 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 0.8 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 0.5 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 0.8 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 0.7 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 0.5 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | Genes involved in p53-Dependent G1 DNA Damage Response |
| 0.1 | 1.1 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 4.0 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.9 | REACTOME_PHASE_II_CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 0.5 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 1.3 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.3 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.6 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.0 | 1.9 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.4 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.6 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.9 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.7 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.8 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.3 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.3 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.2 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 1.6 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 0.5 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.2 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.0 | 0.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 3.2 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.2 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.4 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.7 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.3 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 0.4 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 1.1 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.0 | 0.2 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.2 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.3 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.2 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.1 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.2 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.3 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 1.0 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
