Motif ID: Rora

Z-value: 0.395


Transcription factors associated with Rora:

Gene SymbolEntrez IDGene Name
Rora ENSMUSG00000032238.11 Rora

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Roramm10_v2_chr9_+_68653761_68653786-0.163.3e-01Click!


Activity profile for motif Rora.

activity profile for motif Rora


Sorted Z-values histogram for motif Rora

Sorted Z-values for motif Rora



Network of associatons between targets according to the STRING database.



First level regulatory network of Rora

PNG image of the network

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Top targets:


Showing 1 to 20 of 185 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66801577 2.578 ENSMUST00000168589.1
 Sla
src-like adaptor
chr1_+_159737510 1.416 ENSMUST00000111669.3
 Tnr
tenascin R
chr2_-_5676046 1.394 ENSMUST00000114987.3
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr9_-_75597643 1.366 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr19_-_57314896 1.341 ENSMUST00000111524.1
 Ablim1
actin-binding LIM protein 1
chr2_+_170731807 1.093 ENSMUST00000029075.4
 Dok5
docking protein 5
chr11_+_42419729 1.056 ENSMUST00000007797.4
 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr1_+_32172711 0.898 ENSMUST00000027226.5
 Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr3_-_107517321 0.890 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr7_-_12422751 0.809 ENSMUST00000080348.5
 Zfp551
zinc fingr protein 551
chr5_+_37028329 0.782 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr11_+_97450136 0.761 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr2_+_4300462 0.740 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr15_-_72546279 0.717 ENSMUST00000044624.6
 Kcnk9
potassium channel, subfamily K, member 9
chr19_-_37207293 0.704 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
 Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr3_-_158562199 0.688 ENSMUST00000106044.1
 Lrrc7
leucine rich repeat containing 7
chr15_+_99224976 0.679 ENSMUST00000041415.3
 Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr12_+_33314277 0.674 ENSMUST00000133549.1
 Atxn7l1
ataxin 7-like 1
chr1_+_127204986 0.652 ENSMUST00000038361.4
 Mgat5
mannoside acetylglucosaminyltransferase 5
chr16_+_11406618 0.640 ENSMUST00000122168.1
 Snx29
sorting nexin 29

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.5 1.5 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.4 1.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.7 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.2 0.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.5 GO:0035902 response to immobilization stress(GO:0035902)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 1.4 GO:0072534 perineuronal net(GO:0072534)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.1 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 0.5 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters