Motif ID: Pparg_Rxrg

Z-value: 1.754

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598384_1675984110.163.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_77894096 18.766 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr5_-_115119277 14.095 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr17_+_35049966 12.314 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr11_+_80300866 10.915 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr9_+_118506226 10.091 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr4_+_126556935 9.657 ENSMUST00000048391.8
Clspn
claspin
chr13_-_24761861 8.869 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr11_+_61485431 8.624 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr2_-_79456750 8.513 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr4_-_126736236 8.347 ENSMUST00000048194.7
Tfap2e
transcription factor AP-2, epsilon
chr1_-_138847579 7.852 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr4_+_9269285 7.559 ENSMUST00000038841.7
Clvs1
clavesin 1
chr3_+_87948666 7.346 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr11_-_100354040 7.235 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr4_+_126556994 7.127 ENSMUST00000147675.1
Clspn
claspin
chr14_+_54476100 6.662 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr14_-_67715585 5.796 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr6_+_83137089 5.697 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr2_-_26516620 5.455 ENSMUST00000132820.1
Notch1
notch 1
chr11_-_100759942 5.297 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_+_59581563 5.274 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr7_-_143756985 5.260 ENSMUST00000134056.1
Osbpl5
oxysterol binding protein-like 5
chr10_+_128790903 5.109 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr11_+_23666479 5.052 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr2_+_126556128 5.048 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr13_+_108316332 4.961 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr14_-_52020698 4.931 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chrX_-_109013389 4.904 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr3_+_94693556 4.746 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr11_-_70015346 4.655 ENSMUST00000018718.7
ENSMUST00000102574.3
Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr7_+_4925802 4.491 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr14_-_21989475 4.484 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr19_-_43912392 4.356 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr13_+_108316395 4.301 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr11_-_70656467 4.224 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr12_+_109452833 4.156 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr3_-_100969644 4.150 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr2_+_165595009 4.141 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr7_+_45216671 4.034 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr2_-_151973387 3.983 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr3_+_108383829 3.969 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chr9_+_64117147 3.940 ENSMUST00000034969.7
Lctl
lactase-like
chr18_-_88927447 3.922 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr2_+_118598209 3.922 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr11_-_100939357 3.854 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr19_+_4594312 3.846 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr1_+_6487231 3.822 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr3_+_135212557 3.800 ENSMUST00000062893.7
Cenpe
centromere protein E
chr4_+_110397661 3.793 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr11_-_100939540 3.764 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr3_-_27153861 3.752 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr15_+_25773985 3.746 ENSMUST00000125667.1
Myo10
myosin X
chr5_-_53707532 3.744 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr18_-_41951187 3.721 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr17_+_86963279 3.713 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr1_+_191821444 3.712 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr11_-_100939457 3.670 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr6_+_114282635 3.602 ENSMUST00000032454.5
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr12_-_45074112 3.599 ENSMUST00000120531.1
ENSMUST00000143376.1
Stxbp6

syntaxin binding protein 6 (amisyn)

chr4_+_118429701 3.595 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr1_+_136467958 3.590 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr11_+_23666007 3.578 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chr4_+_131873608 3.557 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr6_-_48841373 3.556 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr2_-_117342831 3.552 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr17_+_32621319 3.536 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr3_-_27153844 3.493 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr6_+_48841476 3.474 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr5_+_3344194 3.461 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chrX_+_134308084 3.459 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr9_-_42399709 3.454 ENSMUST00000160940.1
Tecta
tectorin alpha
chr14_+_59201209 3.437 ENSMUST00000173547.1
ENSMUST00000043227.6
ENSMUST00000022551.7
Rcbtb1


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1


chr11_-_5261558 3.414 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr1_-_55226768 3.412 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr6_+_34384218 3.410 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr9_-_42399915 3.407 ENSMUST00000042190.7
Tecta
tectorin alpha
chr4_-_41697040 3.385 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr6_+_48841633 3.357 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr4_-_155043143 3.355 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr14_+_52016849 3.348 ENSMUST00000100638.2
Tmem253
transmembrane protein 253
chr2_+_152081529 3.344 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr6_+_7844806 3.313 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr17_-_56290499 3.303 ENSMUST00000019726.6
Plin3
perilipin 3
chr7_-_132813528 3.293 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr3_-_79628660 3.291 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr5_+_124862674 3.286 ENSMUST00000111417.2
Zfp664
zinc finger protein 664
chr10_-_80261004 3.203 ENSMUST00000105363.1
Gamt
guanidinoacetate methyltransferase
chr4_+_110397764 3.203 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chrX_-_142306170 3.164 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr9_-_72111827 3.151 ENSMUST00000183404.1
ENSMUST00000184783.1
Tcf12

transcription factor 12

chr11_-_102579461 3.149 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr4_+_59581645 3.109 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_-_110287479 3.086 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr2_-_38287347 3.083 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr3_-_27153782 3.069 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr11_+_49203285 3.049 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr7_+_31059342 3.027 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr17_-_57078490 2.970 ENSMUST00000011623.7
Dennd1c
DENN/MADD domain containing 1C
chr3_-_153944425 2.964 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr3_-_153944632 2.959 ENSMUST00000072697.6
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr15_-_89425856 2.957 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr6_+_34354119 2.956 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr11_+_44617310 2.931 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_-_132813095 2.930 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr10_+_112271123 2.902 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr2_+_165655237 2.902 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr11_-_34833631 2.873 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr5_+_110286306 2.873 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr10_-_80260959 2.842 ENSMUST00000020359.6
Gamt
guanidinoacetate methyltransferase
chr6_+_34709442 2.794 ENSMUST00000115021.1
Cald1
caldesmon 1
chr4_-_132422484 2.746 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr4_-_132422394 2.728 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr7_+_127211608 2.724 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_+_80165079 2.707 ENSMUST00000184480.1
Myo6
myosin VI
chr2_+_145785980 2.690 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr7_-_25477607 2.672 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr12_+_59130767 2.661 ENSMUST00000175877.1
Ctage5
CTAGE family, member 5
chr9_+_80165013 2.650 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr2_-_127521358 2.647 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chr9_-_72111755 2.638 ENSMUST00000183492.1
ENSMUST00000184523.1
ENSMUST00000034755.6
Tcf12


transcription factor 12


chr7_-_142899985 2.604 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr11_+_72042455 2.581 ENSMUST00000021164.3
Fam64a
family with sequence similarity 64, member A
chr4_+_141010644 2.579 ENSMUST00000071977.8
Mfap2
microfibrillar-associated protein 2
chr6_+_34709610 2.566 ENSMUST00000031775.6
Cald1
caldesmon 1
chr3_-_59344256 2.552 ENSMUST00000039419.6
Igsf10
immunoglobulin superfamily, member 10
chr3_+_88214474 2.548 ENSMUST00000181356.1
ENSMUST00000181396.1
Gm3764

predicted gene 3764

chr6_-_38837224 2.548 ENSMUST00000160962.1
Hipk2
homeodomain interacting protein kinase 2
chr12_+_59130994 2.533 ENSMUST00000177460.1
Ctage5
CTAGE family, member 5
chr12_+_59131286 2.532 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr5_-_130024280 2.531 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr9_-_72111651 2.531 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr17_-_23844155 2.518 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41


chr2_-_154603698 2.516 ENSMUST00000000896.4
Pxmp4
peroxisomal membrane protein 4
chr4_-_43558386 2.484 ENSMUST00000130353.1
Tln1
talin 1
chr3_-_108722281 2.463 ENSMUST00000029482.9
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr2_-_38287174 2.456 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr5_-_120467296 2.440 ENSMUST00000132916.1
Sdsl
serine dehydratase-like
chr1_-_133424377 2.435 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chrX_+_137049586 2.431 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr3_+_122729158 2.429 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr15_+_79895017 2.421 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr13_-_64248495 2.384 ENSMUST00000109769.2
Cdc14b
CDC14 cell division cycle 14B
chr3_+_94933041 2.376 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr18_+_50053282 2.373 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr2_-_105399286 2.354 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chrX_+_101254528 2.333 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr4_-_108833608 2.330 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr7_+_16842896 2.328 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr16_-_46010212 2.327 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_-_18950932 2.323 ENSMUST00000055503.5
ENSMUST00000095438.3
Xkr5

X Kell blood group precursor-related family, member 5

chr9_-_55048544 2.321 ENSMUST00000034854.6
Chrnb4
cholinergic receptor, nicotinic, beta polypeptide 4
chr14_+_122181694 2.312 ENSMUST00000026625.5
Clybl
citrate lyase beta like
chr7_-_103843154 2.306 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr19_+_46707443 2.302 ENSMUST00000003655.7
As3mt
arsenic (+3 oxidation state) methyltransferase
chr14_+_31134853 2.286 ENSMUST00000090212.4
Nt5dc2
5'-nucleotidase domain containing 2
chr12_+_17690793 2.257 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr9_+_108479849 2.219 ENSMUST00000065014.4
Lamb2
laminin, beta 2
chr11_+_70657687 2.218 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr3_-_87174657 2.210 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr9_+_46012810 2.207 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr14_+_75455957 2.198 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr2_+_154436437 2.193 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr6_-_5256226 2.189 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3

paraoxonase 3

chr1_-_120120138 2.168 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr7_+_141468776 2.156 ENSMUST00000058746.5
Cd151
CD151 antigen
chr8_-_105484350 2.151 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr9_-_55512156 2.126 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr14_+_67716095 2.096 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr7_+_114768736 2.095 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr3_+_156562141 2.083 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr6_-_125313844 2.071 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr7_+_139400489 2.071 ENSMUST00000097975.2
Inpp5a
inositol polyphosphate-5-phosphatase A
chr11_-_86993682 2.070 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr4_+_43875524 2.055 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr5_-_36988922 2.024 ENSMUST00000166339.1
ENSMUST00000043964.6
Wfs1

Wolfram syndrome 1 homolog (human)

chr1_+_171113918 1.978 ENSMUST00000129651.1
ENSMUST00000151340.1
1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr11_+_84525669 1.973 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_115154139 1.964 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr19_+_36554661 1.954 ENSMUST00000169036.2
ENSMUST00000047247.5
Hectd2

HECT domain containing 2

chr9_-_50739365 1.952 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chrX_+_73639414 1.944 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr5_+_122209729 1.930 ENSMUST00000072602.7
ENSMUST00000143560.1
Hvcn1

hydrogen voltage-gated channel 1

chr10_-_127288851 1.914 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr14_+_54640952 1.912 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr12_-_45074457 1.897 ENSMUST00000053768.6
Stxbp6
syntaxin binding protein 6 (amisyn)
chr6_+_38433913 1.896 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chr1_-_136234113 1.895 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr2_+_102706356 1.887 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr16_+_84834901 1.886 ENSMUST00000114184.1
Gabpa
GA repeat binding protein, alpha
chr10_-_13324160 1.845 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr5_+_122210134 1.833 ENSMUST00000100747.2
Hvcn1
hydrogen voltage-gated channel 1
chr11_-_95041335 1.831 ENSMUST00000038431.7
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr9_+_107576915 1.808 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr11_+_84525647 1.800 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr2_-_160872829 1.783 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr15_-_102189032 1.773 ENSMUST00000023805.1
Csad
cysteine sulfinic acid decarboxylase
chr1_+_74601548 1.767 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr10_-_81202037 1.759 ENSMUST00000005069.6
Nmrk2
nicotinamide riboside kinase 2
chr3_-_87174518 1.758 ENSMUST00000041732.8
Kirrel
kin of IRRE like (Drosophila)
chr4_-_149485157 1.756 ENSMUST00000126896.1
ENSMUST00000105693.1
ENSMUST00000030845.6
Nmnat1


nicotinamide nucleotide adenylyltransferase 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 18.8 GO:0006553 lysine metabolic process(GO:0006553)
2.8 11.3 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
2.1 8.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
2.0 6.0 GO:0006601 creatine biosynthetic process(GO:0006601)
2.0 18.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.0 5.9 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
1.8 5.5 GO:0003162 atrioventricular node development(GO:0003162)
1.7 7.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.7 5.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.6 26.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.6 7.9 GO:0035262 gonad morphogenesis(GO:0035262)
1.5 4.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.5 10.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.4 7.2 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.4 5.5 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.3 3.9 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.3 3.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.2 3.7 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
1.2 10.4 GO:0071493 cellular response to UV-B(GO:0071493)
1.1 3.4 GO:0003360 brainstem development(GO:0003360)
1.1 10.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.0 1.0 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324)
1.0 17.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.0 3.0 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
1.0 7.8 GO:0016576 histone dephosphorylation(GO:0016576)
1.0 2.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.0 2.9 GO:0045004 DNA replication proofreading(GO:0045004)
0.9 5.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.9 3.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.9 2.7 GO:2001187 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.8 2.5 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.8 2.4 GO:0060282 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of oocyte development(GO:0060282)
0.8 2.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.8 3.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.7 4.5 GO:2000483 detection of bacterium(GO:0016045) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483)
0.7 7.3 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.7 5.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.7 2.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.7 6.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.6 3.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.6 2.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.6 2.4 GO:0042414 epinephrine metabolic process(GO:0042414)
0.6 3.6 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.6 1.8 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.6 4.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.6 1.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.6 3.3 GO:0016266 O-glycan processing(GO:0016266)
0.5 3.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.5 1.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 1.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.5 2.3 GO:0015671 oxygen transport(GO:0015671)
0.5 1.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.5 3.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 3.1 GO:0032596 protein transport into membrane raft(GO:0032596)
0.4 2.2 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.4 2.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.4 1.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.4 1.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 2.4 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.4 1.2 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.4 2.8 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.4 3.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.4 1.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.4 2.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4 1.9 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4 1.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.4 2.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.7 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.3 3.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 2.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3 1.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 2.4 GO:0030242 pexophagy(GO:0030242)
0.3 1.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.3 3.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.3 1.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 1.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 2.4 GO:0007296 vitellogenesis(GO:0007296)
0.3 1.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 3.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.3 1.0 GO:0000237 leptotene(GO:0000237)
0.3 13.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 3.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.5 GO:0042940 D-amino acid transport(GO:0042940)
0.3 2.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 5.1 GO:0030574 collagen catabolic process(GO:0030574)
0.3 1.2 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.3 1.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.3 0.9 GO:0046104 thymidine metabolic process(GO:0046104)
0.3 2.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 1.1 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.3 1.4 GO:1903232 melanosome assembly(GO:1903232)
0.3 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 1.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.3 1.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.3 4.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.3 2.4 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.3 1.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 1.5 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.2 1.2 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 1.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 2.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 1.7 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.2 1.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.7 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 2.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 0.7 GO:0042711 maternal behavior(GO:0042711)
0.2 1.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 1.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.6 GO:1902969 DNA replication, Okazaki fragment processing(GO:0033567) mitotic DNA replication(GO:1902969)
0.2 0.2 GO:0039519 modulation by virus of host autophagy(GO:0039519)
0.2 3.3 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 2.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 11.5 GO:0015914 phospholipid transport(GO:0015914)
0.2 1.1 GO:1990839 response to endothelin(GO:1990839)
0.2 1.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.6 GO:0042732 D-xylose metabolic process(GO:0042732)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 2.4 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.2 0.8 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.2 0.8 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 2.4 GO:0009404 toxin metabolic process(GO:0009404)
0.2 2.5 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 2.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.6 GO:0008228 opsonization(GO:0008228)
0.2 9.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 1.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 1.0 GO:2000252 progesterone secretion(GO:0042701) negative regulation of feeding behavior(GO:2000252)
0.2 0.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 0.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 4.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.7 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 0.7 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 1.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 1.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 3.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.2 1.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 2.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 0.5 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.2 0.5 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 1.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 2.1 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.2 0.3 GO:2000152 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of ubiquitin-specific protease activity(GO:2000152) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 7.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.2 6.7 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 1.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 0.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.2 GO:0032306 regulation of prostaglandin secretion(GO:0032306)
0.1 0.6 GO:0015793 glycerol transport(GO:0015793)
0.1 3.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.0 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 2.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 8.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 1.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 1.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.4 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 4.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 3.5 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.6 GO:0010224 response to UV-B(GO:0010224)
0.1 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.3 GO:0007141 male meiosis I(GO:0007141)
0.1 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 5.3 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 3.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 1.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 1.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.2 GO:1902302 regulation of potassium ion export(GO:1902302)
0.1 0.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0060290 transdifferentiation(GO:0060290)
0.1 3.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.9 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.5 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 1.7 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 3.3 GO:0007588 excretion(GO:0007588)
0.1 2.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 1.9 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 1.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 1.8 GO:0001967 suckling behavior(GO:0001967)
0.1 0.5 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 6.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 0.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.9 GO:0050892 intestinal absorption(GO:0050892)
0.1 1.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 1.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.7 GO:1900193 receptor guanylyl cyclase signaling pathway(GO:0007168) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.8 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.5 GO:0060539 diaphragm development(GO:0060539)
0.1 0.2 GO:2000858 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.8 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 0.1 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 4.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.4 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.1 2.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 1.2 GO:0043486 histone exchange(GO:0043486)
0.1 1.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 2.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.2 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 1.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 5.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.1 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 2.5 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 3.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1 7.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 0.1 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 1.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.5 GO:0010043 response to zinc ion(GO:0010043)
0.1 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 2.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 3.7 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.1 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 1.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.4 GO:0032620 interleukin-17 production(GO:0032620)
0.0 1.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.6 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.6 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 2.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0090282 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.3 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.6 GO:0060021 palate development(GO:0060021)
0.0 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 2.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.9 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.6 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0071953 elastic fiber(GO:0071953)
2.1 10.3 GO:0097149 centralspindlin complex(GO:0097149)
2.0 8.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
1.3 4.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.2 2.3 GO:0005833 hemoglobin complex(GO:0005833)
1.1 3.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.1 5.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 2.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.8 10.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 1.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.6 5.4 GO:0030478 actin cap(GO:0030478)
0.6 2.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 1.8 GO:0032021 NELF complex(GO:0032021)
0.4 2.2 GO:0043256 laminin complex(GO:0043256)
0.3 0.7 GO:0051286 cell tip(GO:0051286)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 1.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 1.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 3.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 1.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 1.2 GO:0014802 terminal cisterna(GO:0014802)
0.3 1.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 2.0 GO:0001740 Barr body(GO:0001740)
0.3 1.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 1.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 4.7 GO:0000145 exocyst(GO:0000145)
0.2 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 3.6 GO:0051233 spindle midzone(GO:0051233)
0.2 1.1 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.2 2.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 3.3 GO:0032993 protein-DNA complex(GO:0032993)
0.2 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.2 7.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.2 29.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 0.5 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.2 1.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.6 GO:1990037 Lewy body core(GO:1990037)
0.2 4.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 29.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 2.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.8 GO:0097165 nuclear stress granule(GO:0097165)
0.1 12.8 GO:0005814 centriole(GO:0005814)
0.1 1.1 GO:0001739 sex chromatin(GO:0001739)
0.1 1.2 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 5.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.9 GO:0010369 chromocenter(GO:0010369)
0.1 0.7 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 8.5 GO:0000922 spindle pole(GO:0000922)
0.1 3.3 GO:0001772 immunological synapse(GO:0001772)
0.1 1.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.2 GO:0016459 myosin complex(GO:0016459)
0.1 3.2 GO:0030673 axolemma(GO:0030673)
0.1 2.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 6.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.2 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0016460 myosin II complex(GO:0016460)
0.1 2.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.4 GO:0031082 BLOC complex(GO:0031082)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0031045 dense core granule(GO:0031045)
0.1 1.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.3 GO:0005844 polysome(GO:0005844)
0.0 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.7 GO:0005903 brush border(GO:0005903)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.3 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 4.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 10.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 3.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 24.2 GO:0005694 chromosome(GO:0005694)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 3.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 3.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.8 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
3.0 5.9 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
2.8 16.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.6 4.7 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
1.3 6.7 GO:0043515 kinetochore binding(GO:0043515)
1.3 6.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.3 3.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.2 3.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.2 3.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.2 3.5 GO:0098770 FBXO family protein binding(GO:0098770)
1.1 4.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.1 10.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.1 3.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.1 5.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
1.1 4.3 GO:0008422 beta-glucosidase activity(GO:0008422)
1.0 13.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
1.0 2.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.9 4.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.9 5.2 GO:0019841 retinol binding(GO:0019841)
0.8 3.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.7 2.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.7 5.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.7 5.2 GO:0046790 virion binding(GO:0046790)
0.6 7.1 GO:0008430 selenium binding(GO:0008430)
0.6 3.8 GO:0009374 biotin binding(GO:0009374)
0.6 2.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 6.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6 10.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.6 2.4 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.6 2.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.6 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 1.8 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.6 1.8 GO:0005118 sevenless binding(GO:0005118)
0.6 2.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.6 4.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.6 1.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 2.2 GO:0004064 arylesterase activity(GO:0004064)
0.5 2.6 GO:0035240 dopamine binding(GO:0035240)
0.5 2.5 GO:0070051 fibrinogen binding(GO:0070051)
0.5 1.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 8.5 GO:0035497 cAMP response element binding(GO:0035497)
0.4 3.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.4 1.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.4 2.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 1.6 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.4 6.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 4.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 3.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 2.1 GO:0042731 PH domain binding(GO:0042731)
0.3 1.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.3 1.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 3.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 3.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 2.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 7.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 3.8 GO:0005522 profilin binding(GO:0005522)
0.3 2.5 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 3.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 3.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 1.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 1.7 GO:0031432 titin binding(GO:0031432)
0.2 4.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 4.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.5 GO:0004075 biotin carboxylase activity(GO:0004075)
0.2 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 4.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 2.1 GO:0001727 lipid kinase activity(GO:0001727)
0.2 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 7.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 14.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 15.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 0.7 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 8.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 1.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.2 4.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 7.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 3.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.9 GO:0002054 nucleobase binding(GO:0002054)
0.1 2.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 8.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 2.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 2.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 1.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 9.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 1.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 7.8 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 2.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 3.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 3.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.0 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.1 3.3 GO:0000975 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.1 4.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 6.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 9.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.1 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 4.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.9 GO:0005267 potassium channel activity(GO:0005267)
0.1 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:0097001 ceramide binding(GO:0097001)
0.1 5.0 GO:0005178 integrin binding(GO:0005178)
0.1 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 7.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 2.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0043176 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) amine binding(GO:0043176)
0.0 1.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 3.0 GO:0001047 core promoter binding(GO:0001047)
0.0 4.0 GO:0004386 helicase activity(GO:0004386)
0.0 7.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 4.8 GO:0042393 histone binding(GO:0042393)
0.0 2.6 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.5 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 4.0 GO:0008017 microtubule binding(GO:0008017)
0.0 4.6 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0035326 enhancer binding(GO:0035326)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 4.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 37.2 PID_PLK1_PATHWAY PLK1 signaling events
0.6 10.1 ST_STAT3_PATHWAY STAT3 Pathway
0.4 18.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 0.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.3 2.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.2 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 3.5 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 4.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 7.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 6.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 4.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 16.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.0 PID_BARD1_PATHWAY BARD1 signaling events
0.1 2.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 1.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 6.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID_ATM_PATHWAY ATM pathway
0.0 1.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 2.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.4 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.8 10.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.6 5.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 8.9 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 2.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 3.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 7.6 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 3.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.3 5.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.3 7.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.4 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 0.6 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.2 4.3 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 7.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 7.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 2.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.9 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 7.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.2 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 3.0 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 4.6 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 4.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.4 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 4.3 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 0.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 5.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 6.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.6 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 13.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.1 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 2.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.6 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ Genes involved in Formation of RNA Pol II elongation complex
0.0 1.1 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.6 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway