Motif ID: Pou5f1

Z-value: 0.909


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66831625 6.002 ENSMUST00000164163.1
Sla
src-like adaptor
chr8_-_84773381 5.700 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr8_+_118283719 5.461 ENSMUST00000117160.1
Cdh13
cadherin 13
chr4_+_97772734 4.337 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr6_-_138421379 4.197 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr10_+_85386813 4.083 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr11_+_110399115 3.936 ENSMUST00000020949.5
ENSMUST00000100260.1
Map2k6

mitogen-activated protein kinase kinase 6

chr14_-_12345847 3.761 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr10_-_64090241 3.596 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr5_+_66968559 3.524 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_+_129584169 3.508 ENSMUST00000031390.8
Mmp17
matrix metallopeptidase 17
chr5_+_66968961 3.425 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr10_-_64090265 3.350 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_+_136518820 3.148 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr14_-_102982630 3.016 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr8_+_54954728 2.999 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr1_-_168431695 2.855 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr5_+_66968416 2.636 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr4_-_82705735 2.536 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr7_-_78578308 2.419 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr14_-_39472825 2.415 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr19_-_41206774 2.387 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr1_-_168431502 2.293 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr11_+_98741871 2.284 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr1_-_25228814 2.259 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr3_+_67892189 2.193 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr6_+_88724667 2.115 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr18_-_42899294 2.092 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899470 2.087 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr6_-_55681257 2.008 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr8_+_68880491 1.998 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr1_-_154725920 1.890 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr6_+_88724828 1.883 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr6_+_108213086 1.867 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr7_+_91090697 1.865 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr7_+_91090728 1.827 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr1_-_126830786 1.819 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr4_+_102254993 1.813 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_92481343 1.803 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr2_+_124610573 1.787 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr4_+_123183722 1.749 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr14_-_79771305 1.740 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr7_+_87803815 1.663 ENSMUST00000125009.1
ENSMUST00000155358.1
Grm5

glutamate receptor, metabotropic 5

chr1_-_126830632 1.660 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr11_+_98741805 1.586 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr1_-_168431896 1.539 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr6_-_13839916 1.507 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr11_+_58954675 1.501 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr16_+_91729281 1.494 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr18_-_43393346 1.480 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_+_95337012 1.467 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr13_+_16014457 1.439 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr16_-_4559720 1.397 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr13_+_42680565 1.387 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chrX_-_103483205 1.386 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr1_-_168432270 1.374 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr10_-_127620960 1.357 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr2_+_55437100 1.355 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr10_-_127620922 1.352 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr18_-_80151467 1.343 ENSMUST00000066743.9
Adnp2
ADNP homeobox 2
chr6_-_30693676 1.326 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr13_-_41358990 1.296 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr15_-_100599864 1.293 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr4_+_152039315 1.284 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr6_-_99266494 1.282 ENSMUST00000113326.2
Foxp1
forkhead box P1
chrX_-_165327376 1.264 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr2_-_6722187 1.233 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr1_+_177444653 1.206 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr6_-_136171722 1.205 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr13_+_97241096 1.203 ENSMUST00000041623.7
Enc1
ectodermal-neural cortex 1
chrX_+_93675088 1.173 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr10_+_39612934 1.173 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr16_+_23224724 1.171 ENSMUST00000023601.7
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr6_+_92092369 1.148 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr13_+_40917626 1.066 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr17_-_28486082 1.052 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr11_-_30198232 1.046 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr5_+_105732063 1.032 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr2_-_45117349 1.012 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_95444789 1.004 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr13_-_56252163 1.004 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr7_+_24507099 0.993 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr10_+_118860826 0.988 ENSMUST00000059966.4
4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr13_+_40886758 0.984 ENSMUST00000069958.7
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_+_47530173 0.975 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr12_+_29528382 0.975 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr9_+_35423582 0.956 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr18_-_74961252 0.946 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr2_-_6721890 0.942 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr16_-_22439570 0.926 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr17_-_35164891 0.912 ENSMUST00000025253.5
Prrc2a
proline-rich coiled-coil 2A
chr7_+_24507006 0.904 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr11_-_98775333 0.904 ENSMUST00000064941.6
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr5_+_105731755 0.892 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr5_+_111417263 0.871 ENSMUST00000094463.4
Mn1
meningioma 1
chr1_+_34579693 0.867 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr11_-_69605829 0.854 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr11_+_57011798 0.851 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr2_-_120539852 0.845 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr19_+_26750939 0.845 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_124677089 0.835 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr9_-_102354685 0.816 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr5_-_142895233 0.803 ENSMUST00000035985.7
Fbxl18
F-box and leucine-rich repeat protein 18
chr3_+_96221111 0.798 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr9_+_44773191 0.795 ENSMUST00000147559.1
Ift46
intraflagellar transport 46
chr9_+_86743616 0.791 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr11_+_57011945 0.783 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr5_+_123015010 0.782 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr13_-_23683941 0.777 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr5_-_122988533 0.770 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr8_+_120488416 0.763 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr18_+_65582239 0.762 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chr5_-_122989086 0.725 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr18_+_65582281 0.707 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr1_+_153652943 0.693 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr9_+_86743641 0.676 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr3_+_13946368 0.673 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr4_+_123183456 0.669 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr13_-_115090123 0.665 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr2_+_25180737 0.661 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr3_+_45378396 0.645 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chr17_-_46556158 0.639 ENSMUST00000015749.5
Srf
serum response factor
chr8_-_70234097 0.626 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr2_+_57238297 0.624 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr11_-_119086221 0.623 ENSMUST00000026665.7
Cbx4
chromobox 4
chr13_-_28953690 0.621 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr10_-_127621107 0.618 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chr11_-_84068766 0.616 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr10_+_18469958 0.615 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr8_-_33747724 0.612 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr16_-_17144415 0.608 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr5_-_74065736 0.607 ENSMUST00000145016.1
Usp46
ubiquitin specific peptidase 46
chr2_-_66440753 0.601 ENSMUST00000112371.2
ENSMUST00000138910.1
Scn1a

sodium channel, voltage-gated, type I, alpha

chr1_+_91540553 0.599 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr13_+_23684192 0.598 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr7_+_24507057 0.591 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr2_+_155382186 0.586 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr1_+_143640664 0.586 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_152398046 0.582 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr11_-_84069179 0.580 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr7_+_5015466 0.579 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chrX_+_94234594 0.577 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr3_-_50443603 0.573 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr1_-_91459254 0.567 ENSMUST00000069620.8
Per2
period circadian clock 2
chr19_+_8941865 0.567 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr11_+_108920800 0.561 ENSMUST00000140821.1
Axin2
axin2
chr18_-_37969742 0.559 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr4_-_14621669 0.558 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621805 0.548 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_-_76215363 0.546 ENSMUST00000144892.1
Pde11a
phosphodiesterase 11A
chr7_-_28372597 0.532 ENSMUST00000144700.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr13_-_54688264 0.529 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr13_-_83729544 0.529 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr13_-_54688246 0.518 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr15_-_100599983 0.514 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr18_+_69593361 0.508 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr15_+_82147238 0.504 ENSMUST00000023100.6
Srebf2
sterol regulatory element binding factor 2
chr13_-_23574196 0.503 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr11_+_103103051 0.498 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr1_+_66386968 0.498 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr8_-_70234401 0.481 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr8_-_89147247 0.480 ENSMUST00000177870.1
Gm6625
predicted gene 6625
chr13_+_23934434 0.479 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr12_-_86988676 0.477 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr3_-_80802789 0.476 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr1_+_36471590 0.469 ENSMUST00000153128.1
Cnnm4
cyclin M4
chr2_-_71367749 0.464 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr10_+_97479470 0.464 ENSMUST00000105287.3
Dcn
decorin
chr16_-_91728701 0.459 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr11_-_100527862 0.454 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr18_-_79109391 0.453 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr6_-_29216277 0.448 ENSMUST00000162215.1
Impdh1
inosine 5'-phosphate dehydrogenase 1
chr3_-_96220880 0.448 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr1_-_64121389 0.443 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr12_-_79192248 0.443 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr13_+_5861489 0.439 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr8_+_70234613 0.434 ENSMUST00000145078.1
Sugp2
SURP and G patch domain containing 2
chr13_+_23574381 0.434 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr5_-_148928619 0.433 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr18_+_65582390 0.430 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr11_-_84067063 0.429 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr2_+_143546144 0.412 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr9_+_14276301 0.409 ENSMUST00000034507.7
Sesn3
sestrin 3
chr2_-_180273488 0.409 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr4_-_14621494 0.405 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr19_-_6921804 0.401 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr15_+_12824815 0.399 ENSMUST00000169061.1
Drosha
drosha, ribonuclease type III
chr14_+_17660956 0.395 ENSMUST00000022303.7
ENSMUST00000091471.4
Thrb

thyroid hormone receptor beta

chr3_-_58885212 0.383 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
Clrn1


clarin 1


chr4_-_62360524 0.383 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr7_+_107370728 0.376 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr7_-_102100227 0.372 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr7_+_82175156 0.371 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr15_+_12824841 0.370 ENSMUST00000090292.5
Drosha
drosha, ribonuclease type III
chr17_+_28142267 0.367 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr16_+_17144600 0.366 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr6_-_148946146 0.366 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr2_-_33087169 0.366 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr6_-_30304513 0.362 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr19_-_6921753 0.360 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.3 3.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.8 3.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.8 2.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.8 2.4 GO:0060596 mammary placode formation(GO:0060596)
0.6 2.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 3.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 1.8 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.6 4.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 1.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.5 3.9 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.5 6.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.5 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.5 3.2 GO:0042756 drinking behavior(GO:0042756)
0.4 1.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 1.9 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 2.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.3 1.0 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 4.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3 0.6 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.3 0.9 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.3 1.9 GO:0042045 epithelial fluid transport(GO:0042045)
0.3 0.9 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.3 1.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) negative regulation of dendritic spine maintenance(GO:1902951)
0.3 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 1.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 1.2 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.3 1.5 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 4.6 GO:0072189 ureter development(GO:0072189)
0.3 1.4 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 3.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.3 8.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 1.5 GO:0019532 oxalate transport(GO:0019532)
0.3 1.0 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
0.2 3.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 1.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.2 1.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012) cellular response to zinc ion(GO:0071294)
0.2 0.6 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.2 1.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.6 GO:0010958 regulation of amino acid import(GO:0010958) regulation of DNA-templated transcription, termination(GO:0031554)
0.2 0.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 1.0 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 1.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0021678 third ventricle development(GO:0021678)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 2.0 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.3 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886) negative regulation of cholesterol efflux(GO:0090370)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 4.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 1.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 5.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.1 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.2 GO:0061054 dermatome development(GO:0061054) sclerotome development(GO:0061056) regulation of dermatome development(GO:0061183)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 4.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 4.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929) positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 2.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 2.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 7.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.2 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.9 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.9 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.3 5.0 GO:0043196 varicosity(GO:0043196)
0.3 2.0 GO:0042627 chylomicron(GO:0042627)
0.3 1.6 GO:0044308 axonal spine(GO:0044308)
0.3 0.8 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 2.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.0 GO:0032437 cuticular plate(GO:0032437)
0.2 3.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.4 GO:0000805 X chromosome(GO:0000805)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 6.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 6.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 3.2 GO:0030175 filopodium(GO:0030175)
0.0 9.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 4.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.1 3.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.1 5.5 GO:0055100 adiponectin binding(GO:0055100)
0.7 2.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.6 4.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.5 2.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 1.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 4.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 2.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.6 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 3.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 6.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 1.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.8 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.0 GO:0050897 cobalt ion binding(GO:0050897)
0.1 2.0 GO:0030552 cAMP binding(GO:0030552)
0.1 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 7.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 5.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:1990188 euchromatin binding(GO:1990188)
0.0 2.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 9.8 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 2.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.2 2.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 4.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 5.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 8.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 4.2 PID_ATR_PATHWAY ATR signaling pathway
0.1 1.8 PID_SHP2_PATHWAY SHP2 signaling
0.0 6.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 1.4 PID_ALK1_PATHWAY ALK1 signaling events
0.0 6.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 3.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 7.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.9 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 4.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.8 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.3 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.2 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 2.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 2.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling