Motif ID: Rhox11

Z-value: 0.356


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_126556935 1.598 ENSMUST00000048391.8
 Clspn
claspin
chr5_+_21186267 1.256 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr4_+_126556994 1.246 ENSMUST00000147675.1
 Clspn
claspin
chr15_+_25742314 1.153 ENSMUST00000135981.1
 Myo10
myosin X
chr11_-_100355383 1.051 ENSMUST00000146878.2
 Hap1
huntingtin-associated protein 1
chr3_-_121171678 0.955 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
 Rwdd3




RWD domain containing 3




chr5_+_111733924 0.906 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr17_-_47016956 0.893 ENSMUST00000165525.1
 Gm16494
predicted gene 16494
chr10_+_58394381 0.881 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr14_-_20496780 0.814 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr10_+_58394361 0.788 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chrX_-_102157065 0.700 ENSMUST00000056904.2
 Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr5_+_17574268 0.629 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_127791374 0.627 ENSMUST00000171621.1
 Tifa
TRAF-interacting protein with forkhead-associated domain
chr5_+_17574726 0.613 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_+_104831572 0.593 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr3_+_156561792 0.570 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr12_-_99883429 0.562 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr15_+_36179299 0.488 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr5_+_93093428 0.476 ENSMUST00000074733.7
 Sept11
septin 11
chr13_+_95325195 0.474 ENSMUST00000045909.7
 Zbed3
zinc finger, BED domain containing 3
chr15_+_8169067 0.451 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr2_-_5862923 0.450 ENSMUST00000071016.2
 Gm13199
predicted gene 13199
chr9_-_60838200 0.449 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr5_+_138187485 0.399 ENSMUST00000110934.2
 Cnpy4
canopy 4 homolog (zebrafish)
chr11_+_29373618 0.382 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr13_-_23562369 0.375 ENSMUST00000105107.1
 Hist1h3e
histone cluster 1, H3e
chr1_-_175688353 0.360 ENSMUST00000104984.1
 Chml
choroideremia-like
chr7_-_46795881 0.327 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr15_+_41789495 0.327 ENSMUST00000090095.5
ENSMUST00000022918.7
 Oxr1

oxidation resistance 1

chr7_-_46795661 0.318 ENSMUST00000123725.1
 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr6_-_34977999 0.282 ENSMUST00000044387.7
 2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr11_-_102082464 0.282 ENSMUST00000100398.4
 Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_-_105827190 0.279 ENSMUST00000041400.5
 Ranbp10
RAN binding protein 10
chr19_-_60581013 0.270 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
 Cacul1


CDK2 associated, cullin domain 1


chr5_+_121220191 0.268 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chr2_-_150362708 0.261 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr7_-_28008416 0.258 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chrX_-_111536325 0.251 ENSMUST00000156639.1
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr7_-_30664986 0.227 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr8_+_3353415 0.217 ENSMUST00000098966.3
 A430078G23Rik
RIKEN cDNA A430078G23 gene
chrX_+_105079761 0.208 ENSMUST00000119477.1
 Pbdc1
polysaccharide biosynthesis domain containing 1
chr4_-_137048695 0.206 ENSMUST00000049583.7
 Zbtb40
zinc finger and BTB domain containing 40
chr13_-_3611064 0.196 ENSMUST00000096069.3
 BC016423
cDNA sequence BC016423
chr6_+_128662379 0.192 ENSMUST00000032518.4
 Clec2h
C-type lectin domain family 2, member h
chrX_+_105079735 0.189 ENSMUST00000033577.4
 Pbdc1
polysaccharide biosynthesis domain containing 1
chr18_-_56572888 0.176 ENSMUST00000174518.1
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_+_98329298 0.173 ENSMUST00000080333.3
 1700007G11Rik
RIKEN cDNA 1700007G11 gene
chr9_+_50768228 0.154 ENSMUST00000042391.6
 Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr8_-_81014866 0.152 ENSMUST00000042724.6
 Usp38
ubiquitin specific peptidase 38
chr17_+_79614900 0.151 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr1_+_169969409 0.150 ENSMUST00000180638.1
 3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr5_+_110135823 0.149 ENSMUST00000112519.2
ENSMUST00000014812.8
 Chfr

checkpoint with forkhead and ring finger domains

chr9_-_8134294 0.148 ENSMUST00000037397.6
 AK129341
cDNA sequence AK129341
chr9_-_20521375 0.137 ENSMUST00000068296.7
ENSMUST00000174462.1
 Zfp266

zinc finger protein 266

chr15_+_7129557 0.125 ENSMUST00000067190.5
ENSMUST00000164529.1
 Lifr

leukemia inhibitory factor receptor

chr13_-_71963713 0.124 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr8_+_94386438 0.121 ENSMUST00000161576.1
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr13_+_49653297 0.118 ENSMUST00000021824.7
 Nol8
nucleolar protein 8
chr9_-_107289847 0.095 ENSMUST00000035194.2
 Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr8_+_94386486 0.089 ENSMUST00000034220.7
 Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr2_-_131352857 0.085 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr2_-_6935081 0.079 ENSMUST00000100426.2
 Gm10855
predicted gene 10855
chr3_+_90603767 0.076 ENSMUST00000001046.5
ENSMUST00000107330.1
 S100a4

S100 calcium binding protein A4

chr9_-_67043709 0.072 ENSMUST00000113689.1
ENSMUST00000113684.1
 Tpm1

tropomyosin 1, alpha

chr1_+_24177610 0.063 ENSMUST00000054588.8
 Col9a1
collagen, type IX, alpha 1
chr10_+_21295979 0.060 ENSMUST00000020153.8
ENSMUST00000092674.6
 Hbs1l

Hbs1-like (S. cerevisiae)

chr11_-_5381734 0.056 ENSMUST00000172492.1
 Znrf3
zinc and ring finger 3
chr9_-_16378231 0.054 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr11_-_102880981 0.046 ENSMUST00000107060.1
 Eftud2
elongation factor Tu GTP binding domain containing 2
chr14_-_46822232 0.045 ENSMUST00000111817.1
ENSMUST00000079314.5
 Gmfb

glia maturation factor, beta

chr9_-_44713196 0.040 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr9_-_50768109 0.036 ENSMUST00000177546.1
ENSMUST00000176238.1
 1110032A03Rik

RIKEN cDNA 1110032A03 gene

chr11_-_97700327 0.027 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr1_+_99772765 0.024 ENSMUST00000086738.3
 Cntnap5b
contactin associated protein-like 5B
chr9_-_110654161 0.022 ENSMUST00000133191.1
ENSMUST00000167320.1
 Nbeal2

neurobeachin-like 2

chr11_-_102880925 0.015 ENSMUST00000021306.7
 Eftud2
elongation factor Tu GTP binding domain containing 2
chr13_+_47043499 0.002 ENSMUST00000037025.8
ENSMUST00000143868.1
 Kdm1b

lysine (K)-specific demethylase 1B

chr1_-_169969143 0.001 ENSMUST00000027989.6
ENSMUST00000111353.3
 Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

chr11_+_70639118 0.001 ENSMUST00000055184.6
ENSMUST00000108551.2
 Gp1ba

glycoprotein 1b, alpha polypeptide


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.0 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.3 2.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 1.1 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 1.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 1.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling