Motif ID: Pou2f2_Pou3f1

Z-value: 1.676

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.772.5e-08Click!
Pou2f2mm10_v2_chr7_-_25132473_25132512-0.221.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_67234620 24.811 ENSMUST00000176029.1
Ebf2
early B cell factor 2
chr6_-_67037399 22.422 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr6_+_8949670 14.222 ENSMUST00000060369.3
Nxph1
neurexophilin 1
chr13_-_56252163 13.430 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr2_+_103566304 11.982 ENSMUST00000076212.3
Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr14_+_13454010 11.883 ENSMUST00000112656.2
Synpr
synaptoporin
chr14_+_13453937 10.139 ENSMUST00000153954.1
Synpr
synaptoporin
chr1_+_6730051 9.866 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr19_+_20601958 9.079 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr7_+_45017953 8.979 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr8_+_45627709 8.874 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr12_+_38780284 8.769 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_172549581 8.539 ENSMUST00000030391.2
Tfap2c
transcription factor AP-2, gamma
chr12_+_38781093 8.243 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr12_+_38780817 8.119 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr9_+_74848437 7.587 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr8_-_90908415 7.402 ENSMUST00000098517.1
Gm6658
predicted gene 6658
chr1_+_6730135 7.150 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr8_+_108714644 6.831 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr2_+_105675478 6.646 ENSMUST00000167211.2
ENSMUST00000111083.3
Pax6

paired box gene 6

chr13_+_51846673 6.484 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr7_-_102100227 6.461 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr17_-_15375969 6.357 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr1_+_6487231 6.347 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr2_+_105675429 6.324 ENSMUST00000111085.1
Pax6
paired box gene 6
chr13_+_21722057 6.208 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr11_+_95337012 5.999 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr13_+_23684192 5.822 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr2_-_18048784 5.810 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr8_-_122678653 5.606 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr3_+_76074270 5.501 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr11_-_34833631 5.447 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr2_+_119047116 5.345 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr5_+_92897981 5.268 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr7_-_37769624 5.237 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr5_+_137630116 5.133 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr7_+_27486910 5.102 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr11_-_63922257 5.073 ENSMUST00000094103.3
Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr10_-_80421847 5.028 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_102099932 4.889 ENSMUST00000106934.1
Art5
ADP-ribosyltransferase 5
chr3_+_159495408 4.883 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a


DEP domain containing 1a


chr3_+_127633134 4.610 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr9_-_70421533 4.594 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr9_+_14276301 4.574 ENSMUST00000034507.7
Sesn3
sestrin 3
chr10_-_81350389 4.533 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chrX_-_23266751 4.519 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr13_-_22042949 4.273 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr9_-_22389113 4.266 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr13_+_23751069 4.263 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr2_+_119047129 4.244 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr14_-_67715585 4.195 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr2_-_64097994 4.178 ENSMUST00000131615.2
Fign
fidgetin
chr10_-_81350191 4.127 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr15_+_75862310 4.098 ENSMUST00000023238.4
Gsdmd
gasdermin D
chr7_-_144939823 4.088 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr4_+_97777606 4.020 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr11_+_34314757 3.952 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr13_-_21833575 3.909 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr10_-_81350305 3.873 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr3_+_96269695 3.793 ENSMUST00000051089.3
ENSMUST00000177113.1
Hist2h2bb

histone cluster 2, H2bb

chr13_-_23571151 3.762 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr2_-_26503814 3.754 ENSMUST00000028288.4
Notch1
notch 1
chr6_-_56369625 3.736 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c


phosphodiesterase 1C


chr6_+_30568367 3.677 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr12_-_34528844 3.633 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr17_+_27556613 3.620 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr3_-_101836223 3.552 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr17_+_27556668 3.534 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr3_-_96220880 3.526 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr6_-_3494587 3.420 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr13_+_23746734 3.400 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr13_+_23533869 3.363 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr17_+_27556641 3.349 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr14_-_48662740 3.265 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr13_+_22043189 3.257 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr4_+_128688726 3.234 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr2_+_160645881 3.153 ENSMUST00000109468.2
Top1
topoisomerase (DNA) I
chr12_+_89812467 3.079 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr2_+_25180737 3.058 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr2_-_30474199 3.045 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr4_-_110287479 2.971 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr3_-_96240317 2.963 ENSMUST00000078756.5
Hist2h2aa2
histone cluster 2, H2aa2
chr8_-_87959560 2.954 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr5_+_137629169 2.941 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_-_12345847 2.874 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr13_+_21833736 2.769 ENSMUST00000180288.1
ENSMUST00000110467.1
Hist1h2br

histone cluster 1 H2br

chr18_+_50051702 2.766 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr19_-_46045194 2.631 ENSMUST00000156585.1
ENSMUST00000152946.1
Ldb1

LIM domain binding 1

chr3_+_125404072 2.592 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_96245530 2.591 ENSMUST00000074976.6
Hist2h2aa1
histone cluster 2, H2aa1
chr1_-_89933290 2.564 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr4_+_128654686 2.545 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr5_+_53590215 2.514 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr13_+_23544052 2.510 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr1_+_109993982 2.493 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr13_+_23571382 2.487 ENSMUST00000079251.5
Hist1h2bg
histone cluster 1, H2bg
chr5_+_53590453 2.486 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr7_-_44997535 2.357 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr6_-_148946146 2.349 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr11_+_88294043 2.347 ENSMUST00000037268.4
1700106J16Rik
RIKEN cDNA 1700106J16 gene
chrX_+_56454871 2.339 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr3_+_125404292 2.278 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr19_-_6921753 2.220 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr19_-_40271506 2.180 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr19_-_46044914 2.165 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr13_+_21810428 2.097 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr13_+_22035821 2.074 ENSMUST00000110455.2
Hist1h2bk
histone cluster 1, H2bk
chr4_-_128806045 2.000 ENSMUST00000106072.2
ENSMUST00000170934.1
Zfp362

zinc finger protein 362

chr12_-_55014329 1.988 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr11_+_115824029 1.988 ENSMUST00000103032.4
ENSMUST00000133250.1
ENSMUST00000177736.1
Llgl2


lethal giant larvae homolog 2 (Drosophila)


chr19_+_47228804 1.978 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr1_-_52500679 1.976 ENSMUST00000069792.7
Nab1
Ngfi-A binding protein 1
chr7_-_143460989 1.885 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr4_+_97772734 1.884 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr9_+_75775355 1.786 ENSMUST00000012281.7
Bmp5
bone morphogenetic protein 5
chr2_+_155381808 1.750 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr7_-_109439076 1.704 ENSMUST00000106745.2
ENSMUST00000090414.4
Stk33

serine/threonine kinase 33

chr3_+_96219858 1.663 ENSMUST00000073115.4
Hist2h2ab
histone cluster 2, H2ab
chr8_-_115706994 1.651 ENSMUST00000069009.6
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr7_-_27166732 1.641 ENSMUST00000080058.4
Egln2
EGL nine homolog 2 (C. elegans)
chr7_+_24507006 1.635 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr5_+_146231211 1.609 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
Cdk8



cyclin-dependent kinase 8



chr6_-_65144908 1.592 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr19_-_6921804 1.587 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr14_+_62292475 1.546 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr5_-_5266038 1.546 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr7_+_29071597 1.529 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr11_-_77894096 1.526 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr1_-_14310198 1.483 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr13_-_23683941 1.466 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr14_+_67716262 1.464 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr1_+_52008210 1.461 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr4_-_130279205 1.450 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr7_-_37773555 1.437 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr6_+_88724828 1.422 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr14_+_67716095 1.420 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr10_+_128706251 1.403 ENSMUST00000054125.8
Pmel
premelanosome protein
chrX_+_109095359 1.364 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr1_+_91540553 1.344 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr2_-_152398046 1.330 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr17_-_58991343 1.286 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr5_-_74065736 1.259 ENSMUST00000145016.1
Usp46
ubiquitin specific peptidase 46
chr8_+_12395287 1.258 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr2_-_102451792 1.254 ENSMUST00000099678.3
Fjx1
four jointed box 1 (Drosophila)
chr2_+_27009926 1.246 ENSMUST00000114005.2
ENSMUST00000114004.1
ENSMUST00000114006.1
ENSMUST00000114007.1
Cacfd1



calcium channel flower domain containing 1



chr1_-_165934900 1.223 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr17_+_29490812 1.191 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr13_-_21787218 1.179 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr13_-_23621090 1.160 ENSMUST00000091704.5
ENSMUST00000051091.3
Hist1h2be

histone cluster 1, H2be

chr13_-_21810190 1.150 ENSMUST00000110469.1
ENSMUST00000091749.2
Hist1h2bq

histone cluster 1, H2bq

chr4_-_3938354 1.138 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr10_+_18469958 1.137 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr6_+_88724667 1.075 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr8_+_120488416 1.067 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr10_+_79927039 1.032 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a

AT rich interactive domain 3A (BRIGHT-like)

chr12_+_76404168 1.006 ENSMUST00000080449.5
Hspa2
heat shock protein 2
chr7_+_24507057 0.983 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr5_-_21701332 0.964 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr7_+_141195047 0.934 ENSMUST00000047093.4
Lrrc56
leucine rich repeat containing 56
chr10_-_13324160 0.928 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr1_+_75236439 0.917 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr19_+_5041337 0.913 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr13_+_21787461 0.903 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr7_+_24507122 0.890 ENSMUST00000177205.1
Zfp428
zinc finger protein 428
chr13_-_23934156 0.875 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr5_+_123015010 0.858 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr19_+_41593363 0.856 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr2_-_26092149 0.849 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr13_-_22035589 0.845 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr11_+_58948890 0.830 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr11_-_102185202 0.808 ENSMUST00000107156.2
Lsm12
LSM12 homolog (S. cerevisiae)
chr7_+_127746775 0.798 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr10_+_79927330 0.790 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr3_-_154328634 0.786 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chrX_+_150594420 0.773 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr17_+_47140942 0.759 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr1_-_192855723 0.751 ENSMUST00000155579.1
Sertad4
SERTA domain containing 4
chr1_-_163313661 0.743 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr2_-_168207063 0.723 ENSMUST00000088001.5
Adnp
activity-dependent neuroprotective protein
chr11_-_96829483 0.701 ENSMUST00000167149.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr2_+_155133501 0.697 ENSMUST00000029126.8
ENSMUST00000109685.1
Itch

itchy, E3 ubiquitin protein ligase

chr2_-_152830266 0.690 ENSMUST00000140436.1
Bcl2l1
BCL2-like 1
chr14_+_79515618 0.671 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr3_+_96221111 0.671 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chrX_-_111531163 0.669 ENSMUST00000128819.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr10_-_13324250 0.667 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr8_-_111393810 0.665 ENSMUST00000038475.8
Fa2h
fatty acid 2-hydroxylase
chr7_+_5015466 0.642 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr11_+_69838514 0.630 ENSMUST00000133967.1
ENSMUST00000094065.4
Tmem256

transmembrane protein 256

chr5_+_76656512 0.609 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr2_-_148045891 0.565 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr13_+_72628831 0.556 ENSMUST00000169028.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chrX_-_140543177 0.543 ENSMUST00000055738.5
Tsc22d3
TSC22 domain family, member 3
chr10_-_79908891 0.538 ENSMUST00000165684.1
ENSMUST00000164705.1
ENSMUST00000105378.2
ENSMUST00000170409.1
Med16



mediator complex subunit 16



chr2_-_152830615 0.537 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr5_+_135106881 0.531 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr2_-_160912292 0.531 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr2_-_157566319 0.507 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr12_-_115964196 0.492 ENSMUST00000103550.2
Ighv1-83
immunoglobulin heavy variable 1-83
chr11_+_115381906 0.476 ENSMUST00000053288.5
Cdr2l
cerebellar degeneration-related protein 2-like

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
3.4 13.4 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
2.8 8.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
2.6 13.0 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.3 25.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
2.3 6.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
2.2 28.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.9 23.4 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.9 3.8 GO:0061344 regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
1.5 24.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
1.4 4.3 GO:1904170 regulation of bleb assembly(GO:1904170)
1.3 2.6 GO:0021546 rhombomere development(GO:0021546)
1.2 4.8 GO:0043973 histone H3-K4 acetylation(GO:0043973)
1.1 9.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
1.0 12.6 GO:0002227 innate immune response in mucosa(GO:0002227)
1.0 4.1 GO:0070269 pyroptosis(GO:0070269)
0.9 1.8 GO:0021502 neural fold elevation formation(GO:0021502)
0.8 5.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.8 3.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.8 5.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.7 12.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.6 5.1 GO:0006477 protein sulfation(GO:0006477)
0.6 8.1 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 12.0 GO:0097237 cellular response to toxic substance(GO:0097237)
0.6 4.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.5 1.5 GO:0006553 lysine metabolic process(GO:0006553)
0.5 4.6 GO:0038203 TORC2 signaling(GO:0038203)
0.5 2.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 1.4 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.4 1.3 GO:0030539 male genitalia development(GO:0030539)
0.4 6.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 12.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 3.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.4 3.2 GO:0006265 DNA topological change(GO:0006265)
0.4 5.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 3.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.4 2.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.3 2.7 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.3 1.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 1.2 GO:0046898 response to cycloheximide(GO:0046898)
0.3 0.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 10.1 GO:0060074 synapse maturation(GO:0060074)
0.3 2.4 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.3 1.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 28.1 GO:0006342 chromatin silencing(GO:0006342)
0.2 1.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.0 GO:1903998 regulation of eating behavior(GO:1903998)
0.2 10.5 GO:0006284 base-excision repair(GO:0006284)
0.2 0.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 1.3 GO:0008343 adult feeding behavior(GO:0008343)
0.2 3.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.6 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 9.0 GO:0060325 face morphogenesis(GO:0060325)
0.2 7.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 1.6 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.2 4.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 0.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.5 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 1.0 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.1 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 5.1 GO:0043029 T cell homeostasis(GO:0043029)
0.1 11.5 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 4.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 2.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 5.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.2 GO:0070602 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 3.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 2.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 2.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.6 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 3.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 2.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.3 GO:0021510 spinal cord development(GO:0021510)
0.0 1.9 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.3 GO:0048469 cell maturation(GO:0048469)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
1.8 8.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.5 10.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.0 4.1 GO:0061702 inflammasome complex(GO:0061702)
0.9 22.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.9 4.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.8 3.2 GO:0001651 dense fibrillar component(GO:0001651)
0.5 2.0 GO:0008623 CHRAC(GO:0008623)
0.4 5.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 29.6 GO:0000786 nucleosome(GO:0000786)
0.4 4.6 GO:0061700 GATOR2 complex(GO:0061700)
0.3 1.0 GO:0036128 CatSper complex(GO:0036128)
0.3 1.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 1.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.3 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 4.5 GO:0035102 PRC1 complex(GO:0035102)
0.2 23.2 GO:0032993 protein-DNA complex(GO:0032993)
0.2 3.0 GO:0042788 polysomal ribosome(GO:0042788)
0.2 12.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 3.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 10.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 8.1 GO:0016605 PML body(GO:0016605)
0.1 4.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 28.1 GO:0000790 nuclear chromatin(GO:0000790)
0.1 4.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 23.9 GO:0016607 nuclear speck(GO:0016607)
0.1 4.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.1 6.9 GO:0043204 perikaryon(GO:0043204)
0.1 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 7.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.9 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 3.4 GO:0030496 midbody(GO:0030496)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 3.3 GO:0043296 apical junction complex(GO:0043296)
0.0 5.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0016234 inclusion body(GO:0016234)
0.0 0.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 2.0 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.5 23.5 GO:0003680 AT DNA binding(GO:0003680)
1.1 5.4 GO:0043515 kinetochore binding(GO:0043515)
0.8 5.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8 5.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.8 3.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.8 3.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.7 4.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6 4.1 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.5 3.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 4.8 GO:0030274 LIM domain binding(GO:0030274)
0.4 9.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.4 1.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.4 6.4 GO:0030957 Tat protein binding(GO:0030957)
0.4 1.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 16.3 GO:0070888 E-box binding(GO:0070888)
0.3 72.4 GO:0001047 core promoter binding(GO:0001047)
0.3 3.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 54.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 2.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.2 6.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 9.0 GO:0019003 GDP binding(GO:0019003)
0.1 1.2 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.6 GO:0019825 oxygen binding(GO:0019825)
0.1 1.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 2.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 7.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.4 GO:0002039 p53 binding(GO:0002039)
0.0 15.9 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 3.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 7.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 29.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.9 28.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.3 19.2 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 9.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 10.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.2 9.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 4.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 12.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 5.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 11.9 PID_CDC42_PATHWAY CDC42 signaling events
0.1 6.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.2 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 1.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 3.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 2.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 3.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
1.3 10.5 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.1 39.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.9 13.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6 9.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 6.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 9.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 5.0 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 4.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 4.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 9.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.9 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 5.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 8.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 3.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 5.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)