Motif ID: Runx2_Bcl11a

Z-value: 1.317

Transcription factors associated with Runx2_Bcl11a:

Gene SymbolEntrez IDGene Name
Bcl11a ENSMUSG00000000861.9 Bcl11a
Runx2 ENSMUSG00000039153.10 Runx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl11amm10_v2_chr11_+_24078111_240781340.231.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103827922 13.818 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr15_-_66801577 10.084 ENSMUST00000168589.1
Sla
src-like adaptor
chr11_-_83649349 7.853 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr4_-_136892867 7.224 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr8_-_11008458 6.795 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr19_+_3935186 6.648 ENSMUST00000162708.1
ENSMUST00000165711.1
Unc93b1

unc-93 homolog B1 (C. elegans)

chr3_-_87263518 6.402 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr1_-_172297989 6.040 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr1_+_58210397 6.006 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr4_+_144892813 5.670 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_-_77408034 5.506 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chr1_-_140183404 5.498 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr5_+_90772435 5.262 ENSMUST00000031320.6
Pf4
platelet factor 4
chr11_+_101246960 5.192 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr15_+_3270767 5.054 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr15_-_37459327 4.634 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr13_-_37050237 4.561 ENSMUST00000164727.1
F13a1
coagulation factor XIII, A1 subunit
chr5_+_37047464 4.474 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chrX_+_159697308 4.447 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr11_-_106388066 4.422 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr4_+_48049080 4.323 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr1_+_169655493 4.262 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr3_-_87263703 4.147 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr13_+_76579670 4.105 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr19_+_47854970 3.885 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr2_-_25470031 3.776 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr11_+_78322965 3.765 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr8_+_104170513 3.737 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr18_+_32938955 3.569 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr5_+_37050854 3.506 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_75567176 3.334 ENSMUST00000156032.1
ENSMUST00000127095.1
Ly6h

lymphocyte antigen 6 complex, locus H

chr11_+_3330781 3.315 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr7_-_142661858 3.217 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr10_-_62379852 3.206 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr4_+_144893127 3.142 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr18_+_37496997 3.113 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr11_-_98329641 3.088 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr11_+_105975204 3.067 ENSMUST00000001964.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr5_-_124187150 3.065 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr15_-_76660108 3.040 ENSMUST00000066677.8
ENSMUST00000177359.1
Cyhr1

cysteine and histidine rich 1

chr19_-_20390944 3.015 ENSMUST00000025561.7
Anxa1
annexin A1
chr4_-_14621805 2.961 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr4_+_128058962 2.868 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr5_-_44799643 2.852 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr11_-_76577701 2.820 ENSMUST00000176179.1
Abr
active BCR-related gene
chr7_-_142666816 2.818 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr3_-_142169311 2.817 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr7_-_126676357 2.785 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr9_-_103219823 2.769 ENSMUST00000168142.1
Trf
transferrin
chr1_+_45311538 2.755 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr1_-_140183283 2.755 ENSMUST00000111977.1
Cfh
complement component factor h
chr9_+_121642716 2.730 ENSMUST00000035115.4
Vipr1
vasoactive intestinal peptide receptor 1
chr7_+_49246812 2.719 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr6_+_17491216 2.663 ENSMUST00000080469.5
Met
met proto-oncogene
chrX_+_151344171 2.653 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr5_-_146585239 2.637 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr6_-_126645784 2.621 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr1_-_169747634 2.601 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr5_+_24364804 2.566 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr4_-_46991842 2.549 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_-_90129339 2.501 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr6_+_17749170 2.483 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr11_-_101785252 2.475 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr15_-_37458523 2.427 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr4_-_138396438 2.388 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr3_+_90514435 2.338 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr12_+_36314160 2.303 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr11_+_82045705 2.271 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr16_+_91391721 2.266 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr18_+_37355271 2.247 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr3_-_90514250 2.228 ENSMUST00000107340.1
ENSMUST00000060738.8
S100a1

S100 calcium binding protein A1

chr9_-_77251829 2.162 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chrX_-_48034842 2.159 ENSMUST00000039026.7
Apln
apelin
chr5_+_104435112 2.157 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
Spp1





secreted phosphoprotein 1





chr19_-_57118897 2.149 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr2_-_168741752 2.140 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chr16_+_42907563 2.133 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr3_-_88000350 2.125 ENSMUST00000090971.5
Bcan
brevican
chr19_-_5273080 2.114 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr13_+_49608030 2.109 ENSMUST00000021822.5
Ogn
osteoglycin
chr13_-_84064772 2.090 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr7_-_126676428 2.089 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr11_-_110168073 2.087 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_+_144893077 2.061 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr10_+_61171954 2.060 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr19_-_57197377 1.957 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr11_+_3330401 1.951 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr19_-_57197496 1.950 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197435 1.944 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr7_-_78577771 1.934 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr11_-_100414829 1.895 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chr10_-_62507737 1.861 ENSMUST00000020271.6
Srgn
serglycin
chr13_+_16014457 1.853 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr11_-_116654245 1.837 ENSMUST00000021166.5
Cygb
cytoglobin
chr7_+_19176416 1.836 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr16_-_3907651 1.811 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr10_-_81291227 1.785 ENSMUST00000045744.6
Tjp3
tight junction protein 3
chr9_+_90054529 1.767 ENSMUST00000143172.1
Ctsh
cathepsin H
chr17_-_35175995 1.758 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr14_+_80000292 1.757 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr13_+_63014934 1.738 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr1_-_72874877 1.732 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr19_-_4125837 1.729 ENSMUST00000121402.1
ENSMUST00000117831.1
Aip

aryl-hydrocarbon receptor-interacting protein

chr19_+_6400523 1.712 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr4_+_102254739 1.705 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr17_-_45592569 1.694 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr1_-_168431695 1.689 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr2_-_156992021 1.684 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3


N-myc downstream regulated gene 3


chr2_-_132111440 1.679 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr2_+_4300462 1.662 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr2_+_121357714 1.649 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr18_+_37518341 1.638 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr4_+_108719649 1.634 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr17_+_3532554 1.604 ENSMUST00000168560.1
Cldn20
claudin 20
chr1_-_168432270 1.582 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr5_+_89027959 1.559 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr5_+_66968961 1.543 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr17_+_8849974 1.542 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr17_+_35236556 1.539 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr9_+_49518336 1.538 ENSMUST00000068730.3
Gm11149
predicted gene 11149
chr11_-_54860564 1.533 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr8_+_25518783 1.525 ENSMUST00000084027.5
ENSMUST00000117179.2
Fgfr1

fibroblast growth factor receptor 1

chr9_-_77251871 1.521 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr4_+_152199805 1.515 ENSMUST00000105652.2
Acot7
acyl-CoA thioesterase 7
chr15_-_71727815 1.510 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr18_+_36939178 1.508 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr10_+_80356459 1.504 ENSMUST00000039836.8
ENSMUST00000105351.1
Plk5

polo-like kinase 5

chr11_+_120721452 1.500 ENSMUST00000018156.5
Rac3
RAS-related C3 botulinum substrate 3
chr1_-_136260873 1.495 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr15_-_79834323 1.481 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chrX_-_57338598 1.467 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr5_-_122002340 1.467 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr7_-_141010759 1.462 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr6_+_51432663 1.459 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr1_+_75549581 1.452 ENSMUST00000154101.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr1_-_195131536 1.438 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr11_-_52282564 1.432 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr10_+_43579161 1.412 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr4_-_14621669 1.408 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_-_127970951 1.401 ENSMUST00000030614.2
CK137956
cDNA sequence CK137956
chr11_-_109472611 1.399 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_+_127172866 1.394 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr12_-_4592927 1.391 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr10_-_81025521 1.382 ENSMUST00000144640.1
Diras1
DIRAS family, GTP-binding RAS-like 1
chr14_-_66280949 1.374 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr14_-_51913393 1.366 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr7_+_45575100 1.350 ENSMUST00000140077.1
Bcat2
branched chain aminotransferase 2, mitochondrial
chr3_-_54915867 1.348 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr15_+_92597104 1.346 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr19_-_4305955 1.342 ENSMUST00000025791.5
Adrbk1
adrenergic receptor kinase, beta 1
chr8_+_25518757 1.342 ENSMUST00000178276.1
ENSMUST00000179592.1
Fgfr1

fibroblast growth factor receptor 1

chr3_+_86070915 1.339 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr4_+_123183456 1.327 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr3_-_108017877 1.314 ENSMUST00000004140.4
Gstm1
glutathione S-transferase, mu 1
chr10_+_42502030 1.306 ENSMUST00000105500.1
ENSMUST00000019939.5
Snx3

sorting nexin 3

chr11_+_98348404 1.297 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr5_-_125294107 1.295 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr3_-_107760221 1.294 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr7_+_49974864 1.275 ENSMUST00000081872.5
ENSMUST00000151721.1
Nell1

NEL-like 1

chr4_+_102589687 1.271 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr15_-_100584075 1.264 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr6_+_55836878 1.262 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr2_+_70562007 1.248 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr4_+_126148457 1.245 ENSMUST00000106150.2
Eva1b
eva-1 homolog B (C. elegans)
chr5_+_34549595 1.241 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr11_+_69326252 1.241 ENSMUST00000018614.2
Kcnab3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr4_-_14621494 1.229 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr15_-_79285502 1.218 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr13_-_51734695 1.214 ENSMUST00000110039.1
Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr6_+_94500313 1.212 ENSMUST00000061118.8
Slc25a26
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr3_+_96181151 1.203 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr19_+_55253369 1.200 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chrX_-_162643629 1.198 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr17_-_45592485 1.196 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_98753512 1.193 ENSMUST00000124072.1
Thra
thyroid hormone receptor alpha
chr17_-_45592262 1.191 ENSMUST00000164769.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_127824469 1.188 ENSMUST00000106267.3
Stx1b
syntaxin 1B
chr2_+_140395309 1.187 ENSMUST00000110067.1
ENSMUST00000110064.1
ENSMUST00000110063.1
ENSMUST00000110062.1
ENSMUST00000078027.5
ENSMUST00000043836.7
Macrod2





MACRO domain containing 2





chr15_-_53902472 1.179 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr13_-_97198351 1.179 ENSMUST00000022169.7
Hexb
hexosaminidase B
chr16_-_97922582 1.173 ENSMUST00000170757.1
C2cd2
C2 calcium-dependent domain containing 2
chr8_-_70212251 1.170 ENSMUST00000063788.7
Slc25a42
solute carrier family 25, member 42
chr13_+_54949388 1.165 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr10_+_75316943 1.161 ENSMUST00000105420.1
Adora2a
adenosine A2a receptor
chr9_+_98296556 1.153 ENSMUST00000035031.6
ENSMUST00000112935.1
Nmnat3

nicotinamide nucleotide adenylyltransferase 3

chr8_+_27260327 1.148 ENSMUST00000033880.5
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr1_-_120074023 1.142 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr1_+_172499948 1.140 ENSMUST00000111230.1
Tagln2
transgelin 2
chr4_+_136284658 1.136 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr19_+_26750939 1.132 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_29528382 1.098 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr5_+_89028035 1.097 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr10_-_81025406 1.093 ENSMUST00000055125.4
Diras1
DIRAS family, GTP-binding RAS-like 1
chr11_-_110095937 1.091 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr4_-_134254076 1.083 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr2_-_26021532 1.081 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr11_-_109473220 1.073 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr12_-_72070991 1.070 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr15_+_81987835 1.062 ENSMUST00000165777.1
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr11_-_106579111 1.051 ENSMUST00000103070.2
Tex2
testis expressed gene 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
2.0 6.0 GO:0046110 xanthine metabolic process(GO:0046110)
1.6 4.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.5 4.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.4 4.3 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.4 8.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.3 6.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
1.3 3.9 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.1 3.4 GO:0050975 sensory perception of touch(GO:0050975)
1.1 5.6 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
1.1 5.3 GO:0045347 regulation of cytolysis(GO:0042268) negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
1.0 7.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
1.0 3.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.0 3.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.0 3.0 GO:0036292 positive regulation of prostaglandin biosynthetic process(GO:0031394) DNA rewinding(GO:0036292) neutrophil clearance(GO:0097350) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.0 9.0 GO:0043615 astrocyte cell migration(GO:0043615)
1.0 11.0 GO:0042572 retinol metabolic process(GO:0042572)
1.0 7.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.0 2.9 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.9 5.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.8 5.6 GO:0019532 oxalate transport(GO:0019532)
0.8 2.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.8 3.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.7 5.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.7 2.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.7 2.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.7 2.7 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.7 2.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.7 6.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.6 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.6 1.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.6 1.9 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.6 1.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.6 1.8 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.6 4.1 GO:0015862 uridine transport(GO:0015862)
0.6 1.7 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.6 2.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.6 2.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.2 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.5 2.4 GO:0051182 coenzyme transport(GO:0051182)
0.5 1.4 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5 3.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 3.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 1.4 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.5 1.4 GO:0006550 isoleucine catabolic process(GO:0006550)
0.4 4.9 GO:0051923 sulfation(GO:0051923)
0.4 1.8 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.4 2.5 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.4 3.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.4 1.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 1.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4 1.9 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 1.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.4 1.8 GO:0015671 oxygen transport(GO:0015671)
0.4 1.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.3 2.8 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 0.7 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.3 4.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 1.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.3 1.2 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.3 1.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 1.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 2.7 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.3 1.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.3 1.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 0.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 3.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 2.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.4 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.2 0.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 1.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 0.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.4 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 0.8 GO:0060431 primary lung bud formation(GO:0060431)
0.2 2.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 0.6 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.2 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 1.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 1.0 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 0.4 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 1.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.3 GO:0055064 carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064)
0.2 1.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 0.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2 1.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.9 GO:0048245 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683)
0.2 1.5 GO:0002347 response to tumor cell(GO:0002347)
0.2 1.5 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.2 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 4.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 0.8 GO:0001705 ectoderm formation(GO:0001705)
0.2 0.8 GO:0043312 neutrophil degranulation(GO:0043312)
0.2 1.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 0.6 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.9 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 9.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 1.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 6.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.9 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.9 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 3.0 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.9 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.7 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 6.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 1.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.6 GO:0007031 peroxisome organization(GO:0007031)
0.1 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 4.9 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.3 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.3 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 1.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.4 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.4 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.6 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 0.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 2.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.7 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.2 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.2 GO:0015744 succinate transport(GO:0015744)
0.0 7.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.7 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 2.5 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.0 1.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.5 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 2.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.2 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 1.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.7 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 1.5 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.0 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0046654 purine nucleobase biosynthetic process(GO:0009113) tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0021612 facial nerve structural organization(GO:0021612)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0051096 maintenance of DNA repeat elements(GO:0043570) regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 1.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:0015844 monoamine transport(GO:0015844)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:0036371 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.0 1.3 GO:0051607 defense response to virus(GO:0051607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.0 5.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.9 6.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.9 8.7 GO:0032009 early phagosome(GO:0032009)
0.7 2.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 3.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.6 1.9 GO:0043512 inhibin A complex(GO:0043512)
0.6 4.9 GO:0042629 mast cell granule(GO:0042629)
0.5 4.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 5.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.4 1.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.3 2.8 GO:0097433 dense body(GO:0097433)
0.3 1.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 0.9 GO:0044299 C-fiber(GO:0044299)
0.3 1.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 2.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 20.3 GO:0072562 blood microparticle(GO:0072562)
0.2 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 2.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0045098 type III intermediate filament(GO:0045098)
0.2 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 4.5 GO:0005604 basement membrane(GO:0005604)
0.2 1.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.7 GO:0071439 clathrin complex(GO:0071439)
0.2 2.6 GO:0097228 sperm principal piece(GO:0097228)
0.2 2.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.2 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0014802 terminal cisterna(GO:0014802)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 1.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:0042581 specific granule(GO:0042581)
0.1 0.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 3.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.3 GO:0031430 M band(GO:0031430)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 7.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.9 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.6 GO:0034709 methylosome(GO:0034709)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 3.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 10.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.3 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 9.7 GO:0045177 apical part of cell(GO:0045177)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.3 GO:0043204 perikaryon(GO:0043204)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.7 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:1990462 omegasome(GO:1990462)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 3.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.6 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 11.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
2.1 8.3 GO:0001851 complement component C3b binding(GO:0001851)
1.8 5.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.6 4.9 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.6 10.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.5 6.0 GO:0030151 molybdenum ion binding(GO:0030151)
1.2 3.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.1 4.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.1 5.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.0 5.2 GO:0097643 amylin receptor activity(GO:0097643)
0.9 3.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.9 2.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.8 3.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.8 3.1 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.8 3.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.8 3.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.7 0.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 2.7 GO:0004111 creatine kinase activity(GO:0004111)
0.7 2.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.7 2.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.7 6.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.6 1.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 2.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.6 1.7 GO:0036004 GAF domain binding(GO:0036004)
0.6 1.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.6 3.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 2.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 5.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.5 8.4 GO:0050811 GABA receptor binding(GO:0050811)
0.4 1.8 GO:0030984 kininogen binding(GO:0030984)
0.4 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.3 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 6.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.4 1.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 2.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 2.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 2.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.4 3.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 1.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 8.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.4 2.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 2.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 1.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 2.3 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.0 GO:0071723 lipopeptide binding(GO:0071723)
0.3 2.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 2.9 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.3 6.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 3.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 1.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 1.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 7.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 5.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.9 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 1.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 4.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 2.2 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 7.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 9.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 2.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 6.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.2 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.2 1.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.2 2.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 2.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 1.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.7 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 1.1 GO:0050897 cobalt ion binding(GO:0050897)
0.2 2.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0016151 nickel cation binding(GO:0016151)
0.1 1.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0070404 NADH binding(GO:0070404)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.3 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.1 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 0.3 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 3.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.1 7.1 GO:0008083 growth factor activity(GO:0008083)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) oligopeptide transmembrane transporter activity(GO:0035673) sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.5 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0030172 troponin C binding(GO:0030172)
0.1 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.3 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 3.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0071949 FAD binding(GO:0071949)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 2.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0019903 protein phosphatase binding(GO:0019903)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.1 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 0.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 6.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 5.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 31.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.7 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 5.5 PID_FGF_PATHWAY FGF signaling pathway
0.1 6.9 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 4.8 PID_SHP2_PATHWAY SHP2 signaling
0.1 1.8 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 2.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.2 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.5 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 5.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 3.3 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 1.0 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 10.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.0 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.9 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 2.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 1.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 0.8 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 4.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.2 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 2.8 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 2.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 2.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID_MYC_PATHWAY C-MYC pathway
0.0 1.0 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.9 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 2.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 5.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.0 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 1.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
1.7 8.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
1.3 7.9 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.7 6.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.7 4.9 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 8.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 1.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.5 11.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 3.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.3 6.9 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.3 3.9 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 8.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 2.9 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 4.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 1.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 5.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 4.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 2.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.2 2.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 4.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 6.2 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 5.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.2 1.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 4.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.7 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 5.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.8 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 2.1 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.7 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 1.2 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.0 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.7 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 0.2 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 3.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.2 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 1.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.1 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 5.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 0.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 2.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.6 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.5 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME_TOLL_RECEPTOR_CASCADES Genes involved in Toll Receptor Cascades
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis