Motif ID: Rxra

Z-value: 0.398


Transcription factors associated with Rxra:

Gene SymbolEntrez IDGene Name
Rxra ENSMUSG00000015846.8 Rxra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxramm10_v2_chr2_+_27677201_27677229-0.454.9e-03Click!


Activity profile for motif Rxra.

activity profile for motif Rxra


Sorted Z-values histogram for motif Rxra

Sorted Z-values for motif Rxra



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxra

PNG image of the network

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Top targets:


Showing 1 to 20 of 156 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_85205120 1.507 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr4_+_85205417 1.146 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
 Sh3gl2


SH3-domain GRB2-like 2


chr15_-_95528702 0.948 ENSMUST00000166170.1
 Nell2
NEL-like 2
chrX_+_6415736 0.870 ENSMUST00000143641.3
 Shroom4
shroom family member 4
chr2_+_59160838 0.787 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
 Pkp4


plakophilin 4


chr6_+_8259327 0.784 ENSMUST00000159378.1
 Gm16039
predicted gene 16039
chr6_+_71707561 0.768 ENSMUST00000121469.1
 Reep1
receptor accessory protein 1
chr2_+_121357714 0.751 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
 Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr12_-_74316394 0.751 ENSMUST00000110441.1
 Gm11042
predicted gene 11042
chr10_-_82623190 0.681 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
 1190007I07Rik


RIKEN cDNA 1190007I07 gene


chr7_-_14562171 0.630 ENSMUST00000181796.1
 Vmn1r90
vomeronasal 1 receptor 90
chr7_+_19212521 0.575 ENSMUST00000060225.4
 Gpr4
G protein-coupled receptor 4
chr9_+_110344185 0.550 ENSMUST00000142100.1
 Scap
SREBF chaperone
chr10_-_35711891 0.545 ENSMUST00000080898.2
 Amd2
S-adenosylmethionine decarboxylase 2
chr13_+_13590402 0.533 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr2_-_59160644 0.529 ENSMUST00000077687.5
 Ccdc148
coiled-coil domain containing 148
chr7_-_90129339 0.505 ENSMUST00000181189.1
 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr7_+_30169861 0.504 ENSMUST00000085668.4
 Gm5113
predicted gene 5113
chr13_+_18948344 0.499 ENSMUST00000003345.7
 Amph
amphiphysin
chr4_+_21879662 0.486 ENSMUST00000029909.2
 Coq3
coenzyme Q3 homolog, methyltransferase (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.9 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.9 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.8 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 0.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.6 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.4 GO:0007507 heart development(GO:0007507)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0016460 myosin II complex(GO:0016460)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.2 0.8 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0019808 polyamine binding(GO:0019808)
0.1 0.5 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins