Motif ID: Rxrb

Z-value: 0.557


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032071_34032196-0.076.9e-01Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_6487231 3.986 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr6_-_23248264 3.289 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_-_117178726 3.172 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr10_+_93641041 3.110 ENSMUST00000020204.4
Ntn4
netrin 4
chr1_+_74791516 2.471 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr4_+_44300876 2.122 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr10_-_88146867 1.988 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr14_+_54476100 1.901 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr11_-_40733373 1.898 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr14_-_118052235 1.770 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr6_+_113531675 1.660 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr5_+_110839973 1.564 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chrX_-_23365044 1.549 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr12_-_98737405 1.494 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_170306332 1.469 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr17_-_35704000 1.415 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr5_+_137630116 1.355 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_+_47984571 1.325 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr13_+_44729794 1.167 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr6_+_29396576 1.158 ENSMUST00000115275.1
Ccdc136
coiled-coil domain containing 136
chr6_+_29396665 1.086 ENSMUST00000096084.5
Ccdc136
coiled-coil domain containing 136
chr2_+_102706356 1.002 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr8_+_72135247 0.990 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr8_-_67910911 0.926 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_154548888 0.855 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr14_+_21500879 0.817 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr5_+_3803160 0.785 ENSMUST00000171023.1
ENSMUST00000080085.4
Krit1

KRIT1, ankyrin repeat containing

chr11_+_40733936 0.780 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr1_+_146420434 0.773 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr3_+_122729158 0.721 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr10_+_127195240 0.716 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr18_+_57142782 0.711 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr11_+_40733639 0.701 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr1_+_84839833 0.696 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr12_+_119945957 0.691 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr14_+_20929416 0.677 ENSMUST00000022369.7
Vcl
vinculin
chr5_+_108065742 0.654 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
Mtf2


metal response element binding transcription factor 2


chr4_-_45532470 0.585 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr14_-_118706180 0.570 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr17_+_17831004 0.546 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chrX_+_73716577 0.528 ENSMUST00000002084.7
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr5_+_119834663 0.525 ENSMUST00000018407.6
Tbx5
T-box 5
chr4_+_130047840 0.523 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr2_-_119477613 0.521 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr10_+_80148263 0.509 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr3_-_96172384 0.488 ENSMUST00000180958.1
Gm17690
predicted gene, 17690
chr7_+_35802593 0.476 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr6_+_120836201 0.455 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr5_+_108065696 0.445 ENSMUST00000172045.1
Mtf2
metal response element binding transcription factor 2
chr5_-_74702891 0.432 ENSMUST00000117388.1
Lnx1
ligand of numb-protein X 1
chr7_-_4778141 0.428 ENSMUST00000094892.5
Il11
interleukin 11
chr10_+_81136223 0.423 ENSMUST00000048128.8
Zbtb7a
zinc finger and BTB domain containing 7a
chr1_-_52499980 0.403 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr4_-_20778852 0.402 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr4_-_20778527 0.400 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr19_-_4615453 0.396 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr16_+_31663841 0.395 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr5_-_116422858 0.392 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr4_+_130047914 0.392 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr3_+_90062781 0.372 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chrX_+_73716712 0.357 ENSMUST00000114461.2
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr5_+_121795034 0.350 ENSMUST00000162327.1
Atxn2
ataxin 2
chr9_-_50659780 0.343 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr16_+_31663935 0.328 ENSMUST00000100001.3
ENSMUST00000064477.7
Dlg1

discs, large homolog 1 (Drosophila)

chr7_+_3290553 0.309 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr4_+_43632185 0.302 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr7_-_35802968 0.275 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr10_+_88147061 0.274 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr4_-_41048124 0.257 ENSMUST00000030136.6
Aqp7
aquaporin 7
chr13_+_55209776 0.254 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr10_+_127290774 0.250 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr4_+_57845240 0.243 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr10_+_88146992 0.231 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr2_+_173659834 0.210 ENSMUST00000109110.3
Rab22a
RAB22A, member RAS oncogene family
chr2_+_158794807 0.209 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr4_-_58912678 0.192 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr15_+_76797628 0.189 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr5_+_72914264 0.184 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr2_+_173659760 0.180 ENSMUST00000029024.3
Rab22a
RAB22A, member RAS oncogene family
chr12_-_113260217 0.178 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr5_-_134946917 0.175 ENSMUST00000051401.2
Cldn4
claudin 4
chr2_+_121449362 0.173 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr16_+_24721842 0.172 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr11_-_70255329 0.167 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr2_+_118900377 0.159 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr1_+_86021935 0.153 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr11_+_97315716 0.151 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr18_-_80713062 0.142 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr17_-_32388885 0.140 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr13_-_54688246 0.137 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr5_+_72914554 0.127 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr14_-_55106547 0.121 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr11_-_97699634 0.114 ENSMUST00000103148.1
ENSMUST00000169807.1
Pcgf2

polycomb group ring finger 2

chr7_-_141434532 0.092 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr11_+_101070012 0.089 ENSMUST00000001802.9
Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr9_+_55208925 0.087 ENSMUST00000034859.8
Fbxo22
F-box protein 22
chr1_+_131910458 0.085 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_29547820 0.079 ENSMUST00000102844.3
Rps27a
ribosomal protein S27A
chr10_-_128547722 0.078 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr7_+_102229999 0.073 ENSMUST00000120119.1
Pgap2
post-GPI attachment to proteins 2
chr2_+_112265809 0.072 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chrX_+_10485121 0.066 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr2_-_73911323 0.063 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr2_-_136387929 0.060 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr17_+_28177339 0.057 ENSMUST00000073534.2
ENSMUST00000002318.1
Zfp523

zinc finger protein 523

chr13_-_54688264 0.042 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr18_+_60774675 0.035 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr6_+_147531392 0.029 ENSMUST00000111614.2
Ccdc91
coiled-coil domain containing 91
chr4_+_148000722 0.024 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr10_-_53647080 0.021 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr4_-_141664063 0.014 ENSMUST00000084203.4
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr18_+_60774510 0.011 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr16_-_76403673 0.007 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr2_-_119662756 0.007 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr2_+_151542483 0.006 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr12_-_111712946 0.004 ENSMUST00000160825.1
ENSMUST00000162953.1
Bag5

BCL2-associated athanogene 5

chr19_-_6980420 0.000 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 3.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.8 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.4 1.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.4 1.6 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.3 3.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 0.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.7 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 1.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 2.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 1.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 0.7 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.2 2.2 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 2.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.7 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.1 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.1 1.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.6 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.9 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.8 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0071472 rubidium ion transport(GO:0035826) cellular response to salt stress(GO:0071472) cellular hypotonic response(GO:0071476)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 2.2 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 3.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 5.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.5 GO:0000776 kinetochore(GO:0000776)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 2.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.4 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 2.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 4.0 GO:0001047 core promoter binding(GO:0001047)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 3.2 PID_ATM_PATHWAY ATM pathway
0.0 1.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 1.9 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 1.7 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.2 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 3.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation