Motif ID: Prdm14

Z-value: 0.313


Transcription factors associated with Prdm14:

Gene SymbolEntrez IDGene Name
Prdm14 ENSMUSG00000042414.7 Prdm14



Activity profile for motif Prdm14.

activity profile for motif Prdm14


Sorted Z-values histogram for motif Prdm14

Sorted Z-values for motif Prdm14



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_43235856 1.420 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr6_+_72355425 0.986 ENSMUST00000069695.2
ENSMUST00000132243.1
 Tmem150a

transmembrane protein 150A

chr10_-_128744014 0.832 ENSMUST00000026414.7
 Dgka
diacylglycerol kinase, alpha
chr7_+_18987518 0.807 ENSMUST00000063563.7
 Nanos2
nanos homolog 2 (Drosophila)
chr12_+_74297474 0.733 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr4_-_88438900 0.705 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr15_+_18818895 0.701 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr7_+_114745685 0.698 ENSMUST00000136645.1
ENSMUST00000169913.1
 Insc

inscuteable homolog (Drosophila)

chr4_+_119814495 0.528 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr15_+_99601372 0.462 ENSMUST00000023754.5
 Aqp6
aquaporin 6
chr3_-_63851251 0.431 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr9_+_94669876 0.419 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_+_27810813 0.371 ENSMUST00000080175.6
 Zfp626
zinc finger protein 626
chrX_+_99042581 0.345 ENSMUST00000036606.7
 Stard8
START domain containing 8
chr11_+_78324200 0.336 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr15_-_76307231 0.309 ENSMUST00000023222.6
ENSMUST00000164189.1
 Oplah

5-oxoprolinase (ATP-hydrolysing)

chr15_-_76307101 0.278 ENSMUST00000171340.1
 Oplah
5-oxoprolinase (ATP-hydrolysing)
chr8_+_46492789 0.242 ENSMUST00000110371.1
 Acsl1
acyl-CoA synthetase long-chain family member 1
chr18_-_15063560 0.227 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr13_+_74639866 0.224 ENSMUST00000169114.1
 Erap1
endoplasmic reticulum aminopeptidase 1
chr18_+_37307445 0.216 ENSMUST00000056712.2
 Pcdhb4
protocadherin beta 4
chr15_-_50890396 0.199 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chrM_+_7759 0.181 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr17_+_33555719 0.171 ENSMUST00000087605.5
ENSMUST00000174695.1
 Myo1f

myosin IF

chr2_-_144011202 0.161 ENSMUST00000016072.5
ENSMUST00000037875.5
 Rrbp1

ribosome binding protein 1

chr1_+_88103229 0.151 ENSMUST00000113135.3
ENSMUST00000113138.1
 Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr18_-_70530138 0.143 ENSMUST00000161542.1
ENSMUST00000159389.1
 Poli

polymerase (DNA directed), iota

chr1_+_88134786 0.132 ENSMUST00000113134.1
ENSMUST00000140092.1
 Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr6_+_92940572 0.112 ENSMUST00000181145.1
ENSMUST00000181840.1
 9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr2_+_91730127 0.112 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
 Ambra1



autophagy/beclin 1 regulator 1



chr14_-_72709986 0.108 ENSMUST00000089017.5
 Fndc3a
fibronectin type III domain containing 3A
chr19_-_6067785 0.104 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
 Tm7sf2






transmembrane 7 superfamily member 2






chr1_-_64121389 0.095 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chrX_+_13280970 0.088 ENSMUST00000000804.6
 Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr18_-_70530313 0.083 ENSMUST00000043286.8
 Poli
polymerase (DNA directed), iota
chr1_-_64121456 0.075 ENSMUST00000142009.1
ENSMUST00000114086.1
 Klf7

Kruppel-like factor 7 (ubiquitous)

chr15_+_44428073 0.074 ENSMUST00000060652.3
 Eny2
enhancer of yellow 2 homolog (Drosophila)
chr12_-_69893162 0.045 ENSMUST00000049239.7
ENSMUST00000110570.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr11_-_35980473 0.016 ENSMUST00000018993.6
 Wwc1
WW, C2 and coiled-coil domain containing 1
chr6_+_91684061 0.013 ENSMUST00000032185.7
 Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0044838 germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.1 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism