Motif ID: Prrx1_Isx_Prrxl1

Z-value: 0.690

Transcription factors associated with Prrx1_Isx_Prrxl1:

Gene SymbolEntrez IDGene Name
Isx ENSMUSG00000031621.3 Isx
Prrx1 ENSMUSG00000026586.10 Prrx1
Prrxl1 ENSMUSG00000041730.7 Prrxl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prrxl1mm10_v2_chr14_+_32599922_32599932-0.482.9e-03Click!
Prrx1mm10_v2_chr1_-_163313661_1633137100.473.6e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 5.077 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr14_+_80000292 2.716 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr14_-_101609033 2.379 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chrM_+_11734 2.341 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr3_+_86070915 2.274 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr9_+_118478344 2.018 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_-_160619971 1.959 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr15_-_8710734 1.932 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_118478182 1.924 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_+_116067213 1.833 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_-_62766153 1.774 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_49757257 1.648 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr4_-_87806296 1.395 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr5_-_124095749 1.344 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_+_58210397 1.319 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr15_-_8710409 1.273 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_32923455 1.221 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr15_-_37459327 1.206 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr4_-_87806276 1.180 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_163725123 1.167 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr11_-_117873433 1.159 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr18_-_66860458 1.115 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr12_+_9029982 1.102 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr9_+_80165079 1.093 ENSMUST00000184480.1
Myo6
myosin VI
chr17_+_78508063 1.032 ENSMUST00000024880.9
Vit
vitrin
chr1_-_56969864 0.992 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_33942111 0.986 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr11_+_94936224 0.967 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr9_-_42399915 0.942 ENSMUST00000042190.7
Tecta
tectorin alpha
chr9_-_42399709 0.942 ENSMUST00000160940.1
Tecta
tectorin alpha
chr2_+_91257323 0.942 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr18_+_37320374 0.869 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr18_-_78206408 0.862 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr6_-_37442095 0.831 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr8_-_105966038 0.772 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr17_+_3397189 0.772 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_24005608 0.764 ENSMUST00000027338.3
1110058L19Rik
RIKEN cDNA 1110058L19 gene
chr2_-_116067391 0.753 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr2_-_170194033 0.734 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr14_-_76010863 0.730 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chrM_+_10167 0.728 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr14_-_118052235 0.720 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr4_+_102589687 0.711 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr1_-_56969827 0.708 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chrX_+_99975570 0.700 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr4_+_5724304 0.694 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr1_-_144177259 0.671 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr18_-_39487096 0.664 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr19_-_43912392 0.664 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr18_+_69593361 0.662 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr3_+_41742615 0.661 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr8_+_121116163 0.660 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr4_-_82505749 0.655 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr11_+_53433299 0.653 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr12_-_25096080 0.649 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr11_-_59163281 0.649 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr8_+_94172618 0.643 ENSMUST00000034214.6
Mt2
metallothionein 2
chr8_-_106573461 0.632 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr4_-_82505274 0.603 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr3_+_66219909 0.596 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_91256813 0.586 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr12_-_4841583 0.577 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr13_-_105271039 0.572 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr15_+_85510812 0.567 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_+_167598450 0.561 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr19_-_19001099 0.558 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr8_-_105568298 0.551 ENSMUST00000005849.5
Agrp
agouti related protein
chr5_-_35105691 0.550 ENSMUST00000030986.8
Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr8_+_23411490 0.547 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr4_+_154964117 0.531 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr2_+_155751117 0.531 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr2_-_155945282 0.526 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr8_-_120228221 0.525 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr13_+_44121167 0.522 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr3_+_84593547 0.518 ENSMUST00000062623.3
Tigd4
tigger transposable element derived 4
chr18_+_38993126 0.517 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr3_+_89715016 0.510 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chrX_+_163911401 0.508 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_+_132610620 0.506 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr17_+_56613392 0.505 ENSMUST00000080492.5
Rpl36
ribosomal protein L36
chr18_+_60774510 0.504 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr1_+_170308802 0.494 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr18_+_60774675 0.488 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr3_-_59220150 0.480 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr7_-_46667375 0.463 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr2_-_34913976 0.460 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr17_-_36042690 0.459 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
H2-T22


histocompatibility 2, T region locus 22


chrM_+_9870 0.454 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr17_+_94873986 0.454 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr15_+_99006056 0.453 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr11_+_32000452 0.450 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2

neuron specific gene family member 2

chr5_-_62765618 0.450 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_66296807 0.446 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr1_-_24612700 0.441 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrX_+_38600626 0.440 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr17_-_45599603 0.439 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr11_+_109543694 0.431 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr7_+_140941550 0.429 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr4_-_82505707 0.424 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr7_+_45526330 0.409 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr18_-_13972617 0.406 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr2_-_71546745 0.406 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr7_-_79848191 0.401 ENSMUST00000107392.1
Anpep
alanyl (membrane) aminopeptidase
chr10_-_42583628 0.395 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr3_+_66985947 0.394 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr16_+_33684460 0.386 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr9_-_71896047 0.370 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr16_-_90810365 0.366 ENSMUST00000140920.1
Urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr6_+_17749170 0.362 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr7_-_127895578 0.361 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr1_-_158356258 0.361 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr7_+_19368498 0.353 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr11_+_35121126 0.350 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr15_+_98571004 0.337 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chrM_+_8600 0.332 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr13_+_94788873 0.332 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr10_+_41490436 0.328 ENSMUST00000105507.3
Ppil6
peptidylprolyl isomerase (cyclophilin)-like 6
chr8_+_54954728 0.327 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr18_+_37400845 0.322 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr9_+_48362034 0.320 ENSMUST00000093853.4
Nxpe4
neurexophilin and PC-esterase domain family, member 4
chr4_-_24430838 0.320 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr18_+_4375583 0.319 ENSMUST00000025077.6
Mtpap
mitochondrial poly(A) polymerase
chrX_+_159708593 0.317 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_+_167598384 0.313 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr11_-_98729374 0.311 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr10_+_99263224 0.309 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr17_-_36032682 0.301 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr8_-_69373914 0.300 ENSMUST00000095282.1
Gm10311
predicted gene 10311
chr5_+_52783055 0.300 ENSMUST00000113904.2
ENSMUST00000031077.8
Zcchc4

zinc finger, CCHC domain containing 4

chr4_-_132463873 0.298 ENSMUST00000102567.3
Med18
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr6_-_83121385 0.297 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr8_-_105484350 0.295 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr3_-_98339921 0.293 ENSMUST00000065793.5
Phgdh
3-phosphoglycerate dehydrogenase
chr2_+_20737306 0.291 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr9_-_89705017 0.290 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr9_+_119341487 0.290 ENSMUST00000175743.1
ENSMUST00000176397.1
Acaa1a

acetyl-Coenzyme A acyltransferase 1A

chr9_+_92457369 0.286 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr3_+_88579602 0.284 ENSMUST00000035785.7
Ssr2
signal sequence receptor, beta
chr13_+_96388294 0.279 ENSMUST00000099295.4
Poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr5_-_84417359 0.274 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr10_+_19951055 0.274 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr2_+_52038005 0.273 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr7_-_45526146 0.272 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chrX_+_56963325 0.264 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr2_-_177267036 0.262 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr2_-_29787622 0.256 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr8_-_46294592 0.254 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr13_-_4609122 0.249 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr3_+_122419772 0.245 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr2_-_72986716 0.244 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chrX_-_165004829 0.244 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr13_+_49504774 0.243 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chrY_+_90785442 0.242 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr18_+_75000469 0.237 ENSMUST00000079716.5
Rpl17
ribosomal protein L17
chr14_-_18893376 0.235 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr17_-_51826562 0.215 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr8_-_105637403 0.214 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr13_-_81570640 0.212 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr11_+_106751226 0.212 ENSMUST00000147326.2
ENSMUST00000182896.1
ENSMUST00000182908.1
ENSMUST00000086353.4
Milr1



mast cell immunoglobulin like receptor 1



chr3_+_66985647 0.212 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr19_+_5474681 0.211 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr9_+_119341294 0.208 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr8_+_71542911 0.207 ENSMUST00000034272.7
Mvb12a
multivesicular body subunit 12A
chr15_+_81744848 0.206 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr6_-_34317442 0.203 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr2_+_152736244 0.200 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr6_+_58831748 0.198 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr11_+_32000496 0.197 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr6_+_36388055 0.192 ENSMUST00000172278.1
Chrm2
cholinergic receptor, muscarinic 2, cardiac
chr17_+_74395607 0.192 ENSMUST00000179074.1
ENSMUST00000024870.6
Slc30a6

solute carrier family 30 (zinc transporter), member 6

chr2_-_130664565 0.190 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr2_-_34826071 0.189 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr2_-_45110336 0.187 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr10_+_79704499 0.185 ENSMUST00000067036.5
ENSMUST00000178383.1
Bsg

basigin

chr2_+_30952955 0.184 ENSMUST00000028199.5
Tor1b
torsin family 1, member B
chr19_+_8802486 0.184 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr18_+_37755718 0.184 ENSMUST00000061279.7
Pcdhga9
protocadherin gamma subfamily A, 9
chr7_+_67655414 0.183 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chrX_+_170010744 0.181 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr12_+_117843489 0.178 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr14_+_24490678 0.177 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr3_-_37125943 0.170 ENSMUST00000029275.5
Il2
interleukin 2
chr12_-_73047179 0.170 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr11_+_113684412 0.169 ENSMUST00000042227.8
ENSMUST00000123466.1
ENSMUST00000106621.3
D11Wsu47e


DNA segment, Chr 11, Wayne State University 47, expressed


chr11_+_90030295 0.168 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr7_+_19508712 0.166 ENSMUST00000002112.8
ENSMUST00000108455.1
Trappc6a

trafficking protein particle complex 6A

chr3_-_86142684 0.165 ENSMUST00000029722.6
Rps3a1
ribosomal protein S3A1
chr9_-_59353430 0.162 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr16_+_16870736 0.161 ENSMUST00000139740.1
ENSMUST00000119787.2
ENSMUST00000130650.1
ENSMUST00000156502.1
ENSMUST00000023465.7
ENSMUST00000124960.1
ENSMUST00000144513.1
Top3b






topoisomerase (DNA) III beta






chr5_+_109940426 0.160 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr17_-_37483543 0.159 ENSMUST00000016427.4
ENSMUST00000171139.2
H2-M2

histocompatibility 2, M region locus 2

chr14_+_25980039 0.159 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr4_+_115839192 0.158 ENSMUST00000019677.5
ENSMUST00000144427.1
ENSMUST00000106513.3
ENSMUST00000130819.1
ENSMUST00000151203.1
ENSMUST00000140315.1
Mknk1





MAP kinase-interacting serine/threonine kinase 1





chr3_-_57294880 0.156 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr5_-_127632897 0.156 ENSMUST00000155321.1
Slc15a4
solute carrier family 15, member 4
chr3_+_90476121 0.154 ENSMUST00000001042.8
Ilf2
interleukin enhancer binding factor 2
chr9_-_15301555 0.152 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr11_-_113684155 0.151 ENSMUST00000120194.1
Fam104a
family with sequence similarity 104, member A
chr4_+_43493345 0.150 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr1_+_24678536 0.143 ENSMUST00000095062.3
Lmbrd1
LMBR1 domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.8 3.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 1.5 GO:0006566 threonine metabolic process(GO:0006566)
0.4 1.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 2.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 1.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 3.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.7 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 1.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.2 0.7 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.6 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 3.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.7 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.6 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.5 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0060315 response to redox state(GO:0051775) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.1 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.8 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.7 GO:0002076 osteoblast development(GO:0002076)
0.1 0.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 3.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 4.9 GO:0007601 visual perception(GO:0007601)
0.1 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.2 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) protein localization to photoreceptor outer segment(GO:1903546)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.1 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.1 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 2.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.2 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:1990564 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0015817 histidine transport(GO:0015817)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.5 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0009651 response to salt stress(GO:0009651)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005584 collagen type I trimer(GO:0005584)
0.2 2.7 GO:0042581 specific granule(GO:0042581)
0.1 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 2.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.7 GO:0070469 respiratory chain(GO:0070469)
0.0 0.0 GO:0034709 methylosome(GO:0034709)
0.0 2.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 3.3 GO:0044297 cell body(GO:0044297)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.1 GO:0019841 retinol binding(GO:0019841)
0.5 3.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.2 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 1.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 1.3 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 1.3 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 0.5 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 0.7 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 0.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 3.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 2.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 4.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 4.0 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 2.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 4.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.4 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.7 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 2.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs