Motif ID: Scrt1

Z-value: 1.230


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.307.4e-02Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_28511344 5.824 ENSMUST00000112272.1
 Wnt5a
wingless-related MMTV integration site 5A
chr1_+_185454803 5.793 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr11_-_100355383 5.614 ENSMUST00000146878.2
 Hap1
huntingtin-associated protein 1
chr11_+_115163333 5.361 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr9_+_91368811 5.311 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr5_-_114273702 5.198 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr5_+_33658567 4.977 ENSMUST00000114426.3
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_+_34649987 4.915 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr9_+_91368970 4.659 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_-_27155418 4.638 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr18_-_82406777 4.452 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr6_+_138140521 4.309 ENSMUST00000120939.1
ENSMUST00000120302.1
 Mgst1

microsomal glutathione S-transferase 1

chr6_+_128375456 4.272 ENSMUST00000100926.2
 4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr5_+_33658550 4.178 ENSMUST00000152847.1
 Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_-_44815658 4.021 ENSMUST00000107893.1
 Atf5
activating transcription factor 5
chr4_-_19570073 3.951 ENSMUST00000029885.4
 Cpne3
copine III
chr17_-_25570678 3.691 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr1_-_173942445 3.613 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr5_+_33658123 3.598 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr11_-_101466222 3.529 ENSMUST00000040430.7
 Vat1
vesicle amine transport protein 1 homolog (T californica)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 12.9 GO:0030953 astral microtubule organization(GO:0030953)
0.1 6.0 GO:0051592 response to calcium ion(GO:0051592)
1.9 5.8 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
1.9 5.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.1 5.6 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.8 5.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 5.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 5.1 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
1.0 4.9 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.5 4.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.5 4.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
1.5 4.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.1 4.3 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.7 4.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.0 4.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 4.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 3.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
1.2 3.7 GO:0072034 renal vesicle induction(GO:0072034)
0.9 3.5 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 3.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.2 GO:0005813 centrosome(GO:0005813)
0.1 11.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 7.7 GO:0055037 recycling endosome(GO:0055037)
0.1 7.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 5.6 GO:0005776 autophagosome(GO:0005776)
0.5 5.4 GO:0032426 stereocilium tip(GO:0032426)
0.8 4.6 GO:0033010 paranodal junction(GO:0033010)
0.9 4.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.4 3.4 GO:0033269 internode region of axon(GO:0033269)
0.1 3.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.4 GO:0000786 nucleosome(GO:0000786)
0.0 3.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.4 2.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 25.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 7.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 7.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
1.9 5.8 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 5.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 5.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.4 5.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 5.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 4.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
1.1 4.5 GO:0004966 galanin receptor activity(GO:0004966)
0.2 4.3 GO:0035198 miRNA binding(GO:0035198)
0.2 4.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 3.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 3.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 3.0 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 2.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 2.9 GO:0050700 CARD domain binding(GO:0050700)
0.2 2.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 9.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 5.4 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 4.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 4.6 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 4.0 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 3.8 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 3.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.8 PID_ATR_PATHWAY ATR signaling pathway
0.1 1.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 1.3 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 3.6 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 3.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 2.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 1.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 1.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription