Motif ID: Prdm1

Z-value: 0.942


Transcription factors associated with Prdm1:

Gene SymbolEntrez IDGene Name
Prdm1 ENSMUSG00000038151.6 Prdm1



Activity profile for motif Prdm1.

activity profile for motif Prdm1


Sorted Z-values histogram for motif Prdm1

Sorted Z-values for motif Prdm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84800024 5.482 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr4_-_154636831 5.443 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr8_-_84800344 5.382 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr4_+_48049080 4.691 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr3_-_107760221 4.628 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr5_+_3343893 4.237 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr1_-_156674290 4.125 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr1_-_56978534 3.695 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr2_+_116067213 3.675 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr16_+_43363855 3.558 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr15_+_32920723 3.477 ENSMUST00000022871.5
Sdc2
syndecan 2
chr13_-_23430826 3.428 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr11_-_77894096 3.307 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr9_-_107668967 3.114 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr6_+_117168535 3.048 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr16_+_43364145 3.035 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_-_101604580 2.603 ENSMUST00000036493.6
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_-_39118211 2.446 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr4_-_96591555 2.368 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr12_+_83987854 2.329 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr9_+_38718263 2.258 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr2_-_116067391 2.240 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_171234290 1.852 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr17_-_25785533 1.832 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
Haghl




hydroxyacylglutathione hydrolase-like




chr14_+_76487759 1.809 ENSMUST00000142683.1
Tsc22d1
TSC22 domain family, member 1
chr10_-_75797728 1.779 ENSMUST00000139724.1
Gstt1
glutathione S-transferase, theta 1
chr1_+_153749414 1.717 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr1_+_153749496 1.690 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr8_+_66697404 1.686 ENSMUST00000039303.5
Npy1r
neuropeptide Y receptor Y1
chr10_-_75797528 1.626 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr11_+_3514861 1.585 ENSMUST00000094469.4
Selm
selenoprotein M
chr8_+_46739745 1.541 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr5_+_30921867 1.519 ENSMUST00000123885.1
Khk
ketohexokinase
chr7_-_102250086 1.490 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr11_+_3330781 1.486 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr6_+_4003926 1.473 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr3_-_9833617 1.460 ENSMUST00000108384.2
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_-_191183244 1.428 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr3_-_94412883 1.396 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr7_+_45017953 1.293 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr8_-_105938384 1.291 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr2_+_27886416 1.275 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr11_+_121702393 1.274 ENSMUST00000036742.7
Metrnl
meteorin, glial cell differentiation regulator-like
chr3_-_9833653 1.256 ENSMUST00000161949.1
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr10_+_81574699 1.245 ENSMUST00000131794.1
ENSMUST00000136341.1
Tle2

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

chr7_-_19118357 1.224 ENSMUST00000141380.1
Gm4969
predicted gene 4969
chr15_-_72546279 1.189 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr5_+_30921825 1.136 ENSMUST00000117435.1
Khk
ketohexokinase
chr3_+_81932601 1.116 ENSMUST00000029649.2
Ctso
cathepsin O
chrX_+_166344692 1.087 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr3_-_113574758 1.083 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr19_+_36409719 0.996 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr13_+_74639866 0.974 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr5_+_30921556 0.972 ENSMUST00000031053.8
Khk
ketohexokinase
chr2_-_51972990 0.964 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr2_-_26640230 0.949 ENSMUST00000181621.1
ENSMUST00000180659.1
Snhg7

small nucleolar RNA host gene (non-protein coding) 7

chr11_-_82991829 0.945 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr16_+_35938972 0.927 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr1_-_106759727 0.848 ENSMUST00000010049.4
Kdsr
3-ketodihydrosphingosine reductase
chr11_+_103103051 0.825 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chrX_-_74023908 0.808 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1




interleukin-1 receptor-associated kinase 1




chr1_+_171113918 0.807 ENSMUST00000129651.1
ENSMUST00000151340.1
1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr4_+_154170730 0.805 ENSMUST00000030897.8
Megf6
multiple EGF-like-domains 6
chr17_+_21008921 0.805 ENSMUST00000088811.5
Zfp160
zinc finger protein 160
chr8_-_53638945 0.800 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr13_-_12464925 0.799 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr2_-_175131864 0.795 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr5_-_5694024 0.780 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr5_-_115119277 0.765 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr8_-_111522073 0.757 ENSMUST00000034437.6
ENSMUST00000038193.7
Wdr59

WD repeat domain 59

chr2_-_51973219 0.755 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr2_-_59948155 0.748 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr10_-_80320506 0.731 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr14_-_45477856 0.720 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr16_-_91044473 0.715 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr17_+_33919332 0.714 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr11_+_119267887 0.705 ENSMUST00000106259.2
Gaa
glucosidase, alpha, acid
chr5_+_109940426 0.699 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr11_+_119268004 0.695 ENSMUST00000026666.6
ENSMUST00000106258.1
Gaa

glucosidase, alpha, acid

chr15_-_89379246 0.684 ENSMUST00000049968.7
Odf3b
outer dense fiber of sperm tails 3B
chr11_-_53707269 0.661 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr16_+_24393350 0.649 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr16_-_24393588 0.648 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr2_-_91070180 0.622 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr1_+_171840607 0.614 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr14_+_64652524 0.609 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr15_+_5143861 0.607 ENSMUST00000051186.8
Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chrX_-_77795921 0.587 ENSMUST00000114044.1
Prkx
protein kinase, X-linked
chr11_-_82991137 0.586 ENSMUST00000138797.1
Slfn9
schlafen 9
chr7_+_30184160 0.582 ENSMUST00000098594.2
Cox7a1
cytochrome c oxidase subunit VIIa 1
chrX_-_150812932 0.578 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
Maged2


melanoma antigen, family D, 2


chr17_+_94873986 0.574 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr1_-_140183283 0.573 ENSMUST00000111977.1
Cfh
complement component factor h
chr1_+_181150926 0.573 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr5_-_86172747 0.570 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr6_+_71373400 0.562 ENSMUST00000066747.7
ENSMUST00000172321.1
Cd8a

CD8 antigen, alpha chain

chr10_+_81718919 0.549 ENSMUST00000085664.5
Zfp433
RIKEN cDNA 1700123A16 gene
chr2_-_91070283 0.548 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr5_+_147188678 0.547 ENSMUST00000065382.5
Gsx1
GS homeobox 1
chr1_-_93801840 0.544 ENSMUST00000112890.2
ENSMUST00000027503.7
Dtymk

deoxythymidylate kinase

chr1_+_180942452 0.536 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr14_+_14012491 0.527 ENSMUST00000022257.2
Atxn7
ataxin 7
chr14_-_25927250 0.520 ENSMUST00000100811.5
Tmem254a
transmembrane protein 254a
chr11_+_70562980 0.519 ENSMUST00000079244.5
ENSMUST00000102558.4
Mink1

misshapen-like kinase 1 (zebrafish)

chr13_-_56895737 0.508 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr10_-_78352323 0.492 ENSMUST00000001240.5
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_-_105399286 0.482 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr4_+_133011506 0.479 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr14_+_55578123 0.479 ENSMUST00000174484.1
Psme1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr4_-_52497244 0.475 ENSMUST00000114578.4
Vma21-ps
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene
chr14_+_56575603 0.471 ENSMUST00000161553.1
Parp4
poly (ADP-ribose) polymerase family, member 4
chr5_+_135168283 0.462 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr7_-_145283915 0.461 ENSMUST00000058022.4
Tpcn2
two pore segment channel 2
chr10_-_127288851 0.445 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr10_-_78352053 0.441 ENSMUST00000105388.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_+_55894508 0.436 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_+_24973419 0.426 ENSMUST00000038920.1
Gpr63
G protein-coupled receptor 63
chr18_-_41951187 0.424 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr19_-_5875268 0.424 ENSMUST00000025728.6
Frmd8
FERM domain containing 8
chr15_+_85510812 0.423 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chrX_-_142966709 0.422 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr9_+_98296556 0.419 ENSMUST00000035031.6
ENSMUST00000112935.1
Nmnat3

nicotinamide nucleotide adenylyltransferase 3

chr16_+_20141061 0.415 ENSMUST00000115560.2
ENSMUST00000090052.4
Yeats2

YEATS domain containing 2

chr2_+_14388316 0.413 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr4_-_137796350 0.410 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr5_+_28165690 0.405 ENSMUST00000036177.7
En2
engrailed 2
chr2_-_119477613 0.396 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr5_-_3893907 0.396 ENSMUST00000117463.1
ENSMUST00000044746.4
Mterf

mitochondrial transcription termination factor

chr17_+_15053059 0.392 ENSMUST00000040594.8
Ermard
ER membrane associated RNA degradation
chr15_+_25843264 0.389 ENSMUST00000022881.7
Fam134b
family with sequence similarity 134, member B
chr14_+_55578360 0.389 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr10_-_78351690 0.388 ENSMUST00000166360.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_61638819 0.378 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr3_+_106721672 0.376 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chrX_+_75095854 0.373 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr7_+_128265675 0.373 ENSMUST00000118169.1
ENSMUST00000142841.1
Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

chr16_-_38713235 0.365 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr11_+_75468040 0.364 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr14_-_26066961 0.363 ENSMUST00000100818.5
Tmem254c
transmembrane protein 254c
chr10_-_78351711 0.360 ENSMUST00000105390.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_12922290 0.359 ENSMUST00000108539.1
ENSMUST00000004554.7
ENSMUST00000147435.1
ENSMUST00000137329.1
Rps5



ribosomal protein S5



chrX_+_161717055 0.347 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr3_+_106721893 0.339 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr4_-_26346882 0.335 ENSMUST00000041374.7
ENSMUST00000153813.1
Manea

mannosidase, endo-alpha

chr1_-_184845838 0.334 ENSMUST00000068725.3
Marc2
mitochondrial amidoxime reducing component 2
chr17_-_24895047 0.326 ENSMUST00000119848.1
ENSMUST00000121542.1
Eme2

essential meiotic endonuclease 1 homolog 2 (S. pombe)

chr10_+_78069351 0.325 ENSMUST00000105393.1
Icosl
icos ligand
chr10_+_128225830 0.324 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr17_+_24895116 0.317 ENSMUST00000043907.7
Mrps34
mitochondrial ribosomal protein S34
chr19_+_5088534 0.314 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr8_-_45410539 0.308 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr18_-_12879973 0.301 ENSMUST00000119512.1
Osbpl1a
oxysterol binding protein-like 1A
chr1_-_184033998 0.291 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr14_+_118854695 0.288 ENSMUST00000100314.3
Cldn10
claudin 10
chr6_+_114648811 0.285 ENSMUST00000182510.1
Atg7
autophagy related 7
chr2_-_51934943 0.279 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr3_-_59262825 0.271 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_-_138170992 0.269 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_+_75096039 0.269 ENSMUST00000131155.1
ENSMUST00000132000.1
Dkc1

dyskeratosis congenita 1, dyskerin

chr10_-_22149270 0.261 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr5_-_105239533 0.258 ENSMUST00000065588.6
Gbp10
guanylate-binding protein 10
chr13_-_18031616 0.258 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr5_-_93206489 0.253 ENSMUST00000058550.8
Ccni
cyclin I
chr4_-_134552122 0.253 ENSMUST00000060435.6
Sepn1
selenoprotein N, 1
chr1_-_172590463 0.251 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr12_-_69357120 0.247 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr4_+_32615473 0.245 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr11_-_30025915 0.231 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr4_+_141115660 0.231 ENSMUST00000181450.1
4921514A10Rik
RIKEN cDNA 4921514A10 gene
chr1_+_72307413 0.220 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr1_-_161876656 0.212 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chr5_+_139211934 0.210 ENSMUST00000148772.1
ENSMUST00000110882.1
Sun1

Sad1 and UNC84 domain containing 1

chr1_-_79671966 0.204 ENSMUST00000162342.1
Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr2_-_106003549 0.204 ENSMUST00000102555.4
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr5_-_116024452 0.201 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_-_84662841 0.196 ENSMUST00000060427.4
Ier2
immediate early response 2
chr1_+_74544345 0.192 ENSMUST00000027362.7
Plcd4
phospholipase C, delta 4
chr17_+_46681038 0.190 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr4_+_42255767 0.189 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr7_-_5413145 0.186 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr10_+_80602865 0.182 ENSMUST00000038411.4
ENSMUST00000079883.4
Adat3
Scamp4
adenosine deaminase, tRNA-specific 3
secretory carrier membrane protein 4
chrX_+_7657260 0.182 ENSMUST00000033485.7
Prickle3
prickle homolog 3 (Drosophila)
chr11_+_102881204 0.176 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr11_+_87853207 0.175 ENSMUST00000038196.6
Mks1
Meckel syndrome, type 1
chr19_-_29367294 0.168 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr15_-_76243401 0.166 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr16_+_97536079 0.165 ENSMUST00000024112.7
Mx2
myxovirus (influenza virus) resistance 2
chr2_+_32535724 0.164 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr8_-_94434259 0.163 ENSMUST00000180445.1
9330175E14Rik
RIKEN cDNA 9330175E14 gene
chr1_+_132008285 0.158 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr10_+_128322443 0.156 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr4_-_42773993 0.155 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr4_-_129623870 0.155 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B


chr11_+_70459940 0.151 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chrX_-_134111852 0.150 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr8_+_88697022 0.145 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr5_-_148995147 0.137 ENSMUST00000147473.1
Katnal1
katanin p60 subunit A-like 1
chr2_-_90904827 0.135 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr2_-_167188787 0.130 ENSMUST00000059826.8
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr9_-_50617428 0.130 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
1.6 4.9 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.2 3.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
1.1 3.4 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
1.1 3.3 GO:0006553 lysine metabolic process(GO:0006553)
0.8 6.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.8 3.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.7 2.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.7 2.6 GO:1903416 response to glycoside(GO:1903416)
0.6 3.1 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.6 4.2 GO:0044838 cell quiescence(GO:0044838)
0.6 10.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 1.4 GO:0043181 vacuolar sequestering(GO:0043181)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 2.3 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 3.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.2 3.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 0.6 GO:0021764 amygdala development(GO:0021764)
0.2 1.8 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.5 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 1.7 GO:0030432 peristalsis(GO:0030432)
0.2 6.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 1.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 1.7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.8 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.1 0.6 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.9 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.1 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.6 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.6 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.1 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.1 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.6 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.5 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.1 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.1 0.8 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 1.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.7 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.9 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.6 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.6 GO:1990403 embryonic brain development(GO:1990403)
0.0 2.6 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0090646 RNA 5'-end processing(GO:0000966) mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 3.0 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 1.3 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.8 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0009451 RNA modification(GO:0009451)
0.0 1.8 GO:0008654 phospholipid biosynthetic process(GO:0008654)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 2.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 5.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.2 GO:0016235 aggresome(GO:0016235)
0.1 0.7 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 5.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 3.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 7.3 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0030133 transport vesicle(GO:0030133)
0.0 0.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0098770 FBXO family protein binding(GO:0098770)
1.2 3.6 GO:0004454 ketohexokinase activity(GO:0004454)
1.1 3.4 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
1.0 3.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.8 3.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 1.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.5 1.9 GO:0019863 IgE binding(GO:0019863)
0.4 1.7 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.4 1.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.3 2.6 GO:1990239 steroid hormone binding(GO:1990239)
0.3 3.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 2.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 0.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 4.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.8 GO:0000405 bubble DNA binding(GO:0000405)
0.1 2.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.6 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 4.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.7 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 1.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 5.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 3.4 GO:0019843 rRNA binding(GO:0019843)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 7.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 13.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 2.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 3.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 4.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.7 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.9 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 1.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.9 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 4.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 4.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 3.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.4 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.7 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.0 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.7 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 1.7 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.4 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates