Motif ID: Pou5f1

Z-value: 0.909


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66831625 6.002 ENSMUST00000164163.1
 Sla
src-like adaptor
chr8_-_84773381 5.700 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_118283719 5.461 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr4_+_97772734 4.337 ENSMUST00000152023.1
 Nfia
nuclear factor I/A
chr6_-_138421379 4.197 ENSMUST00000163065.1
 Lmo3
LIM domain only 3
chr10_+_85386813 4.083 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr11_+_110399115 3.936 ENSMUST00000020949.5
ENSMUST00000100260.1
 Map2k6

mitogen-activated protein kinase kinase 6

chr14_-_12345847 3.761 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr10_-_64090241 3.596 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr5_+_66968559 3.524 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr5_+_129584169 3.508 ENSMUST00000031390.8
 Mmp17
matrix metallopeptidase 17
chr5_+_66968961 3.425 ENSMUST00000132991.1
 Limch1
LIM and calponin homology domains 1
chr10_-_64090265 3.350 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_+_136518820 3.148 ENSMUST00000032335.6
 Atf7ip
activating transcription factor 7 interacting protein
chr14_-_102982630 3.016 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr8_+_54954728 2.999 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr1_-_168431695 2.855 ENSMUST00000176790.1
 Pbx1
pre B cell leukemia homeobox 1
chr5_+_66968416 2.636 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr4_-_82705735 2.536 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr7_-_78578308 2.419 ENSMUST00000039431.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 7.8 GO:0031032 actomyosin structure organization(GO:0031032)
1.5 7.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.5 6.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 5.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 4.6 GO:0072189 ureter development(GO:0072189)
0.1 4.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 4.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 4.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 4.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.6 4.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.3 3.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.5 3.9 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.6 3.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 3.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.8 3.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.5 3.2 GO:0042756 drinking behavior(GO:0042756)
0.2 3.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.6 2.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 5.0 GO:0043196 varicosity(GO:0043196)
0.1 5.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 3.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.2 GO:0030175 filopodium(GO:0030175)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 2.0 GO:0042627 chylomicron(GO:0042627)
0.6 1.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 1.6 GO:0044308 axonal spine(GO:0044308)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.4 GO:0000805 X chromosome(GO:0000805)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.8 GO:0003779 actin binding(GO:0003779)
0.1 7.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 6.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 5.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
1.1 5.5 GO:0055100 adiponectin binding(GO:0055100)
0.6 4.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.3 4.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.3 3.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
1.1 3.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.3 2.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 2.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.7 2.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 2.0 GO:0030552 cAMP binding(GO:0030552)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 6.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 6.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.2 PID_ATR_PATHWAY ATR signaling pathway
0.2 3.9 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 3.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 2.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 2.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 2.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.4 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.9 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 3.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 2.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis