Motif ID: Rarg

Z-value: 1.129


Transcription factors associated with Rarg:

Gene SymbolEntrez IDGene Name
Rarg ENSMUSG00000001288.8 Rarg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rargmm10_v2_chr15_-_102257306_1022573700.529.7e-04Click!


Activity profile for motif Rarg.

activity profile for motif Rarg


Sorted Z-values histogram for motif Rarg

Sorted Z-values for motif Rarg



Network of associatons between targets according to the STRING database.



First level regulatory network of Rarg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_70501116 6.525 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr1_-_171059390 6.131 ENSMUST00000164044.1
ENSMUST00000169017.1
 Fcgr3

Fc receptor, IgG, low affinity III

chr16_+_41532999 3.849 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr9_+_27790947 3.742 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr10_+_58813359 3.700 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr5_-_113015473 3.687 ENSMUST00000065167.4
 Adrbk2
adrenergic receptor kinase, beta 2
chr14_+_101840602 3.439 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr3_+_86070915 3.188 ENSMUST00000182666.1
 Sh3d19
SH3 domain protein D19
chr2_+_14229390 3.079 ENSMUST00000028045.2
 Mrc1
mannose receptor, C type 1
chr7_-_46179929 3.065 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr19_-_57008187 2.885 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr13_-_51567084 2.813 ENSMUST00000021898.5
 Shc3
src homology 2 domain-containing transforming protein C3
chr14_+_101840501 2.746 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr12_-_54203860 2.656 ENSMUST00000039516.3
 Egln3
EGL nine homolog 3 (C. elegans)
chr2_-_25319095 2.652 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
 Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr5_-_146585239 2.637 ENSMUST00000036211.6
 Gpr12
G-protein coupled receptor 12
chr14_+_70890099 2.565 ENSMUST00000022699.8
 Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr7_+_18884679 2.559 ENSMUST00000032573.6
 Pglyrp1
peptidoglycan recognition protein 1
chr9_-_107668967 2.514 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr19_+_34217588 2.491 ENSMUST00000119603.1
 Stambpl1
STAM binding protein like 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 262 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 6.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
2.2 6.6 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.8 5.5 GO:0015862 uridine transport(GO:0015862)
0.2 4.9 GO:0035641 locomotory exploration behavior(GO:0035641)
1.6 4.8 GO:1900673 olefin metabolic process(GO:1900673)
0.7 4.5 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.5 4.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 3.3 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 3.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.0 3.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 3.1 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.4 3.0 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 2.9 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.9 2.8 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 2.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.3 2.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.9 2.6 GO:0051715 cytolysis in other organism(GO:0051715)
0.6 2.5 GO:0015817 histidine transport(GO:0015817)
0.2 2.5 GO:0016322 neuron remodeling(GO:0016322)
0.6 2.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 114 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 7.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 7.3 GO:0031225 anchored component of membrane(GO:0031225)
2.2 6.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 6.5 GO:0016324 apical plasma membrane(GO:0016324)
0.1 6.0 GO:0005604 basement membrane(GO:0005604)
1.2 4.8 GO:0044307 dendritic branch(GO:0044307)
0.2 3.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 3.5 GO:0000139 Golgi membrane(GO:0000139)
0.8 3.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 3.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 3.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.6 2.5 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 2.5 GO:0043197 dendritic spine(GO:0043197)
0.7 2.2 GO:0098855 HCN channel complex(GO:0098855)
0.5 2.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 2.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 179 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 6.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.3 6.4 GO:0019770 IgG receptor activity(GO:0019770)
0.2 6.2 GO:0042805 actinin binding(GO:0042805)
0.2 5.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.7 4.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.8 4.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 4.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.2 GO:0005518 collagen binding(GO:0005518)
0.3 4.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 3.7 GO:0005537 mannose binding(GO:0005537)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.6 3.0 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7 2.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 2.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.9 2.8 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 2.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.8 GO:0005267 potassium channel activity(GO:0005267)
0.3 2.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 2.7 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.7 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 7.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 2.2 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.2 2.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.5 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 1.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 1.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 5.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.7 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 3.4 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.4 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 3.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 3.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.2 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.1 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 2.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 2.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.2 1.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway