Motif ID: Rbpj

Z-value: 0.868


Transcription factors associated with Rbpj:

Gene SymbolEntrez IDGene Name
Rbpj ENSMUSG00000039191.6 Rbpj

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjmm10_v2_chr5_+_53590453_535905740.554.5e-04Click!


Activity profile for motif Rbpj.

activity profile for motif Rbpj


Sorted Z-values histogram for motif Rbpj

Sorted Z-values for motif Rbpj



Network of associatons between targets according to the STRING database.



First level regulatory network of Rbpj

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_11007635 4.079 ENSMUST00000054776.3
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr15_-_86033777 3.639 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_+_105668888 3.280 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr2_+_105668935 3.252 ENSMUST00000142772.1
Pax6
paired box gene 6
chr4_+_107830958 2.736 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr9_+_123478693 2.643 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chrX_+_139684980 2.472 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr11_+_101627942 2.287 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr2_+_133552159 2.044 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr7_+_126781483 1.992 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr11_-_102579461 1.963 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr4_+_8690399 1.919 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr2_+_59612034 1.904 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_-_44670820 1.658 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr7_+_45216671 1.608 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr7_+_44748584 1.601 ENSMUST00000171821.1
Vrk3
vaccinia related kinase 3
chr3_-_89270489 1.494 ENSMUST00000107460.1
ENSMUST00000029565.4
ENSMUST00000130230.1
Slc50a1


solute carrier family 50 (sugar transporter), member 1


chr7_+_44748640 1.483 ENSMUST00000165957.1
ENSMUST00000144515.2
Vrk3

vaccinia related kinase 3

chr10_-_30842765 1.466 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr11_-_62457772 1.336 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr11_+_78324200 1.320 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr7_+_16842896 1.319 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr7_+_44748413 1.283 ENSMUST00000002275.8
Vrk3
vaccinia related kinase 3
chr2_-_69586021 1.175 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr2_+_154548888 1.015 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr11_-_62457289 0.956 ENSMUST00000069456.4
ENSMUST00000018645.6
Ncor1

nuclear receptor co-repressor 1

chr5_+_138171997 0.943 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chr9_-_103222063 0.935 ENSMUST00000170904.1
Trf
transferrin
chr6_-_37299950 0.932 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr7_+_45639964 0.909 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chrX_+_58030622 0.898 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr15_-_81858317 0.859 ENSMUST00000050467.7
Tob2
transducer of ERBB2, 2
chr9_-_55512156 0.848 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr11_-_50887443 0.819 ENSMUST00000050595.6
ENSMUST00000163301.1
ENSMUST00000109131.1
ENSMUST00000125749.1
Zfp454



zinc finger protein 454



chr2_+_92184106 0.813 ENSMUST00000111294.1
ENSMUST00000111293.2
ENSMUST00000162146.1
ENSMUST00000111292.1
ENSMUST00000162497.1
Phf21a




PHD finger protein 21A




chr9_-_26806384 0.808 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2


galactosidase, beta 1-like 2


chr4_+_156203292 0.785 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chr6_+_29694204 0.782 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr7_-_105752193 0.780 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr1_-_191575534 0.779 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr15_-_75894474 0.773 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr6_+_48593883 0.771 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr3_-_103809278 0.757 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr2_-_54085542 0.754 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chrX_+_99136119 0.739 ENSMUST00000052839.6
Efnb1
ephrin B1
chr13_-_67360509 0.727 ENSMUST00000081582.6
ENSMUST00000185002.1
Zfp953
ZFP953
zinc finger protein 953
Protein Zfp953
chr7_+_122159422 0.713 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr8_-_111743799 0.713 ENSMUST00000166232.2
Bcar1
breast cancer anti-estrogen resistance 1
chr13_-_67609617 0.693 ENSMUST00000138725.1
AA987161
expressed sequence AA987161
chr7_+_29768552 0.662 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr12_+_33315393 0.660 ENSMUST00000154742.1
Atxn7l1
ataxin 7-like 1
chr8_-_69974367 0.637 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr12_+_83688123 0.629 ENSMUST00000041806.5
Psen1
presenilin 1
chr2_+_119547697 0.626 ENSMUST00000014221.6
ENSMUST00000119172.1
Chp1

calcineurin-like EF hand protein 1

chr1_+_191575721 0.623 ENSMUST00000045450.5
Ints7
integrator complex subunit 7
chr7_-_24208093 0.615 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr5_-_88675190 0.605 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr4_-_147848358 0.604 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr13_-_67484225 0.592 ENSMUST00000019572.7
Zfp874b
zinc finger protein 874b
chr7_+_29983948 0.590 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr5_-_88675613 0.588 ENSMUST00000113234.1
ENSMUST00000153565.1
Grsf1

G-rich RNA sequence binding factor 1

chr2_-_26140468 0.583 ENSMUST00000133808.1
C330006A16Rik
RIKEN cDNA C330006A16 gene
chr6_+_21949571 0.582 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr11_-_69197809 0.561 ENSMUST00000094078.3
ENSMUST00000021262.3
Alox8

arachidonate 8-lipoxygenase

chr16_+_44943737 0.560 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr12_-_14152038 0.557 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chrX_-_73966329 0.552 ENSMUST00000114372.2
ENSMUST00000033761.6
Hcfc1

host cell factor C1

chr1_+_97770158 0.550 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr15_-_55072139 0.539 ENSMUST00000041733.7
Taf2
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr12_+_31265279 0.538 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr12_-_4477138 0.515 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr14_-_56571830 0.484 ENSMUST00000065302.7
Cenpj
centromere protein J
chr1_+_87327044 0.459 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr2_+_164403194 0.459 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr13_+_12395362 0.441 ENSMUST00000059270.8
Heatr1
HEAT repeat containing 1
chr5_+_130257029 0.435 ENSMUST00000100662.3
ENSMUST00000040213.6
Tyw1

tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

chr12_+_82170016 0.434 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr9_+_35559460 0.434 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr5_-_75978447 0.431 ENSMUST00000113516.1
Kdr
kinase insert domain protein receptor
chr15_+_83563571 0.421 ENSMUST00000047419.6
Tspo
translocator protein
chr1_+_74153981 0.414 ENSMUST00000027372.7
ENSMUST00000106899.2
Cxcr2

chemokine (C-X-C motif) receptor 2

chr7_+_79273201 0.413 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr16_+_11322915 0.412 ENSMUST00000115814.3
Snx29
sorting nexin 29
chr5_+_138187485 0.408 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr19_+_7297658 0.401 ENSMUST00000170286.1
Gm17227
predicted gene 17227
chrX_+_42149288 0.393 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr11_+_54314960 0.383 ENSMUST00000064690.3
ENSMUST00000108899.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr3_-_131344892 0.373 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chr7_+_127777376 0.368 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chr12_+_31265234 0.364 ENSMUST00000169088.1
Lamb1
laminin B1
chr9_+_64811313 0.364 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr2_-_120609500 0.364 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr15_+_6708372 0.355 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr3_+_146220955 0.355 ENSMUST00000039164.2
Lpar3
lysophosphatidic acid receptor 3
chr7_+_5020561 0.349 ENSMUST00000085427.3
Zfp865
zinc finger protein 865
chr9_-_114640175 0.344 ENSMUST00000070117.6
Cnot10
CCR4-NOT transcription complex, subunit 10
chr7_+_30095150 0.336 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chrX_-_160138375 0.319 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr10_+_80299084 0.316 ENSMUST00000154212.1
Apc2
adenomatosis polyposis coli 2
chr13_-_67451585 0.312 ENSMUST00000057241.8
ENSMUST00000075255.5
Zfp874a

zinc finger protein 874a

chr9_-_66795331 0.308 ENSMUST00000113730.2
Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr9_+_106821874 0.308 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr2_-_120609283 0.305 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr2_+_164746028 0.301 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr4_-_126202583 0.301 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr5_+_3543812 0.299 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr1_+_150393250 0.299 ENSMUST00000119161.2
Tpr
translocated promoter region
chr2_-_120609319 0.298 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr2_+_164745979 0.289 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr6_-_5298455 0.282 ENSMUST00000057792.8
Pon2
paraoxonase 2
chr5_-_138172383 0.270 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_+_120404757 0.267 ENSMUST00000135074.1
Ganc
glucosidase, alpha; neutral C
chr7_+_5015466 0.265 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr5_+_33658550 0.259 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr18_-_37935403 0.254 ENSMUST00000080033.6
ENSMUST00000115631.1
Diap1

diaphanous homolog 1 (Drosophila)

chr13_-_67609667 0.253 ENSMUST00000012873.8
AA987161
expressed sequence AA987161
chr6_+_117841258 0.248 ENSMUST00000136889.1
ENSMUST00000134526.1
ENSMUST00000112860.1
ENSMUST00000112858.1
Zfp637



zinc finger protein 637



chr2_-_119547627 0.247 ENSMUST00000060009.2
Exd1
exonuclease 3'-5' domain containing 1
chr4_-_156197479 0.244 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr1_+_87327008 0.243 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr7_+_29816061 0.231 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr2_+_37776229 0.227 ENSMUST00000050372.7
Crb2
crumbs homolog 2 (Drosophila)
chr1_+_20951666 0.217 ENSMUST00000038447.4
Efhc1
EF-hand domain (C-terminal) containing 1
chr5_-_138171813 0.209 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr18_-_37935378 0.207 ENSMUST00000025337.7
Diap1
diaphanous homolog 1 (Drosophila)
chr3_+_103809520 0.207 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
Ap4b1



adaptor-related protein complex AP-4, beta 1



chr14_-_78536854 0.203 ENSMUST00000022593.5
Akap11
A kinase (PRKA) anchor protein 11
chr16_-_17722879 0.197 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr18_-_37935429 0.194 ENSMUST00000115634.1
Diap1
diaphanous homolog 1 (Drosophila)
chr7_+_5020376 0.189 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr16_-_75766758 0.186 ENSMUST00000114244.1
ENSMUST00000046283.8
Hspa13

heat shock protein 70 family, member 13

chr2_-_167062607 0.182 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chrX_+_100494291 0.169 ENSMUST00000033570.5
Igbp1
immunoglobulin (CD79A) binding protein 1
chr19_-_6992478 0.168 ENSMUST00000025915.5
Dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr5_+_148959263 0.166 ENSMUST00000135240.1
Gm15409
predicted gene 15409
chr2_+_120609383 0.165 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr7_-_29853611 0.157 ENSMUST00000085792.4
ENSMUST00000108223.1
Zfp940

zinc finger protein 940

chr14_-_78536762 0.156 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chr9_-_13446753 0.152 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chr4_+_116995306 0.152 ENSMUST00000050067.9
Hectd3
HECT domain containing 3
chr8_+_110721462 0.148 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chrX_+_94234921 0.144 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr13_+_67813740 0.144 ENSMUST00000181391.1
ENSMUST00000012725.7
Zfp273

zinc finger protein 273

chr13_-_67306412 0.141 ENSMUST00000049705.7
Zfp457
zinc finger protein 457
chr17_+_34205100 0.136 ENSMUST00000131105.1
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_29313227 0.128 ENSMUST00000161605.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr8_+_22060712 0.117 ENSMUST00000072572.6
ENSMUST00000110737.2
ENSMUST00000131624.1
Alg11


asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)


chr3_+_7612702 0.114 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr12_-_36382181 0.114 ENSMUST00000171007.1
D630036H23Rik
RIKEN cDNA D630036H23 gene
chr7_-_44748306 0.113 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr13_+_21478907 0.112 ENSMUST00000062609.5
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr16_+_22009471 0.112 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr4_-_149166686 0.109 ENSMUST00000084124.6
Pgd
phosphogluconate dehydrogenase
chr14_-_66124482 0.107 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr6_+_117841174 0.101 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
Zfp637




zinc finger protein 637




chr5_+_135994796 0.094 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr4_-_117914968 0.091 ENSMUST00000036156.5
Ipo13
importin 13
chr1_+_87326997 0.090 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr18_+_37736897 0.088 ENSMUST00000091935.4
Pcdhga9
protocadherin gamma subfamily A, 9
chr1_-_150393024 0.072 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331

cDNA sequence BC003331

chr3_+_131564768 0.069 ENSMUST00000029666.9
Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr5_-_106696819 0.063 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr13_-_67332525 0.032 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr3_+_61364507 0.027 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr19_+_53140430 0.022 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr12_+_8973892 0.017 ENSMUST00000085745.6
ENSMUST00000111113.2
Wdr35

WD repeat domain 35

chr13_+_73604002 0.015 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr10_-_93889609 0.007 ENSMUST00000180375.1
Metap2
methionine aminopeptidase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.2 3.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7 1.5 GO:0003195 tricuspid valve formation(GO:0003195)
0.7 2.0 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.6 1.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 2.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.4 2.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 2.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 2.0 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 4.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.7 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 0.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.7 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.2 0.6 GO:0019046 release from viral latency(GO:0019046)
0.2 0.7 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.5 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.6 GO:0015871 astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871)
0.1 0.9 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 1.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.1 GO:1900673 olefin metabolic process(GO:1900673)
0.1 0.4 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.3 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 0.9 GO:0046959 habituation(GO:0046959)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.2 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 1.2 GO:0045056 transcytosis(GO:0045056)
0.1 1.9 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 1.6 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.7 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.7 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0002489 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.0 0.8 GO:0001967 suckling behavior(GO:0001967)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.9 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 2.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.8 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.8 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.7 GO:0097513 myosin II filament(GO:0097513)
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.8 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 2.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 3.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.9 GO:0097433 dense body(GO:0097433)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.4 GO:0097443 sorting endosome(GO:0097443)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 6.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0038025 reelin receptor activity(GO:0038025)
0.5 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.4 6.5 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.3 2.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 2.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.5 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.2 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 0.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.6 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.5 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 4.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 3.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0042562 hormone binding(GO:0042562)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 2.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 7.2 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.9 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 0.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 2.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.7 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 2.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation