Motif ID: Rfx2_Rfx7

Z-value: 1.076

Transcription factors associated with Rfx2_Rfx7:

Gene SymbolEntrez IDGene Name
Rfx2 ENSMUSG00000024206.8 Rfx2
Rfx7 ENSMUSG00000037674.9 Rfx7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx2mm10_v2_chr17_-_56830916_568310080.048.0e-01Click!
Rfx7mm10_v2_chr9_+_72532214_725322710.019.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx2_Rfx7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_128953303 5.446 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr8_+_94772009 4.088 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr12_-_40038025 3.825 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr4_+_129960760 3.812 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chrX_+_52791179 3.688 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr8_+_39005880 3.393 ENSMUST00000169034.1
Tusc3
tumor suppressor candidate 3
chr5_+_27261916 3.296 ENSMUST00000101471.3
Dpp6
dipeptidylpeptidase 6
chr7_-_31051431 3.201 ENSMUST00000073892.4
Fxyd7
FXYD domain-containing ion transport regulator 7
chr8_+_39005827 3.158 ENSMUST00000167992.1
Tusc3
tumor suppressor candidate 3
chr2_-_28466266 2.960 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr18_+_75820174 2.881 ENSMUST00000058997.7
Zbtb7c
zinc finger and BTB domain containing 7C
chr7_+_16959714 2.565 ENSMUST00000038163.6
Pnmal1
PNMA-like 1
chr14_-_37098211 2.459 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr2_-_21205342 2.412 ENSMUST00000027992.2
Enkur
enkurin, TRPC channel interacting protein
chr13_+_83504032 2.287 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr5_+_30281377 2.281 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr13_+_112993868 2.220 ENSMUST00000092089.4
Mcidas
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr7_+_4922251 2.152 ENSMUST00000047309.5
Nat14
N-acetyltransferase 14
chr11_-_77725281 2.087 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr11_+_100545607 2.004 ENSMUST00000092684.5
ENSMUST00000006976.7
Ttc25

tetratricopeptide repeat domain 25

chr11_-_97041395 1.908 ENSMUST00000021251.6
Lrrc46
leucine rich repeat containing 46
chr1_+_85928483 1.694 ENSMUST00000027426.4
4933407L21Rik
RIKEN cDNA 4933407L21 gene
chr4_-_119415494 1.678 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr2_+_19199266 1.667 ENSMUST00000114640.2
ENSMUST00000049255.6
Armc3

armadillo repeat containing 3

chr15_-_79834323 1.665 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr12_+_105336922 1.648 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr15_+_89532816 1.627 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr3_-_50443603 1.617 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr16_+_52031549 1.537 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr11_-_58801944 1.465 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr2_-_118703963 1.441 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr13_-_3918157 1.417 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr12_+_111166485 1.395 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr8_+_36993551 1.387 ENSMUST00000098825.3
AI429214
expressed sequence AI429214
chr1_-_16093286 1.386 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr4_+_117096049 1.373 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr4_-_35845204 1.334 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr7_-_120982260 1.333 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr13_-_49309217 1.330 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr19_-_23652780 1.321 ENSMUST00000035849.3
1700028P14Rik
RIKEN cDNA 1700028P14 gene
chr11_+_103649498 1.320 ENSMUST00000057870.2
Rprml
reprimo-like
chr12_+_33394854 1.294 ENSMUST00000020878.6
Efcab10
EF-hand calcium binding domain 10
chr15_+_98167806 1.285 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr6_+_137252297 1.278 ENSMUST00000077115.6
ENSMUST00000167679.1
Ptpro

protein tyrosine phosphatase, receptor type, O

chr7_-_4546567 1.278 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr11_+_119229092 1.267 ENSMUST00000053440.7
Ccdc40
coiled-coil domain containing 40
chr9_+_49102720 1.260 ENSMUST00000070390.5
ENSMUST00000167095.1
Tmprss5

transmembrane protease, serine 5 (spinesin)

chr11_+_119942763 1.250 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr6_-_92706145 1.246 ENSMUST00000032093.5
Prickle2
prickle homolog 2 (Drosophila)
chr10_+_111473186 1.243 ENSMUST00000065917.8
Nap1l1
nucleosome assembly protein 1-like 1
chr11_+_117115195 1.210 ENSMUST00000103026.3
ENSMUST00000090433.5
Sec14l1

SEC14-like 1 (S. cerevisiae)

chr3_+_82358056 1.201 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr5_-_44799643 1.195 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr4_+_123183456 1.186 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr2_-_151980135 1.160 ENSMUST00000062047.5
Fam110a
family with sequence similarity 110, member A
chr11_-_23633621 1.138 ENSMUST00000180260.1
ENSMUST00000141353.1
ENSMUST00000131612.1
ENSMUST00000109532.2
0610010F05Rik



RIKEN cDNA 0610010F05 gene



chr7_+_90426312 1.127 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr13_+_119690462 1.125 ENSMUST00000179869.1
Hmgcs1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr13_-_49320219 1.092 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr12_+_112808914 1.069 ENSMUST00000037014.3
ENSMUST00000177808.1
BC022687

cDNA sequence BC022687

chr2_-_152831665 1.061 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr13_+_13784278 1.060 ENSMUST00000021734.7
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr10_+_77864623 1.048 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr12_+_111166413 1.048 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr12_-_110840905 1.037 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
Stk30


serine/threonine kinase 30


chr11_-_7213897 1.035 ENSMUST00000020702.4
ENSMUST00000135887.2
Igfbp3

insulin-like growth factor binding protein 3

chr12_-_84148449 1.028 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr14_-_55671873 1.028 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr12_+_111166349 1.013 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr19_+_47178820 1.004 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr8_+_116504973 1.002 ENSMUST00000078170.5
Dynlrb2
dynein light chain roadblock-type 2
chr17_-_10840285 0.982 ENSMUST00000041463.6
Pacrg
PARK2 co-regulated
chr7_+_16944645 0.971 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chrX_-_17319316 0.967 ENSMUST00000026014.7
Efhc2
EF-hand domain (C-terminal) containing 2
chr8_-_116978908 0.958 ENSMUST00000070577.5
1700030J22Rik
RIKEN cDNA 1700030J22 gene
chr12_+_111166536 0.953 ENSMUST00000060274.6
Traf3
TNF receptor-associated factor 3
chr11_+_117115133 0.930 ENSMUST00000021177.8
Sec14l1
SEC14-like 1 (S. cerevisiae)
chr8_-_54724474 0.930 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr17_+_68837062 0.929 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr9_-_49486209 0.927 ENSMUST00000055096.4
Ttc12
tetratricopeptide repeat domain 12
chr10_-_85916902 0.917 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr8_-_54724317 0.907 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr15_+_98708187 0.881 ENSMUST00000003444.4
Ccdc65
coiled-coil domain containing 65
chr9_-_22002599 0.879 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr5_+_130448801 0.878 ENSMUST00000111288.2
Caln1
calneuron 1
chr7_-_144939823 0.871 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr11_+_60353324 0.866 ENSMUST00000070805.6
ENSMUST00000094140.2
ENSMUST00000108723.2
ENSMUST00000108722.4
Lrrc48



leucine rich repeat containing 48



chr2_-_101628930 0.854 ENSMUST00000099682.2
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr2_+_125859134 0.845 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr11_-_30268169 0.844 ENSMUST00000006629.7
Sptbn1
spectrin beta, non-erythrocytic 1
chr8_-_45382198 0.833 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr2_+_21205719 0.830 ENSMUST00000054591.3
ENSMUST00000102952.1
ENSMUST00000138965.1
ENSMUST00000138914.1
ENSMUST00000102951.1
Thnsl1




threonine synthase-like 1 (bacterial)




chr1_-_160212864 0.825 ENSMUST00000014370.5
Cacybp
calcyclin binding protein
chr8_-_95142477 0.822 ENSMUST00000034240.7
ENSMUST00000169748.1
Kifc3

kinesin family member C3

chr2_-_152398046 0.821 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr8_+_123212857 0.809 ENSMUST00000060133.6
Spata33
spermatogenesis associated 33
chr2_-_35336969 0.807 ENSMUST00000028241.6
Stom
stomatin
chr5_-_117389029 0.788 ENSMUST00000111953.1
ENSMUST00000086461.6
Rfc5

replication factor C (activator 1) 5

chr7_+_46847128 0.785 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chrX_-_122397351 0.767 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr1_+_85928727 0.747 ENSMUST00000129392.1
4933407L21Rik
RIKEN cDNA 4933407L21 gene
chr1_-_87510306 0.738 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor
chr2_+_71389239 0.737 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr18_+_23803962 0.736 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr7_+_119896292 0.733 ENSMUST00000106517.1
Lyrm1
LYR motif containing 1
chr2_+_180589245 0.730 ENSMUST00000029087.3
Ogfr
opioid growth factor receptor
chr6_-_24515036 0.725 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr17_+_25471564 0.724 ENSMUST00000025002.1
Tekt4
tektin 4
chr2_-_134644019 0.724 ENSMUST00000110120.1
Tmx4
thioredoxin-related transmembrane protein 4
chr4_+_12906838 0.714 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr2_-_101628958 0.710 ENSMUST00000111231.3
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr9_+_59578192 0.703 ENSMUST00000118549.1
ENSMUST00000034840.3
Celf6

CUGBP, Elav-like family member 6

chr7_-_141214080 0.696 ENSMUST00000026573.5
ENSMUST00000170841.1
1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr15_-_85578070 0.689 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chr2_+_152669461 0.685 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
H13



histocompatibility 13



chr1_+_74332596 0.684 ENSMUST00000087225.5
Pnkd
paroxysmal nonkinesiogenic dyskinesia
chrX_-_163761323 0.657 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chrX_+_135885851 0.644 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
Bhlhb9


basic helix-loop-helix domain containing, class B9


chr14_+_57999305 0.639 ENSMUST00000180534.1
3110083C13Rik
RIKEN cDNA 3110083C13 gene
chr2_-_25224653 0.635 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr11_+_102881204 0.634 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr11_-_121388186 0.633 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr15_-_79834224 0.618 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
Cbx6

Npcd

chromobox 6

neuronal pentraxin chromo domain

chr1_-_72536930 0.616 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr14_+_63436394 0.605 ENSMUST00000121288.1
Fam167a
family with sequence similarity 167, member A
chr19_-_57197556 0.604 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr9_+_119937606 0.602 ENSMUST00000035100.5
Ttc21a
tetratricopeptide repeat domain 21A
chr3_+_146852359 0.598 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr9_-_21291124 0.590 ENSMUST00000086374.6
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr12_+_78861693 0.589 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr4_-_12087912 0.588 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr8_+_114439655 0.584 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
Wwox



WW domain-containing oxidoreductase



chr2_+_152962485 0.583 ENSMUST00000099197.2
ENSMUST00000103155.3
Ttll9

tubulin tyrosine ligase-like family, member 9

chr3_-_53863764 0.576 ENSMUST00000122330.1
ENSMUST00000146598.1
Ufm1

ubiquitin-fold modifier 1

chr4_+_6191093 0.568 ENSMUST00000029907.5
Ubxn2b
UBX domain protein 2B
chr2_-_152831112 0.567 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr8_-_105758570 0.562 ENSMUST00000155038.2
ENSMUST00000013294.9
Gfod2

glucose-fructose oxidoreductase domain containing 2

chr8_+_107150621 0.562 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr17_+_80290206 0.558 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr7_+_100495987 0.546 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr19_-_57197435 0.544 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr11_+_59948206 0.543 ENSMUST00000081980.6
Med9
mediator of RNA polymerase II transcription, subunit 9 homolog (yeast)
chr10_+_83722865 0.542 ENSMUST00000150459.1
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr11_-_106998483 0.542 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr8_+_111940697 0.541 ENSMUST00000034428.7
Gabarapl2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
chr11_+_108425192 0.540 ENSMUST00000150863.2
ENSMUST00000061287.5
ENSMUST00000149683.2
Cep112


centrosomal protein 112


chr19_-_57197377 0.523 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr10_-_128645965 0.521 ENSMUST00000133342.1
Ikzf4
IKAROS family zinc finger 4
chr19_-_57197496 0.518 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr11_-_78165521 0.516 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr9_+_22411515 0.513 ENSMUST00000058868.7
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr4_-_41569502 0.510 ENSMUST00000108049.2
ENSMUST00000108052.3
ENSMUST00000108050.1
Fam219a


family with sequence similarity 219, member A


chr2_+_112239468 0.498 ENSMUST00000028554.3
Lpcat4
lysophosphatidylcholine acyltransferase 4
chr7_-_105399991 0.498 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr7_-_4684963 0.497 ENSMUST00000079970.4
Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr9_+_110476985 0.496 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
Kif9



kinesin family member 9



chr2_+_32775769 0.481 ENSMUST00000066352.5
Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr3_-_82074639 0.480 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr5_+_29195983 0.474 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr15_-_33687840 0.471 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr9_+_63602650 0.469 ENSMUST00000041551.7
Aagab
alpha- and gamma-adaptin binding protein
chr8_+_123518835 0.446 ENSMUST00000093043.5
Gas8
growth arrest specific 8
chr4_+_41569775 0.445 ENSMUST00000102963.3
Dnaic1
dynein, axonemal, intermediate chain 1
chr4_+_109343029 0.445 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr17_+_71673255 0.445 ENSMUST00000097284.3
Fam179a
family with sequence similarity 179, member A
chr7_+_119895836 0.442 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr7_-_68749170 0.441 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr4_+_117252010 0.434 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr3_-_107931579 0.432 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
Gstm7



glutathione S-transferase, mu 7



chr11_-_102880981 0.427 ENSMUST00000107060.1
Eftud2
elongation factor Tu GTP binding domain containing 2
chr11_-_120991305 0.426 ENSMUST00000018274.3
Csnk1d
casein kinase 1, delta
chr2_+_174330006 0.422 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr7_-_44892358 0.412 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr10_-_93589621 0.411 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr4_+_126058557 0.410 ENSMUST00000035497.4
Oscp1
organic solute carrier partner 1
chr16_+_44394771 0.409 ENSMUST00000099742.2
Wdr52
WD repeat domain 52
chr19_+_6046576 0.408 ENSMUST00000138532.1
ENSMUST00000129081.1
ENSMUST00000156550.1
Syvn1


synovial apoptosis inhibitor 1, synoviolin


chr9_-_72985344 0.408 ENSMUST00000124565.2
Gm5918
predicted gene 5918
chr19_-_7206234 0.406 ENSMUST00000123594.1
ENSMUST00000025679.4
Otub1

OTU domain, ubiquitin aldehyde binding 1

chr11_+_120633719 0.403 ENSMUST00000181502.1
Gm17586
predicted gene, 17586
chr14_+_46760526 0.403 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr17_+_34644764 0.403 ENSMUST00000036720.8
Fkbpl
FK506 binding protein-like
chr4_+_118409331 0.401 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr11_-_102880925 0.398 ENSMUST00000021306.7
Eftud2
elongation factor Tu GTP binding domain containing 2
chr2_-_165034770 0.392 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr7_+_139214661 0.392 ENSMUST00000135509.1
Lrrc27
leucine rich repeat containing 27
chr10_+_69213084 0.392 ENSMUST00000163497.1
ENSMUST00000164212.1
ENSMUST00000067908.7
Rhobtb1


Rho-related BTB domain containing 1


chr4_-_44084167 0.390 ENSMUST00000030201.7
Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr10_-_128645784 0.389 ENSMUST00000065334.3
Ikzf4
IKAROS family zinc finger 4
chr3_-_116508035 0.389 ENSMUST00000153005.1
Rtca
RNA 3'-terminal phosphate cyclase
chr5_+_21645813 0.388 ENSMUST00000148873.1
ENSMUST00000072896.6
Armc10

armadillo repeat containing 10

chr12_+_76765527 0.387 ENSMUST00000137826.1
ENSMUST00000041262.7
ENSMUST00000126408.1
ENSMUST00000110399.2
Fntb
Churc1


farnesyltransferase, CAAX box, beta
churchill domain containing 1


chr2_+_136891501 0.386 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr13_-_108158584 0.382 ENSMUST00000163558.1
Ndufaf2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
chr7_-_44375006 0.377 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr8_-_64733534 0.374 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chrX_+_151198078 0.367 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
Wnk3


WNK lysine deficient protein kinase 3


chr14_+_57424054 0.364 ENSMUST00000122063.1
Ift88
intraflagellar transport 88
chr11_+_79660532 0.364 ENSMUST00000155381.1
Rab11fip4
RAB11 family interacting protein 4 (class II)
chr7_-_66689589 0.361 ENSMUST00000124899.1
Asb7
ankyrin repeat and SOCS box-containing 7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.8 1.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.8 2.3 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.4 4.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.4 2.1 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.4 1.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.4 1.6 GO:0046898 response to cycloheximide(GO:0046898)
0.4 2.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 6.6 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.6 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.3 2.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 1.0 GO:2000832 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.3 1.3 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 1.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.2 1.9 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.2 0.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 0.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 0.7 GO:0040010 positive regulation of growth rate(GO:0040010)
0.2 0.5 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.8 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 1.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 1.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.4 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 4.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 1.4 GO:0051451 myoblast migration(GO:0051451)
0.1 0.2 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.4 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 5.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.1 3.3 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 0.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 2.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 1.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.1 3.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:1903564 protein localization to ciliary membrane(GO:1903441) regulation of protein localization to cilium(GO:1903564)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 2.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.8 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 1.1 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.9 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.6 GO:0007099 centriole replication(GO:0007099)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.9 GO:0061371 determination of heart left/right asymmetry(GO:0061371)
0.0 1.6 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 0.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.5 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.0 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.0 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.3 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.0 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.0 GO:0034310 primary alcohol catabolic process(GO:0034310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.3 4.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 1.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 2.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.2 GO:0000235 astral microtubule(GO:0000235)
0.2 0.4 GO:0033503 HULC complex(GO:0033503)
0.2 0.8 GO:0032437 cuticular plate(GO:0032437)
0.2 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 1.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 3.3 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.6 GO:0045298 tubulin complex(GO:0045298)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.9 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.0 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.8 GO:0030017 sarcomere(GO:0030017)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.1 GO:0045202 synapse(GO:0045202)
0.0 0.2 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.5 1.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 1.7 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 4.9 GO:0031996 thioesterase binding(GO:0031996)
0.4 1.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 1.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 0.8 GO:0004335 galactokinase activity(GO:0004335)
0.2 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.6 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.5 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.5 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.6 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.5 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 2.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 4.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0030172 troponin C binding(GO:0030172)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 3.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 1.0 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 5.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.5 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 4.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.6 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.8 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.1 1.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 5.1 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.7 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.5 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 2.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.5 REACTOME_LIPOPROTEIN_METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.8 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA