Motif ID: Rela_Rel_Nfkb1

Z-value: 1.914

Transcription factors associated with Rela_Rel_Nfkb1:

Gene SymbolEntrez IDGene Name
Nfkb1 ENSMUSG00000028163.11 Nfkb1
Rel ENSMUSG00000020275.8 Rel
Rela ENSMUSG00000024927.7 Rela

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb1mm10_v2_chr3_-_135608221_1356082900.572.3e-04Click!
Relamm10_v2_chr19_+_5637475_56374860.289.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_74791516 22.344 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr1_+_64532790 13.889 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
Creb1


cAMP responsive element binding protein 1


chr2_-_165234689 13.211 ENSMUST00000065438.6
Cdh22
cadherin 22
chr8_-_61902669 12.867 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr6_-_48840988 11.356 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr6_-_48841098 11.248 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr6_-_48841373 10.890 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr6_+_48841476 10.002 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_48841633 9.852 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr1_+_185454803 8.526 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr5_+_92925400 8.288 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr6_+_4755327 7.515 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr17_-_35000848 7.510 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr9_-_119093468 7.165 ENSMUST00000010804.2
Plcd1
phospholipase C, delta 1
chr2_-_151973387 7.136 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr17_-_35702040 7.048 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr7_-_103843154 6.844 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr17_-_35701937 6.697 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr2_-_151973840 6.384 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr7_-_102250086 6.290 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr12_+_79029150 6.216 ENSMUST00000039928.5
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr11_+_101176041 6.022 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr19_-_58454580 6.002 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr11_-_54962903 5.961 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr17_-_35702297 5.727 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chr17_-_35000746 5.682 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr19_-_58455161 5.623 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_-_19015347 5.552 ENSMUST00000019997.4
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr7_+_75455534 5.503 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr3_-_116424007 5.425 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr19_-_58454435 5.336 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr4_-_135272798 5.294 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr3_-_116423930 5.197 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr8_+_90828820 5.181 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr4_-_91399984 5.177 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_72491939 5.159 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr5_-_106458440 5.123 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr8_+_70863127 5.112 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr11_-_70656467 4.974 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr5_+_53590453 4.945 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_52699297 4.761 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr13_+_51846673 4.549 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr1_-_82291370 4.535 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr1_+_171250416 4.462 ENSMUST00000111315.1
ENSMUST00000006570.5
Adamts4

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4

chr5_+_53590215 4.444 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr9_+_54764748 4.438 ENSMUST00000034830.8
Crabp1
cellular retinoic acid binding protein I
chr4_+_80910646 4.431 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr8_+_46739745 4.415 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr3_-_65958236 4.413 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr1_+_109983006 4.405 ENSMUST00000145188.1
Cdh7
cadherin 7, type 2
chr3_-_101836223 4.401 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr2_+_105682463 4.244 ENSMUST00000140173.1
ENSMUST00000135412.1
ENSMUST00000138365.1
ENSMUST00000145744.1
Pax6



paired box gene 6



chr6_+_8948608 4.238 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr2_-_37422869 4.205 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr11_+_78301529 4.125 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr13_+_33964659 4.107 ENSMUST00000021843.5
ENSMUST00000058978.7
Nqo2

NAD(P)H dehydrogenase, quinone 2

chr14_-_30607808 4.066 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr7_-_44815658 4.039 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr14_-_37098211 3.954 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr6_+_83135812 3.954 ENSMUST00000065512.4
Rtkn
rhotekin
chr4_-_42168603 3.954 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr13_+_42052015 3.858 ENSMUST00000060148.5
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr17_+_43667389 3.812 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr7_-_25788635 3.761 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr11_+_94211431 3.744 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr15_-_89170688 3.720 ENSMUST00000060808.9
Plxnb2
plexin B2
chr2_-_181459364 3.713 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr18_+_4994600 3.709 ENSMUST00000140448.1
Svil
supervillin
chr1_-_5019342 3.650 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr6_+_134035691 3.610 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr17_-_23745829 3.605 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2
chr1_+_109982710 3.604 ENSMUST00000112701.1
Cdh7
cadherin 7, type 2
chr13_+_44730726 3.529 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr19_+_45015198 3.520 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr1_-_134079114 3.505 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr9_+_91368970 3.481 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr6_+_125096145 3.470 ENSMUST00000112390.1
Chd4
chromodomain helicase DNA binding protein 4
chr19_+_46304709 3.449 ENSMUST00000073116.5
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr5_+_33658123 3.443 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr3_+_7612702 3.394 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr10_+_25359798 3.390 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr2_-_26294550 3.352 ENSMUST00000057224.3
4932418E24Rik
RIKEN cDNA 4932418E24 gene
chr2_+_144556229 3.346 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)


chr3_+_40800054 3.344 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr3_+_40800013 3.339 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr10_-_49788743 3.326 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr7_-_142899985 3.294 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr9_-_14614949 3.288 ENSMUST00000013220.6
ENSMUST00000160770.1
Amotl1

angiomotin-like 1

chr3_-_135691512 3.240 ENSMUST00000029812.7
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr2_+_124089961 3.216 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr9_+_65265173 3.188 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_-_172590463 3.167 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr9_+_91368811 3.164 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr6_+_34354119 3.145 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr19_+_45015168 3.095 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr4_+_100776664 3.018 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr5_+_92683625 2.967 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr2_-_118549668 2.927 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chr4_+_128755364 2.916 ENSMUST00000106077.1
A3galt2
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr2_+_144556306 2.901 ENSMUST00000155876.1
ENSMUST00000149697.1
Sec23b

SEC23B (S. cerevisiae)

chr5_+_114568016 2.878 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr2_+_13573927 2.855 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr6_+_42350000 2.851 ENSMUST00000164375.1
Zyx
zyxin
chr5_-_137116177 2.835 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr12_+_111166485 2.808 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr16_+_32914094 2.806 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr6_+_42349826 2.767 ENSMUST00000070635.6
Zyx
zyxin
chr19_+_46305682 2.758 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr17_-_56005566 2.746 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr9_+_60794468 2.742 ENSMUST00000050183.6
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_11704439 2.740 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr14_+_120275669 2.734 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr2_+_61578549 2.666 ENSMUST00000112502.1
ENSMUST00000078074.2
Tank

TRAF family member-associated Nf-kappa B activator

chr15_-_75747922 2.661 ENSMUST00000062002.4
Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chrX_-_74246364 2.649 ENSMUST00000130007.1
Flna
filamin, alpha
chrX_+_7657260 2.646 ENSMUST00000033485.7
Prickle3
prickle homolog 3 (Drosophila)
chr7_+_45017953 2.630 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr9_-_22389113 2.600 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr14_+_52016849 2.557 ENSMUST00000100638.2
Tmem253
transmembrane protein 253
chr14_-_70642268 2.552 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr7_+_79500081 2.533 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr1_-_155972887 2.532 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr10_+_7725997 2.508 ENSMUST00000019929.6
ENSMUST00000165806.1
Katna1

katanin p60 (ATPase-containing) subunit A1

chr11_-_69580230 2.507 ENSMUST00000132548.1
Wrap53
WD repeat containing, antisense to Trp53
chr17_-_31277327 2.496 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr9_-_32344237 2.455 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr12_-_84194007 2.434 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr17_-_70851189 2.420 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr5_+_30105161 2.411 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr5_-_30105359 2.368 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr2_+_156840077 2.362 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr6_-_90810118 2.336 ENSMUST00000101151.3
Iqsec1
IQ motif and Sec7 domain 1
chr19_-_40271506 2.317 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr2_-_121235689 2.308 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr12_-_91746020 2.267 ENSMUST00000166967.1
Ston2
stonin 2
chr2_-_60881360 2.249 ENSMUST00000164147.1
ENSMUST00000112509.1
Rbms1

RNA binding motif, single stranded interacting protein 1

chr2_-_84743655 2.236 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr10_+_58394381 2.233 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_25681158 2.233 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr3_+_89229046 2.225 ENSMUST00000041142.3
Muc1
mucin 1, transmembrane
chr15_+_99717515 2.222 ENSMUST00000023760.6
ENSMUST00000162194.1
Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr4_+_129820198 2.167 ENSMUST00000030578.7
Ptp4a2
protein tyrosine phosphatase 4a2
chr4_-_108071327 2.146 ENSMUST00000106701.1
Scp2
sterol carrier protein 2, liver
chr11_-_115813621 2.138 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr16_-_33056174 2.112 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chr10_-_127751707 2.085 ENSMUST00000079692.5
Gpr182
G protein-coupled receptor 182
chr10_+_58394361 2.078 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr16_-_11176056 2.058 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a

zinc finger CCCH type containing 7 A

chr13_+_113035111 2.058 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr9_-_75409951 2.053 ENSMUST00000049355.10
Mapk6
mitogen-activated protein kinase 6
chr6_-_5256226 2.045 ENSMUST00000125686.1
ENSMUST00000031773.2
Pon3

paraoxonase 3

chr9_-_102626095 2.039 ENSMUST00000093791.3
Cep63
centrosomal protein 63
chr10_-_127522428 2.025 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_-_54956047 2.004 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
Tnip1


TNFAIP3 interacting protein 1


chr14_+_69029289 1.965 ENSMUST00000014957.8
Stc1
stanniocalcin 1
chr8_-_25201349 1.943 ENSMUST00000084512.4
ENSMUST00000084030.4
Tacc1

transforming, acidic coiled-coil containing protein 1

chr11_+_114727384 1.928 ENSMUST00000069325.7
Dnaic2
dynein, axonemal, intermediate chain 2
chr9_+_64117147 1.894 ENSMUST00000034969.7
Lctl
lactase-like
chr2_+_120567687 1.881 ENSMUST00000028743.3
ENSMUST00000116437.1
ENSMUST00000153580.1
ENSMUST00000142278.1
Snap23



synaptosomal-associated protein 23



chrX_+_7762652 1.869 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
Tfe3



transcription factor E3



chr3_+_86224665 1.827 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr4_-_24430838 1.827 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr3_+_103279293 1.808 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr10_+_111506286 1.800 ENSMUST00000164773.1
Phlda1
pleckstrin homology-like domain, family A, member 1
chr19_+_5740885 1.763 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr14_+_31019183 1.763 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr2_+_69861562 1.739 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr11_-_51756378 1.730 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr2_+_103073669 1.725 ENSMUST00000011055.6
Apip
APAF1 interacting protein
chr10_+_128790903 1.723 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr12_+_111166413 1.716 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr14_-_30626196 1.710 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr10_+_7681197 1.707 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr2_+_120567652 1.706 ENSMUST00000110711.2
Snap23
synaptosomal-associated protein 23
chr11_-_104550460 1.662 ENSMUST00000106961.1
ENSMUST00000093923.2
Cdc27

cell division cycle 27

chr4_+_116221689 1.658 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr1_+_82316452 1.656 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr10_-_127288851 1.652 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr6_-_24664960 1.650 ENSMUST00000041737.7
ENSMUST00000031695.8
Wasl

Wiskott-Aldrich syndrome-like (human)

chr2_+_145785980 1.645 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chrX_-_74246534 1.631 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr12_+_111166349 1.625 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr17_+_31057686 1.598 ENSMUST00000024829.6
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr4_+_86748526 1.593 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr4_-_135971894 1.590 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr17_+_56005672 1.585 ENSMUST00000133998.1
Mpnd
MPN domain containing
chr9_-_117252450 1.578 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr12_+_111166536 1.575 ENSMUST00000060274.6
Traf3
TNF receptor-associated factor 3
chr10_-_49783259 1.572 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chrX_+_137049586 1.549 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr1_-_136230289 1.526 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr12_+_104214538 1.522 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
Serpina3f


serine (or cysteine) peptidase inhibitor, clade A, member 3F


chr4_+_43059028 1.517 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr10_-_7780866 1.503 ENSMUST00000124838.1
ENSMUST00000039763.7
Ginm1

glycoprotein integral membrane 1

chr11_+_101316917 1.503 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr4_-_133756769 1.501 ENSMUST00000008024.6
Arid1a
AT rich interactive domain 1A (SWI-like)
chr10_-_120899067 1.500 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr3_+_153973436 1.491 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr9_-_103480328 1.486 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr1_+_75450699 1.485 ENSMUST00000037708.9
Asic4
acid-sensing (proton-gated) ion channel family member 4

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 57.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
4.6 13.9 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
3.1 9.4 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
2.8 8.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
2.5 7.6 GO:0016115 terpenoid catabolic process(GO:0016115)
2.1 6.2 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
1.9 22.3 GO:0048733 sebaceous gland development(GO:0048733)
1.6 19.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.5 6.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.5 8.8 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
1.4 11.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.4 7.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
1.4 4.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.4 6.8 GO:0015671 oxygen transport(GO:0015671)
1.3 4.0 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.3 3.8 GO:0097350 neutrophil clearance(GO:0097350)
1.2 8.7 GO:0098535 de novo centriole assembly(GO:0098535)
1.2 3.7 GO:0006116 NADH oxidation(GO:0006116)
1.2 2.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.2 4.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.2 5.8 GO:0006680 glucosylceramide catabolic process(GO:0006680)
1.0 4.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
1.0 10.1 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
1.0 1.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
1.0 3.9 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.9 2.6 GO:1904170 regulation of bleb assembly(GO:1904170)
0.9 4.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.9 7.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 13.6 GO:0003334 keratinocyte development(GO:0003334)
0.8 3.3 GO:0042414 epinephrine metabolic process(GO:0042414)
0.8 3.2 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.8 1.6 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.8 3.2 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.8 3.1 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.7 2.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.6 4.4 GO:0007296 vitellogenesis(GO:0007296)
0.6 5.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.6 3.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.6 1.8 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.6 2.9 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.6 1.7 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.6 1.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.5 2.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.5 4.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.5 2.0 GO:0006545 glycine biosynthetic process(GO:0006545)
0.5 2.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.5 1.5 GO:0090403 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) oxidative stress-induced premature senescence(GO:0090403)
0.5 3.5 GO:0072553 terminal button organization(GO:0072553)
0.5 1.4 GO:0060023 soft palate development(GO:0060023)
0.5 6.2 GO:0002467 germinal center formation(GO:0002467)
0.5 1.4 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.5 4.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.5 4.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.5 1.4 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.5 7.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.4 4.9 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 4.4 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.4 1.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.4 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.4 2.5 GO:0051013 microtubule severing(GO:0051013)
0.4 8.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 5.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 1.2 GO:0090135 actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275)
0.4 5.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 3.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 1.5 GO:0030091 protein repair(GO:0030091)
0.4 1.1 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4 1.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.4 1.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 1.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 2.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 1.4 GO:0006547 histidine metabolic process(GO:0006547)
0.3 1.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 2.9 GO:0048102 autophagic cell death(GO:0048102)
0.3 2.9 GO:0030259 lipid glycosylation(GO:0030259)
0.3 1.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 0.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.3 1.8 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.3 0.9 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 1.1 GO:0072362 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.3 1.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 3.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.6 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 1.0 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943)
0.3 4.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.3 4.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.2 GO:0032329 serine transport(GO:0032329)
0.2 1.0 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.2 0.7 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.2 1.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 6.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 1.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 0.7 GO:0030321 transepithelial chloride transport(GO:0030321) transepithelial ammonium transport(GO:0070634)
0.2 1.1 GO:0040009 regulation of growth rate(GO:0040009)
0.2 1.0 GO:1990839 response to endothelin(GO:1990839)
0.2 1.0 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.2 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.2 2.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.2 10.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.2 1.5 GO:0048625 embryonic hindgut morphogenesis(GO:0048619) myoblast fate commitment(GO:0048625)
0.2 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 3.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2 1.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 3.1 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.2 1.5 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 1.5 GO:0070307 lens fiber cell development(GO:0070307)
0.2 2.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 1.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 0.5 GO:2000109 macrophage apoptotic process(GO:0071888) regulation of macrophage apoptotic process(GO:2000109) negative regulation of macrophage apoptotic process(GO:2000110)
0.2 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 2.8 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.2 11.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.7 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 3.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 4.3 GO:0001709 cell fate determination(GO:0001709)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 3.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 2.0 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 1.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.5 GO:1905076 regulation of interleukin-17 secretion(GO:1905076) positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 7.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 2.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.5 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 3.0 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 0.4 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.9 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.5 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.9 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 2.2 GO:0001967 suckling behavior(GO:0001967)
0.1 0.7 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.0 GO:0034453 microtubule anchoring(GO:0034453)
0.1 2.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0032621 interleukin-18 production(GO:0032621)
0.1 4.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 3.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 3.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.1 GO:0071864 positive regulation of cell proliferation in bone marrow(GO:0071864)
0.1 0.8 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 0.6 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.3 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 0.9 GO:0003338 metanephros morphogenesis(GO:0003338)
0.1 0.2 GO:0090282 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.1 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.9 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 4.5 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.4 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 4.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.9 GO:0006959 humoral immune response(GO:0006959)
0.0 0.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 5.9 GO:0001822 kidney development(GO:0001822)
0.0 1.9 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 2.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.1 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.0 0.1 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:0048538 thymus development(GO:0048538)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.0 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0070633 transepithelial transport(GO:0070633)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 1.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.5 4.5 GO:0005899 insulin receptor complex(GO:0005899)
1.2 8.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 6.7 GO:0098536 deuterosome(GO:0098536)
1.1 3.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.9 4.3 GO:0031523 Myb complex(GO:0031523)
0.9 6.8 GO:0005833 hemoglobin complex(GO:0005833)
0.8 4.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.7 2.9 GO:0045098 type III intermediate filament(GO:0045098)
0.7 2.7 GO:0043293 apoptosome(GO:0043293)
0.5 7.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 2.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 2.0 GO:0070552 BRISC complex(GO:0070552)
0.5 6.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.5 2.8 GO:0044305 calyx of Held(GO:0044305)
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 4.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 1.5 GO:0008537 proteasome activator complex(GO:0008537)
0.4 1.1 GO:0031251 PAN complex(GO:0031251)
0.3 15.3 GO:0002102 podosome(GO:0002102)
0.3 2.5 GO:0001520 outer dense fiber(GO:0001520)
0.3 3.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 4.8 GO:0005640 nuclear outer membrane(GO:0005640) sarcoplasmic reticulum membrane(GO:0033017)
0.3 11.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 2.3 GO:0002177 manchette(GO:0002177)
0.2 2.0 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.1 GO:0032389 MutLalpha complex(GO:0032389)
0.2 1.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.7 GO:0030478 actin cap(GO:0030478)
0.2 3.6 GO:0010369 chromocenter(GO:0010369)
0.2 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 3.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.2 2.7 GO:0051233 spindle midzone(GO:0051233)
0.2 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.2 0.9 GO:1990246 uniplex complex(GO:1990246)
0.2 3.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 5.8 GO:0090544 BAF-type complex(GO:0090544)
0.2 0.5 GO:0001740 Barr body(GO:0001740)
0.2 1.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 3.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 18.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 2.2 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 4.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.0 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 4.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 11.4 GO:0000922 spindle pole(GO:0000922)
0.1 1.2 GO:0045095 keratin filament(GO:0045095)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 4.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 2.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 6.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.1 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0001741 XY body(GO:0001741)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.2 GO:0042827 platelet dense granule(GO:0042827)
0.1 7.7 GO:0043296 apical junction complex(GO:0043296)
0.1 5.5 GO:0030496 midbody(GO:0030496)
0.1 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.4 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 13.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 3.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 4.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 2.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 7.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 9.5 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.8 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
2.2 19.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.7 6.8 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.4 5.8 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
1.1 4.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.0 4.1 GO:1990254 keratin filament binding(GO:1990254)
0.9 2.8 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.9 2.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8 5.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.8 4.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 2.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.7 4.4 GO:0019841 retinol binding(GO:0019841)
0.7 4.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.7 2.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.7 2.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.7 3.3 GO:0035240 dopamine binding(GO:0035240)
0.6 7.7 GO:0031996 thioesterase binding(GO:0031996)
0.6 3.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6 23.0 GO:0005109 frizzled binding(GO:0005109)
0.6 5.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.5 1.6 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.5 2.0 GO:0004064 arylesterase activity(GO:0004064)
0.5 4.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 2.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 2.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.5 3.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 1.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.5 1.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 1.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 4.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 4.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 1.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.4 3.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 8.5 GO:0070410 co-SMAD binding(GO:0070410)
0.4 7.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 2.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 1.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.4 2.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 14.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 3.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 4.8 GO:0043495 protein anchor(GO:0043495)
0.3 2.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 8.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 3.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 1.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.3 1.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 0.7 GO:0097677 STAT family protein binding(GO:0097677)
0.2 3.6 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 3.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.1 GO:0000405 bubble DNA binding(GO:0000405)
0.2 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 10.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.5 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 3.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 7.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.9 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 1.6 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 2.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 15.2 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 4.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 2.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 1.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 1.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.3 GO:0032356 oxidized DNA binding(GO:0032356)
0.1 4.5 GO:0004386 helicase activity(GO:0004386)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.7 GO:0019003 GDP binding(GO:0019003)
0.1 1.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 3.2 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 13.2 GO:0051015 actin filament binding(GO:0051015)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.0 GO:0030553 cGMP binding(GO:0030553)
0.1 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.9 GO:0005272 sodium channel activity(GO:0005272)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 3.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 19.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 15.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 3.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0046790 complement component C1q binding(GO:0001849) virion binding(GO:0046790)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 2.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 20.2 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 19.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.3 2.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 14.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.3 6.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.3 5.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.2 8.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 20.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.2 7.2 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 11.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.2 0.8 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 5.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 9.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.1 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 8.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 4.5 PID_CDC42_PATHWAY CDC42 signaling events
0.1 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.7 PID_BCR_5PATHWAY BCR signaling pathway
0.1 0.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 5.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 2.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.0 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 4.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST_ADRENERGIC Adrenergic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 13.5 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.7 4.9 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.6 13.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 7.6 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 8.6 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 6.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 4.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 15.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.3 5.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.3 4.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 3.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.3 2.6 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 8.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 5.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.2 2.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 19.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.6 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 1.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 7.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.2 2.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 5.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 7.9 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.2 4.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 3.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.9 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 8.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 7.7 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.3 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.5 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.2 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.2 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 2.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 2.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 3.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 0.6 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.6 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production