Motif ID: Prdm4

Z-value: 0.378


Transcription factors associated with Prdm4:

Gene SymbolEntrez IDGene Name
Prdm4 ENSMUSG00000035529.9 Prdm4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prdm4mm10_v2_chr10_-_85916902_859170060.183.0e-01Click!


Activity profile for motif Prdm4.

activity profile for motif Prdm4


Sorted Z-values histogram for motif Prdm4

Sorted Z-values for motif Prdm4



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_102604370 3.056 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr1_+_74391479 1.975 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr10_+_126978690 1.338 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr10_+_26822560 1.282 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chr5_-_4758216 1.093 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr19_-_4163285 0.415 ENSMUST00000118483.1
ENSMUST00000025749.7
Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr17_+_24473884 0.401 ENSMUST00000054946.3
ENSMUST00000164508.1
Bricd5

BRICHOS domain containing 5

chr5_-_142817654 0.278 ENSMUST00000151477.1
Tnrc18
trinucleotide repeat containing 18
chr11_-_69369377 0.245 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr5_-_142817387 0.133 ENSMUST00000036253.6
Tnrc18
trinucleotide repeat containing 18
chr8_+_27042555 0.041 ENSMUST00000033875.8
ENSMUST00000098851.4
Prosc

proline synthetase co-transcribed

chr5_-_144965793 0.019 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr9_+_17030045 0.017 ENSMUST00000164523.2
Gm5611
predicted gene 5611

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0060022 hard palate development(GO:0060022)
0.1 3.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 4.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)