Motif ID: Ppara

Z-value: 1.717


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_61523889 14.092 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr15_-_66801577 9.884 ENSMUST00000168589.1
Sla
src-like adaptor
chr6_-_138422898 9.569 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr15_-_45114926 8.808 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chrX_-_72656135 7.817 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr8_+_118283719 7.652 ENSMUST00000117160.1
Cdh13
cadherin 13
chr11_+_67586675 7.500 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr5_-_44799643 7.360 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr13_-_9878998 7.268 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr11_+_67586520 7.044 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr10_-_64090265 6.893 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_-_74554474 6.632 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr2_-_13011747 6.171 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr3_-_36690118 5.915 ENSMUST00000029271.4
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr11_+_7063423 5.873 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr12_+_109545390 5.800 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr10_-_64090241 5.724 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_-_25005895 5.712 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr11_-_33147400 5.700 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr4_+_13751297 5.584 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_57314896 5.550 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr1_+_32172711 5.487 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr4_+_123183722 5.399 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr6_-_99028874 5.255 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr6_+_96115249 5.200 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr1_-_84696182 5.193 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr10_-_33995054 5.118 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr10_+_123264076 4.891 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr17_+_28142267 4.879 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr11_-_75796048 4.804 ENSMUST00000021209.7
Doc2b
double C2, beta
chr11_+_42419729 4.771 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr14_-_23803304 4.723 ENSMUST00000179836.1
ENSMUST00000172099.2
ENSMUST00000065788.8
ENSMUST00000179097.1
ENSMUST00000177634.1
ENSMUST00000074983.6
ENSMUST00000163322.2
ENSMUST00000100831.4
Kcnma1







potassium large conductance calcium-activated channel, subfamily M, alpha member 1







chr12_-_67221221 4.662 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr5_+_150259922 4.652 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr8_+_124793061 4.631 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr1_-_162478004 4.556 ENSMUST00000086074.5
ENSMUST00000070330.7
Dnm3

dynamin 3

chr7_-_74554726 4.539 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr17_-_35909626 4.386 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chrX_-_52165252 4.342 ENSMUST00000033450.2
Gpc4
glypican 4
chr7_-_98162318 4.274 ENSMUST00000107112.1
Capn5
calpain 5
chr8_+_124793013 4.184 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr11_+_97450136 4.140 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr18_+_77185815 4.109 ENSMUST00000079618.4
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr5_-_66514815 4.094 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr17_-_35910032 4.068 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr2_+_121295437 4.053 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr8_+_36457548 4.043 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr15_-_79804717 3.995 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr6_-_99028251 3.963 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr4_-_134254076 3.818 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr10_-_89257790 3.732 ENSMUST00000045601.7
Ano4
anoctamin 4
chr3_-_158562199 3.619 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr10_-_119240006 3.547 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr11_-_74590065 3.538 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr15_+_30172570 3.471 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr2_+_71981184 3.408 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr14_+_58070547 3.390 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr16_-_4523056 3.378 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr3_+_68572245 3.325 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr19_+_43440404 3.289 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr15_+_92161343 3.281 ENSMUST00000068378.5
Cntn1
contactin 1
chr1_+_75375271 3.273 ENSMUST00000087122.5
Speg
SPEG complex locus
chr2_+_166805506 3.268 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr6_+_91157373 3.260 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr1_+_134193432 3.171 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr11_-_3504766 3.069 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr7_+_91090728 3.068 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr1_-_13374072 3.068 ENSMUST00000068304.6
ENSMUST00000006037.6
Ncoa2

nuclear receptor coactivator 2

chr10_-_125328957 3.067 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr14_-_30607808 3.046 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr1_-_183147461 3.005 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr9_-_106656081 2.988 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr1_-_136260873 2.975 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr15_+_100761741 2.947 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr10_-_89257578 2.906 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chr2_-_80128834 2.889 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_+_72054598 2.846 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_+_87026564 2.830 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr12_+_109544498 2.828 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr2_+_178118975 2.817 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3
chr7_+_43797567 2.805 ENSMUST00000085461.2
Klk8
kallikrein related-peptidase 8
chr2_-_5676046 2.778 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr6_-_142964404 2.771 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr2_+_178119166 2.769 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr13_-_102958084 2.743 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr2_-_112480817 2.733 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr9_-_77251829 2.726 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr2_-_80129458 2.714 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr19_+_57611020 2.704 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr15_-_44428303 2.668 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr6_-_124768330 2.653 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr5_-_5265224 2.626 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr1_-_3671498 2.600 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr17_+_28575718 2.599 ENSMUST00000080780.6
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr1_+_159737510 2.587 ENSMUST00000111669.3
Tnr
tenascin R
chr1_-_183221529 2.577 ENSMUST00000003035.5
Disp1
dispatched homolog 1 (Drosophila)
chr6_-_91473361 2.563 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr15_+_84669565 2.560 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr17_-_83631892 2.549 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr12_-_111672290 2.536 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr3_+_103575231 2.525 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr2_+_170731807 2.515 ENSMUST00000029075.4
Dok5
docking protein 5
chr11_-_37235882 2.513 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr1_+_133309778 2.511 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr6_-_59024340 2.506 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr5_+_66968559 2.489 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr1_-_134235420 2.486 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr2_-_7396192 2.475 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr6_-_59024470 2.472 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr1_+_131910458 2.462 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_+_50110837 2.458 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr7_+_121707189 2.445 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr4_+_54945038 2.444 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr1_+_75400070 2.444 ENSMUST00000113589.1
Speg
SPEG complex locus
chr3_+_103575275 2.414 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr11_+_70023905 2.401 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chr3_+_153973436 2.339 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr17_-_91088726 2.327 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr4_+_123183456 2.313 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr2_-_7395879 2.294 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr5_-_24995748 2.289 ENSMUST00000076306.5
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_+_38264761 2.288 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr9_-_77251871 2.272 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr13_-_91388079 2.265 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr4_-_141599835 2.264 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr2_+_164805082 2.247 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chrX_-_136203637 2.235 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr17_+_5492558 2.201 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr4_-_117125618 2.181 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr11_+_98741805 2.178 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr14_-_74947865 2.172 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_+_178141920 2.166 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr6_+_22875496 2.162 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr10_-_81025521 2.161 ENSMUST00000144640.1
Diras1
DIRAS family, GTP-binding RAS-like 1
chr16_-_44139630 2.157 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr4_+_63558748 2.144 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr18_+_59175333 2.140 ENSMUST00000080721.4
Chsy3
chondroitin sulfate synthase 3
chr1_+_127204986 2.138 ENSMUST00000038361.4
Mgat5
mannoside acetylglucosaminyltransferase 5
chr6_+_91156665 2.129 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr12_+_117516479 2.125 ENSMUST00000109691.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr7_-_98309471 2.120 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr11_-_42000532 2.110 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr8_-_123894736 2.094 ENSMUST00000034453.4
Acta1
actin, alpha 1, skeletal muscle
chr17_+_91088493 2.088 ENSMUST00000095183.1
Gm10308
predicted gene 10308
chr6_+_91156772 2.087 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr15_-_79505241 2.061 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr12_+_86678685 2.058 ENSMUST00000021681.3
Vash1
vasohibin 1
chr2_-_54085542 2.046 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_-_127409014 2.041 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr9_-_70141484 2.036 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr16_-_34095983 2.018 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr3_-_127408937 2.017 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr6_-_28830345 2.015 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr11_-_74590186 2.007 ENSMUST00000102521.1
Rap1gap2
RAP1 GTPase activating protein 2
chr1_-_87573825 1.984 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr2_-_33428222 1.977 ENSMUST00000091037.2
Zbtb34
zinc finger and BTB domain containing 34
chr12_-_17176888 1.977 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr3_+_96830069 1.976 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr15_+_23036449 1.968 ENSMUST00000164787.1
Cdh18
cadherin 18
chr4_-_119492563 1.963 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr10_-_109764840 1.952 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr5_+_111581422 1.940 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr15_+_73723131 1.935 ENSMUST00000165541.1
ENSMUST00000167582.1
Ptp4a3

protein tyrosine phosphatase 4a3

chr11_-_98775333 1.934 ENSMUST00000064941.6
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr1_+_90203980 1.931 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr15_+_7129557 1.913 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr17_+_27655572 1.901 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr16_-_16869255 1.892 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr4_-_137048695 1.883 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr4_-_36136463 1.870 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr19_-_37207293 1.851 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr18_+_77185979 1.845 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_-_81706905 1.836 ENSMUST00000026922.7
Homer2
homer homolog 2 (Drosophila)
chr11_-_76577701 1.829 ENSMUST00000176179.1
Abr
active BCR-related gene
chr1_-_52499980 1.826 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr17_+_83706170 1.824 ENSMUST00000067826.8
Mta3
metastasis associated 3
chr6_-_85502858 1.821 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr6_+_113697050 1.815 ENSMUST00000089018.4
Tatdn2
TatD DNase domain containing 2
chr1_+_36068371 1.814 ENSMUST00000088174.3
Hs6st1
heparan sulfate 6-O-sulfotransferase 1
chr3_-_127408986 1.801 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr5_+_137761680 1.780 ENSMUST00000110983.2
ENSMUST00000031738.4
Tsc22d4

TSC22 domain family, member 4

chr15_+_78430086 1.775 ENSMUST00000162808.1
Kctd17
potassium channel tetramerisation domain containing 17
chr18_+_63708689 1.770 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr17_+_83706137 1.768 ENSMUST00000112350.1
ENSMUST00000112349.2
ENSMUST00000112352.3
Mta3


metastasis associated 3


chr3_-_127409044 1.764 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr19_-_47015113 1.736 ENSMUST00000172239.2
Nt5c2
5'-nucleotidase, cytosolic II
chr10_-_78464853 1.735 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr10_+_128083273 1.732 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr15_+_61987410 1.729 ENSMUST00000160009.1
Myc
myelocytomatosis oncogene
chrX_+_86191764 1.719 ENSMUST00000026036.4
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr1_-_167393826 1.708 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr9_-_21037775 1.697 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr11_-_95699143 1.693 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr14_+_32321987 1.685 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr3_-_107517321 1.680 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr5_+_130144861 1.677 ENSMUST00000040616.2
Kctd7
potassium channel tetramerisation domain containing 7
chr2_-_7081207 1.676 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr7_-_4445595 1.675 ENSMUST00000119485.1
Rdh13
retinol dehydrogenase 13 (all-trans and 9-cis)
chr13_+_31558157 1.660 ENSMUST00000042118.8
Foxq1
forkhead box Q1
chr1_+_72824482 1.649 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0071929 alpha-tubulin acetylation(GO:0071929)
2.2 6.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
2.0 10.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.0 5.9 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.6 4.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.6 4.7 GO:1904347 intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
1.6 6.3 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
1.5 7.7 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
1.5 4.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
1.4 5.7 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.1 4.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
1.0 9.3 GO:0071420 cellular response to histamine(GO:0071420)
1.0 9.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.0 2.9 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.9 2.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.9 9.2 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.9 2.8 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.9 5.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.9 2.6 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.8 12.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.8 2.5 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.8 2.5 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.8 1.6 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.8 11.2 GO:0015732 prostaglandin transport(GO:0015732)
0.8 3.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.8 3.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.7 2.2 GO:2000331 regulation of terminal button organization(GO:2000331)
0.7 2.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.7 3.4 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.7 2.6 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.6 1.9 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.6 1.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 3.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.6 3.7 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.6 2.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.5 1.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.5 1.6 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.5 1.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.5 4.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.5 2.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.5 5.6 GO:0060539 diaphragm development(GO:0060539)
0.5 2.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.5 1.5 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.5 2.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 1.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 1.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 8.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.4 1.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 6.1 GO:0030238 male sex determination(GO:0030238)
0.4 8.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 3.9 GO:0009644 response to high light intensity(GO:0009644)
0.4 1.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.4 1.7 GO:0044330 pyruvate transport(GO:0006848) canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.4 0.4 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.4 5.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.4 2.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.4 7.3 GO:0010669 epithelial structure maintenance(GO:0010669)
0.4 2.8 GO:0090234 cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234)
0.4 2.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 4.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 1.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 1.1 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.4 1.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 4.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 1.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.4 1.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4 2.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 5.2 GO:0007220 Notch receptor processing(GO:0007220)
0.3 1.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.3 1.0 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 1.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 1.7 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 1.0 GO:0060003 copper ion export(GO:0060003)
0.3 1.0 GO:0018343 protein farnesylation(GO:0018343)
0.3 2.0 GO:0015879 carnitine transport(GO:0015879)
0.3 1.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.3 8.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 1.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 1.0 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.3 1.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 2.5 GO:0097264 self proteolysis(GO:0097264)
0.3 0.6 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3 0.9 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 8.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 1.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 4.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 2.6 GO:0038203 TORC2 signaling(GO:0038203)
0.3 2.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 3.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 2.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3 1.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.3 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.3 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.3 1.0 GO:0046103 inosine biosynthetic process(GO:0046103)
0.3 0.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.3 0.3 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612)
0.3 1.0 GO:0035826 rubidium ion transport(GO:0035826)
0.2 1.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 0.7 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.4 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 0.9 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.2 9.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 1.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 3.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 0.4 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.2 1.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.9 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 1.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 2.1 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.2 3.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.2 8.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 2.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 1.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 1.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.2 1.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.6 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 1.1 GO:1903056 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 4.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.7 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 1.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 2.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 2.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 1.3 GO:0019388 galactose catabolic process(GO:0019388)
0.2 3.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 1.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 1.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.9 GO:0051665 membrane raft localization(GO:0051665)
0.2 3.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 2.9 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 3.1 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 2.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 2.0 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 0.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.6 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 5.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 6.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 0.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 1.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 3.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.6 GO:0021548 pons development(GO:0021548)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 2.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 5.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 2.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.8 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.1 2.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.7 GO:0060013 righting reflex(GO:0060013)
0.1 0.7 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.3 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.9 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 0.4 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.1 1.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.4 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 4.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.8 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.6 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.1 5.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.1 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:0060261 positive regulation of isotype switching to IgG isotypes(GO:0048304) positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.1 0.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 3.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 4.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.1 0.9 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 2.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 12.3 GO:0030041 actin filament polymerization(GO:0030041)
0.1 2.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.7 GO:1902255 fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 1.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.5 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 7.6 GO:0050807 regulation of synapse organization(GO:0050807)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.6 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.1 0.8 GO:0015809 arginine transport(GO:0015809)
0.1 1.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.8 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.9 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0002922 positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847)
0.1 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.1 0.5 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.6 GO:0000022 mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.1 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 2.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.7 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 3.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.8 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.0 0.7 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.6 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 4.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.6 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.4 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111) negative regulation of microtubule polymerization(GO:0031115)
0.0 1.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0033572 transferrin transport(GO:0033572)
0.0 8.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.6 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.7 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.0 1.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 5.5 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.3 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0030538 hindgut morphogenesis(GO:0007442) embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.0 2.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.2 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.3 GO:0007286 spermatid development(GO:0007286)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.7 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of lymphocyte proliferation(GO:0050670)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0000423 macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0072534 perineuronal net(GO:0072534)
1.3 6.3 GO:0044316 cone cell pedicle(GO:0044316)
1.1 17.1 GO:1902711 GABA-A receptor complex(GO:1902711)
1.1 4.6 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.8 3.3 GO:0032280 symmetric synapse(GO:0032280)
0.7 6.2 GO:0097427 microtubule bundle(GO:0097427)
0.6 6.0 GO:0044326 dendritic spine neck(GO:0044326)
0.6 1.2 GO:0097444 spine apparatus(GO:0097444)
0.6 1.7 GO:1990075 periciliary membrane compartment(GO:1990075)
0.6 6.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 3.2 GO:0005859 muscle myosin complex(GO:0005859)
0.5 2.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 9.3 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.4 4.4 GO:0032426 stereocilium tip(GO:0032426)
0.4 1.3 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.4 2.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 2.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 2.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 1.3 GO:1902636 kinociliary basal body(GO:1902636)
0.3 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 0.6 GO:0016939 kinesin II complex(GO:0016939)
0.3 5.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 5.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 4.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 0.5 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 1.2 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 6.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 2.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 1.0 GO:0032437 cuticular plate(GO:0032437)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.7 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 4.1 GO:0031430 M band(GO:0031430)
0.2 2.2 GO:0005687 U4 snRNP(GO:0005687)
0.2 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 0.7 GO:0005745 m-AAA complex(GO:0005745)
0.2 0.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 2.6 GO:0031932 TORC2 complex(GO:0031932)
0.2 2.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 1.2 GO:0097413 Lewy body(GO:0097413)
0.2 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.7 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.7 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.0 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0001651 dense fibrillar component(GO:0001651)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 3.2 GO:0099738 cell cortex region(GO:0099738)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 7.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 3.6 GO:0043194 axon initial segment(GO:0043194)
0.1 15.4 GO:0005884 actin filament(GO:0005884)
0.1 8.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 12.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 11.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.8 GO:0071598 commitment complex(GO:0000243) neuronal ribonucleoprotein granule(GO:0071598) U2AF(GO:0089701)
0.1 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 7.5 GO:0005604 basement membrane(GO:0005604)
0.1 7.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.5 GO:0031201 SNARE complex(GO:0031201)
0.1 3.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.2 GO:0051233 spindle midzone(GO:0051233)
0.1 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 16.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 3.1 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 6.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 1.3 GO:0097440 apical dendrite(GO:0097440)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.8 GO:0000776 kinetochore(GO:0000776)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 17.3 GO:0009986 cell surface(GO:0009986)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.8 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 14.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 2.0 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.9 GO:0044297 cell body(GO:0044297)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.9 GO:0043679 axon terminus(GO:0043679)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 3.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.7 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.9 5.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.6 11.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.6 4.8 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.6 4.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.5 7.7 GO:0055100 adiponectin binding(GO:0055100)
1.5 4.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.5 8.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.4 8.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.0 3.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.0 4.0 GO:0001847 opsonin receptor activity(GO:0001847)
1.0 5.9 GO:0033142 progesterone receptor binding(GO:0033142)
0.9 2.8 GO:0031403 lithium ion binding(GO:0031403)
0.9 5.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.8 5.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.8 5.6 GO:0015197 peptide transporter activity(GO:0015197)
0.8 3.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.8 3.0 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.7 12.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 2.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.7 2.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 4.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 2.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.6 1.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 1.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.6 3.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 2.5 GO:0004111 creatine kinase activity(GO:0004111)
0.6 5.6 GO:0030274 LIM domain binding(GO:0030274)
0.6 6.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.6 3.0 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 2.3 GO:0043532 angiostatin binding(GO:0043532)
0.5 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 5.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5 1.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.5 1.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 2.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4 5.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 15.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 1.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 4.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.4 1.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 5.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 1.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 1.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 2.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.3 1.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 1.0 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.3 2.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 6.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 1.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.3 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 1.5 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 4.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 6.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.7 GO:0035500 MH2 domain binding(GO:0035500)
0.2 3.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 8.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.9 GO:0050811 GABA receptor binding(GO:0050811)
0.2 1.8 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 0.8 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.2 2.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 10.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 0.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 1.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.2 0.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 3.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.7 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.2 1.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 3.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 2.3 GO:0031005 filamin binding(GO:0031005)
0.2 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 15.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 2.6 GO:0046625 sphingolipid binding(GO:0046625)
0.1 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 7.9 GO:0030507 spectrin binding(GO:0030507)
0.1 2.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 2.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.6 GO:0030552 cAMP binding(GO:0030552)
0.1 1.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 3.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 4.1 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0002135 CTP binding(GO:0002135) TPR domain binding(GO:0030911)
0.1 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 3.5 GO:0050699 WW domain binding(GO:0050699)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 5.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.5 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.8 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 2.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 4.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 2.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 0.6 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 1.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 6.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 9.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0008187 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 17.5 GO:0003779 actin binding(GO:0003779)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 6.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 2.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 4.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 3.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 3.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 2.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 7.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 7.4 PID_FGF_PATHWAY FGF signaling pathway
0.1 1.2 PID_ALK2_PATHWAY ALK2 signaling events
0.1 0.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.1 0.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 13.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 2.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.1 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 2.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 7.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 6.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 2.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 0.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 0.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 2.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.9 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_RHOA_PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.3 10.1 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.1 17.1 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.9 7.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 5.9 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.5 15.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.4 5.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 10.0 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.3 11.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.3 3.9 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 9.2 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 5.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 5.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 2.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 9.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.5 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 5.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 0.5 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 2.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 1.7 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 1.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.9 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.4 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 5.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.7 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.6 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.7 REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 1.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 3.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.2 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 4.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.8 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.4 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.1 1.7 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 2.0 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 1.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.5 REACTOME_GABA_B_RECEPTOR_ACTIVATION Genes involved in GABA B receptor activation
0.0 3.4 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 2.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME_SHC_RELATED_EVENTS Genes involved in SHC-related events
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 7.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME_SIGNALING_BY_ERBB2 Genes involved in Signaling by ERBB2
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 1.0 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.9 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.3 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_AMYLOIDS Genes involved in Amyloids